In vitro and in vivo investigation of collagen - C-60(OH)(24) interaction
Abstract
In this paper both theoretical and experimental approach to a possible interaction between collagen hydrolyzate and fullerole C-60(OH)(24) have been considered. In vitro and in vivo experiments were performed. Based on FT-IR spectroscopy, bands of amide I, II and III, from collagen hydrolyzate were analyzed, as well as the characteristic bands of fullerole. Based on experimental results, torsion types of interaction between collagen hydrolyzate and fullerole C-60(OH)(24) have been considered. According to in vivo experiments, fullerole initiates fibroblast cells production and after a two-month skin treatment it improves collagen and elastin production. This indicates that fullerole effects intermolecular communications from collagen fibers through integrines and microtubules to cell nucleus.
Keywords:
torsion angles / skin biopsy / nano-twister / molecular biophysics / IR spectroscopy / harmony/disharmony / fullerole / feedback control / elastin / collagenSource:
Progress in Advanced Materials and Processes, 2004, 453-454, 561-566Publisher:
- Trans Tech Publications Ltd.
Note:
- Materials Science Forum 453-454
DOI: 10.4028/www.scientific.net/MSF.453-454.561
ISBN: 978-0878499403
ISSN: 0255-5476
WoS: 000221535700092
Scopus: 2-s2.0-3142659679
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - CONF AU - Matija, Lidija AU - Koruga, Đuro AU - Jovanović, J. AU - Dobrosavljević, D. AU - Ignjatović, Nenad PY - 2004 UR - https://dais.sanu.ac.rs/123456789/14302 AB - In this paper both theoretical and experimental approach to a possible interaction between collagen hydrolyzate and fullerole C-60(OH)(24) have been considered. In vitro and in vivo experiments were performed. Based on FT-IR spectroscopy, bands of amide I, II and III, from collagen hydrolyzate were analyzed, as well as the characteristic bands of fullerole. Based on experimental results, torsion types of interaction between collagen hydrolyzate and fullerole C-60(OH)(24) have been considered. According to in vivo experiments, fullerole initiates fibroblast cells production and after a two-month skin treatment it improves collagen and elastin production. This indicates that fullerole effects intermolecular communications from collagen fibers through integrines and microtubules to cell nucleus. PB - Trans Tech Publications Ltd. C3 - Progress in Advanced Materials and Processes T1 - In vitro and in vivo investigation of collagen - C-60(OH)(24) interaction SP - 561 EP - 566 VL - 453-454 DO - 10.4028/www.scientific.net/MSF.453-454.561 UR - https://hdl.handle.net/21.15107/rcub_machinery_399 ER -
@conference{ author = "Matija, Lidija and Koruga, Đuro and Jovanović, J. and Dobrosavljević, D. and Ignjatović, Nenad", year = "2004", abstract = "In this paper both theoretical and experimental approach to a possible interaction between collagen hydrolyzate and fullerole C-60(OH)(24) have been considered. In vitro and in vivo experiments were performed. Based on FT-IR spectroscopy, bands of amide I, II and III, from collagen hydrolyzate were analyzed, as well as the characteristic bands of fullerole. Based on experimental results, torsion types of interaction between collagen hydrolyzate and fullerole C-60(OH)(24) have been considered. According to in vivo experiments, fullerole initiates fibroblast cells production and after a two-month skin treatment it improves collagen and elastin production. This indicates that fullerole effects intermolecular communications from collagen fibers through integrines and microtubules to cell nucleus.", publisher = "Trans Tech Publications Ltd.", journal = "Progress in Advanced Materials and Processes", title = "In vitro and in vivo investigation of collagen - C-60(OH)(24) interaction", pages = "561-566", volume = "453-454", doi = "10.4028/www.scientific.net/MSF.453-454.561", url = "https://hdl.handle.net/21.15107/rcub_machinery_399" }
Matija, L., Koruga, Đ., Jovanović, J., Dobrosavljević, D.,& Ignjatović, N.. (2004). In vitro and in vivo investigation of collagen - C-60(OH)(24) interaction. in Progress in Advanced Materials and Processes Trans Tech Publications Ltd.., 453-454, 561-566. https://doi.org/10.4028/www.scientific.net/MSF.453-454.561 https://hdl.handle.net/21.15107/rcub_machinery_399
Matija L, Koruga Đ, Jovanović J, Dobrosavljević D, Ignjatović N. In vitro and in vivo investigation of collagen - C-60(OH)(24) interaction. in Progress in Advanced Materials and Processes. 2004;453-454:561-566. doi:10.4028/www.scientific.net/MSF.453-454.561 https://hdl.handle.net/21.15107/rcub_machinery_399 .
Matija, Lidija, Koruga, Đuro, Jovanović, J., Dobrosavljević, D., Ignjatović, Nenad, "In vitro and in vivo investigation of collagen - C-60(OH)(24) interaction" in Progress in Advanced Materials and Processes, 453-454 (2004):561-566, https://doi.org/10.4028/www.scientific.net/MSF.453-454.561 ., https://hdl.handle.net/21.15107/rcub_machinery_399 .