A new, simple, green, and one-pot four-component synthesis of bare and poly(α,γ, L-glutamic acid)-capped silver nanoparticles
Аутори
Stevanović, Magdalena
Savanović, Igor
Uskoković, Vuk

Škapin, Srečo Davor

Bračko, Ines
Jovanović, Uroš
Uskoković, Dragan

Чланак у часопису (Рецензирана верзија)
Метаподаци
Приказ свих података о документуАпстракт
A simple and green chemical method has been developed to synthesize stable bare and capped silver nanoparticles based on the reduction of silver ions by glucose and capping by poly(α,γ,L-glutamic acid) (PGA). The use of ammonia during synthesis was avoided. PGA has had a dual role in the synthesis and was used as a capping agent to make the silver nanoparticle more biocompatible and to protect the nanoparticles from agglomerating in the liquid medium. The synthesized PGA-capped silver nanoparticles in the size range 5–45 nm were stable over long periods of time, without signs of precipitation. Morphological examination has shown that the silver nanoparticles had a nearly spherical, multiply twinned structure. The effects of the reaction temperature and the reaction time during the synthesis were investigated too. The biocompatibility of the PGA-capped silver nano-particles is discussed in terms of in vitro toxicity with human intestinal Caco-2 cells. The samples were characterized by U...V–Visible spectroscopy, field emission scanning electron microscopy, transmission electron microscopy, and zeta potential measurements.
Кључне речи:
silver nanoparticles / green method / poly(α,γ,L-glutamic acid) / capping agent / in vitro toxicityИзвор:
Colloid and Polymer Science, 2012, 290, 3, 221-231Издавач:
- Springer-Verlag
Пројекти:
- Молекуларно дизајнирање наночестица контролисаних морфолошких и физичко-хемијских карактеристика и функционалних материјала на њиховој основи (RS-45004)
- United States National Institutes of Health (NIH), Grant K99-DE021416