Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites
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1999
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Besides its high osteoinductive properties, hydroxyapatite (HAp) exhibits a relatively low mechanical strength. In order to improve the mechanical properties and reliability of HAp based composites, the addition of selected polymers is highly recommended, The main objective of this work is to study the microstructural characteristics of HAp/poly-L-lactide (PLLA) composites obtained by cold or hot processing. The composites were prepared from a mixture of a chloroform solution of poly-L-lactide with granulated HAp. After elimination of chloroform by vacuum evaporation, dense compacts were obtained by cold or hot pressing. The pressing pressure ranged from 98.10 to 294.3 MPa for both cold and hot pressing, The hot pressing was performed in the temperature region 293-457 K for a time period of 15-60 min. Depending on the PLLA amount and the pressing procedure it is possible to obtain highly porous or nearly fully dense composites, The scanning electron microscopy examination of fracture a...s well as of free surfaces revealed that the final porosity and wetting are affected to a great extent by the synthesis conditions and amount of polymer added. An increase in temperature to 457 K for a longer period of time results in fully dense compacts, The formation of a nearly continuous polymer network that leads to the hardening of HAp has also been observed. However, it should be pointed out that some layers of HAp may be free of polymer film since PLLA penetrates more deeply into the porous HAp.
Ključne reči:
biomaterials / bone / Ca-hydroxyapatite / composites / interface / microstructure / phases / poly-L-lactide / pressing temperatureIzvor:
Journal of Microscopy, 1999, 196, 2, 243-248Izdavač:
- Wiley
DOI: 10.1046/j.1365-2818.1999.00623.x
ISSN: 0022-2720
WoS: 000083537100017
Scopus: 2-s2.0-0032725721
Institucija/grupa
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - JOUR AU - Ignjatović, Nenad AU - Plavšić, Milenko AU - Miljković, Miroslav AU - Živković, L. M. AU - Uskoković, Dragan PY - 1999 UR - https://dais.sanu.ac.rs/123456789/10667 AB - Besides its high osteoinductive properties, hydroxyapatite (HAp) exhibits a relatively low mechanical strength. In order to improve the mechanical properties and reliability of HAp based composites, the addition of selected polymers is highly recommended, The main objective of this work is to study the microstructural characteristics of HAp/poly-L-lactide (PLLA) composites obtained by cold or hot processing. The composites were prepared from a mixture of a chloroform solution of poly-L-lactide with granulated HAp. After elimination of chloroform by vacuum evaporation, dense compacts were obtained by cold or hot pressing. The pressing pressure ranged from 98.10 to 294.3 MPa for both cold and hot pressing, The hot pressing was performed in the temperature region 293-457 K for a time period of 15-60 min. Depending on the PLLA amount and the pressing procedure it is possible to obtain highly porous or nearly fully dense composites, The scanning electron microscopy examination of fracture as well as of free surfaces revealed that the final porosity and wetting are affected to a great extent by the synthesis conditions and amount of polymer added. An increase in temperature to 457 K for a longer period of time results in fully dense compacts, The formation of a nearly continuous polymer network that leads to the hardening of HAp has also been observed. However, it should be pointed out that some layers of HAp may be free of polymer film since PLLA penetrates more deeply into the porous HAp. PB - Wiley T2 - Journal of Microscopy T1 - Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites SP - 243 EP - 248 VL - 196 IS - 2 DO - 10.1046/j.1365-2818.1999.00623.x UR - https://hdl.handle.net/21.15107/rcub_dais_10667 ER -
@article{ author = "Ignjatović, Nenad and Plavšić, Milenko and Miljković, Miroslav and Živković, L. M. and Uskoković, Dragan", year = "1999", abstract = "Besides its high osteoinductive properties, hydroxyapatite (HAp) exhibits a relatively low mechanical strength. In order to improve the mechanical properties and reliability of HAp based composites, the addition of selected polymers is highly recommended, The main objective of this work is to study the microstructural characteristics of HAp/poly-L-lactide (PLLA) composites obtained by cold or hot processing. The composites were prepared from a mixture of a chloroform solution of poly-L-lactide with granulated HAp. After elimination of chloroform by vacuum evaporation, dense compacts were obtained by cold or hot pressing. The pressing pressure ranged from 98.10 to 294.3 MPa for both cold and hot pressing, The hot pressing was performed in the temperature region 293-457 K for a time period of 15-60 min. Depending on the PLLA amount and the pressing procedure it is possible to obtain highly porous or nearly fully dense composites, The scanning electron microscopy examination of fracture as well as of free surfaces revealed that the final porosity and wetting are affected to a great extent by the synthesis conditions and amount of polymer added. An increase in temperature to 457 K for a longer period of time results in fully dense compacts, The formation of a nearly continuous polymer network that leads to the hardening of HAp has also been observed. However, it should be pointed out that some layers of HAp may be free of polymer film since PLLA penetrates more deeply into the porous HAp.", publisher = "Wiley", journal = "Journal of Microscopy", title = "Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites", pages = "243-248", volume = "196", number = "2", doi = "10.1046/j.1365-2818.1999.00623.x", url = "https://hdl.handle.net/21.15107/rcub_dais_10667" }
Ignjatović, N., Plavšić, M., Miljković, M., Živković, L. M.,& Uskoković, D.. (1999). Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites. in Journal of Microscopy Wiley., 196(2), 243-248. https://doi.org/10.1046/j.1365-2818.1999.00623.x https://hdl.handle.net/21.15107/rcub_dais_10667
Ignjatović N, Plavšić M, Miljković M, Živković LM, Uskoković D. Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites. in Journal of Microscopy. 1999;196(2):243-248. doi:10.1046/j.1365-2818.1999.00623.x https://hdl.handle.net/21.15107/rcub_dais_10667 .
Ignjatović, Nenad, Plavšić, Milenko, Miljković, Miroslav, Živković, L. M., Uskoković, Dragan, "Microstructural characteristics of calcium hydroxyapatite/poly-L-lactide based composites" in Journal of Microscopy, 196, no. 2 (1999):243-248, https://doi.org/10.1046/j.1365-2818.1999.00623.x ., https://hdl.handle.net/21.15107/rcub_dais_10667 .