Synthetical bone-like and biological hydroxyapatites: a comparative study of crystal structure and morphology
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2011
Authors
Marković, Smilja
Veselinović, Ljiljana

Lukić, Miodrag J.

Karanović, Ljiljana

Bračko, Ines
Ignjatović, Nenad

Uskoković, Dragan

Article (Published version)

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Phase composition, crystal structure and morphology of biological hydroxyapatite (BHAp) extracted from human mandible bone, and carbonated hydroxyapatite (CHAp), synthesized by the chemical precipitation method, were studied by x-ray powder diffraction (XRD), Fourier transform infrared (FTIR) and Raman (R) spectroscopy techniques, combined with transmission electron microscopy (TEM). Structural and microstructural parameters were determined through Rietveld refinement of recorded XRD data, performed using the FullProf computing program, and TEM. Microstructural analysis shows anisotropic extension along the [0 0 l] crystallographic direction (i.e. elongated crystallites shape) of both investigated samples. The average crystallite sizes of 10 and 8 nm were estimated for BHAp and CHAp, respectively. The FTIR and R spectroscopy studies show that carbonate ions substitute both phosphate and hydroxyl ions in the crystal structure of BHAp as well as in CHAp, indicating that both of them are ...mixed AB-type of CHAp. The thermal behaviour and carbonate content were analysed using thermogravimetric and differential thermal analysis. The carbonate content of about 1 wt.% and phase transition, at near 790 °C, from HAp to β-tricalcium phosphate were determined in both samples. The quality of synthesized CHAp powder, particularly, the particle size distribution and uniformity of morphology, was analysed by a particle size analyser based on laser diffraction and field emission scanning electron microscopy, respectively. These data were used to discuss similarity between natural and synthetic CHAp. Good correlation between the unit cell parameters, average crystallite size, morphology, carbonate content and crystallographic positions of carbonate ions in natural and synthetic HAp samples was found.
Keywords:
biological hydroxyapatite / crystal structure / morphology / FTIR / Raman spectroscopySource:
Biomedical Materials, 2011, 6, -Art. No. 045005Publisher:
- IOP Publishing
Funding / projects:
DOI: 10.1088/1748-6041/6/4/045005
ISSN: 1748-605X (Online); 1748-6041 (Print)
WoS: 000292889900005
Scopus: 2-s2.0-80051950087
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - JOUR AU - Marković, Smilja AU - Veselinović, Ljiljana AU - Lukić, Miodrag J. AU - Karanović, Ljiljana AU - Bračko, Ines AU - Ignjatović, Nenad AU - Uskoković, Dragan PY - 2011 UR - https://dais.sanu.ac.rs/123456789/731 AB - Phase composition, crystal structure and morphology of biological hydroxyapatite (BHAp) extracted from human mandible bone, and carbonated hydroxyapatite (CHAp), synthesized by the chemical precipitation method, were studied by x-ray powder diffraction (XRD), Fourier transform infrared (FTIR) and Raman (R) spectroscopy techniques, combined with transmission electron microscopy (TEM). Structural and microstructural parameters were determined through Rietveld refinement of recorded XRD data, performed using the FullProf computing program, and TEM. Microstructural analysis shows anisotropic extension along the [0 0 l] crystallographic direction (i.e. elongated crystallites shape) of both investigated samples. The average crystallite sizes of 10 and 8 nm were estimated for BHAp and CHAp, respectively. The FTIR and R spectroscopy studies show that carbonate ions substitute both phosphate and hydroxyl ions in the crystal structure of BHAp as well as in CHAp, indicating that both of them are mixed AB-type of CHAp. The thermal behaviour and carbonate content were analysed using thermogravimetric and differential thermal analysis. The carbonate content of about 1 wt.% and phase transition, at near 790 °C, from HAp to β-tricalcium phosphate were determined in both samples. The quality of synthesized CHAp powder, particularly, the particle size distribution and uniformity of morphology, was analysed by a particle size analyser based on laser diffraction and field emission scanning electron microscopy, respectively. These data were used to discuss similarity between natural and synthetic CHAp. Good correlation between the unit cell parameters, average crystallite size, morphology, carbonate content and crystallographic positions of carbonate ions in natural and synthetic HAp samples was found. PB - IOP Publishing T2 - Biomedical Materials T1 - Synthetical bone-like and biological hydroxyapatites: a comparative study of crystal structure and morphology EP - Art. No. 045005 VL - 6 DO - 10.1088/1748-6041/6/4/045005 UR - https://hdl.handle.net/21.15107/rcub_dais_731 ER -
@article{ author = "Marković, Smilja and Veselinović, Ljiljana and Lukić, Miodrag J. and Karanović, Ljiljana and Bračko, Ines and Ignjatović, Nenad and Uskoković, Dragan", year = "2011", abstract = "Phase composition, crystal structure and morphology of biological hydroxyapatite (BHAp) extracted from human mandible bone, and carbonated hydroxyapatite (CHAp), synthesized by the chemical precipitation method, were studied by x-ray powder diffraction (XRD), Fourier transform infrared (FTIR) and Raman (R) spectroscopy techniques, combined with transmission electron microscopy (TEM). Structural and microstructural parameters were determined through Rietveld refinement of recorded XRD data, performed using the FullProf computing program, and TEM. Microstructural analysis shows anisotropic extension along the [0 0 l] crystallographic direction (i.e. elongated crystallites shape) of both investigated samples. The average crystallite sizes of 10 and 8 nm were estimated for BHAp and CHAp, respectively. The FTIR and R spectroscopy studies show that carbonate ions substitute both phosphate and hydroxyl ions in the crystal structure of BHAp as well as in CHAp, indicating that both of them are mixed AB-type of CHAp. The thermal behaviour and carbonate content were analysed using thermogravimetric and differential thermal analysis. The carbonate content of about 1 wt.% and phase transition, at near 790 °C, from HAp to β-tricalcium phosphate were determined in both samples. The quality of synthesized CHAp powder, particularly, the particle size distribution and uniformity of morphology, was analysed by a particle size analyser based on laser diffraction and field emission scanning electron microscopy, respectively. These data were used to discuss similarity between natural and synthetic CHAp. Good correlation between the unit cell parameters, average crystallite size, morphology, carbonate content and crystallographic positions of carbonate ions in natural and synthetic HAp samples was found.", publisher = "IOP Publishing", journal = "Biomedical Materials", title = "Synthetical bone-like and biological hydroxyapatites: a comparative study of crystal structure and morphology", pages = "Art. No. 045005", volume = "6", doi = "10.1088/1748-6041/6/4/045005", url = "https://hdl.handle.net/21.15107/rcub_dais_731" }
Marković, S., Veselinović, L., Lukić, M. J., Karanović, L., Bračko, I., Ignjatović, N.,& Uskoković, D.. (2011). Synthetical bone-like and biological hydroxyapatites: a comparative study of crystal structure and morphology. in Biomedical Materials IOP Publishing., 6. https://doi.org/10.1088/1748-6041/6/4/045005 https://hdl.handle.net/21.15107/rcub_dais_731
Marković S, Veselinović L, Lukić MJ, Karanović L, Bračko I, Ignjatović N, Uskoković D. Synthetical bone-like and biological hydroxyapatites: a comparative study of crystal structure and morphology. in Biomedical Materials. 2011;6:null-Art. No. 045005. doi:10.1088/1748-6041/6/4/045005 https://hdl.handle.net/21.15107/rcub_dais_731 .
Marković, Smilja, Veselinović, Ljiljana, Lukić, Miodrag J., Karanović, Ljiljana, Bračko, Ines, Ignjatović, Nenad, Uskoković, Dragan, "Synthetical bone-like and biological hydroxyapatites: a comparative study of crystal structure and morphology" in Biomedical Materials, 6 (2011), https://doi.org/10.1088/1748-6041/6/4/045005 ., https://hdl.handle.net/21.15107/rcub_dais_731 .