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Inert atmosphere processing of hydroxyapatite in the presence of lithium iron phosphate
(Journal of the European Ceramic Society, 2018)
The present study describes sintering behaviour of hydroxyapatite (HAp) upon addition of lithium iron phosphate (LFP) (1-10 wt.%) system in inert (Ar) atmosphere. The interaction between materials and melting of LFP ...
Hydroxyapatite nanopowders prepared in the presence of zirconium ions
(Elsevier, 2014)
Hydroxyapatite nanopowders were prepared in the presence of different concentrations of zirconium ions. Such crystallization conditions yielded significantly reduced particle size and increased specific surface area. Cell ...
Chitosan oligosaccharide lactate coated hydroxyapatite nanoparticles as a vehicle for the delivery of steroid drugs and the targeting of breast cancer cells
(Royal Society of Chemistry, 2018)
Low targeting efficiency and fast metabolism of antineoplastic drugs are hindrances to effective chemotherapies and there is an ongoing search for better drugs, but also better carriers. Steroid derivatives, 3β-hydroxy-1 ...
The effect of the androstane lung cancer inhibitor content on the cell-selective toxicity of hydroxyapatite-chitosan-PLGA nanocomposites
(Elsevier, 2018)
An androstane (17β-hydroxy-17α-picolyl-androst-5-en-3β-yl-acetate (derivative A)) cancer inhibitor was successfully captured in a carrier made of nano-sized hydroxyapatite (HAp) coated with chitosan-PLGA polymer blends ...
Chitosan-PLGA polymer blends as coatings for hydroxyapatite nanoparticles and their effect on antimicrobial properties, osteoconductivity and regeneration of osseous tissues
(Materials science & engineering. C, Materials for biological applications, 2016)
Composite biomaterials comprising nanostructured hydroxyapatite (HAp) have an enormous potential for natural bone tissue reparation, filling and augmentation. Chitosan (Ch) as a naturally derived polymer has many physicochemical ...
Selective anticancer activity of hydroxyapatite/chitosan-poly(D,L)-lactide-co-glycolide particles loaded with an androstane-based cancer inhibitor
(Colloids and Surfaces B: Biointerfaces, 2016)
In an earlier study we demonstrated that hydroxyapatite nanoparticles coated with chitosan-poly(d,l)-lactide-co-glycolide (HAp/Ch-PLGA) target lungs following their intravenous injection into mice. In this study we utilize ...
Mg/Cu co-substituted hydroxyapatite – Biocompatibility, mechanical properties and antimicrobial activity
(Elsevier, 2019)
The aim of this study was to improve the mechanical properties and to optimize antimicrobial activity of hydroxyapatite (HAP) by simultaneous doping with Mg and Cu ions in order to obtain material that would be able to ...
Hydrothermally processed 1D hydroxyapatite: Mechanism of formation and biocompatibility studies
(Materials Science and Engineering: C, 2016)
Recent developments in bone tissue engineering have led to an increased interest in one-dimensional (1D) hydroxyapatite (HA) nano- and micro-structures such as wires, ribbons and tubes. They have been proposed for use as ...
Nanosized hydroxyapatite and other calcium phosphates: Chemistry of formation and application as drug and gene delivery agents
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2011)
The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the basic mineral constituent of mammalian hard tissues, including the physicochemical features that govern its formation by ...