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Chitosan oligosaccharide lactate coated hydroxyapatite nanoparticles as a vehicle for the delivery of steroid drugs and the targeting of breast cancer cells
(Royal Society of Chemistry, 2018)
Low targeting efficiency and fast metabolism of antineoplastic drugs are hindrances to effective chemotherapies and there is an ongoing search for better drugs, but also better carriers. Steroid derivatives, 3β-hydroxy-1 ...
The effect of the androstane lung cancer inhibitor content on the cell-selective toxicity of hydroxyapatite-chitosan-PLGA nanocomposites
(Elsevier, 2018)
An androstane (17β-hydroxy-17α-picolyl-androst-5-en-3β-yl-acetate (derivative A)) cancer inhibitor was successfully captured in a carrier made of nano-sized hydroxyapatite (HAp) coated with chitosan-PLGA polymer blends ...
Inert atmosphere processing of hydroxyapatite in the presence of lithium iron phosphate
(Journal of the European Ceramic Society, 2018)
The present study describes sintering behaviour of hydroxyapatite (HAp) upon addition of lithium iron phosphate (LFP) (1-10 wt.%) system in inert (Ar) atmosphere. The interaction between materials and melting of LFP ...
Hydroxyapatite nanopowders prepared in the presence of zirconium ions
(Elsevier, 2014)
Hydroxyapatite nanopowders were prepared in the presence of different concentrations of zirconium ions. Such crystallization conditions yielded significantly reduced particle size and increased specific surface area. Cell ...
Mechanochemical synthesis of nanostructured fluorapatite/fluorhydroxyapatite and carbonated fluorapatite/fluorhydroxyapatite
(Journal of Solid State Chemistry, 2004)
Powder mixture of Ca(OH)(2)-P2O5-CaF2 were milled in planetary ball mill. A carbonated fluorhydroxyapatite, FHA Ca-10(PO4)(1-y)(CO3)(y)(PO4)(5)(OH)(2-2x1)(F)(2x1) was formed after 5 h of milling and carbonated fluoroapatite ...
Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial
(Radiation Physics and Chemistry, 2007)
The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly L-lactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal ...
Multifunctional hydroxyapatite and poly(D,L-lactide-co-glycolide) nanoparticles for the local delivery of cholecalciferol
(Elsevier, 2013)
Cholecalciferol, vitamin D3, plays an important role in bone metabolism by regulating extracellular levels of calcium. Presented here is a study on the effects of the local delivery of cholecalciferol (D3) using nanoparticulate ...
Inert atmosphere processing of hydroxyapatite in the presence of lithium iron phosphate
(Journal of the European Ceramic Society, 2018)
The present study describes sintering behaviour of hydroxyapatite (HAp) upon addition of lithium iron phosphate (LFP) (1-10 wt.%) system in inert (Ar) atmosphere. The interaction between materials and melting of LFP ...
Chitosan-PLGA polymer blends as coatings for hydroxyapatite nanoparticles and their effect on antimicrobial properties, osteoconductivity and regeneration of osseous tissues
(Materials science & engineering. C, Materials for biological applications, 2016)
Composite biomaterials comprising nanostructured hydroxyapatite (HAp) have an enormous potential for natural bone tissue reparation, filling and augmentation. Chitosan (Ch) as a naturally derived polymer has many physicochemical ...
Hydroxyapatite/poly-L-lactide (Collagen) biocomposite with poly-L-lactide of different molecular weights
(Weinheim : Wiley-VCH Verlag, 2000)
In this communication we describe the preparation of HAp/PLLA biocomposites by hot pressing of HAp powder with PLLA of different molecular weights, with and without the addition of collagen. We made PLLA of low molecular ...