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In Vitro Evaluation of Nanoscale Hydroxyapatite-Based Bone Reconstructive Materials with Antimicrobial Properties
(American Scientific Publishers, 2016)
In the field of oral implantology the loss of bone tissue prevents adequate patient care, and calls for the use of synthetic biomaterials with properties that resemble natural bone. Special attention is paid to the risk ...
Nanosized hydroxyapatite and other calcium phosphates: Chemistry of formation and application as drug and gene delivery agents
(Hoboken, NJ : John Wiley & Sons, 2011)
The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the basic mineral constituent of mammalian hard tissues, including the physicochemical features that govern its formation by ...
Hydroxyapatite/TiO2 Nanomaterial with Defined Microstructural and Good Antimicrobial Properties
(Antibiotics, 2022)
Due to the growing number of people infected with the new coronavirus globally, which weakens immunity, there has been an increase in bacterial infections. Hence, knowledge about simple and low-cost synthesis methods of ...
Hydroxyapatite as a root canal system filling material: Cytotoxicity testing
(Durnten-Zurich : Trans Tech Publications Ltd., 2004)
Cytotoxicity testing, as a standard assay for toxicity of dental materials, is useful for initial biocompatibility evaluations. In vitro test of calcium hydroxyapatite (CHA) with established laboratory cell line showed ...
Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial
(Radiation Physics and Chemistry, 2007)
The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly L-lactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal ...
Mg/Cu co-substituted hydroxyapatite – Biocompatibility, mechanical properties and antimicrobial activity
(Elsevier, 2019)
The aim of this study was to improve the mechanical properties and to optimize antimicrobial activity of hydroxyapatite (HAP) by simultaneous doping with Mg and Cu ions in order to obtain material that would be able to ...
Synthesis and Characterization of Hydroxyapatite/Fullerenol Nanocomposites
(Journal of Nanoscience and Nanotechnology, 2015)
Fullerenols are polyhydroxylated, water soluble derivatives of fullerene C60, with potential application in medicine as diagnostic agents, antioxidants or nano drug carriers. This paper describes synthesis and physical ...
Multifunctional hydroxyapatite and poly(D,L-lactide-co-glycolide) nanoparticles for the local delivery of cholecalciferol
(Elsevier, 2013)
Cholecalciferol, vitamin D3, plays an important role in bone metabolism by regulating extracellular levels of calcium. Presented here is a study on the effects of the local delivery of cholecalciferol (D3) using nanoparticulate ...
The effect of the androstane lung cancer inhibitor content on the cell-selective toxicity of hydroxyapatite-chitosan-PLGA nanocomposites
(Elsevier, 2018)
An androstane (17β-hydroxy-17α-picolyl-androst-5-en-3β-yl-acetate (derivative A)) cancer inhibitor was successfully captured in a carrier made of nano-sized hydroxyapatite (HAp) coated with chitosan-PLGA polymer blends ...
Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics
(Royal Society of Chemistry, 2021)
Amorphous calcium phosphate (ACP) is a material of high interest for dentistry, orthopedics, and other biomedical sectors. Being intrinsically metastable, the process of transformation of ACP into a crystalline phase upon ...