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Assessment of the effects of nanoparticles of CP/PLGA on cultures of different cell lines

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2011
695.pdf (65.92Kb)
Authors
Najman, Stevo
Stojanović, Sanja
Najdanović, Jelena
Ignjatović, Nenad
Uskoković, Dragan
Conference object (Published version)
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Abstract
The aim of this study was to examine the effects of nanoparticles of calcium phosphate/poly-(DL-lactide-co-glycolide) (NPs-CP/PLGA) on viability and growth of different cell lines in vitro. HeLa and MDCK cells were incubated with different concentrations of suspension and extract of NPs-CP/PLGA. Concentrations of suspension were in the range from 1.6 μg/ml to 5000 μg/ml and extract in the range from 2.5% to 50%. After incubation, MTT test was performed. Our results indicate that examined nanomaterial shows different effects depending on type of the cells, applied concentration of nanomaterial as well as whether it is examined suspension or extract.
Keywords:
calcium phosphate / poly- (DL-lactide-co-glycolide) / PLGA / cell lines / biomaterials
Source:
Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia, 2011, 6-6
Publisher:
  • Belgrade : Institute of Technical Sciences of SASA
Projects:
  • Molecular designing of nanoparticles with controlled morphological and physicochemical characteristics and functional materials based on them (RS-45004)
  • Virtual human osteoarticular system and its application in preclinical and clinical practice (RS-41017)

ISBN: 9788680321271

[ Google Scholar ]
URI
http://dais.sanu.ac.rs/123456789/698
Collections
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
Institution
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Najman, Stevo
AU  - Stojanović, Sanja
AU  - Najdanović, Jelena
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2011
UR  - http://dais.sanu.ac.rs/123456789/698
AB  - The aim of this study was to examine the effects of nanoparticles of calcium phosphate/poly-(DL-lactide-co-glycolide) (NPs-CP/PLGA) on viability and growth of different cell lines in vitro. HeLa and MDCK cells were incubated with different concentrations of suspension and extract of NPs-CP/PLGA. Concentrations of suspension were in the range from 1.6 μg/ml to 5000 μg/ml and extract in the range from 2.5% to 50%. After incubation, MTT test was performed. Our results indicate that examined nanomaterial shows different effects depending on type of the cells, applied concentration of nanomaterial as well as whether it is examined suspension or extract.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia
T1  - Assessment of the effects of nanoparticles of CP/PLGA on cultures of different cell lines
SP  - 6
EP  - 6
ER  - 
@conference{
author = "Najman, Stevo and Stojanović, Sanja and Najdanović, Jelena and Ignjatović, Nenad and Uskoković, Dragan",
year = "2011",
url = "http://dais.sanu.ac.rs/123456789/698",
abstract = "The aim of this study was to examine the effects of nanoparticles of calcium phosphate/poly-(DL-lactide-co-glycolide) (NPs-CP/PLGA) on viability and growth of different cell lines in vitro. HeLa and MDCK cells were incubated with different concentrations of suspension and extract of NPs-CP/PLGA. Concentrations of suspension were in the range from 1.6 μg/ml to 5000 μg/ml and extract in the range from 2.5% to 50%. After incubation, MTT test was performed. Our results indicate that examined nanomaterial shows different effects depending on type of the cells, applied concentration of nanomaterial as well as whether it is examined suspension or extract.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia",
title = "Assessment of the effects of nanoparticles of CP/PLGA on cultures of different cell lines",
pages = "6-6"
}
Najman S, Stojanović S, Najdanović J, Ignjatović N, Uskoković D. Assessment of the effects of nanoparticles of CP/PLGA on cultures of different cell lines. Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia. 2011;:6-6
Najman, S., Stojanović, S., Najdanović, J., Ignjatović, N.,& Uskoković, D. (2011). Assessment of the effects of nanoparticles of CP/PLGA on cultures of different cell lines.
Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, SerbiaBelgrade : Institute of Technical Sciences of SASA., null, 6-6. 
Najman Stevo, Stojanović Sanja, Najdanović Jelena, Ignjatović Nenad, Uskoković Dragan, "Assessment of the effects of nanoparticles of CP/PLGA on cultures of different cell lines" null (2011):6-6

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