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Application analysis of micro and nano composites in restoring of bone tissue of the jaw

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2007
bitstream_19701.pdf (236.7Kb)
Authors
Ajduković, Zorica
Ignjatović, Nenad
Petrović, Dragan
Savić, Vesna
Kaličanin, Biljana
Anđelković, Maja
Nikolov, S.
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Abstract
Application of synthetic polymer biomaterials is very often used in biomedicine and dentistry. That’s why the need for creating the new polymer biomaterials is more and more obvious. Hydroxy-apatite, as a natural constituent of bone, has been already used for many years in all segments of dentistry. In order to develop better properties, hydroxy-apatite is combined with polymers. In this research, application of micro and nano composite biomaterials in reconstruction of osteoporosis damaged alveolar bone of rats is analyzed. Evaluation of regeneration of restored osteoporosis damaged alveolar bone of rats was done by histopathological analyses. The optimal results were after 24 weeks after implantation of calcium-phosphate/poly-D, L-lactide-co-glycolide (CP/DLPLG) composite biomaterials nano particles in comparison to micro particles. Regeneration and reparation of damaged alveolar bone with creation of new bone tissue which is very similar to mature bone, are much better on ... the place of nano CP/DLPLG implantation. Because of its very good osteoconductive effect, applied nano CP/DLPLG composite can totally renew lost bone tissue, so it can be the material of choice for the alveolar bone defect rehabilitation.

Keywords:
hydroxy-apatite / dentistry / histopathological analyses / calcium-phosphate/poly-D, L-lactide-co-glycolide (CP/DLPLG) / hidroksiapatit / stomatologija / histopatološke analize / kalcijum-fosfat poli-dl-laktid-ko-glikolid (CP/DLPLG)
Source:
Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007, 2007, 178-178
Publisher:
  • Belgrade : Institute of Technical Sciences of SASA
Projects:
  • Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (RS-142006)
  • Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija (RS-145068)

ISBN: 9788680321110

[ Google Scholar ]
URI
http://dais.sanu.ac.rs/123456789/6295
Collections
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
Institution
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, Dragan
AU  - Savić, Vesna
AU  - Kaličanin, Biljana
AU  - Anđelković, Maja
AU  - Nikolov, S.
PY  - 2007
UR  - http://dais.sanu.ac.rs/123456789/6295
AB  - Application of synthetic polymer biomaterials is very often used in biomedicine and
dentistry. That’s why the need for creating the new polymer biomaterials is more and more
obvious. Hydroxy-apatite, as a natural constituent of bone, has been already used for many years
in all segments of dentistry. In order to develop better properties, hydroxy-apatite is combined
with polymers. In this research, application of micro and nano composite biomaterials in
reconstruction of osteoporosis damaged alveolar bone of rats is analyzed. Evaluation of
regeneration of restored osteoporosis damaged alveolar bone of rats was done by
histopathological analyses. The optimal results were after 24 weeks after implantation of
calcium-phosphate/poly-D, L-lactide-co-glycolide (CP/DLPLG) composite biomaterials nano
particles in comparison to micro particles. Regeneration and reparation of damaged alveolar
bone with creation of new bone tissue which is very similar to mature bone, are much better on
the place of nano CP/DLPLG implantation. Because of its very good osteoconductive effect,
applied nano CP/DLPLG composite can totally renew lost bone tissue, so it can be the material
of choice for the alveolar bone defect rehabilitation.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
T1  - Application analysis of micro and nano composites in restoring of bone tissue of the jaw
SP  - 178
EP  - 178
ER  - 
@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, Dragan and Savić, Vesna and Kaličanin, Biljana and Anđelković, Maja and Nikolov, S.",
year = "2007",
url = "http://dais.sanu.ac.rs/123456789/6295",
abstract = "Application of synthetic polymer biomaterials is very often used in biomedicine and
dentistry. That’s why the need for creating the new polymer biomaterials is more and more
obvious. Hydroxy-apatite, as a natural constituent of bone, has been already used for many years
in all segments of dentistry. In order to develop better properties, hydroxy-apatite is combined
with polymers. In this research, application of micro and nano composite biomaterials in
reconstruction of osteoporosis damaged alveolar bone of rats is analyzed. Evaluation of
regeneration of restored osteoporosis damaged alveolar bone of rats was done by
histopathological analyses. The optimal results were after 24 weeks after implantation of
calcium-phosphate/poly-D, L-lactide-co-glycolide (CP/DLPLG) composite biomaterials nano
particles in comparison to micro particles. Regeneration and reparation of damaged alveolar
bone with creation of new bone tissue which is very similar to mature bone, are much better on
the place of nano CP/DLPLG implantation. Because of its very good osteoconductive effect,
applied nano CP/DLPLG composite can totally renew lost bone tissue, so it can be the material
of choice for the alveolar bone defect rehabilitation.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007",
title = "Application analysis of micro and nano composites in restoring of bone tissue of the jaw",
pages = "178-178"
}
Ajduković Z, Ignjatović N, Petrović D, Savić V, Kaličanin B, Anđelković M, Nikolov S. Application analysis of micro and nano composites in restoring of bone tissue of the jaw. Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007. 2007;:178-178
Ajduković, Z., Ignjatović, N., Petrović, D., Savić, V., Kaličanin, B., Anđelković, M.,& Nikolov, S. (2007). Application analysis of micro and nano composites in restoring of bone tissue of the jaw.
Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007Belgrade : Institute of Technical Sciences of SASA., null, 178-178. 
Ajduković Zorica, Ignjatović Nenad, Petrović Dragan, Savić Vesna, Kaličanin Biljana, Anđelković Maja, Nikolov S., "Application analysis of micro and nano composites in restoring of bone tissue of the jaw" null (2007):178-178

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