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Osteogenic activity in a mice subcutaneous implant of porous hydroxyapatite/poly-L-lactide loaded with bone marrow cells

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2007
bitstream_19684.pdf (237.8Kb)
Authors
Janićijević, Jelena
Najman, Stevo
Vukelić, Marija
Ignjatović, Nenad
Uskoković, Dragan
Đorđević, Ljubiša
Vasiljević, Perica
Conference object (Published version)
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Abstract
Hydroxyapatite (HAp) is biomaterial widely used in the regeneration of bone tissue. Addition of osteogenic cells to HAp implants may accelerate the bone repair process. The aim of this study was to investigate how the bone marrow cells (BMCs) loading of porous hydroxyapatite/poly-L-lactide (HAp/PLLA) act to ectopic osteogenesis. In this purpose HAp/PLLA with and without BMCs was subcutaneously implanted into BALB/c mice. As a control served implants from both types which weren’t implanted. Three weeks after implantation, histological analysis of implants was done. It was observed significant resorption and induction of collagenogenesis in implanted biomaterials. The structure of new bone was seen in implants loaded with bone marrow cells.
Keywords:
hydroxyapatite (HAp) / bone marrow cells (BMCs) / implanted biomaterials / Hidroksipatit (Hap) / ćelije koštane srži / implantirani biomaterijali
Source:
Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007, 2007, 181-181
Publisher:
  • Belgrade : Institute of Technical Sciences of SASA
Projects:
  • Regeneracija skeletnih tkiva pomognuta biomaterijalima kao tkivnim matricama - in vivo i in vitro studija (RS-145072)
[ Google Scholar ]
URI
181
http://dais.sanu.ac.rs/123456789/6283
Collections
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
Institution
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Janićijević, Jelena
AU  - Najman, Stevo
AU  - Vukelić, Marija
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Đorđević, Ljubiša
AU  - Vasiljević, Perica
PY  - 2007
UR  - 181
UR  - http://dais.sanu.ac.rs/123456789/6283
AB  - Hydroxyapatite (HAp) is biomaterial widely used in the regeneration of bone tissue.
Addition of osteogenic cells to HAp implants may accelerate the bone repair process. The aim of
this study was to investigate how the bone marrow cells (BMCs) loading of porous
hydroxyapatite/poly-L-lactide (HAp/PLLA) act to ectopic osteogenesis. In this purpose
HAp/PLLA with and without BMCs was subcutaneously implanted into BALB/c mice. As a
control served implants from both types which weren’t implanted. Three weeks after
implantation, histological analysis of implants was done. It was observed significant resorption
and induction of collagenogenesis in implanted biomaterials. The structure of new bone was
seen in implants loaded with bone marrow cells.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
T1  - Osteogenic activity in a mice subcutaneous implant of porous hydroxyapatite/poly-L-lactide loaded with bone marrow cells
SP  - 181
EP  - 181
ER  - 
@conference{
author = "Janićijević, Jelena and Najman, Stevo and Vukelić, Marija and Ignjatović, Nenad and Uskoković, Dragan and Đorđević, Ljubiša and Vasiljević, Perica",
year = "2007",
url = "181, http://dais.sanu.ac.rs/123456789/6283",
abstract = "Hydroxyapatite (HAp) is biomaterial widely used in the regeneration of bone tissue.
Addition of osteogenic cells to HAp implants may accelerate the bone repair process. The aim of
this study was to investigate how the bone marrow cells (BMCs) loading of porous
hydroxyapatite/poly-L-lactide (HAp/PLLA) act to ectopic osteogenesis. In this purpose
HAp/PLLA with and without BMCs was subcutaneously implanted into BALB/c mice. As a
control served implants from both types which weren’t implanted. Three weeks after
implantation, histological analysis of implants was done. It was observed significant resorption
and induction of collagenogenesis in implanted biomaterials. The structure of new bone was
seen in implants loaded with bone marrow cells.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007",
title = "Osteogenic activity in a mice subcutaneous implant of porous hydroxyapatite/poly-L-lactide loaded with bone marrow cells",
pages = "181-181"
}
Janićijević J, Najman S, Vukelić M, Ignjatović N, Uskoković D, Đorđević L, Vasiljević P. Osteogenic activity in a mice subcutaneous implant of porous hydroxyapatite/poly-L-lactide loaded with bone marrow cells. Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007. 2007;:181-181
Janićijević, J., Najman, S., Vukelić, M., Ignjatović, N., Uskoković, D., Đorđević, L.,& Vasiljević, P. (2007). Osteogenic activity in a mice subcutaneous implant of porous hydroxyapatite/poly-L-lactide loaded with bone marrow cells.
Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007Belgrade : Institute of Technical Sciences of SASA., null, 181-181. 
Janićijević Jelena, Najman Stevo, Vukelić Marija, Ignjatović Nenad, Uskoković Dragan, Đorđević Ljubiša, Vasiljević Perica, "Osteogenic activity in a mice subcutaneous implant of porous hydroxyapatite/poly-L-lactide loaded with bone marrow cells" null (2007):181-181

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