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Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period

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2014
Authors
Mitić, Žarko
Najman, Stevo
Cakić, Milorad
Ajduković, Zorica
Ignjatović, Nenad
Nikolić, Ružica
Nikolić, Goran
Stojanović, Sanja
Vukelić, Marija Đ.
Trajanović, Miroslav
Article (Published version)
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Abstract
The influence of glucocorticoids on the composition and mineral/organic content of the mandible in tested animals after recovery and healing phase was investigated in this work. The results of FTIR analysis demonstrated that bone tissue composition was changed after glucocorticoid treatment. The increase of calcium, magnesium, phosphorus content and mineral part of bones was statistically significant in recovery phase and in treatment phase that included calcitonin and thymus extract. Some changes also happened in the organic part of the matrix, as indicated by intensity changes for already present IR bands and the appearance of new IR bands in the region 3500–1300 cm−1.
Keywords:
FTIR / glucocorticoids / mandible / AAS / minerals
Source:
Journal of Molecular Structure, 2014, 1074, 315-320
Publisher:
  • Elsevier
Projects:
  • Virtual human osteoarticular system and its application in preclinical and clinical practice (RS-41017)

DOI: 10.1016/j.molstruc.2014.06.006

ISSN: 0022-2860

WoS: 000340315200041

Scopus: 2-s2.0-84903718099
[ Google Scholar ]
5
2
URI
http://dais.sanu.ac.rs/123456789/554
Collections
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
Institution
Институт техничких наука САНУ / Institute of Technical Sciences of SASA

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