Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles
Authors
Ajduković, Zorica
Ignjatović, Nenad

Stojanović, Zoran S.

Kaličanin, Biljana
Savić, Vojin
Petrović, S. M.
Petrović, B. M.
Milićević, Jelena

Uskoković, Dragan

Conference object (Published version)
Metadata
Show full item recordAbstract
In this study nanocomposite was used for reconstruction of alveolar bone defect of mandible. Specifically, the main interest for the use of magnetic nanoparticles in biomedical applications is that an inhomogeneous external magnetic field exerts a force on them, and thus they can be manipulated or transported to a specific diseased tissue by a magnetic field gradient. In addition, magnetic particles are of interest because they do not retain any magnetism after removal of the magnetic field. Specifically, inorganic biodegradable nanoparticles (including ceramics, like hydroxyapatite) will be functionalized with bioactive compounds that bond to bone of low mass. Extremely good results in the recovery of alveolar bone osteoporosis were achieved already after 6th week of the application of magnetic nanoparticles. After bonding specifically to osteoporotic bone and not healthy bone, magnetic nanoparticle systems will deliver bioactive compounds to locally increase bone mass. Implantation o...f magnetic nanoparticles will create bone construction and enable quick formation of new bone and become the material of choice for accelerated bone regeneration.
Keywords:
osteoporosis / Ca/Co-HAp / magnetic nanoparticles / biomedical materialsSource:
Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009, 2009, 188-188Publisher:
- Belgrade : Institute of Technical Sciences of SASA
Funding / projects:
- Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (RS-142006)
- Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija (RS-145068)
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - CONF AU - Ajduković, Zorica AU - Ignjatović, Nenad AU - Stojanović, Zoran S. AU - Kaličanin, Biljana AU - Savić, Vojin AU - Petrović, S. M. AU - Petrović, B. M. AU - Milićević, Jelena AU - Uskoković, Dragan PY - 2009 UR - https://dais.sanu.ac.rs/123456789/4934 AB - In this study nanocomposite was used for reconstruction of alveolar bone defect of mandible. Specifically, the main interest for the use of magnetic nanoparticles in biomedical applications is that an inhomogeneous external magnetic field exerts a force on them, and thus they can be manipulated or transported to a specific diseased tissue by a magnetic field gradient. In addition, magnetic particles are of interest because they do not retain any magnetism after removal of the magnetic field. Specifically, inorganic biodegradable nanoparticles (including ceramics, like hydroxyapatite) will be functionalized with bioactive compounds that bond to bone of low mass. Extremely good results in the recovery of alveolar bone osteoporosis were achieved already after 6th week of the application of magnetic nanoparticles. After bonding specifically to osteoporotic bone and not healthy bone, magnetic nanoparticle systems will deliver bioactive compounds to locally increase bone mass. Implantation of magnetic nanoparticles will create bone construction and enable quick formation of new bone and become the material of choice for accelerated bone regeneration. PB - Belgrade : Institute of Technical Sciences of SASA C3 - Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009 T1 - Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles SP - 188 EP - 188 UR - https://hdl.handle.net/21.15107/rcub_dais_4934 ER -
@conference{ author = "Ajduković, Zorica and Ignjatović, Nenad and Stojanović, Zoran S. and Kaličanin, Biljana and Savić, Vojin and Petrović, S. M. and Petrović, B. M. and Milićević, Jelena and Uskoković, Dragan", year = "2009", abstract = "In this study nanocomposite was used for reconstruction of alveolar bone defect of mandible. Specifically, the main interest for the use of magnetic nanoparticles in biomedical applications is that an inhomogeneous external magnetic field exerts a force on them, and thus they can be manipulated or transported to a specific diseased tissue by a magnetic field gradient. In addition, magnetic particles are of interest because they do not retain any magnetism after removal of the magnetic field. Specifically, inorganic biodegradable nanoparticles (including ceramics, like hydroxyapatite) will be functionalized with bioactive compounds that bond to bone of low mass. Extremely good results in the recovery of alveolar bone osteoporosis were achieved already after 6th week of the application of magnetic nanoparticles. After bonding specifically to osteoporotic bone and not healthy bone, magnetic nanoparticle systems will deliver bioactive compounds to locally increase bone mass. Implantation of magnetic nanoparticles will create bone construction and enable quick formation of new bone and become the material of choice for accelerated bone regeneration.", publisher = "Belgrade : Institute of Technical Sciences of SASA", journal = "Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009", title = "Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles", pages = "188-188", url = "https://hdl.handle.net/21.15107/rcub_dais_4934" }
Ajduković, Z., Ignjatović, N., Stojanović, Z. S., Kaličanin, B., Savić, V., Petrović, S. M., Petrović, B. M., Milićević, J.,& Uskoković, D.. (2009). Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles. in Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009 Belgrade : Institute of Technical Sciences of SASA., 188-188. https://hdl.handle.net/21.15107/rcub_dais_4934
Ajduković Z, Ignjatović N, Stojanović ZS, Kaličanin B, Savić V, Petrović SM, Petrović BM, Milićević J, Uskoković D. Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles. in Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009. 2009;:188-188. https://hdl.handle.net/21.15107/rcub_dais_4934 .
Ajduković, Zorica, Ignjatović, Nenad, Stojanović, Zoran S., Kaličanin, Biljana, Savić, Vojin, Petrović, S. M., Petrović, B. M., Milićević, Jelena, Uskoković, Dragan, "Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles" in Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009 (2009):188-188, https://hdl.handle.net/21.15107/rcub_dais_4934 .