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dc.creatorĐurić, Zoran G.
dc.creatorJokić, Ivana
dc.creatorPeleš, Adriana
dc.date.accessioned2018-12-31T18:16:42Z
dc.date.available2016-06-10
dc.date.issued2014
dc.identifier.issn0167-9317
dc.identifier.urihttp://dais.sanu.ac.rs/123456789/4727
dc.description.abstractIn this study we have developed, for the first time, the comprehensive theoretical model of the fluctuations of the number of adsorbed molecules in MEMS chemical and biological sensors, taking into account the processes of mass transfer, adsorption and desorption, and surface diffusion of adsorbed molecules. It is observed that the shape of the fluctuations spectrum contains information about various parameters of the adsorbed analyte and that even the analytes with the same affinity for the same binding sites have different spectra. The numerical calculations performed using the derived theory show that the influence of surface diffusion on the fluctuations spectrum can be significant. The practical value of this work stems from the fact that the fluctuations of the number of adsorbed molecules can be a dominant noise component in affinity-based bio/chemical sensors. Therefore, the derived theory is useful for development of the methods for the detection of analytes based on frequency domain analysis of the measured fluctuations. The recognition of an adsorbed analyte using sensors with non-functionalized sensing surface will also be considered using the presented theory.en
dc.format124 (2014) 81-85
dc.languageen
dc.publisherElsevier
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172057/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/32008/RS//
dc.relationSerbian Academy of Sciences and Arts, Project F-150
dc.rightsembargoedAccess
dc.sourceMicroelectronic Engineeringen
dc.subjectchemical sensors
dc.subjectbiosensors
dc.subjectadsorption–desorption
dc.subjectmass transfer
dc.subjectsurface diffusion
dc.titleFluctuations of the number of adsorbed molecules due to adsorption–desorption processes coupled with mass transfer and surface diffusion in bio/chemical MEMS sensorsen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractЂурић, Зоран; Јокић, Ивана; Пелеш, Aдриана;
dc.citation.spage81
dc.citation.epage85
dc.citation.volume124
dc.identifier.wos000344825100016
dc.identifier.doi10.1016/j.mee.2014.06.001
dc.identifier.scopus2-s2.0-84903139520
dc.description.otherPoster: [http://dais.sanu.ac.rs/handle/123456789/552]
dc.description.otherThis is the peer-reviewed version of the article: Djurić, Z., Jokić, I., Peleš, A., 2014. Fluctuations of the number of adsorbed molecules due to adsorption–desorption processes coupled with mass transfer and surface diffusion in bio/chemical MEMS sensors. Microelectronic Engineering, Micro/Nano Biotechnologies and Systems 2013 124, 81–85. [https://doi.org/10.1016/j.mee.2014.06.001]
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dc.identifier.fulltexthttp://dais.sanu.ac.rs/bitstream/id/14772/10.1016@j.mee.2014.06.001.pdf


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