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dc.creatorStevanović, Magdalena
dc.date.accessioned2018-12-23T07:48:48Z
dc.date.available2018-12-23T07:48:48Z
dc.date.issued2018
dc.identifier.urihttp://dais.sanu.ac.rs/123456789/4668
dc.description.abstractDifferent medicaments (water-soluble vitamins), silver nanoparticles, selenium nanoparticles) have been successfully encapsulated into polyester micro and nanospheres thus creating nanoparticles with the various morphological characteristic. The crucial requirements for the controlled and balanced release of the medicament in the body are their ideal spherical shape and narrow size distribution. The size and shape of particles play the key role in their adhesion and interaction with the cell. Polymer degradation, also, plays a key role in medicament release from sustained release polyester systems, therefore in order to elucidate the mechanism governing release, it appears essential to analyze the in vitro degradation behavior of these devices. An integrated study of the nanosphere composition and structure was carried out by combining different techniques. In vitro degradation process and release tests, cytotoxicity, labeling polyester particles by 99mTc and biodistribution of PLGA nanoparticles without and with encapsulated medicament were examined.en
dc.language.isoensr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45004/RS//sr
dc.rightsopenAccesssr
dc.source8th Annual International Symposium of Drug Delivery Systems – 2018, Theme: Meeting the Challenges with Innovations, Time: July 19-21, 2018 / Place: Saint Petersburg, Russia : Conference Abstract Book of SDDS-2018sr
dc.subjectpolyester microparticlessr
dc.subjectpolyester nanoparticlessr
dc.subjectcontrolled drug deliverysr
dc.subjectnanomedicinesr
dc.titlePolyester micro- and nanospheres for controlled drug delivery, nanomedicine and other biomedical applications: progress and challengesen
dc.typeconferenceObjectsr
dc.rights.licenseBY-NC-NDsr
dcterms.abstractСтевановић, Магдалена;
dc.type.versionacceptedVersionsr
dc.identifier.fulltexthttp://dais.sanu.ac.rs/bitstream/id/14591/Stevanovic-SDDS-2018.pdf


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