Different medicaments (water-soluble vitamins), silver nanoparticles, selenium nanoparticles) have been successfully encapsulated into polyester micro and nanospheres thus creating nanoparticles with the various morphological characteristic. The crucial requirements for the controlled and balanced release of the medicament in the body are their ideal spherical shape and narrow size distribution. The size and shape of particles play the key role in their adhesion and interaction with the cell. Polymer degradation, also, plays a key role in medicament release from sustained release polyester systems, therefore in order to elucidate the mechanism governing release, it appears essential to analyze the in vitro degradation behavior of these devices. An integrated study of the nanosphere composition and structure was carried out by combining different techniques. In vitro degradation process and release tests, cytotoxicity, labeling polyester particles by 99mTc and biodistribution of PLGA na...noparticles without and with encapsulated medicament were examined.
8th Annual International Symposium of Drug Delivery Systems – 2018, Theme: Meeting the Challenges with Innovations, Time: July 19-21, 2018 / Place: Saint Petersburg, Russia : Conference Abstract Book of SDDS-2018, 2018
TY - CONF
AU - Stevanović, Magdalena
PY - 2018
UR - http://dais.sanu.ac.rs/123456789/4668
AB - Different medicaments (water-soluble vitamins), silver nanoparticles, selenium nanoparticles) have been successfully encapsulated into polyester micro and nanospheres thus creating nanoparticles with the various morphological characteristic. The crucial requirements for the controlled and balanced release of the medicament in the body are their ideal spherical shape and narrow size distribution. The size and shape of particles play the key role in their adhesion and interaction with the cell. Polymer degradation, also, plays a key role in medicament release from sustained release polyester systems, therefore in order to elucidate the mechanism governing release, it appears essential to analyze the in vitro degradation behavior of these devices. An integrated study of the nanosphere composition and structure was carried out by combining different techniques. In vitro degradation process and release tests, cytotoxicity, labeling polyester particles by 99mTc and biodistribution of PLGA nanoparticles without and with encapsulated medicament were examined.
C3 - 8th Annual International Symposium of Drug Delivery Systems – 2018, Theme: Meeting the Challenges with Innovations, Time: July 19-21, 2018 / Place: Saint Petersburg, Russia : Conference Abstract Book of SDDS-2018
T1 - Polyester micro- and nanospheres for controlled drug delivery, nanomedicine and other biomedical applications: progress and challenges
ER -
@conference{
author = "Stevanović, Magdalena",
year = "2018",
url = "http://dais.sanu.ac.rs/123456789/4668",
abstract = "Different medicaments (water-soluble vitamins), silver nanoparticles, selenium nanoparticles) have been successfully encapsulated into polyester micro and nanospheres thus creating nanoparticles with the various morphological characteristic. The crucial requirements for the controlled and balanced release of the medicament in the body are their ideal spherical shape and narrow size distribution. The size and shape of particles play the key role in their adhesion and interaction with the cell. Polymer degradation, also, plays a key role in medicament release from sustained release polyester systems, therefore in order to elucidate the mechanism governing release, it appears essential to analyze the in vitro degradation behavior of these devices. An integrated study of the nanosphere composition and structure was carried out by combining different techniques. In vitro degradation process and release tests, cytotoxicity, labeling polyester particles by 99mTc and biodistribution of PLGA nanoparticles without and with encapsulated medicament were examined.",
journal = "8th Annual International Symposium of Drug Delivery Systems – 2018, Theme: Meeting the Challenges with Innovations, Time: July 19-21, 2018 / Place: Saint Petersburg, Russia : Conference Abstract Book of SDDS-2018",
title = "Polyester micro- and nanospheres for controlled drug delivery, nanomedicine and other biomedical applications: progress and challenges"
}
Stevanović M. Polyester micro- and nanospheres for controlled drug delivery, nanomedicine and other biomedical applications: progress and challenges. 8th Annual International Symposium of Drug Delivery Systems – 2018, Theme: Meeting the Challenges with Innovations, Time: July 19-21, 2018 / Place: Saint Petersburg, Russia : Conference Abstract Book of SDDS-2018. 2018;
,& Stevanović, M. (2018). Polyester micro- and nanospheres for controlled drug delivery, nanomedicine and other biomedical applications: progress and challenges.
8th Annual International Symposium of Drug Delivery Systems – 2018, Theme: Meeting the Challenges with Innovations, Time: July 19-21, 2018 / Place: Saint Petersburg, Russia : Conference Abstract Book of SDDS-2018, null.
Stevanović Magdalena, "Polyester micro- and nanospheres for controlled drug delivery, nanomedicine and other biomedical applications: progress and challenges" null (2018)
