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Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors

Authorized Users Only
2018
Authors
Jokić, Ivana
Đurić, Zoran G.
Radulović, Katarina
Frantlović, Miloš
Article (Published version)
Metadata
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Abstract
We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
Keywords:
biosensors / competitive adsorption / deterministic time response / stochastic time response
Source:
Materials Today: Proceedings, 2018, 5, 8, Part 2, 16006-16011
Publisher:
  • Elsevier
Funding / projects:
  • Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection (RS-32008)

DOI: 10.1016/j.matpr.2018.05.045

ISSN: 2214-7853

WoS: 000441006800008

Scopus: 2-s2.0-85056510161
[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_dais_4550
URI
http://www.sciencedirect.com/science/article/pii/S2214785318309167
https://dais.sanu.ac.rs/123456789/4550
Collections
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - JOUR
AU  - Jokić, Ivana
AU  - Đurić, Zoran G.
AU  - Radulović, Katarina
AU  - Frantlović, Miloš
PY  - 2018
UR  - http://www.sciencedirect.com/science/article/pii/S2214785318309167
UR  - https://dais.sanu.ac.rs/123456789/4550
AB  - We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
PB  - Elsevier
T2  - Materials Today: Proceedings
T1  - Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors
SP  - 16006
EP  - 16011
VL  - 5
IS  - 8, Part 2
DO  - 10.1016/j.matpr.2018.05.045
UR  - https://hdl.handle.net/21.15107/rcub_dais_4550
ER  - 
@article{
author = "Jokić, Ivana and Đurić, Zoran G. and Radulović, Katarina and Frantlović, Miloš",
year = "2018",
abstract = "We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.",
publisher = "Elsevier",
journal = "Materials Today: Proceedings",
title = "Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors",
pages = "16006-16011",
volume = "5",
number = "8, Part 2",
doi = "10.1016/j.matpr.2018.05.045",
url = "https://hdl.handle.net/21.15107/rcub_dais_4550"
}
Jokić, I., Đurić, Z. G., Radulović, K.,& Frantlović, M.. (2018). Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors. in Materials Today: Proceedings
Elsevier., 5(8, Part 2), 16006-16011.
https://doi.org/10.1016/j.matpr.2018.05.045
https://hdl.handle.net/21.15107/rcub_dais_4550
Jokić I, Đurić ZG, Radulović K, Frantlović M. Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors. in Materials Today: Proceedings. 2018;5(8, Part 2):16006-16011.
doi:10.1016/j.matpr.2018.05.045
https://hdl.handle.net/21.15107/rcub_dais_4550 .
Jokić, Ivana, Đurić, Zoran G., Radulović, Katarina, Frantlović, Miloš, "Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors" in Materials Today: Proceedings, 5, no. 8, Part 2 (2018):16006-16011,
https://doi.org/10.1016/j.matpr.2018.05.045 .,
https://hdl.handle.net/21.15107/rcub_dais_4550 .

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