Adsorption–desorption noise in nanowire FET biosensors
Abstract
The adsorption-desorption (AD) noise in nanowire FET biosensors is analyzed, which manifests itself in the form of gate voltage fluctuations resulting from the fluctuations of the number of adsorbed particles. The derived theoretical model of the fluctuations takes into account the mass transfer effects. The numerical calculations show that when the mass transfer is slow, the low-frequency amplitude and the corner frequency of the Lorentzian AD noise spectrum obtained by derived expressions are significantly different compared to the same parameters predicted by the model that neglects mass transport effects. The presented analysis enables good estimation of these parameters from the measured noise spectrum, which is important because they are used as the source of information about the analyte concentration and the kinetics of biomolecular interactions.
Keywords:
adsorption–desorption / FET biosensors / noiseSource:
2012 28th International Conference on Microelectronics (MIEL), 2012, 203-206Publisher:
- IEEE
Funding / projects:
- Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection (RS-32008)
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - CONF AU - Radulović, Katarina AU - Jokić, Ivana AU - Frantlović, Miloš AU - Đurić, Zoran G. PY - 2012 UR - https://dais.sanu.ac.rs/123456789/450 AB - The adsorption-desorption (AD) noise in nanowire FET biosensors is analyzed, which manifests itself in the form of gate voltage fluctuations resulting from the fluctuations of the number of adsorbed particles. The derived theoretical model of the fluctuations takes into account the mass transfer effects. The numerical calculations show that when the mass transfer is slow, the low-frequency amplitude and the corner frequency of the Lorentzian AD noise spectrum obtained by derived expressions are significantly different compared to the same parameters predicted by the model that neglects mass transport effects. The presented analysis enables good estimation of these parameters from the measured noise spectrum, which is important because they are used as the source of information about the analyte concentration and the kinetics of biomolecular interactions. PB - IEEE C3 - 2012 28th International Conference on Microelectronics (MIEL) T1 - Adsorption–desorption noise in nanowire FET biosensors SP - 203 EP - 206 DO - 10.1109/MIEL.2012.6222834 UR - https://hdl.handle.net/21.15107/rcub_dais_450 ER -
@conference{ author = "Radulović, Katarina and Jokić, Ivana and Frantlović, Miloš and Đurić, Zoran G.", year = "2012", abstract = "The adsorption-desorption (AD) noise in nanowire FET biosensors is analyzed, which manifests itself in the form of gate voltage fluctuations resulting from the fluctuations of the number of adsorbed particles. The derived theoretical model of the fluctuations takes into account the mass transfer effects. The numerical calculations show that when the mass transfer is slow, the low-frequency amplitude and the corner frequency of the Lorentzian AD noise spectrum obtained by derived expressions are significantly different compared to the same parameters predicted by the model that neglects mass transport effects. The presented analysis enables good estimation of these parameters from the measured noise spectrum, which is important because they are used as the source of information about the analyte concentration and the kinetics of biomolecular interactions.", publisher = "IEEE", journal = "2012 28th International Conference on Microelectronics (MIEL)", title = "Adsorption–desorption noise in nanowire FET biosensors", pages = "203-206", doi = "10.1109/MIEL.2012.6222834", url = "https://hdl.handle.net/21.15107/rcub_dais_450" }
Radulović, K., Jokić, I., Frantlović, M.,& Đurić, Z. G.. (2012). Adsorption–desorption noise in nanowire FET biosensors. in 2012 28th International Conference on Microelectronics (MIEL) IEEE., 203-206. https://doi.org/10.1109/MIEL.2012.6222834 https://hdl.handle.net/21.15107/rcub_dais_450
Radulović K, Jokić I, Frantlović M, Đurić ZG. Adsorption–desorption noise in nanowire FET biosensors. in 2012 28th International Conference on Microelectronics (MIEL). 2012;:203-206. doi:10.1109/MIEL.2012.6222834 https://hdl.handle.net/21.15107/rcub_dais_450 .
Radulović, Katarina, Jokić, Ivana, Frantlović, Miloš, Đurić, Zoran G., "Adsorption–desorption noise in nanowire FET biosensors" in 2012 28th International Conference on Microelectronics (MIEL) (2012):203-206, https://doi.org/10.1109/MIEL.2012.6222834 ., https://hdl.handle.net/21.15107/rcub_dais_450 .