In this study we observed the changes in surface of nanoparticles of two different nanomaterials, cobalt-substituted hydroxyapatite (CoHAp) and calcium phosphate/poly-(DLlactide-co-glycolide) (CP/PLGA) that occurred under simulated physiological conditions in vitro. Both nanomaterials were incubated in an appropriate volume of Dulbecco's Modified Eagle Medium (DMEM) for 3 days at 37 0C and then the medium was removed and materials were dried. Surface changes of nanoparticles were studied by scanning electron microscopy (SEM). Results of SEM analysis show that changes in the size and shape of the nanoparticles took place. These changes can be explained by interactions of nanomaterials with DMEM. In the case of CP/PLGA it was probably the result of polymer degradation and changes in CoHAp nanoparticles were probably the result of ion exchange.
TY - CONF
AU - Stojanović, S.
AU - Mitić, Ž.
AU - Najman, Stevo
AU - Ignjatović, Nenad
AU - Uskoković, Dragan
PY - 2013
UR - https://dais.sanu.ac.rs/123456789/406
AB - In this study we observed the changes in surface of nanoparticles of two different nanomaterials, cobalt-substituted hydroxyapatite (CoHAp) and calcium phosphate/poly-(DLlactide-co-glycolide) (CP/PLGA) that occurred under simulated physiological conditions in vitro. Both nanomaterials were incubated in an appropriate volume of Dulbecco's Modified Eagle Medium (DMEM) for 3 days at 37 0C and then the medium was removed and materials were dried. Surface changes of nanoparticles were studied by scanning electron microscopy (SEM). Results of SEM analysis show that changes in the size and shape of the nanoparticles took place. These changes can be explained by interactions of nanomaterials with DMEM. In the case of CP/PLGA it was probably the result of polymer degradation and changes in CoHAp nanoparticles were probably the result of ion exchange.
PB - Belgrade : Materials Research Society of Serbia
C3 - The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts
T1 - Scanning electron microscopy study of changes in nanoparticles surface under in vitro simulated physiological conditions
SP - 149
EP - 149
UR - https://hdl.handle.net/21.15107/rcub_dais_406
ER -
@conference{
author = "Stojanović, S. and Mitić, Ž. and Najman, Stevo and Ignjatović, Nenad and Uskoković, Dragan",
year = "2013",
abstract = "In this study we observed the changes in surface of nanoparticles of two different nanomaterials, cobalt-substituted hydroxyapatite (CoHAp) and calcium phosphate/poly-(DLlactide-co-glycolide) (CP/PLGA) that occurred under simulated physiological conditions in vitro. Both nanomaterials were incubated in an appropriate volume of Dulbecco's Modified Eagle Medium (DMEM) for 3 days at 37 0C and then the medium was removed and materials were dried. Surface changes of nanoparticles were studied by scanning electron microscopy (SEM). Results of SEM analysis show that changes in the size and shape of the nanoparticles took place. These changes can be explained by interactions of nanomaterials with DMEM. In the case of CP/PLGA it was probably the result of polymer degradation and changes in CoHAp nanoparticles were probably the result of ion exchange.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts",
title = "Scanning electron microscopy study of changes in nanoparticles surface under in vitro simulated physiological conditions",
pages = "149-149",
url = "https://hdl.handle.net/21.15107/rcub_dais_406"
}
Stojanović, S., Mitić, Ž., Najman, S., Ignjatović, N.,& Uskoković, D.. (2013). Scanning electron microscopy study of changes in nanoparticles surface under in vitro simulated physiological conditions. in The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 149-149.
https://hdl.handle.net/21.15107/rcub_dais_406
Stojanović S, Mitić Ž, Najman S, Ignjatović N, Uskoković D. Scanning electron microscopy study of changes in nanoparticles surface under in vitro simulated physiological conditions. in The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts. 2013;:149-149.
https://hdl.handle.net/21.15107/rcub_dais_406 .
Stojanović, S., Mitić, Ž., Najman, Stevo, Ignjatović, Nenad, Uskoković, Dragan, "Scanning electron microscopy study of changes in nanoparticles surface under in vitro simulated physiological conditions" in The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts (2013):149-149,
https://hdl.handle.net/21.15107/rcub_dais_406 .
