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Stochastic time response of adsorption-based micro/nanobiosensors with a fluidic reaction chamber: The influence of mass transfer

Authorized Users Only
2017
Authors
Jokić, Ivana
Đurić, Zoran G.
Radulović, Katarina
Frantlović, Miloš
Conference object (Published version)
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Abstract
An approximate model for efficient analysis of stochastic time response of microfluidic biosensors is presented, that considers a random AD process coupled with mass transfer (convection and diffusion) of target substance particles. The deterministic model of sensor response is also reviewed. We perform the analysis of the mass transfer influence on the kinetics and the steady-state value of the response calculated according to the two models (deterministic and stochastic). The results are presented for the sensors with different micro/nanoscale active surfaces. The comparison of the responses obtained by using the two models can be utilized to distinguish the cases in which the application of the deterministic model is justified from those in which the stochastic model is necessary. The presented findings enable more accurate interpretation of measurement results obtained by using micro/nanobiosensors.
Keywords:
adsorption / biological system modeling / biological techniques / bioMEMS / biosensors / fluidic reaction chamber / mass transfer / mathematical modelling / microbiosensors / microfluidic biosensors / microfluidics / microscale active surfaces / microsensors / nanobiosensors / nanobiotechnology / nanoscale active surfaces / nanosensors / patient diagnosis / random adsorption-desorption process / sensor response / steady-state value / stochastic model / stochastic processes / stochastic time response / target substance particles / time factors
Source:
2017 IEEE 30th International Conference on Microelectronics (MIEL), 2017, 127-130
Publisher:
  • IEEE
Funding / projects:
  • Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection (RS-32008)
  • Serbian Academy of Sciences and Arts, Project F-150

DOI: 10.1109/MIEL.2017.8190084

ISBN: 978-1-5386-2563-7

ISSN: 2159-1679

Scopus: 2-s2.0-85043596742
[ Google Scholar ]
1
Handle
https://hdl.handle.net/21.15107/rcub_dais_3684
URI
https://dais.sanu.ac.rs/123456789/3684
Collections
  • Општа колекција САНУ / General collection of SASA
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Jokić, Ivana
AU  - Đurić, Zoran G.
AU  - Radulović, Katarina
AU  - Frantlović, Miloš
PY  - 2017
UR  - https://dais.sanu.ac.rs/123456789/3684
AB  - An approximate model for efficient analysis of stochastic time response of microfluidic biosensors is presented, that considers a random AD process coupled with mass transfer (convection and diffusion) of target substance particles. The deterministic model of sensor response is also reviewed. We perform the analysis of the mass transfer influence on the kinetics and the steady-state value of the response calculated according to the two models (deterministic and stochastic). The results are presented for the sensors with different micro/nanoscale active surfaces. The comparison of the responses obtained by using the two models can be utilized to distinguish the cases in which the application of the deterministic model is justified from those in which the stochastic model is necessary. The presented findings enable more accurate interpretation of measurement results obtained by using micro/nanobiosensors.
PB  - IEEE
C3  - 2017 IEEE 30th International Conference on Microelectronics (MIEL)
T1  - Stochastic time response of adsorption-based micro/nanobiosensors with a fluidic reaction chamber: The influence of mass transfer
SP  - 127
EP  - 130
DO  - 10.1109/MIEL.2017.8190084
UR  - https://hdl.handle.net/21.15107/rcub_dais_3684
ER  - 
@conference{
author = "Jokić, Ivana and Đurić, Zoran G. and Radulović, Katarina and Frantlović, Miloš",
year = "2017",
abstract = "An approximate model for efficient analysis of stochastic time response of microfluidic biosensors is presented, that considers a random AD process coupled with mass transfer (convection and diffusion) of target substance particles. The deterministic model of sensor response is also reviewed. We perform the analysis of the mass transfer influence on the kinetics and the steady-state value of the response calculated according to the two models (deterministic and stochastic). The results are presented for the sensors with different micro/nanoscale active surfaces. The comparison of the responses obtained by using the two models can be utilized to distinguish the cases in which the application of the deterministic model is justified from those in which the stochastic model is necessary. The presented findings enable more accurate interpretation of measurement results obtained by using micro/nanobiosensors.",
publisher = "IEEE",
journal = "2017 IEEE 30th International Conference on Microelectronics (MIEL)",
title = "Stochastic time response of adsorption-based micro/nanobiosensors with a fluidic reaction chamber: The influence of mass transfer",
pages = "127-130",
doi = "10.1109/MIEL.2017.8190084",
url = "https://hdl.handle.net/21.15107/rcub_dais_3684"
}
Jokić, I., Đurić, Z. G., Radulović, K.,& Frantlović, M.. (2017). Stochastic time response of adsorption-based micro/nanobiosensors with a fluidic reaction chamber: The influence of mass transfer. in 2017 IEEE 30th International Conference on Microelectronics (MIEL)
IEEE., 127-130.
https://doi.org/10.1109/MIEL.2017.8190084
https://hdl.handle.net/21.15107/rcub_dais_3684
Jokić I, Đurić ZG, Radulović K, Frantlović M. Stochastic time response of adsorption-based micro/nanobiosensors with a fluidic reaction chamber: The influence of mass transfer. in 2017 IEEE 30th International Conference on Microelectronics (MIEL). 2017;:127-130.
doi:10.1109/MIEL.2017.8190084
https://hdl.handle.net/21.15107/rcub_dais_3684 .
Jokić, Ivana, Đurić, Zoran G., Radulović, Katarina, Frantlović, Miloš, "Stochastic time response of adsorption-based micro/nanobiosensors with a fluidic reaction chamber: The influence of mass transfer" in 2017 IEEE 30th International Conference on Microelectronics (MIEL) (2017):127-130,
https://doi.org/10.1109/MIEL.2017.8190084 .,
https://hdl.handle.net/21.15107/rcub_dais_3684 .

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