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One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling

Thumbnail
2018
Dinic-YUCOMAT-2018.pdf (1.303Mb)
Аутори
Dinić, Ivana
Vuković, Marina
Mančić, Lidija
Krmpot, Aleksandar
Milošević, Olivera
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документу
Апстракт
In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the p...articles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.

Кључне речи:
up-converting nanoparticles / NaYF4:Yb,Er / cell labelling / nanoparticles
Извор:
Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018, 2018, 116-116
Издавач:
  • Belgrade : Materials Research Society of Serbia
Пројекти:
  • Рационални дизајн и синтеза биолошки активних и координационих једињења и функционалних материјала, релевантних у (био)нанотехнологији (RS-172035)

ISBN: 978-86-919111-3-3

[ Google Scholar ]
URI
http://dais.sanu.ac.rs/123456789/3635
Колекције
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
Институција
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Dinić, Ivana
AU  - Vuković, Marina
AU  - Mančić, Lidija
AU  - Krmpot, Aleksandar
AU  - Milošević, Olivera
PY  - 2018
UR  - http://dais.sanu.ac.rs/123456789/3635
AB  - In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the particles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.
PB  - Belgrade : Materials Research Society of Serbia
C3  - Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018
T1  - One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling
SP  - 116
EP  - 116
ER  - 
@conference{
author = "Dinić, Ivana and Vuković, Marina and Mančić, Lidija and Krmpot, Aleksandar and Milošević, Olivera",
year = "2018",
url = "http://dais.sanu.ac.rs/123456789/3635",
abstract = "In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the particles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018",
title = "One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling",
pages = "116-116"
}
Dinić I, Vuković M, Mančić L, Krmpot A, Milošević O. One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling. Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018. 2018;:116-116
Dinić, I., Vuković, M., Mančić, L., Krmpot, A.,& Milošević, O. (2018). One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling.
Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018Belgrade : Materials Research Society of Serbia., 116-116.
Dinić Ivana, Vuković Marina, Mančić Lidija, Krmpot Aleksandar, Milošević Olivera, "One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling" (2018):116-116

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