In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the p...articles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.
TY - CONF
AU - Dinić, Ivana
AU - Vuković, Marina
AU - Mančić, Lidija
AU - Krmpot, Aleksandar
AU - Milošević, Olivera
PY - 2018
UR - https://dais.sanu.ac.rs/123456789/3635
AB - In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the particles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.
PB - Belgrade : Materials Research Society of Serbia
C3 - Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018
T1 - One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling
SP - 116
EP - 116
UR - https://hdl.handle.net/21.15107/rcub_dais_3635
ER -
@conference{
author = "Dinić, Ivana and Vuković, Marina and Mančić, Lidija and Krmpot, Aleksandar and Milošević, Olivera",
year = "2018",
abstract = "In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the particles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018",
title = "One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling",
pages = "116-116",
url = "https://hdl.handle.net/21.15107/rcub_dais_3635"
}
Dinić, I., Vuković, M., Mančić, L., Krmpot, A.,& Milošević, O.. (2018). One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling. in Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018
Belgrade : Materials Research Society of Serbia., 116-116.
https://hdl.handle.net/21.15107/rcub_dais_3635
Dinić I, Vuković M, Mančić L, Krmpot A, Milošević O. One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling. in Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018. 2018;:116-116.
https://hdl.handle.net/21.15107/rcub_dais_3635 .
Dinić, Ivana, Vuković, Marina, Mančić, Lidija, Krmpot, Aleksandar, Milošević, Olivera, "One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling" in Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018 (2018):116-116,
https://hdl.handle.net/21.15107/rcub_dais_3635 .
