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Biodegradable composites based on nanocrystalline calcium phosphate and bioresorbable polymers

Authorized Users Only
2008
Authors
Ignjatović, Nenad
Uskoković, Dragan
Article (Published version)
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Abstract
Nanocrystalline calcium phosphates (NC CP) are suitable for the synthesis of CP/bioresorbable polymer composite biomaterials for the application in bone engineering. There are different forms of NC CP/ bioresorbable polymers composite biomaterials. Calcium phosphate was synthesised in highly NC form. A NC calcium phosphate/ poly-DL-lactide-co-glycolide (CP/DLPLG) composite biomaterial in filler forms was synthesised in the shape of spherical granules (150-200 μm in diameter) and nanoparticles (30-40 nm in diameter). Each CP granule or nanoparticle was coated with amorphous DLPLG polymer. Using NC and nanosized CP/DLPLG composite materials, an injectable composite biomaterial was prepared. By hot pressing of highly porous NC CP/ bioresorbable polymer composite biomaterials at the polymer's melting temperature, blocks were obtained with relatively uniform distribution of phases. Designing of the properties of CP/bioresorbable polymers composite biomaterial block was provided by combining... high pressure, temperature and time. © 2008 Institute of Materials, Minerals and Mining.

Keywords:
composite biomaterials / injectable paste / nanocrystalline calcium phosphate / resorbable polymer
Source:
Advances in Applied Ceramics, 2008, 107, 3, 142-147
Publisher:
  • Taylor & Francis
Funding / projects:
  • Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (RS-142006)

DOI: 10.1179/174367608X263421

ISSN: 1743-6753 (Print); 1743-6761 (Online)

WoS: 000258137000004

Scopus: 2-s2.0-50349087679
[ Google Scholar ]
11
9
Handle
https://hdl.handle.net/21.15107/rcub_dais_3581
URI
https://dais.sanu.ac.rs/123456789/3581
Collections
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2008
UR  - https://dais.sanu.ac.rs/123456789/3581
AB  - Nanocrystalline calcium phosphates (NC CP) are suitable for the synthesis of CP/bioresorbable polymer composite biomaterials for the application in bone engineering. There are different forms of NC CP/ bioresorbable polymers composite biomaterials. Calcium phosphate was synthesised in highly NC form. A NC calcium phosphate/ poly-DL-lactide-co-glycolide (CP/DLPLG) composite biomaterial in filler forms was synthesised in the shape of spherical granules (150-200 μm in diameter) and nanoparticles (30-40 nm in diameter). Each CP granule or nanoparticle was coated with amorphous DLPLG polymer. Using NC and nanosized CP/DLPLG composite materials, an injectable composite biomaterial was prepared. By hot pressing of highly porous NC CP/ bioresorbable polymer composite biomaterials at the polymer's melting temperature, blocks were obtained with relatively uniform distribution of phases. Designing of the properties of CP/bioresorbable polymers composite biomaterial block was provided by combining high pressure, temperature and time. © 2008 Institute of Materials, Minerals and Mining.
PB  - Taylor & Francis
T2  - Advances in Applied Ceramics
T1  - Biodegradable composites based on nanocrystalline calcium phosphate and bioresorbable polymers
SP  - 142
EP  - 147
VL  - 107
IS  - 3
DO  - 10.1179/174367608X263421
UR  - https://hdl.handle.net/21.15107/rcub_dais_3581
ER  - 
@article{
author = "Ignjatović, Nenad and Uskoković, Dragan",
year = "2008",
abstract = "Nanocrystalline calcium phosphates (NC CP) are suitable for the synthesis of CP/bioresorbable polymer composite biomaterials for the application in bone engineering. There are different forms of NC CP/ bioresorbable polymers composite biomaterials. Calcium phosphate was synthesised in highly NC form. A NC calcium phosphate/ poly-DL-lactide-co-glycolide (CP/DLPLG) composite biomaterial in filler forms was synthesised in the shape of spherical granules (150-200 μm in diameter) and nanoparticles (30-40 nm in diameter). Each CP granule or nanoparticle was coated with amorphous DLPLG polymer. Using NC and nanosized CP/DLPLG composite materials, an injectable composite biomaterial was prepared. By hot pressing of highly porous NC CP/ bioresorbable polymer composite biomaterials at the polymer's melting temperature, blocks were obtained with relatively uniform distribution of phases. Designing of the properties of CP/bioresorbable polymers composite biomaterial block was provided by combining high pressure, temperature and time. © 2008 Institute of Materials, Minerals and Mining.",
publisher = "Taylor & Francis",
journal = "Advances in Applied Ceramics",
title = "Biodegradable composites based on nanocrystalline calcium phosphate and bioresorbable polymers",
pages = "142-147",
volume = "107",
number = "3",
doi = "10.1179/174367608X263421",
url = "https://hdl.handle.net/21.15107/rcub_dais_3581"
}
Ignjatović, N.,& Uskoković, D.. (2008). Biodegradable composites based on nanocrystalline calcium phosphate and bioresorbable polymers. in Advances in Applied Ceramics
Taylor & Francis., 107(3), 142-147.
https://doi.org/10.1179/174367608X263421
https://hdl.handle.net/21.15107/rcub_dais_3581
Ignjatović N, Uskoković D. Biodegradable composites based on nanocrystalline calcium phosphate and bioresorbable polymers. in Advances in Applied Ceramics. 2008;107(3):142-147.
doi:10.1179/174367608X263421
https://hdl.handle.net/21.15107/rcub_dais_3581 .
Ignjatović, Nenad, Uskoković, Dragan, "Biodegradable composites based on nanocrystalline calcium phosphate and bioresorbable polymers" in Advances in Applied Ceramics, 107, no. 3 (2008):142-147,
https://doi.org/10.1179/174367608X263421 .,
https://hdl.handle.net/21.15107/rcub_dais_3581 .

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