DAIS - Digital Archive of the Serbian Academy of Sciences and Arts
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   DAIS
  • Институт техничких наука САНУ / Institute of Technical Sciences of SASA
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
  • View Item
  •   DAIS
  • Институт техничких наука САНУ / Institute of Technical Sciences of SASA
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles

Thumbnail
2010
Ajdukovic_YUCOMAT2010_167.pdf (238.8Kb)
Authors
Ajduković, Zorica
Petrović, Milica B.
Milićević, Jelena
Đorđević, N.
Ignjatović, Nenad
Uskoković, Dragan
Savić, Vojin
Conference object (Published version)
Metadata
Show full item record
Abstract
One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineral...ized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.

Keywords:
osteoporosis / magnetic nanomaterials / biocomposites / hydroxyapatite
Source:
Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010, 2010, 167-167
Publisher:
  • Belgrade : Institute of Technical Sciences of SASA
Funding / projects:
  • Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (RS-142006)
  • Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija (RS-145068)

ISBN: 9788680321189

[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_dais_3552
URI
https://dais.sanu.ac.rs/123456789/3552
Collections
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin
PY  - 2010
UR  - https://dais.sanu.ac.rs/123456789/3552
AB  - One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 167
EP  - 167
UR  - https://hdl.handle.net/21.15107/rcub_dais_3552
ER  - 
@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, N. and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin",
year = "2010",
abstract = "One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "167-167",
url = "https://hdl.handle.net/21.15107/rcub_dais_3552"
}
Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V.. (2010). Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 167-167.
https://hdl.handle.net/21.15107/rcub_dais_3552
Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić V. Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:167-167.
https://hdl.handle.net/21.15107/rcub_dais_3552 .
Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, N., Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin, "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):167-167,
https://hdl.handle.net/21.15107/rcub_dais_3552 .

DSpace software copyright © 2002-2015  DuraSpace
About DAIS - Digital Archive of the Serbian Academy of Sciences and Arts | Send Feedback

re3dataOpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About DAIS - Digital Archive of the Serbian Academy of Sciences and Arts | Send Feedback

re3dataOpenAIRERCUB