Local drug delivery for the treatment of infectious bone tissue diseases is a high importance topic in the field of biomedicine for a last two decades. [1] In general, some of the main problems related to controlled drug delivery of antibiotics are: (i) high initial burst effect with toxic outcome and (ii) low concentration of released drug during extended period of time with possibility for development of resistant spaces.[2] There are some examples suggesting that core-shell particles applied as carriers of drug are able to provide high control over the process of drug release and to prevent burst effect.[3,4] Therefore, the main goal of our work is to design material which will be able to provide these characteristics.
Source:
European Cells and Materials, 2010, 20, SUPPL. 3, 266-266
Publisher:
Davos: AO Research Institute Davos
Projects:
Bilateral cooperation program between the Republic of Serbia and the Republic of Slovenia
Note:
3rd International NanoBio Conference 2010, ETH Zurich, Switzerland, August 24-27 2010
TY - CONF
AU - Vukomanović, Marija
AU - Škapin, Srečo Davor
AU - Šarčev, Ivan
AU - Ignjatović, Nenad
AU - Uskoković, Dragan
PY - 2010
UR - http://dais.sanu.ac.rs/123456789/3436
AB - Local drug delivery for the treatment of infectious bone tissue diseases is a high importance topic in the field of biomedicine for a last two decades. [1] In general, some of the main problems related to controlled drug delivery of antibiotics are: (i) high initial burst effect with toxic outcome and (ii) low concentration of released drug during extended period of time with possibility for development of resistant spaces.[2] There are some examples suggesting that core-shell particles applied as carriers of drug are able to provide high control over the process of drug release and to prevent burst effect.[3,4] Therefore, the main goal of our work is to design material which will be able to provide these characteristics.
PB - Davos: AO Research Institute Davos
C3 - European Cells and Materials
C3 - European Cells and Materials
T1 - Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics
SP - 266
EP - 266
VL - 20
IS - SUPPL. 3
ER -
@conference{
author = "Vukomanović, Marija and Škapin, Srečo Davor and Šarčev, Ivan and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
url = "http://dais.sanu.ac.rs/123456789/3436",
abstract = "Local drug delivery for the treatment of infectious bone tissue diseases is a high importance topic in the field of biomedicine for a last two decades. [1] In general, some of the main problems related to controlled drug delivery of antibiotics are: (i) high initial burst effect with toxic outcome and (ii) low concentration of released drug during extended period of time with possibility for development of resistant spaces.[2] There are some examples suggesting that core-shell particles applied as carriers of drug are able to provide high control over the process of drug release and to prevent burst effect.[3,4] Therefore, the main goal of our work is to design material which will be able to provide these characteristics.",
publisher = "Davos: AO Research Institute Davos",
journal = "European Cells and Materials, European Cells and Materials",
title = "Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics",
pages = "266-266",
volume = "20",
number = "SUPPL. 3"
}
Vukomanović M, Škapin SD, Šarčev I, Ignjatović N, Uskoković D. Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics. European Cells and Materials. 2010;20(SUPPL. 3):266-266
Vukomanović, M., Škapin, S. D., Šarčev, I., Ignjatović, N.,& Uskoković, D. (2010). Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics.
European Cells and MaterialsDavos: AO Research Institute Davos., 20(SUPPL. 3), 266-266.
Vukomanović Marija, Škapin Srečo Davor, Šarčev Ivan, Ignjatović Nenad, Uskoković Dragan, "Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics" 20, no. SUPPL. 3 (2010):266-266
