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Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics

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2010
EurCellTiss2010-Vukomanovic.pdf (1018.Kb)
Authors
Vukomanović, Marija
Škapin, Srečo Davor
Šarčev, Ivan
Ignjatović, Nenad
Uskoković, Dragan
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Abstract
Local drug delivery for the treatment of infectious bone tissue diseases is a high importance topic in the field of biomedicine for a last two decades. [1] In general, some of the main problems related to controlled drug delivery of antibiotics are: (i) high initial burst effect with toxic outcome and (ii) low concentration of released drug during extended period of time with possibility for development of resistant spaces.[2] There are some examples suggesting that core-shell particles applied as carriers of drug are able to provide high control over the process of drug release and to prevent burst effect.[3,4] Therefore, the main goal of our work is to design material which will be able to provide these characteristics.
Source:
European Cells and Materials, 2010, 20, SUPPL. 3, 266-266
Publisher:
  • Davos: AO Research Institute Davos
Funding / projects:
  • Bilateral cooperation program between the Republic of Serbia and the Republic of Slovenia
Note:
  • 3rd International NanoBio Conference 2010, ETH Zurich, Switzerland, August 24-27 2010

ISSN: 1473-2262

Scopus: 2-s2.0-84860906069
[ Google Scholar ]
1
Handle
https://hdl.handle.net/21.15107/rcub_dais_3436
URI
https://dais.sanu.ac.rs/123456789/3436
Collections
  • ИТН САНУ - Општа колекција / ITS SASA - General collection
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CONF
AU  - Vukomanović, Marija
AU  - Škapin, Srečo Davor
AU  - Šarčev, Ivan
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2010
UR  - https://dais.sanu.ac.rs/123456789/3436
AB  - Local drug delivery for the treatment of infectious bone tissue diseases is a high importance topic in the field of biomedicine for a last two decades. [1] In general, some of the main problems related to controlled drug delivery of antibiotics are: (i) high initial burst effect with toxic outcome and (ii) low concentration of released drug during extended period of time with possibility for development of resistant spaces.[2] There are some examples suggesting that core-shell particles applied as carriers of drug are able to provide high control over the process of drug release and to prevent burst effect.[3,4] Therefore, the main goal of our work is to design material which will be able to provide these characteristics.
PB  - Davos: AO Research Institute Davos
C3  - European Cells and Materials
C3  - European Cells and Materials
T1  - Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics
SP  - 266
EP  - 266
VL  - 20
IS  - SUPPL. 3
UR  - https://hdl.handle.net/21.15107/rcub_dais_3436
ER  - 
@conference{
author = "Vukomanović, Marija and Škapin, Srečo Davor and Šarčev, Ivan and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
abstract = "Local drug delivery for the treatment of infectious bone tissue diseases is a high importance topic in the field of biomedicine for a last two decades. [1] In general, some of the main problems related to controlled drug delivery of antibiotics are: (i) high initial burst effect with toxic outcome and (ii) low concentration of released drug during extended period of time with possibility for development of resistant spaces.[2] There are some examples suggesting that core-shell particles applied as carriers of drug are able to provide high control over the process of drug release and to prevent burst effect.[3,4] Therefore, the main goal of our work is to design material which will be able to provide these characteristics.",
publisher = "Davos: AO Research Institute Davos",
journal = "European Cells and Materials, European Cells and Materials",
title = "Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics",
pages = "266-266",
volume = "20",
number = "SUPPL. 3",
url = "https://hdl.handle.net/21.15107/rcub_dais_3436"
}
Vukomanović, M., Škapin, S. D., Šarčev, I., Ignjatović, N.,& Uskoković, D.. (2010). Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics. in European Cells and Materials
Davos: AO Research Institute Davos., 20(SUPPL. 3), 266-266.
https://hdl.handle.net/21.15107/rcub_dais_3436
Vukomanović M, Škapin SD, Šarčev I, Ignjatović N, Uskoković D. Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics. in European Cells and Materials. 2010;20(SUPPL. 3):266-266.
https://hdl.handle.net/21.15107/rcub_dais_3436 .
Vukomanović, Marija, Škapin, Srečo Davor, Šarčev, Ivan, Ignjatović, Nenad, Uskoković, Dragan, "Perspectives of Novel Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics" in European Cells and Materials, 20, no. SUPPL. 3 (2010):266-266,
https://hdl.handle.net/21.15107/rcub_dais_3436 .

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