Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics
Authorized Users Only
2004
Authors
Ignjatović, Nenad
Suljovrujić, Edin H.

Budinski-Simendić, Jaroslava K.

Krakovsky, Ivan
Uskoković, Dragan

Article (Published version)

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Show full item recordAbstract
Hydroxyapatite/poly-L-lactide (HAp/PLLA) is a ceramic/polymer composite, whose application as a resorbable biomaterial for the substitution and repair of hard bone tissue is widely promising in orthopedic, oral, maxillofacial, and reconstructive surgery. Hot processing is a necessary step for obtaining HAp/PLLA composite blocks with mechanical properties similar to those of bones. In this article, the changes in structure and physicochemical properties of HAp/PLLA composite, hot pressed for different pressing times (5, 15, 30, 45, and 60 min), were studied. Because the morphology of HAp/PLLA composite biomaterial is very sensitive to this procedure, its surface microstructure was analyzed by scanning electron microscopy (SEM) coupled with an energy-dispersive X-ray (EDX) detector system. Structural changes occurring in the material, mostly changes in crystallinity of PLLA, were studied by wide-angle X-ray structural analyses (WAXS) and infrared (FTIR) spectroscopy. Using differential s...canning calorimetry (DSC), thermogravimetric analysis (TGA), and gel permeation chromatography (GPC), the influence of hot pressing on the properties, crystallization kinetics, and decomposition of HAp/PLLA composite biomaterial was analyzed. (C) 2004 Wiley Periodicals, Inc.
Keywords:
composite biomaterials / hydroxyapatite / poly-L-lactide / hot pressing / crystallinity / mechanical propertiesSource:
Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 2004, 71B, 2, 284-294Funding / projects:
- Ministry of Science, Technology and Development of the Republic of Serbia. Grant Number: 1431
DOI: 10.1002/jbm.b.30093
ISSN: 1552-4973 (print); 1552-4981 (electronic)
PubMed: 15386398
WoS: 000224846700009
Scopus: 2-s2.0-7744235031
Institution/Community
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - JOUR AU - Ignjatović, Nenad AU - Suljovrujić, Edin H. AU - Budinski-Simendić, Jaroslava K. AU - Krakovsky, Ivan AU - Uskoković, Dragan PY - 2004 UR - https://dais.sanu.ac.rs/123456789/2744 AB - Hydroxyapatite/poly-L-lactide (HAp/PLLA) is a ceramic/polymer composite, whose application as a resorbable biomaterial for the substitution and repair of hard bone tissue is widely promising in orthopedic, oral, maxillofacial, and reconstructive surgery. Hot processing is a necessary step for obtaining HAp/PLLA composite blocks with mechanical properties similar to those of bones. In this article, the changes in structure and physicochemical properties of HAp/PLLA composite, hot pressed for different pressing times (5, 15, 30, 45, and 60 min), were studied. Because the morphology of HAp/PLLA composite biomaterial is very sensitive to this procedure, its surface microstructure was analyzed by scanning electron microscopy (SEM) coupled with an energy-dispersive X-ray (EDX) detector system. Structural changes occurring in the material, mostly changes in crystallinity of PLLA, were studied by wide-angle X-ray structural analyses (WAXS) and infrared (FTIR) spectroscopy. Using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and gel permeation chromatography (GPC), the influence of hot pressing on the properties, crystallization kinetics, and decomposition of HAp/PLLA composite biomaterial was analyzed. (C) 2004 Wiley Periodicals, Inc. T2 - Journal of Biomedical Materials Research. Part B: Applied Biomaterials T1 - Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics SP - 284 EP - 294 VL - 71B IS - 2 DO - 10.1002/jbm.b.30093 UR - https://hdl.handle.net/21.15107/rcub_dais_2744 ER -
@article{ author = "Ignjatović, Nenad and Suljovrujić, Edin H. and Budinski-Simendić, Jaroslava K. and Krakovsky, Ivan and Uskoković, Dragan", year = "2004", abstract = "Hydroxyapatite/poly-L-lactide (HAp/PLLA) is a ceramic/polymer composite, whose application as a resorbable biomaterial for the substitution and repair of hard bone tissue is widely promising in orthopedic, oral, maxillofacial, and reconstructive surgery. Hot processing is a necessary step for obtaining HAp/PLLA composite blocks with mechanical properties similar to those of bones. In this article, the changes in structure and physicochemical properties of HAp/PLLA composite, hot pressed for different pressing times (5, 15, 30, 45, and 60 min), were studied. Because the morphology of HAp/PLLA composite biomaterial is very sensitive to this procedure, its surface microstructure was analyzed by scanning electron microscopy (SEM) coupled with an energy-dispersive X-ray (EDX) detector system. Structural changes occurring in the material, mostly changes in crystallinity of PLLA, were studied by wide-angle X-ray structural analyses (WAXS) and infrared (FTIR) spectroscopy. Using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and gel permeation chromatography (GPC), the influence of hot pressing on the properties, crystallization kinetics, and decomposition of HAp/PLLA composite biomaterial was analyzed. (C) 2004 Wiley Periodicals, Inc.", journal = "Journal of Biomedical Materials Research. Part B: Applied Biomaterials", title = "Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics", pages = "284-294", volume = "71B", number = "2", doi = "10.1002/jbm.b.30093", url = "https://hdl.handle.net/21.15107/rcub_dais_2744" }
Ignjatović, N., Suljovrujić, E. H., Budinski-Simendić, J. K., Krakovsky, I.,& Uskoković, D.. (2004). Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics. in Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 71B(2), 284-294. https://doi.org/10.1002/jbm.b.30093 https://hdl.handle.net/21.15107/rcub_dais_2744
Ignjatović N, Suljovrujić EH, Budinski-Simendić JK, Krakovsky I, Uskoković D. Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics. in Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 2004;71B(2):284-294. doi:10.1002/jbm.b.30093 https://hdl.handle.net/21.15107/rcub_dais_2744 .
Ignjatović, Nenad, Suljovrujić, Edin H., Budinski-Simendić, Jaroslava K., Krakovsky, Ivan, Uskoković, Dragan, "Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics" in Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 71B, no. 2 (2004):284-294, https://doi.org/10.1002/jbm.b.30093 ., https://hdl.handle.net/21.15107/rcub_dais_2744 .