DAIS - Digital Archive of the Serbian Academy of Sciences and Arts
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrilic)
    • Serbian (Latin)
  • Login
View Item 
  •   DAIS
  • Институт техничких наука САНУ / Institute of Technical Sciences of SASA
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
  • View Item
  •   DAIS
  • Институт техничких наука САНУ / Institute of Technical Sciences of SASA
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Assembly of Polymers/Metal Nanoparticles and their Applications as Medical Devices

Authorized Users Only
2014
Authors
Stevanović, Magdalena
Book part (Published version)
Metadata
Show full item record
Abstract
Metallic nanoparticles have attracted much attention and have found applications in diff erent fi elds such as medicine, pharmacy, controlled drug delivery, optics, electronics, and other areas. Among the most promising nanomaterials with antibacterial and antiviral properties are metallic nanoparticles (silver, gold, platinum, etc), which exhibit increased chemical activity due to their large surface to volume ratios, crystallographic surface structure and unique size-dependent optical, electrical and magnetic properties. However, it has been reported that bare metallic nanoparticles can be toxic. Th is supports the concept that this toxicity is associated to the presence of the bare metallic nanoparticle surface, while particles protected by an organic layer, i.e. polymer, are much more biocompatible, and thereby less toxic. Unrelated to the bare metallic surface, several recent studies indicate that, at a cellular level, metal nanoparticles interact with biological molecules within ...mammalian cells and can interfere with the antioxidant defense mechanism leading to the generation of reactive oxygen species (ROS). Increase of ROS levels may result in significant damage to cell structures known as oxidative stress. This review article reports on obtaining metallic nanoparticles with special emphasis on obtaining silver nanoparticles, their incorporation within various polymer materials, physiochemical and biological properties of such obtained systems as well as about their application as medical devices.

Keywords:
metal nanoparticles / polymers / silver nanoparticles / medical devices
Source:
Advanced Biomaterials and Biodevices, 2014, 343-366
Publisher:
  • Hoboken, NJ : John Wiley & Sons
Projects:
  • Molecular designing of nanoparticles with controlled morphological and physicochemical characteristics and functional materials based on them (RS-45004)

ISBN: 9781118773635 (Print)

[ Google Scholar ]
URI
http://dais.sanu.ac.rs/123456789/15429
Collections
  • ITN SANU - Opšta kolekcija / ITS SASA - General collection
Institution
Институт техничких наука САНУ / Institute of Technical Sciences of SASA
TY  - CHAP
AU  - Stevanović, Magdalena
PY  - 2014
UR  - http://dais.sanu.ac.rs/123456789/15429
AB  - Metallic nanoparticles have attracted much attention and have found applications in diff erent fi elds such as medicine, pharmacy, controlled drug delivery, optics, electronics, and other areas. Among the most promising nanomaterials with antibacterial and antiviral properties are metallic nanoparticles (silver, gold, platinum, etc), which exhibit increased chemical activity due to their large surface to volume ratios, crystallographic surface structure and unique size-dependent optical, electrical and magnetic properties. However, it has been reported that bare metallic nanoparticles can be toxic. Th is supports the concept that this toxicity is associated to the presence of the bare metallic nanoparticle surface, while particles protected by an organic layer, i.e. polymer, are much more biocompatible, and thereby less toxic. Unrelated to the bare metallic surface, several recent studies indicate that, at a cellular level, metal nanoparticles interact with biological molecules within mammalian cells and can interfere with the antioxidant defense mechanism leading to the generation of reactive oxygen species (ROS). Increase of ROS levels may result in significant damage to cell structures known as oxidative stress. 
This review article reports on obtaining metallic nanoparticles with special emphasis on obtaining silver nanoparticles, their incorporation within various polymer materials, physiochemical and biological properties of such obtained systems as well as about their application as medical devices.
PB  - Hoboken, NJ : John Wiley & Sons
T2  - Advanced Biomaterials and Biodevices
T1  - Assembly of Polymers/Metal Nanoparticles and their Applications as Medical Devices
SP  - 343
EP  - 366
ER  - 
@article{
author = "Stevanović, Magdalena",
year = "2014",
url = "http://dais.sanu.ac.rs/123456789/15429",
abstract = "Metallic nanoparticles have attracted much attention and have found applications in diff erent fi elds such as medicine, pharmacy, controlled drug delivery, optics, electronics, and other areas. Among the most promising nanomaterials with antibacterial and antiviral properties are metallic nanoparticles (silver, gold, platinum, etc), which exhibit increased chemical activity due to their large surface to volume ratios, crystallographic surface structure and unique size-dependent optical, electrical and magnetic properties. However, it has been reported that bare metallic nanoparticles can be toxic. Th is supports the concept that this toxicity is associated to the presence of the bare metallic nanoparticle surface, while particles protected by an organic layer, i.e. polymer, are much more biocompatible, and thereby less toxic. Unrelated to the bare metallic surface, several recent studies indicate that, at a cellular level, metal nanoparticles interact with biological molecules within mammalian cells and can interfere with the antioxidant defense mechanism leading to the generation of reactive oxygen species (ROS). Increase of ROS levels may result in significant damage to cell structures known as oxidative stress. 
This review article reports on obtaining metallic nanoparticles with special emphasis on obtaining silver nanoparticles, their incorporation within various polymer materials, physiochemical and biological properties of such obtained systems as well as about their application as medical devices.",
publisher = "Hoboken, NJ : John Wiley & Sons",
journal = "Advanced Biomaterials and Biodevices",
title = "Assembly of Polymers/Metal Nanoparticles and their Applications as Medical Devices",
pages = "343-366"
}
Stevanović M. Assembly of Polymers/Metal Nanoparticles and their Applications as Medical Devices. Advanced Biomaterials and Biodevices. 2014;:343-366
,& Stevanović, M. (2014). Assembly of Polymers/Metal Nanoparticles and their Applications as Medical Devices.
Advanced Biomaterials and BiodevicesHoboken, NJ : John Wiley & Sons., null, 343-366. 
Stevanović Magdalena, "Assembly of Polymers/Metal Nanoparticles and their Applications as Medical Devices" null (2014):343-366

DSpace software copyright © 2002-2015  DuraSpace
About DAIS - Digital Archive of the Serbian Academy of Sciences and Arts | Send Feedback

re3dataOpenAIRERCUB
 

 

All of DSpaceInstitutionsAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About DAIS - Digital Archive of the Serbian Academy of Sciences and Arts | Send Feedback

re3dataOpenAIRERCUB