Worldwide pollution with plastic debris represents tremendous environmental issue. Small particles originated from plastic bottles exert various effects in organisms when exposed chronically, while the effects of a single exposure are completely unknown. Thus, to test their potential health impact, male Wistar rats were exposed by oral gavage to a single dose of microplastic particles (MP) derived from polyethylene terephthalate (PET) bottles (1.4, 35 or 125 mg/kg with median diameter of 85 μm). Food and water intakes were monitored, and neurological and clinical tests were conducted. Obtained results point to lower food and water intakes in groups that received two higher MP doses indicating to interference with normal digestion. None of three used MP doses provoked neurological and clinical impairments either due to short-term exposure and/or lack of MP cumulative effect. Overall, presented results indicate that exposure to a single dose of MP can initiate health issues.
TY - CONF
AU - Guševac Stojanović, I.
AU - Drakulić, D.
AU - Todorović, A.
AU - Filipović, Nenad
AU - Stojanović, Zoran
PY - 2021
UR - https://dais.sanu.ac.rs/123456789/13619
AB - Worldwide pollution with plastic debris represents tremendous environmental issue. Small particles originated from plastic bottles exert various effects in organisms when exposed chronically, while the effects of a single exposure are completely unknown. Thus, to test their potential health impact, male Wistar rats were exposed by oral gavage to a single dose of microplastic particles (MP) derived from polyethylene terephthalate (PET) bottles (1.4, 35 or 125 mg/kg with median diameter of 85 μm). Food and water intakes were monitored, and neurological and clinical tests were conducted. Obtained results point to lower food and water intakes in groups that received two higher MP doses indicating to interference with normal digestion. None of three used MP doses provoked neurological and clinical impairments either due to short-term exposure and/or lack of MP cumulative effect. Overall, presented results indicate that exposure to a single dose of MP can initiate health issues.
PB - Belgrade : Society of Physical Chemists of Serbia
C3 - 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Physical Chemistry 2021
T1 - Does exposure to a single dose of microplastic represent a health risk?
SP - 572
EP - 575
UR - https://hdl.handle.net/21.15107/rcub_dais_13619
ER -
@conference{
author = "Guševac Stojanović, I. and Drakulić, D. and Todorović, A. and Filipović, Nenad and Stojanović, Zoran",
year = "2021",
abstract = "Worldwide pollution with plastic debris represents tremendous environmental issue. Small particles originated from plastic bottles exert various effects in organisms when exposed chronically, while the effects of a single exposure are completely unknown. Thus, to test their potential health impact, male Wistar rats were exposed by oral gavage to a single dose of microplastic particles (MP) derived from polyethylene terephthalate (PET) bottles (1.4, 35 or 125 mg/kg with median diameter of 85 μm). Food and water intakes were monitored, and neurological and clinical tests were conducted. Obtained results point to lower food and water intakes in groups that received two higher MP doses indicating to interference with normal digestion. None of three used MP doses provoked neurological and clinical impairments either due to short-term exposure and/or lack of MP cumulative effect. Overall, presented results indicate that exposure to a single dose of MP can initiate health issues.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "15th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Physical Chemistry 2021",
title = "Does exposure to a single dose of microplastic represent a health risk?",
pages = "572-575",
url = "https://hdl.handle.net/21.15107/rcub_dais_13619"
}
Guševac Stojanović, I., Drakulić, D., Todorović, A., Filipović, N.,& Stojanović, Z.. (2021). Does exposure to a single dose of microplastic represent a health risk?. in 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Physical Chemistry 2021
Belgrade : Society of Physical Chemists of Serbia., 572-575.
https://hdl.handle.net/21.15107/rcub_dais_13619
Guševac Stojanović I, Drakulić D, Todorović A, Filipović N, Stojanović Z. Does exposure to a single dose of microplastic represent a health risk?. in 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Physical Chemistry 2021. 2021;:572-575.
https://hdl.handle.net/21.15107/rcub_dais_13619 .
Guševac Stojanović, I., Drakulić, D., Todorović, A., Filipović, Nenad, Stojanović, Zoran, "Does exposure to a single dose of microplastic represent a health risk?" in 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Physical Chemistry 2021 (2021):572-575,
https://hdl.handle.net/21.15107/rcub_dais_13619 .
