The harmful effects that antibiotics may have on human health and increased resistance of microorganisms on antibiotics made pharmaceutical companies look for new alternatives among medicinal and aromatic plants. Recently, as a new strategy to enhance antimicrobial activities of commercial antibiotics, the combination of plant extracts and antibiotics is developing. The aim of the study was to examine the potential synergistic effect of plant extracts with streptomycin. The minimum inhibitory concentration of two extracts obtained from traditional medicinal plants, Alchemilla vulgaris and Frangula alnus, was determined by the microdilution method. The effect of a mixture of extracts and antibiotics was tested with checkerboard assay and confirmed by Time kill assay. The most sensitive strain was E. coli ATCC 25922.
Proceedings / 7th Workshop Specific Methods for Food Safety and Quality, September 22nd, 2021, Belgrade, Serbia, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2021, 2021, 176-179
TY - CONF
AU - Đukanović, S.
AU - Cvetković, S.
AU - Ganić, T.
AU - Nikolić, B.
AU - Tomić, Nina
AU - Kekić, D.
AU - Mitić Ćulafić, D.
PY - 2021
UR - https://dais.sanu.ac.rs/123456789/12380
AB - The harmful effects that antibiotics may have on human health and increased resistance of microorganisms on antibiotics made pharmaceutical companies look for new alternatives among medicinal and aromatic plants. Recently, as a new strategy to enhance antimicrobial activities of commercial antibiotics, the combination of plant extracts and antibiotics is developing. The aim of the study was to examine the potential synergistic effect of plant extracts with streptomycin. The minimum inhibitory concentration of two extracts obtained from traditional medicinal plants, Alchemilla vulgaris and Frangula alnus, was determined by the microdilution method. The effect of a mixture of extracts and antibiotics was tested with checkerboard assay and confirmed by Time kill assay. The most sensitive strain was E. coli ATCC 25922.
PB - Belgrade : Vinča Institute of Nuclear Sciences
C3 - Proceedings / 7th Workshop Specific Methods for Food Safety and Quality, September 22nd, 2021, Belgrade, Serbia, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2021
T1 - Antibacterial activity of aqueous-ethanolic extracts of Alchemilla vulgaris and Frangula alnus combined with streptomycin
SP - 176
EP - 179
UR - https://hdl.handle.net/21.15107/rcub_dais_12380
ER -
@conference{
author = "Đukanović, S. and Cvetković, S. and Ganić, T. and Nikolić, B. and Tomić, Nina and Kekić, D. and Mitić Ćulafić, D.",
year = "2021",
abstract = "The harmful effects that antibiotics may have on human health and increased resistance of microorganisms on antibiotics made pharmaceutical companies look for new alternatives among medicinal and aromatic plants. Recently, as a new strategy to enhance antimicrobial activities of commercial antibiotics, the combination of plant extracts and antibiotics is developing. The aim of the study was to examine the potential synergistic effect of plant extracts with streptomycin. The minimum inhibitory concentration of two extracts obtained from traditional medicinal plants, Alchemilla vulgaris and Frangula alnus, was determined by the microdilution method. The effect of a mixture of extracts and antibiotics was tested with checkerboard assay and confirmed by Time kill assay. The most sensitive strain was E. coli ATCC 25922.",
publisher = "Belgrade : Vinča Institute of Nuclear Sciences",
journal = "Proceedings / 7th Workshop Specific Methods for Food Safety and Quality, September 22nd, 2021, Belgrade, Serbia, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2021",
title = "Antibacterial activity of aqueous-ethanolic extracts of Alchemilla vulgaris and Frangula alnus combined with streptomycin",
pages = "176-179",
url = "https://hdl.handle.net/21.15107/rcub_dais_12380"
}
Đukanović, S., Cvetković, S., Ganić, T., Nikolić, B., Tomić, N., Kekić, D.,& Mitić Ćulafić, D.. (2021). Antibacterial activity of aqueous-ethanolic extracts of Alchemilla vulgaris and Frangula alnus combined with streptomycin. in Proceedings / 7th Workshop Specific Methods for Food Safety and Quality, September 22nd, 2021, Belgrade, Serbia, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2021
Belgrade : Vinča Institute of Nuclear Sciences., 176-179.
https://hdl.handle.net/21.15107/rcub_dais_12380
Đukanović S, Cvetković S, Ganić T, Nikolić B, Tomić N, Kekić D, Mitić Ćulafić D. Antibacterial activity of aqueous-ethanolic extracts of Alchemilla vulgaris and Frangula alnus combined with streptomycin. in Proceedings / 7th Workshop Specific Methods for Food Safety and Quality, September 22nd, 2021, Belgrade, Serbia, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2021. 2021;:176-179.
https://hdl.handle.net/21.15107/rcub_dais_12380 .
Đukanović, S., Cvetković, S., Ganić, T., Nikolić, B., Tomić, Nina, Kekić, D., Mitić Ćulafić, D., "Antibacterial activity of aqueous-ethanolic extracts of Alchemilla vulgaris and Frangula alnus combined with streptomycin" in Proceedings / 7th Workshop Specific Methods for Food Safety and Quality, September 22nd, 2021, Belgrade, Serbia, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2021 (2021):176-179,
https://hdl.handle.net/21.15107/rcub_dais_12380 .
