Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400 000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa.
TY - JOUR
AU - Ignjatović, Nenad
AU - Tomić, Simonida
AU - Dakić, Momčilo
AU - Miljković, Miroslav
AU - Plavšić, Milenko
AU - Uskoković, Dragan
PY - 1999
UR - https://dais.sanu.ac.rs/123456789/10668
AB - Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400 000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa.
PB - Oxford : Elsevier Sci Ltd
T2 - Biomaterials
T1 - Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials
SP - 809
EP - 816
VL - 20
IS - 9
DO - 10.1016/S0142-9612(98)00234-8
UR - https://hdl.handle.net/21.15107/rcub_dais_10668
ER -
@article{
author = "Ignjatović, Nenad and Tomić, Simonida and Dakić, Momčilo and Miljković, Miroslav and Plavšić, Milenko and Uskoković, Dragan",
year = "1999",
abstract = "Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400 000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa.",
publisher = "Oxford : Elsevier Sci Ltd",
journal = "Biomaterials",
title = "Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials",
pages = "809-816",
volume = "20",
number = "9",
doi = "10.1016/S0142-9612(98)00234-8",
url = "https://hdl.handle.net/21.15107/rcub_dais_10668"
}
Ignjatović, N., Tomić, S., Dakić, M., Miljković, M., Plavšić, M.,& Uskoković, D.. (1999). Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials. in Biomaterials
Oxford : Elsevier Sci Ltd., 20(9), 809-816.
https://doi.org/10.1016/S0142-9612(98)00234-8
https://hdl.handle.net/21.15107/rcub_dais_10668
Ignjatović N, Tomić S, Dakić M, Miljković M, Plavšić M, Uskoković D. Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials. in Biomaterials. 1999;20(9):809-816.
doi:10.1016/S0142-9612(98)00234-8
https://hdl.handle.net/21.15107/rcub_dais_10668 .
Ignjatović, Nenad, Tomić, Simonida, Dakić, Momčilo, Miljković, Miroslav, Plavšić, Milenko, Uskoković, Dragan, "Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials" in Biomaterials, 20, no. 9 (1999):809-816,
https://doi.org/10.1016/S0142-9612(98)00234-8 .,
https://hdl.handle.net/21.15107/rcub_dais_10668 .
