Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials
Само за регистроване кориснике
1999
Аутори
Ignjatović, NenadTomić, Simonida
Dakić, Momčilo
Miljković, Miroslav
Plavšić, Milenko
Uskoković, Dragan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400 000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa.
Кључне речи:
calcium hydroxyapatite / poly-L-lactide / biocomposites / designing / microstructure / biocomposites / calcium hydroxyapatite / biomaterials / poly-L-lactide / microstructureИзвор:
Biomaterials, 1999, 20, 9, 809-816Издавач:
- Oxford : Elsevier Sci Ltd
DOI: 10.1016/S0142-9612(98)00234-8
ISSN: 0142-9612
PubMed: 10226707
WoS: 000079761800002
Scopus: 2-s2.0-0010226706
Институција/група
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - JOUR AU - Ignjatović, Nenad AU - Tomić, Simonida AU - Dakić, Momčilo AU - Miljković, Miroslav AU - Plavšić, Milenko AU - Uskoković, Dragan PY - 1999 UR - https://dais.sanu.ac.rs/123456789/10668 AB - Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400 000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa. PB - Oxford : Elsevier Sci Ltd T2 - Biomaterials T1 - Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials SP - 809 EP - 816 VL - 20 IS - 9 DO - 10.1016/S0142-9612(98)00234-8 UR - https://hdl.handle.net/21.15107/rcub_dais_10668 ER -
@article{ author = "Ignjatović, Nenad and Tomić, Simonida and Dakić, Momčilo and Miljković, Miroslav and Plavšić, Milenko and Uskoković, Dragan", year = "1999", abstract = "Calcium hydroxyapatite (HAp) and poly-L-lactide (PLLA) were synthesized chemically. The obtained HAp was of high purity and, after special thermal treatment, of high crystallinity as well. Synthesis of PLLA was performed using L-lactide as a monomer and nontoxic initiator. In this way a polymer of large molar weight (about 400 000) was obtained. The HAp and PLLA obtained were used as constituents of the HAp/PLLA composite biomaterial, a potential material for implants. The composite was obtained by mixing completely dissolved PLLA with granules of HAp. The composite was compacted by cold and hot pressing at pressures of 49.0-490.5 MPa and temperatures of 20-184 degrees C. The material obtained at optimum process parameters had a density of 99.6% and compressive strength of 93.2 MPa.", publisher = "Oxford : Elsevier Sci Ltd", journal = "Biomaterials", title = "Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials", pages = "809-816", volume = "20", number = "9", doi = "10.1016/S0142-9612(98)00234-8", url = "https://hdl.handle.net/21.15107/rcub_dais_10668" }
Ignjatović, N., Tomić, S., Dakić, M., Miljković, M., Plavšić, M.,& Uskoković, D.. (1999). Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials. in Biomaterials Oxford : Elsevier Sci Ltd., 20(9), 809-816. https://doi.org/10.1016/S0142-9612(98)00234-8 https://hdl.handle.net/21.15107/rcub_dais_10668
Ignjatović N, Tomić S, Dakić M, Miljković M, Plavšić M, Uskoković D. Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials. in Biomaterials. 1999;20(9):809-816. doi:10.1016/S0142-9612(98)00234-8 https://hdl.handle.net/21.15107/rcub_dais_10668 .
Ignjatović, Nenad, Tomić, Simonida, Dakić, Momčilo, Miljković, Miroslav, Plavšić, Milenko, Uskoković, Dragan, "Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials" in Biomaterials, 20, no. 9 (1999):809-816, https://doi.org/10.1016/S0142-9612(98)00234-8 ., https://hdl.handle.net/21.15107/rcub_dais_10668 .