Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija

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Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija (en)
Биокомпатибилност и могућности примене биоматеријала на бази хидроксиапатита и биополимера у ткивној репарацији - експериментална и клиничка студија (sr)
Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija (sr_RS)
Authors

Publications

In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite

Ajduković, Zorica; Milićević, Jelena; Petrović, Milica B.; Đorđević, Nadica; Mladenović Antić, Snežana; Kocić, Branislava; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin P.

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Đorđević, Nadica
AU  - Mladenović Antić, Snežana
AU  - Kocić, Branislava
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin P.
PY  - 2010
AB  - Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted calcium hydroxyapatite nanopowders and biphased calciumphosphate/ poli-lactide-co-glicolide. The antimicrobial effects of these substances (powders) against two pathogen bacterial strains- Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were tested by disc diffusion method and quantitative antimicrobial test in liquid medium. It was noted that the inhibition zone of the bacterial cells S. aureus around the sample of the Ca/Co- HAp, was a lot bigger compared to the inhibition zone of bacterial cells E. coli around the sample of the mentioned biomaterial, which means that this material has bigger antimicrobic activity on S. aureus, in relation to E. coli. Quantitative antimicrobial test in liquid medium demonstrate that cobalt-substituted calcium hydroxyapatite samples show viable cells reduction of both tested microorganisms. It may be concluded that nanoparticles of cobalt-substituted calcium hydoxyapatite nano-powders has a satisfactory antimicrobic activity according to the tested bacteria strain.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite
SP  - 18
EP  - 18
UR  - https://hdl.handle.net/21.15107/rcub_dais_3444
ER  - 
@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Đorđević, Nadica and Mladenović Antić, Snežana and Kocić, Branislava and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin P.",
year = "2010",
abstract = "Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted calcium hydroxyapatite nanopowders and biphased calciumphosphate/ poli-lactide-co-glicolide. The antimicrobial effects of these substances (powders) against two pathogen bacterial strains- Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were tested by disc diffusion method and quantitative antimicrobial test in liquid medium. It was noted that the inhibition zone of the bacterial cells S. aureus around the sample of the Ca/Co- HAp, was a lot bigger compared to the inhibition zone of bacterial cells E. coli around the sample of the mentioned biomaterial, which means that this material has bigger antimicrobic activity on S. aureus, in relation to E. coli. Quantitative antimicrobial test in liquid medium demonstrate that cobalt-substituted calcium hydroxyapatite samples show viable cells reduction of both tested microorganisms. It may be concluded that nanoparticles of cobalt-substituted calcium hydoxyapatite nano-powders has a satisfactory antimicrobic activity according to the tested bacteria strain.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite",
pages = "18-18",
url = "https://hdl.handle.net/21.15107/rcub_dais_3444"
}
Ajduković, Z., Milićević, J., Petrović, M. B., Đorđević, N., Mladenović Antić, S., Kocić, B., Ignjatović, N., Uskoković, D.,& Savić, V. P. (2010). In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite.
Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 18-18.
Ajduković Z, Milićević J, Petrović MB, Đorđević N, Mladenović Antić S, Kocić B, Ignjatović N, Uskoković D, Savić VP. In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite. Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:18-18.
Ajduković Zorica, Milićević Jelena, Petrović Milica B., Đorđević Nadica, Mladenović Antić Snežana, Kocić Branislava, Ignjatović Nenad, Uskoković Dragan, Savić Vojin P., "In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite" Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):18-18

Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles

Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Đorđević, N.; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin
PY  - 2010
AB  - One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 167
EP  - 167
UR  - https://hdl.handle.net/21.15107/rcub_dais_3552
ER  - 
@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, N. and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin",
year = "2010",
abstract = "One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "167-167",
url = "https://hdl.handle.net/21.15107/rcub_dais_3552"
}
Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V. (2010). Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles.
Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 167-167.
Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić V. Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:167-167.
Ajduković Zorica, Petrović Milica B., Milićević Jelena, Đorđević N., Ignjatović Nenad, Uskoković Dragan, Savić Vojin, "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):167-167

Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles

Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Đorđević, Nadica; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin P.

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, Nadica
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin P.
PY  - 2010
AB  - This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the mineralized tissues. It can be concluded that Ca/Co-HAp stimulates the regeneration of osteoporotic alveolar bone in tested animals as confirmed by the increased levels of biochemical blood markers and through histochemical analysis. Therefore, it can be concluded that Ca/Co-HAp nanocomposite should be choise material in the osteoconstructive processes in the future.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 19
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_dais_3446
ER  - 
@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, Nadica and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin P.",
year = "2010",
abstract = "This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the mineralized tissues. It can be concluded that Ca/Co-HAp stimulates the regeneration of osteoporotic alveolar bone in tested animals as confirmed by the increased levels of biochemical blood markers and through histochemical analysis. Therefore, it can be concluded that Ca/Co-HAp nanocomposite should be choise material in the osteoconstructive processes in the future.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "19-19",
url = "https://hdl.handle.net/21.15107/rcub_dais_3446"
}
Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V. P. (2010). Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles.
Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 19-19.
Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić VP. Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:19-19.
Ajduković Zorica, Petrović Milica B., Milićević Jelena, Đorđević Nadica, Ignjatović Nenad, Uskoković Dragan, Savić Vojin P., "Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):19-19

Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro

Ajduković, Zorica; Milićević, Jelena; Petrović, Milica B.; Đorđević, N.; Ignjatović, Nenad; Savić, Vojin P.; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Savić, Vojin P.
AU  - Uskoković, Dragan
PY  - 2010
AB  - Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- hydroxyapatite and biphasic calcium phosphate/ poly (lactide-co-glycolide) composite biomaterial. Antimicrobial activity of the samples was tested using dilution method and disk diffusion. The results of antimicrobial tests were obtained by determining the reduction percentage the number of bacteria in physiological solution where bacteria cells were exposed to the samples. It can be concluded that synthesized HAp biomaterials have satisfactory antimicrobial activity against tested bacteria strains.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro
SP  - 168
EP  - 168
UR  - https://hdl.handle.net/21.15107/rcub_dais_3553
ER  - 
@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Đorđević, N. and Ignjatović, Nenad and Savić, Vojin P. and Uskoković, Dragan",
year = "2010",
abstract = "Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- hydroxyapatite and biphasic calcium phosphate/ poly (lactide-co-glycolide) composite biomaterial. Antimicrobial activity of the samples was tested using dilution method and disk diffusion. The results of antimicrobial tests were obtained by determining the reduction percentage the number of bacteria in physiological solution where bacteria cells were exposed to the samples. It can be concluded that synthesized HAp biomaterials have satisfactory antimicrobial activity against tested bacteria strains.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro",
pages = "168-168",
url = "https://hdl.handle.net/21.15107/rcub_dais_3553"
}
Ajduković, Z., Milićević, J., Petrović, M. B., Đorđević, N., Ignjatović, N., Savić, V. P.,& Uskoković, D. (2010). Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro.
Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 168-168.
Ajduković Z, Milićević J, Petrović MB, Đorđević N, Ignjatović N, Savić VP, Uskoković D. Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro. Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:168-168.
Ajduković Zorica, Milićević Jelena, Petrović Milica B., Đorđević N., Ignjatović Nenad, Savić Vojin P., Uskoković Dragan, "Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro" Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):168-168

Size effect of calcium phosphate coated with poly-DL-lactideco-glycolide on healing processes in bone reconstruction

Ignjatović, Nenad; Ajduković, Zorica; Savić, Vojin. P.; Uskoković, Dragan

(Hoboken, NJ : John Wiley & Sons, 2010)

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Ajduković, Zorica
AU  - Savić, Vojin. P.
AU  - Uskoković, Dragan
PY  - 2010
AB  - In this article, synthesis and application of calcium phosphate/poly-DL- lactide-co-glycolide (CP/PLGA) composite biomaterial in particulate form, in which each CP granule/particle is coated with PLGA, are described. Two types of the particulate material having different particle sizes were synthesized: one with an average particle diameter between 150 and 250 μm (micron-sized particles, MPs) and the other with an average particle diameter smaller than 50 nm (nanoparticles, NPs). A comparative in vivo analysis was done by reconstructing defects in osteoporotic alveolar bones using both composites. The material, CP granules/particles covered with polymer, was characterized using X-ray structural analysis, scanning electron microscopy, and atomic force microscopy. Changes in reparatory functions of tissues affected by osteoporosis were examined in mice in vivo, using these two kinds of composite materials, with and without autologous plasma. Having defined the target segment, histomorphometric parameters - bone area fraction, area, and mean density - were determined. The best results in the regeneration and recuperation of alveolar bone damaged by osteoporosis were achieved with the implantation of a mixture of nanoparticulate CP/PLGA composite and autologous plasma. After the implantation of microparticulate CP/PLGA, in the form of granules, mixed with autologous plasma, into an artificial defect in alveolar bone, new bone formation was also observed, although its formation rate was slower. © 2010 Wiley Periodicals, Inc.
PB  - Hoboken, NJ : John Wiley & Sons
T2  - Journal of Biomedical Materials Research - Part B Applied Biomaterials
T1  - Size effect of calcium phosphate coated with poly-DL-lactideco-glycolide on healing processes in bone reconstruction
SP  - 108
EP  - 117
VL  - 94
IS  - 1
DO  - 10.1002/jbm.b.31630
UR  - https://hdl.handle.net/21.15107/rcub_dais_3419
ER  - 
@article{
author = "Ignjatović, Nenad and Ajduković, Zorica and Savić, Vojin. P. and Uskoković, Dragan",
year = "2010",
abstract = "In this article, synthesis and application of calcium phosphate/poly-DL- lactide-co-glycolide (CP/PLGA) composite biomaterial in particulate form, in which each CP granule/particle is coated with PLGA, are described. Two types of the particulate material having different particle sizes were synthesized: one with an average particle diameter between 150 and 250 μm (micron-sized particles, MPs) and the other with an average particle diameter smaller than 50 nm (nanoparticles, NPs). A comparative in vivo analysis was done by reconstructing defects in osteoporotic alveolar bones using both composites. The material, CP granules/particles covered with polymer, was characterized using X-ray structural analysis, scanning electron microscopy, and atomic force microscopy. Changes in reparatory functions of tissues affected by osteoporosis were examined in mice in vivo, using these two kinds of composite materials, with and without autologous plasma. Having defined the target segment, histomorphometric parameters - bone area fraction, area, and mean density - were determined. The best results in the regeneration and recuperation of alveolar bone damaged by osteoporosis were achieved with the implantation of a mixture of nanoparticulate CP/PLGA composite and autologous plasma. After the implantation of microparticulate CP/PLGA, in the form of granules, mixed with autologous plasma, into an artificial defect in alveolar bone, new bone formation was also observed, although its formation rate was slower. © 2010 Wiley Periodicals, Inc.",
publisher = "Hoboken, NJ : John Wiley & Sons",
journal = "Journal of Biomedical Materials Research - Part B Applied Biomaterials",
title = "Size effect of calcium phosphate coated with poly-DL-lactideco-glycolide on healing processes in bone reconstruction",
pages = "108-117",
volume = "94",
number = "1",
doi = "10.1002/jbm.b.31630",
url = "https://hdl.handle.net/21.15107/rcub_dais_3419"
}
Ignjatović, N., Ajduković, Z., Savić, Vojin. P.,& Uskoković, D. (2010). Size effect of calcium phosphate coated with poly-DL-lactideco-glycolide on healing processes in bone reconstruction.
Journal of Biomedical Materials Research - Part B Applied Biomaterials
Hoboken, NJ : John Wiley & Sons., 94(1), 108-117.
https://doi.org/10.1002/jbm.b.31630
Ignjatović N, Ajduković Z, Savić VP, Uskoković D. Size effect of calcium phosphate coated with poly-DL-lactideco-glycolide on healing processes in bone reconstruction. Journal of Biomedical Materials Research - Part B Applied Biomaterials. 2010;94(1):108-117.
doi:10.1002/jbm.b.31630.
Ignjatović Nenad, Ajduković Zorica, Savić Vojin. P., Uskoković Dragan, "Size effect of calcium phosphate coated with poly-DL-lactideco-glycolide on healing processes in bone reconstruction" Journal of Biomedical Materials Research - Part B Applied Biomaterials, 94, no. 1 (2010):108-117,
https://doi.org/10.1002/jbm.b.31630 .
23
22
28

Mineral substances in the bone tissue and blood of patients with osteoporosis

Ajduković, Zorica; Dimić, A.; Stanković, S.; Krunić, N.; Aleksov, L.; Ignjatović, Nenad

(Novi Sad : Društvo lekara Vojvodine Srpskog lekarskog društva, 2009)

TY  - JOUR
AU  - Ajduković, Zorica
AU  - Dimić, A.
AU  - Stanković, S.
AU  - Krunić, N.
AU  - Aleksov, L.
AU  - Ignjatović, Nenad
PY  - 2009
AB  - Osteoporosis is a very common disorder of skeleton, which can be caused by various metabolic disturbances, malnutrition, immobilization, endocrine disorders, bone marrow diseases, connective tissue disorders, and, in some cases, by inappropriate therapy. The aim of this investigation was to evaluate the relationships between the mineral content in the alveolar bone and serum osteoporosis in chosen patients. MATERIAL AND METHODS: The study included an experimental and a control group of patients who were submitted to internal and prosthodontic therapy. The plan of therapy was to extract anticipated parodonthopathic teeth, taking samples of the alveolar bone and its analysis by spectrometry. At the same time the biochemical analyses of the blood were performed. RESULTS: Before the therapy, due to negative remodeling, values of mineral content in decalcified bone tissue and serum were significantly lower than in the control group. After the therapy, the quality of the bone tissue was improved, with increased contents of mineral substances. DISCUSSION AND CONCLUSION: Disorders of mineral metabolism are very important for osteoporosis. This disorder may involve entire skeleton, especially stomatoghnatic complex. Therefore osteoporosis is one of very important illnesses in dentistry, especially in prosthodontics, because of the supporting nature of bone tissue for all types of dental prostheses.
PB  - Novi Sad : Društvo lekara Vojvodine Srpskog lekarskog društva
T2  - Medicinski pregled
T1  - Mineral substances in the bone tissue and blood of patients with osteoporosis
SP  - 402
EP  - 406
VL  - 62
IS  - 9-10
DO  - 10.2298/MPNS0910402A
UR  - https://hdl.handle.net/21.15107/rcub_dais_3475
ER  - 
@article{
author = "Ajduković, Zorica and Dimić, A. and Stanković, S. and Krunić, N. and Aleksov, L. and Ignjatović, Nenad",
year = "2009",
abstract = "Osteoporosis is a very common disorder of skeleton, which can be caused by various metabolic disturbances, malnutrition, immobilization, endocrine disorders, bone marrow diseases, connective tissue disorders, and, in some cases, by inappropriate therapy. The aim of this investigation was to evaluate the relationships between the mineral content in the alveolar bone and serum osteoporosis in chosen patients. MATERIAL AND METHODS: The study included an experimental and a control group of patients who were submitted to internal and prosthodontic therapy. The plan of therapy was to extract anticipated parodonthopathic teeth, taking samples of the alveolar bone and its analysis by spectrometry. At the same time the biochemical analyses of the blood were performed. RESULTS: Before the therapy, due to negative remodeling, values of mineral content in decalcified bone tissue and serum were significantly lower than in the control group. After the therapy, the quality of the bone tissue was improved, with increased contents of mineral substances. DISCUSSION AND CONCLUSION: Disorders of mineral metabolism are very important for osteoporosis. This disorder may involve entire skeleton, especially stomatoghnatic complex. Therefore osteoporosis is one of very important illnesses in dentistry, especially in prosthodontics, because of the supporting nature of bone tissue for all types of dental prostheses.",
publisher = "Novi Sad : Društvo lekara Vojvodine Srpskog lekarskog društva",
journal = "Medicinski pregled",
title = "Mineral substances in the bone tissue and blood of patients with osteoporosis",
pages = "402-406",
volume = "62",
number = "9-10",
doi = "10.2298/MPNS0910402A",
url = "https://hdl.handle.net/21.15107/rcub_dais_3475"
}
Ajduković, Z., Dimić, A., Stanković, S., Krunić, N., Aleksov, L.,& Ignjatović, N. (2009). Mineral substances in the bone tissue and blood of patients with osteoporosis.
Medicinski pregled
Novi Sad : Društvo lekara Vojvodine Srpskog lekarskog društva., 62(9-10), 402-406.
https://doi.org/10.2298/MPNS0910402A
Ajduković Z, Dimić A, Stanković S, Krunić N, Aleksov L, Ignjatović N. Mineral substances in the bone tissue and blood of patients with osteoporosis. Medicinski pregled. 2009;62(9-10):402-406.
doi:10.2298/MPNS0910402A.
Ajduković Zorica, Dimić A., Stanković S., Krunić N., Aleksov L., Ignjatović Nenad, "Mineral substances in the bone tissue and blood of patients with osteoporosis" Medicinski pregled, 62, no. 9-10 (2009):402-406,
https://doi.org/10.2298/MPNS0910402A .
2

Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles

Ajduković, Zorica; Ignjatović, Nenad; Stojanović, Zoran S.; Kaličanin, Biljana; Savić, Vojin; Petrović, S. M.; Petrović, B. M.; Milićević, Jelena; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2009)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Stojanović, Zoran S.
AU  - Kaličanin, Biljana
AU  - Savić, Vojin
AU  - Petrović, S. M.
AU  - Petrović, B. M.
AU  - Milićević, Jelena
AU  - Uskoković, Dragan
PY  - 2009
AB  - In this study nanocomposite was used for reconstruction of alveolar bone defect of mandible. Specifically, the main interest for the use of magnetic nanoparticles in biomedical applications is that an inhomogeneous external magnetic field exerts a force on them, and thus they can be manipulated or transported to a specific diseased tissue by a magnetic field gradient. In addition, magnetic particles are of interest because they do not retain any magnetism after removal of the magnetic field. Specifically, inorganic biodegradable nanoparticles (including ceramics, like hydroxyapatite) will be functionalized with bioactive compounds that bond to bone of low mass. Extremely good results in the recovery of alveolar bone osteoporosis were achieved already after 6th week of the application of magnetic nanoparticles. After bonding specifically to osteoporotic bone and not healthy bone, magnetic nanoparticle systems will deliver bioactive compounds to locally increase bone mass. Implantation of magnetic nanoparticles will create bone construction and enable quick formation of new bone and become the material of choice for accelerated bone regeneration.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009
T1  - Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles
SP  - 188
EP  - 188
UR  - https://hdl.handle.net/21.15107/rcub_dais_4934
ER  - 
@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Stojanović, Zoran S. and Kaličanin, Biljana and Savić, Vojin and Petrović, S. M. and Petrović, B. M. and Milićević, Jelena and Uskoković, Dragan",
year = "2009",
abstract = "In this study nanocomposite was used for reconstruction of alveolar bone defect of mandible. Specifically, the main interest for the use of magnetic nanoparticles in biomedical applications is that an inhomogeneous external magnetic field exerts a force on them, and thus they can be manipulated or transported to a specific diseased tissue by a magnetic field gradient. In addition, magnetic particles are of interest because they do not retain any magnetism after removal of the magnetic field. Specifically, inorganic biodegradable nanoparticles (including ceramics, like hydroxyapatite) will be functionalized with bioactive compounds that bond to bone of low mass. Extremely good results in the recovery of alveolar bone osteoporosis were achieved already after 6th week of the application of magnetic nanoparticles. After bonding specifically to osteoporotic bone and not healthy bone, magnetic nanoparticle systems will deliver bioactive compounds to locally increase bone mass. Implantation of magnetic nanoparticles will create bone construction and enable quick formation of new bone and become the material of choice for accelerated bone regeneration.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009",
title = "Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles",
pages = "188-188",
url = "https://hdl.handle.net/21.15107/rcub_dais_4934"
}
Ajduković, Z., Ignjatović, N., Stojanović, Z. S., Kaličanin, B., Savić, V., Petrović, S. M., Petrović, B. M., Milićević, J.,& Uskoković, D. (2009). Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles.
Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009
Belgrade : Institute of Technical Sciences of SASA., 188-188.
Ajduković Z, Ignjatović N, Stojanović ZS, Kaličanin B, Savić V, Petrović SM, Petrović BM, Milićević J, Uskoković D. Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles. Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009. 2009;:188-188.
Ajduković Zorica, Ignjatović Nenad, Stojanović Zoran S., Kaličanin Biljana, Savić Vojin, Petrović S. M., Petrović B. M., Milićević Jelena, Uskoković Dragan, "Treatment of osteoporosis alveolar bone with cobalt substituted hydroxyapatite nanoparticles" Programme and The Book of Abstracts / Eleventh Annual Conference YUCOMAT 2009, Herceg Novi, August 31 – September 4, 2009 (2009):188-188

Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice

Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Savić, Vojin; Ignjatović, Nenad; Uskoković, Dragan

(Beograd : Institut tehničkih nauka, 2009)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Savić, Vojin
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2009
AB  - Osteoporoza kao bolest savremene civilizacije postaje sve aktuelnija u stomatologiji. Jedan od trendova u nalaženju rešenja je u oralnoj implantologiji kroz primenu biomaterijala sa magnetnim česticama. U ovoj studiji ispitivan je uticaj nanočestica Ca/Co-HAp na regeneraciju osteoporotične alveolarne kosti eksperimentalnih životinja analizom biohemijskih markera krvi (Ca, Mg, P). Istraživanje je sprovedeno na 48 Wistar pacovima, starosti 6-8 nedelja kojima je implantiran biometrijal u osteoprotičnoj alveolarnoj kosti. Dobri rezultati regeneracije osteoporotičnog tkiva su postignuti 6 nedelja nakon implantacije nanočestica. Biohemijski parametri koštane sinteze su u statistički značajnom porastu. Implantacija biomaterijala omogućava brzo formiranje nove kosti što ih čini materijalima izbora za ubrzanu regeneraciju kosti.
PB  - Beograd : Institut tehničkih nauka
C3  - Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.
T1  - Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice
SP  - 19
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_dais_4929
ER  - 
@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Savić, Vojin and Ignjatović, Nenad and Uskoković, Dragan",
year = "2009",
abstract = "Osteoporoza kao bolest savremene civilizacije postaje sve aktuelnija u stomatologiji. Jedan od trendova u nalaženju rešenja je u oralnoj implantologiji kroz primenu biomaterijala sa magnetnim česticama. U ovoj studiji ispitivan je uticaj nanočestica Ca/Co-HAp na regeneraciju osteoporotične alveolarne kosti eksperimentalnih životinja analizom biohemijskih markera krvi (Ca, Mg, P). Istraživanje je sprovedeno na 48 Wistar pacovima, starosti 6-8 nedelja kojima je implantiran biometrijal u osteoprotičnoj alveolarnoj kosti. Dobri rezultati regeneracije osteoporotičnog tkiva su postignuti 6 nedelja nakon implantacije nanočestica. Biohemijski parametri koštane sinteze su u statistički značajnom porastu. Implantacija biomaterijala omogućava brzo formiranje nove kosti što ih čini materijalima izbora za ubrzanu regeneraciju kosti.",
publisher = "Beograd : Institut tehničkih nauka",
journal = "Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.",
title = "Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice",
pages = "19-19",
url = "https://hdl.handle.net/21.15107/rcub_dais_4929"
}
Ajduković, Z., Petrović, M. B., Milićević, J., Savić, V., Ignjatović, N.,& Uskoković, D. (2009). Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice.
Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.
Beograd : Institut tehničkih nauka., 19-19.
Ajduković Z, Petrović MB, Milićević J, Savić V, Ignjatović N, Uskoković D. Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice. Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.. 2009;:19-19.
Ajduković Zorica, Petrović Milica B., Milićević Jelena, Savić Vojin, Ignjatović Nenad, Uskoković Dragan, "Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice" Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009. (2009):19-19

Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita

Ajduković, Zorica; Milićević, Jelena; Petrović, Milica B.; Savić, Vojin; Ignjatović, Nenad

(Beograd : Institut tehničkih nauka, 2009)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Savić, Vojin
AU  - Ignjatović, Nenad
PY  - 2009
AB  - Istraživanje je sprovedeno sa ciljem da se dokaže aktivnost alkalne fosfataze, lokalizovane u dekalcifikovanoj kosti, uzete sa leve strane mandibule pacova, u kojoj je arteficijalno napravljen defekt i implantiran nano kalcijum-kobalt hidroksiapatit. Studija je obuhvatila 48 životinja, starosti 6-8 nedelja. Posle šest i dvadeset četiri nedelje od implantacije biomaterijala, uzeti su uzorci za histohemijsku analizu i fiksirani u PLP fiksativu. Zatim su dekalcifikovani, ukalupljeni u parafinski blok i obrađivani za svetlosno-mikroskopska ispitivanja i histohemijsko dokazivanje aktivnosti alkalne fosfataze. Histološka analiza je pokazala visok stepen reparatornih sposobnosti ugrađenog biokompozita u koštani defekat. Histohemijskom analizom je dokazana aktivnost alkalne fosfataze u mineralizovanom tkivu.
PB  - Beograd : Institut tehničkih nauka
C3  - Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009
T1  - Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita
SP  - 20
EP  - 20
UR  - https://hdl.handle.net/21.15107/rcub_dais_4933
ER  - 
@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Savić, Vojin and Ignjatović, Nenad",
year = "2009",
abstract = "Istraživanje je sprovedeno sa ciljem da se dokaže aktivnost alkalne fosfataze, lokalizovane u dekalcifikovanoj kosti, uzete sa leve strane mandibule pacova, u kojoj je arteficijalno napravljen defekt i implantiran nano kalcijum-kobalt hidroksiapatit. Studija je obuhvatila 48 životinja, starosti 6-8 nedelja. Posle šest i dvadeset četiri nedelje od implantacije biomaterijala, uzeti su uzorci za histohemijsku analizu i fiksirani u PLP fiksativu. Zatim su dekalcifikovani, ukalupljeni u parafinski blok i obrađivani za svetlosno-mikroskopska ispitivanja i histohemijsko dokazivanje aktivnosti alkalne fosfataze. Histološka analiza je pokazala visok stepen reparatornih sposobnosti ugrađenog biokompozita u koštani defekat. Histohemijskom analizom je dokazana aktivnost alkalne fosfataze u mineralizovanom tkivu.",
publisher = "Beograd : Institut tehničkih nauka",
journal = "Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009",
title = "Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita",
pages = "20-20",
url = "https://hdl.handle.net/21.15107/rcub_dais_4933"
}
Ajduković, Z., Milićević, J., Petrović, M. B., Savić, V.,& Ignjatović, N. (2009). Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita.
Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009
Beograd : Institut tehničkih nauka., 20-20.
Ajduković Z, Milićević J, Petrović MB, Savić V, Ignjatović N. Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita. Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009. 2009;:20-20.
Ajduković Zorica, Milićević Jelena, Petrović Milica B., Savić Vojin, Ignjatović Nenad, "Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita" Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009 (2009):20-20

Evaluation of glassionomer cement application for permanent binding of prosthetic dentures

Anđelković, Maja; Ajduković, Zorica; Kostić, Milena; Krunić, Nebojša; Kaličanin, Biljana; Ignjatović, Nenad

(Belgrade : Institute of Technical Sciences of SASA, 2007)

TY  - CONF
AU  - Anđelković, Maja
AU  - Ajduković, Zorica
AU  - Kostić, Milena
AU  - Krunić, Nebojša
AU  - Kaličanin, Biljana
AU  - Ignjatović, Nenad
PY  - 2007
AB  - Fixed dentures are created in order to rehabilitate the function of orofacial system, to
correct disordered interdental relation, as well as the relation between jaws and to do esthetic
correction. Binding of fixed dentures to the teeth carriers is done with a layer of binding
biomaterials from the group of dental cements. Cement as the choice of dental biomaterials has
to be the best cement for the most frequent, routine management for these type of works and
most frequently used materials – metal, acrylate, ceramics. Cement must be safe to use with
patients. Ideally, it must have longtime advantages such as to be for various uses, to find the
right balance between results and simplicity of application, which are the most important for
routine management. There are many types of cement. In this study, Zn-phosphate and
glassionomer cement were used. In modern dental technology, production of cement is well
developed and the most concerns are about non-toxicity, biocompatibility, bioinertion,
biofunction. In some cases acidic balance disorder of saliva medium can bring to release of low
doses of heavy metal ions after the reaction of cement and heavy metal ions from dental
compounds. In this study, the best results were achieved with glassionomer cement, because the
lowest percent of released heavy metal ions in saliva medium was noticed after cementing of
fixed dentures by glassionomer cement. Because of its characteristics, glassionomer cement can
be the choice material for permanent cementing of fixed prosthetic dentures.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
T1  - Evaluation of glassionomer cement application for permanent binding of prosthetic dentures
SP  - 179
EP  - 179
UR  - https://hdl.handle.net/21.15107/rcub_dais_6281
ER  - 
@conference{
author = "Anđelković, Maja and Ajduković, Zorica and Kostić, Milena and Krunić, Nebojša and Kaličanin, Biljana and Ignjatović, Nenad",
year = "2007",
abstract = "Fixed dentures are created in order to rehabilitate the function of orofacial system, to
correct disordered interdental relation, as well as the relation between jaws and to do esthetic
correction. Binding of fixed dentures to the teeth carriers is done with a layer of binding
biomaterials from the group of dental cements. Cement as the choice of dental biomaterials has
to be the best cement for the most frequent, routine management for these type of works and
most frequently used materials – metal, acrylate, ceramics. Cement must be safe to use with
patients. Ideally, it must have longtime advantages such as to be for various uses, to find the
right balance between results and simplicity of application, which are the most important for
routine management. There are many types of cement. In this study, Zn-phosphate and
glassionomer cement were used. In modern dental technology, production of cement is well
developed and the most concerns are about non-toxicity, biocompatibility, bioinertion,
biofunction. In some cases acidic balance disorder of saliva medium can bring to release of low
doses of heavy metal ions after the reaction of cement and heavy metal ions from dental
compounds. In this study, the best results were achieved with glassionomer cement, because the
lowest percent of released heavy metal ions in saliva medium was noticed after cementing of
fixed dentures by glassionomer cement. Because of its characteristics, glassionomer cement can
be the choice material for permanent cementing of fixed prosthetic dentures.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007",
title = "Evaluation of glassionomer cement application for permanent binding of prosthetic dentures",
pages = "179-179",
url = "https://hdl.handle.net/21.15107/rcub_dais_6281"
}
Anđelković, M., Ajduković, Z., Kostić, M., Krunić, N., Kaličanin, B.,& Ignjatović, N. (2007). Evaluation of glassionomer cement application for permanent binding of prosthetic dentures.
Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
Belgrade : Institute of Technical Sciences of SASA., 179-179.
Anđelković M, Ajduković Z, Kostić M, Krunić N, Kaličanin B, Ignjatović N. Evaluation of glassionomer cement application for permanent binding of prosthetic dentures. Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007. 2007;:179-179.
Anđelković Maja, Ajduković Zorica, Kostić Milena, Krunić Nebojša, Kaličanin Biljana, Ignjatović Nenad, "Evaluation of glassionomer cement application for permanent binding of prosthetic dentures" Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007 (2007):179-179

Application analysis of micro and nano composites in restoring of bone tissue of the jaw

Ajduković, Zorica; Ignjatović, Nenad; Petrović, Dragan; Savić, Vesna; Kaličanin, Biljana; Anđelković, Maja; Nikolov, S.

(Belgrade : Institute of Technical Sciences of SASA, 2007)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, Dragan
AU  - Savić, Vesna
AU  - Kaličanin, Biljana
AU  - Anđelković, Maja
AU  - Nikolov, S.
PY  - 2007
AB  - Application of synthetic polymer biomaterials is very often used in biomedicine and
dentistry. That’s why the need for creating the new polymer biomaterials is more and more
obvious. Hydroxy-apatite, as a natural constituent of bone, has been already used for many years
in all segments of dentistry. In order to develop better properties, hydroxy-apatite is combined
with polymers. In this research, application of micro and nano composite biomaterials in
reconstruction of osteoporosis damaged alveolar bone of rats is analyzed. Evaluation of
regeneration of restored osteoporosis damaged alveolar bone of rats was done by
histopathological analyses. The optimal results were after 24 weeks after implantation of
calcium-phosphate/poly-D, L-lactide-co-glycolide (CP/DLPLG) composite biomaterials nano
particles in comparison to micro particles. Regeneration and reparation of damaged alveolar
bone with creation of new bone tissue which is very similar to mature bone, are much better on
the place of nano CP/DLPLG implantation. Because of its very good osteoconductive effect,
applied nano CP/DLPLG composite can totally renew lost bone tissue, so it can be the material
of choice for the alveolar bone defect rehabilitation.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
T1  - Application analysis of micro and nano composites in restoring of bone tissue of the jaw
SP  - 178
EP  - 178
UR  - https://hdl.handle.net/21.15107/rcub_dais_6295
ER  - 
@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, Dragan and Savić, Vesna and Kaličanin, Biljana and Anđelković, Maja and Nikolov, S.",
year = "2007",
abstract = "Application of synthetic polymer biomaterials is very often used in biomedicine and
dentistry. That’s why the need for creating the new polymer biomaterials is more and more
obvious. Hydroxy-apatite, as a natural constituent of bone, has been already used for many years
in all segments of dentistry. In order to develop better properties, hydroxy-apatite is combined
with polymers. In this research, application of micro and nano composite biomaterials in
reconstruction of osteoporosis damaged alveolar bone of rats is analyzed. Evaluation of
regeneration of restored osteoporosis damaged alveolar bone of rats was done by
histopathological analyses. The optimal results were after 24 weeks after implantation of
calcium-phosphate/poly-D, L-lactide-co-glycolide (CP/DLPLG) composite biomaterials nano
particles in comparison to micro particles. Regeneration and reparation of damaged alveolar
bone with creation of new bone tissue which is very similar to mature bone, are much better on
the place of nano CP/DLPLG implantation. Because of its very good osteoconductive effect,
applied nano CP/DLPLG composite can totally renew lost bone tissue, so it can be the material
of choice for the alveolar bone defect rehabilitation.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007",
title = "Application analysis of micro and nano composites in restoring of bone tissue of the jaw",
pages = "178-178",
url = "https://hdl.handle.net/21.15107/rcub_dais_6295"
}
Ajduković, Z., Ignjatović, N., Petrović, D., Savić, V., Kaličanin, B., Anđelković, M.,& Nikolov, S. (2007). Application analysis of micro and nano composites in restoring of bone tissue of the jaw.
Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
Belgrade : Institute of Technical Sciences of SASA., 178-178.
Ajduković Z, Ignjatović N, Petrović D, Savić V, Kaličanin B, Anđelković M, Nikolov S. Application analysis of micro and nano composites in restoring of bone tissue of the jaw. Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007. 2007;:178-178.
Ajduković Zorica, Ignjatović Nenad, Petrović Dragan, Savić Vesna, Kaličanin Biljana, Anđelković Maja, Nikolov S., "Application analysis of micro and nano composites in restoring of bone tissue of the jaw" Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007 (2007):178-178