Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou

Link to this page

info:eu-repo/grantAgreement/MESTD/MPN2006-2010/142006/RS//

Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (en)
Синтеза функционалних материјала са контролисаном структуром на молекуларном и нано нивоу (sr)
Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (sr_RS)
Authors

Publications

Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery

Vukomanović, Marija; Škapin, Srečo Davor; Jančar, Boštjan; Maksin, Tatjana; Ignjatović, Nenad; Uskoković, Vuk; Uskoković, Dragan

(2011)

TY  - JOUR
AU  - Vukomanović, Marija
AU  - Škapin, Srečo Davor
AU  - Jančar, Boštjan
AU  - Maksin, Tatjana
AU  - Ignjatović, Nenad
AU  - Uskoković, Vuk
AU  - Uskoković, Dragan
PY  - 2011
UR  - http://dais.sanu.ac.rs/123456789/2749
AB  - Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces B: Biointerfaces
T1  - Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery
SP  - 404
EP  - 413
VL  - 82
IS  - 2
DO  - 10.1016/j.colsurfb.2010.09.011
UR  - https://hdl.handle.net/21.15107/rcub_dais_2749
ER  - 
@article{
author = "Vukomanović, Marija and Škapin, Srečo Davor and Jančar, Boštjan and Maksin, Tatjana and Ignjatović, Nenad and Uskoković, Vuk and Uskoković, Dragan",
year = "2011",
abstract = "Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces B: Biointerfaces",
title = "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery",
pages = "404-413",
volume = "82",
number = "2",
doi = "10.1016/j.colsurfb.2010.09.011",
url = "https://hdl.handle.net/21.15107/rcub_dais_2749"
}
Vukomanović, M., Škapin, S. D., Jančar, B., Maksin, T., Ignjatović, N., Uskoković, V.,& Uskoković, D.. (2011). Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces B: Biointerfaces, 82(2), 404-413.
https://doi.org/10.1016/j.colsurfb.2010.09.011
https://hdl.handle.net/21.15107/rcub_dais_2749
Vukomanović M, Škapin SD, Jančar B, Maksin T, Ignjatović N, Uskoković V, Uskoković D. Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces B: Biointerfaces. 2011;82(2):404-413.
doi:10.1016/j.colsurfb.2010.09.011
https://hdl.handle.net/21.15107/rcub_dais_2749 .
Vukomanović, Marija, Škapin, Srečo Davor, Jančar, Boštjan, Maksin, Tatjana, Ignjatović, Nenad, Uskoković, Vuk, Uskoković, Dragan, "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery" in Colloids and Surfaces B: Biointerfaces, 82, no. 2 (2011):404-413,
https://doi.org/10.1016/j.colsurfb.2010.09.011 .,
https://hdl.handle.net/21.15107/rcub_dais_2749 .
6
26
25
27

Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles

Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Đorđević, Nadica; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin P.

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, Nadica
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin P.
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3446
AB  - This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the mineralized tissues. It can be concluded that Ca/Co-HAp stimulates the regeneration of osteoporotic alveolar bone in tested animals as confirmed by the increased levels of biochemical blood markers and through histochemical analysis. Therefore, it can be concluded that Ca/Co-HAp nanocomposite should be choise material in the osteoconstructive processes in the future.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 19
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_dais_3446
ER  - 
@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, Nadica and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin P.",
year = "2010",
abstract = "This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the mineralized tissues. It can be concluded that Ca/Co-HAp stimulates the regeneration of osteoporotic alveolar bone in tested animals as confirmed by the increased levels of biochemical blood markers and through histochemical analysis. Therefore, it can be concluded that Ca/Co-HAp nanocomposite should be choise material in the osteoconstructive processes in the future.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "19-19",
url = "https://hdl.handle.net/21.15107/rcub_dais_3446"
}
Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V. P.. (2010). Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 19-19.
https://hdl.handle.net/21.15107/rcub_dais_3446
Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić VP. Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:19-19.
https://hdl.handle.net/21.15107/rcub_dais_3446 .
Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, Nadica, Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin P., "Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):19-19,
https://hdl.handle.net/21.15107/rcub_dais_3446 .

In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite

Ajduković, Zorica; Milićević, Jelena; Petrović, Milica B.; Đorđević, Nadica; Mladenović Antić, Snežana; Kocić, Branislava; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin P.

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Đorđević, Nadica
AU  - Mladenović Antić, Snežana
AU  - Kocić, Branislava
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin P.
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3444
AB  - Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted calcium hydroxyapatite nanopowders and biphased calciumphosphate/ poli-lactide-co-glicolide. The antimicrobial effects of these substances (powders) against two pathogen bacterial strains- Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were tested by disc diffusion method and quantitative antimicrobial test in liquid medium. It was noted that the inhibition zone of the bacterial cells S. aureus around the sample of the Ca/Co- HAp, was a lot bigger compared to the inhibition zone of bacterial cells E. coli around the sample of the mentioned biomaterial, which means that this material has bigger antimicrobic activity on S. aureus, in relation to E. coli. Quantitative antimicrobial test in liquid medium demonstrate that cobalt-substituted calcium hydroxyapatite samples show viable cells reduction of both tested microorganisms. It may be concluded that nanoparticles of cobalt-substituted calcium hydoxyapatite nano-powders has a satisfactory antimicrobic activity according to the tested bacteria strain.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite
SP  - 18
EP  - 18
UR  - https://hdl.handle.net/21.15107/rcub_dais_3444
ER  - 
@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Đorđević, Nadica and Mladenović Antić, Snežana and Kocić, Branislava and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin P.",
year = "2010",
abstract = "Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted calcium hydroxyapatite nanopowders and biphased calciumphosphate/ poli-lactide-co-glicolide. The antimicrobial effects of these substances (powders) against two pathogen bacterial strains- Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were tested by disc diffusion method and quantitative antimicrobial test in liquid medium. It was noted that the inhibition zone of the bacterial cells S. aureus around the sample of the Ca/Co- HAp, was a lot bigger compared to the inhibition zone of bacterial cells E. coli around the sample of the mentioned biomaterial, which means that this material has bigger antimicrobic activity on S. aureus, in relation to E. coli. Quantitative antimicrobial test in liquid medium demonstrate that cobalt-substituted calcium hydroxyapatite samples show viable cells reduction of both tested microorganisms. It may be concluded that nanoparticles of cobalt-substituted calcium hydoxyapatite nano-powders has a satisfactory antimicrobic activity according to the tested bacteria strain.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite",
pages = "18-18",
url = "https://hdl.handle.net/21.15107/rcub_dais_3444"
}
Ajduković, Z., Milićević, J., Petrović, M. B., Đorđević, N., Mladenović Antić, S., Kocić, B., Ignjatović, N., Uskoković, D.,& Savić, V. P.. (2010). In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 18-18.
https://hdl.handle.net/21.15107/rcub_dais_3444
Ajduković Z, Milićević J, Petrović MB, Đorđević N, Mladenović Antić S, Kocić B, Ignjatović N, Uskoković D, Savić VP. In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:18-18.
https://hdl.handle.net/21.15107/rcub_dais_3444 .
Ajduković, Zorica, Milićević, Jelena, Petrović, Milica B., Đorđević, Nadica, Mladenović Antić, Snežana, Kocić, Branislava, Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin P., "In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):18-18,
https://hdl.handle.net/21.15107/rcub_dais_3444 .

Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro

Ajduković, Zorica; Milićević, Jelena; Petrović, Milica B.; Đorđević, N.; Ignjatović, Nenad; Savić, Vojin P.; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Savić, Vojin P.
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3553
AB  - Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- hydroxyapatite and biphasic calcium phosphate/ poly (lactide-co-glycolide) composite biomaterial. Antimicrobial activity of the samples was tested using dilution method and disk diffusion. The results of antimicrobial tests were obtained by determining the reduction percentage the number of bacteria in physiological solution where bacteria cells were exposed to the samples. It can be concluded that synthesized HAp biomaterials have satisfactory antimicrobial activity against tested bacteria strains.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro
SP  - 168
EP  - 168
UR  - https://hdl.handle.net/21.15107/rcub_dais_3553
ER  - 
@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Đorđević, N. and Ignjatović, Nenad and Savić, Vojin P. and Uskoković, Dragan",
year = "2010",
abstract = "Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- hydroxyapatite and biphasic calcium phosphate/ poly (lactide-co-glycolide) composite biomaterial. Antimicrobial activity of the samples was tested using dilution method and disk diffusion. The results of antimicrobial tests were obtained by determining the reduction percentage the number of bacteria in physiological solution where bacteria cells were exposed to the samples. It can be concluded that synthesized HAp biomaterials have satisfactory antimicrobial activity against tested bacteria strains.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro",
pages = "168-168",
url = "https://hdl.handle.net/21.15107/rcub_dais_3553"
}
Ajduković, Z., Milićević, J., Petrović, M. B., Đorđević, N., Ignjatović, N., Savić, V. P.,& Uskoković, D.. (2010). Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 168-168.
https://hdl.handle.net/21.15107/rcub_dais_3553
Ajduković Z, Milićević J, Petrović MB, Đorđević N, Ignjatović N, Savić VP, Uskoković D. Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:168-168.
https://hdl.handle.net/21.15107/rcub_dais_3553 .
Ajduković, Zorica, Milićević, Jelena, Petrović, Milica B., Đorđević, N., Ignjatović, Nenad, Savić, Vojin P., Uskoković, Dragan, "Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):168-168,
https://hdl.handle.net/21.15107/rcub_dais_3553 .

Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles

Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Đorđević, N.; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3552
AB  - One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 167
EP  - 167
UR  - https://hdl.handle.net/21.15107/rcub_dais_3552
ER  - 
@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, N. and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin",
year = "2010",
abstract = "One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "167-167",
url = "https://hdl.handle.net/21.15107/rcub_dais_3552"
}
Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V.. (2010). Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 167-167.
https://hdl.handle.net/21.15107/rcub_dais_3552
Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić V. Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:167-167.
https://hdl.handle.net/21.15107/rcub_dais_3552 .
Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, N., Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin, "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):167-167,
https://hdl.handle.net/21.15107/rcub_dais_3552 .

Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol

Stojanović, D.; Orlović, A.; Glišić, S. B.; Marković, Smilja; Radmilović, Velimir R.; Uskoković, Petar S.; Aleksić, Radoslav

(Elsevier, 2010)

TY  - JOUR
AU  - Stojanović, D.
AU  - Orlović, A.
AU  - Glišić, S. B.
AU  - Marković, Smilja
AU  - Radmilović, Velimir R.
AU  - Uskoković, Petar S.
AU  - Aleksić, Radoslav
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3427
AB  - The objective of this study is to investigate and compare methods of nanosilica coating with γ-methacryloxypropyltrimethoxy (MEMO) silane using supercritical carbon dioxide and carbon dioxide-ethanol mixture. Characterization of grafted silane coupling agent on the nanosilica surface was performed by the infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The d50 value and particle size distribution were determined by laser particle size analyzer (PSA). The operating parameters of silanization process at 40 °C, such as the silica/silane weight ratio, the presence of ethanol, and the pressure, were found to be important for the successful coating of silica particles with minimum agglomeration. The results indicate that presence of ethanol in high-pressure carbon dioxide plays an important role in achieving successful deagglomeration of coated nanoparticles. Dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM) revealed that dispersion of the silica particles in the PMMA matrix and interfacial adhesion between silica particles and polymer matrix were enhanced, when silica nanoparticles treated with silane under high pressure of carbon dioxide and ethanol were used for the nanocomposite preparation. © 2010 Elsevier B.V. All rights reserved.
PB  - Elsevier
T2  - Journal of Supercritical Fluids
T1  - Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol
SP  - 276
EP  - 284
VL  - 52
IS  - 3
DO  - 10.1016/j.supflu.2010.02.004
UR  - https://hdl.handle.net/21.15107/rcub_dais_3427
ER  - 
@article{
author = "Stojanović, D. and Orlović, A. and Glišić, S. B. and Marković, Smilja and Radmilović, Velimir R. and Uskoković, Petar S. and Aleksić, Radoslav",
year = "2010",
abstract = "The objective of this study is to investigate and compare methods of nanosilica coating with γ-methacryloxypropyltrimethoxy (MEMO) silane using supercritical carbon dioxide and carbon dioxide-ethanol mixture. Characterization of grafted silane coupling agent on the nanosilica surface was performed by the infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The d50 value and particle size distribution were determined by laser particle size analyzer (PSA). The operating parameters of silanization process at 40 °C, such as the silica/silane weight ratio, the presence of ethanol, and the pressure, were found to be important for the successful coating of silica particles with minimum agglomeration. The results indicate that presence of ethanol in high-pressure carbon dioxide plays an important role in achieving successful deagglomeration of coated nanoparticles. Dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM) revealed that dispersion of the silica particles in the PMMA matrix and interfacial adhesion between silica particles and polymer matrix were enhanced, when silica nanoparticles treated with silane under high pressure of carbon dioxide and ethanol were used for the nanocomposite preparation. © 2010 Elsevier B.V. All rights reserved.",
publisher = "Elsevier",
journal = "Journal of Supercritical Fluids",
title = "Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol",
pages = "276-284",
volume = "52",
number = "3",
doi = "10.1016/j.supflu.2010.02.004",
url = "https://hdl.handle.net/21.15107/rcub_dais_3427"
}
Stojanović, D., Orlović, A., Glišić, S. B., Marković, S., Radmilović, V. R., Uskoković, P. S.,& Aleksić, R.. (2010). Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol. in Journal of Supercritical Fluids
Elsevier., 52(3), 276-284.
https://doi.org/10.1016/j.supflu.2010.02.004
https://hdl.handle.net/21.15107/rcub_dais_3427
Stojanović D, Orlović A, Glišić SB, Marković S, Radmilović VR, Uskoković PS, Aleksić R. Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol. in Journal of Supercritical Fluids. 2010;52(3):276-284.
doi:10.1016/j.supflu.2010.02.004
https://hdl.handle.net/21.15107/rcub_dais_3427 .
Stojanović, D., Orlović, A., Glišić, S. B., Marković, Smilja, Radmilović, Velimir R., Uskoković, Petar S., Aleksić, Radoslav, "Preparation of MEMO silane-coated SiO2 nanoparticles under high pressure of carbon dioxide and ethanol" in Journal of Supercritical Fluids, 52, no. 3 (2010):276-284,
https://doi.org/10.1016/j.supflu.2010.02.004 .,
https://hdl.handle.net/21.15107/rcub_dais_3427 .
25
21
29

Rietveld powder data file for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327

Veselinović, Ljiljana; Karanović, Ljiljana; Bračko, Ines; Marković, Smilja; Ignjatović, Nenad; Uskoković, Dragan

(2010)

TY  - DATA
AU  - Veselinović, Ljiljana
AU  - Karanović, Ljiljana
AU  - Bračko, Ines
AU  - Marković, Smilja
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3442
AB  - Rietveld powder data file contains datablocks HAp, Co5HAp, Co10HAp, Co15HAp, Co20HAp
T2  - Journal of Applied Crystallography
T1  - Rietveld powder data file for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327
UR  - https://hdl.handle.net/21.15107/rcub_dais_3442
ER  - 
@misc{
author = "Veselinović, Ljiljana and Karanović, Ljiljana and Bračko, Ines and Marković, Smilja and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
abstract = "Rietveld powder data file contains datablocks HAp, Co5HAp, Co10HAp, Co15HAp, Co20HAp",
journal = "Journal of Applied Crystallography",
title = "Rietveld powder data file for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327",
url = "https://hdl.handle.net/21.15107/rcub_dais_3442"
}
Veselinović, L., Karanović, L., Bračko, I., Marković, S., Ignjatović, N.,& Uskoković, D.. (2010). Rietveld powder data file for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327. in Journal of Applied Crystallography.
https://hdl.handle.net/21.15107/rcub_dais_3442
Veselinović L, Karanović L, Bračko I, Marković S, Ignjatović N, Uskoković D. Rietveld powder data file for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327. in Journal of Applied Crystallography. 2010;.
https://hdl.handle.net/21.15107/rcub_dais_3442 .
Veselinović, Ljiljana, Karanović, Ljiljana, Bračko, Ines, Marković, Smilja, Ignjatović, Nenad, Uskoković, Dragan, "Rietveld powder data file for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327" in Journal of Applied Crystallography (2010),
https://hdl.handle.net/21.15107/rcub_dais_3442 .

Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material

Jović, Maja; Jugović, Dragana; Mitrić, Miodrag; Cvjetićanin, Nikola; Škapin, Srečo Davor; Uskoković, Dragan

(2010)

TY  - CONF
AU  - Jović, Maja
AU  - Jugović, Dragana
AU  - Mitrić, Miodrag
AU  - Cvjetićanin, Nikola
AU  - Škapin, Srečo Davor
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/242
AB  - Poster presented at the 12th Annual Conference of the Materials Research Society of Serbia - YUCOMAT 2010, Herceg Novi, Montenegro, September 6–10, 2010.
AB  - LiFePO4 is a material of great interest as cathode material for lithium ion batteries thanks to its good characteristics. One of the advanced techniques for LiFePO4 powder preparation is hydrothermal synthesis. In this work, LiFePO4 powders were prepared by a new approach, a microemulsion-mediated hydrothermal method in which microemulsion medium was further treated by hydrothermal reaction. The main advantage of the proposed route is low reaction temperature and short processing time that prevents agglomeration in the formed particles. LiFePO4 powders were prepared by microemulsion-mediated hydrothermal method in cyclohexane/Triton X-100/n-hexanole/water at 180 °C. The product of hydrothermal synthesis was heat treated in reductive atmosphere to avoid oxidation of Fe2+ to Fe3+. Powders were characterized by X-ray diffraction, scanning electron microscopy and galvanostatic charge-discharge cycling.
T1  - Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material
UR  - https://hdl.handle.net/21.15107/rcub_dais_242
ER  - 
@conference{
author = "Jović, Maja and Jugović, Dragana and Mitrić, Miodrag and Cvjetićanin, Nikola and Škapin, Srečo Davor and Uskoković, Dragan",
year = "2010",
abstract = "Poster presented at the 12th Annual Conference of the Materials Research Society of Serbia - YUCOMAT 2010, Herceg Novi, Montenegro, September 6–10, 2010., LiFePO4 is a material of great interest as cathode material for lithium ion batteries thanks to its good characteristics. One of the advanced techniques for LiFePO4 powder preparation is hydrothermal synthesis. In this work, LiFePO4 powders were prepared by a new approach, a microemulsion-mediated hydrothermal method in which microemulsion medium was further treated by hydrothermal reaction. The main advantage of the proposed route is low reaction temperature and short processing time that prevents agglomeration in the formed particles. LiFePO4 powders were prepared by microemulsion-mediated hydrothermal method in cyclohexane/Triton X-100/n-hexanole/water at 180 °C. The product of hydrothermal synthesis was heat treated in reductive atmosphere to avoid oxidation of Fe2+ to Fe3+. Powders were characterized by X-ray diffraction, scanning electron microscopy and galvanostatic charge-discharge cycling.",
title = "Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material",
url = "https://hdl.handle.net/21.15107/rcub_dais_242"
}
Jović, M., Jugović, D., Mitrić, M., Cvjetićanin, N., Škapin, S. D.,& Uskoković, D.. (2010). Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material. .
https://hdl.handle.net/21.15107/rcub_dais_242
Jović M, Jugović D, Mitrić M, Cvjetićanin N, Škapin SD, Uskoković D. Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material. 2010;.
https://hdl.handle.net/21.15107/rcub_dais_242 .
Jović, Maja, Jugović, Dragana, Mitrić, Miodrag, Cvjetićanin, Nikola, Škapin, Srečo Davor, Uskoković, Dragan, "Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material" (2010),
https://hdl.handle.net/21.15107/rcub_dais_242 .

Preparation of LiFePO4/C composites by co-precipitation in the presence of stearic acid

Jugović, Dragana; Jović, Maja; Mitrić, Miodrag; Cvjetićanin, Nikola; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Jugović, Dragana
AU  - Jović, Maja
AU  - Mitrić, Miodrag
AU  - Cvjetićanin, Nikola
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3556
AB  - The olivine type compositions LiMPO4 (M = Fe, Mn, Co) are among the most attractive materials for the positive electrode of lithium-ion battery. The benefits of using LiFePO4 are excellent cycle life, high structural stability, low cost and environmental friendliness. Its main limitation is low total electrical conductivity, which can be overcome by carbon coating and/or the achievement of a small and homogeneous particle size distribution. Here is presented a simple and inexpensive route for obtaining LiFePO4/C composites by aqueous co-precipitation of an Fe(II) precursor material in the presence of stearic acid and subsequent heat treatment at different temperatures. Stearic acid serves as both chelating agent and carbonaceous material. During pyrolytic degradation stearic acid decomposes to carbon while creating reductive atmosphere. The crystal structures of the powders were revealed by X-ray powder diffraction. It was shown that phase purity of the synthesized powders is very dependent on calcination temperature, as well as their electrochemical properties.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Preparation of LiFePO4/C composites by co-precipitation in the presence of stearic acid
SP  - 10
EP  - 10
UR  - https://hdl.handle.net/21.15107/rcub_dais_3556
ER  - 
@conference{
author = "Jugović, Dragana and Jović, Maja and Mitrić, Miodrag and Cvjetićanin, Nikola and Uskoković, Dragan",
year = "2010",
abstract = "The olivine type compositions LiMPO4 (M = Fe, Mn, Co) are among the most attractive materials for the positive electrode of lithium-ion battery. The benefits of using LiFePO4 are excellent cycle life, high structural stability, low cost and environmental friendliness. Its main limitation is low total electrical conductivity, which can be overcome by carbon coating and/or the achievement of a small and homogeneous particle size distribution. Here is presented a simple and inexpensive route for obtaining LiFePO4/C composites by aqueous co-precipitation of an Fe(II) precursor material in the presence of stearic acid and subsequent heat treatment at different temperatures. Stearic acid serves as both chelating agent and carbonaceous material. During pyrolytic degradation stearic acid decomposes to carbon while creating reductive atmosphere. The crystal structures of the powders were revealed by X-ray powder diffraction. It was shown that phase purity of the synthesized powders is very dependent on calcination temperature, as well as their electrochemical properties.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Preparation of LiFePO4/C composites by co-precipitation in the presence of stearic acid",
pages = "10-10",
url = "https://hdl.handle.net/21.15107/rcub_dais_3556"
}
Jugović, D., Jović, M., Mitrić, M., Cvjetićanin, N.,& Uskoković, D.. (2010). Preparation of LiFePO4/C composites by co-precipitation in the presence of stearic acid. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 10-10.
https://hdl.handle.net/21.15107/rcub_dais_3556
Jugović D, Jović M, Mitrić M, Cvjetićanin N, Uskoković D. Preparation of LiFePO4/C composites by co-precipitation in the presence of stearic acid. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:10-10.
https://hdl.handle.net/21.15107/rcub_dais_3556 .
Jugović, Dragana, Jović, Maja, Mitrić, Miodrag, Cvjetićanin, Nikola, Uskoković, Dragan, "Preparation of LiFePO4/C composites by co-precipitation in the presence of stearic acid" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):10-10,
https://hdl.handle.net/21.15107/rcub_dais_3556 .

Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material

Jović, Maja; Jugović, Dragana; Mitrić, Miodrag; Cvjetićanin, Nikola; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Jović, Maja
AU  - Jugović, Dragana
AU  - Mitrić, Miodrag
AU  - Cvjetićanin, Nikola
AU  - Uskoković, Dragan
PY  - 2010
UR  - 9788680321189
UR  - http://dais.sanu.ac.rs/123456789/3555
AB  - LiFePO4 is a material of great interest as cathode material for lithium ion batteries thanks to its good characteristics. One of the advanced techniques for LiFePO4 powder preparation is hydrothermal synthesis. In this work, LiFePO4 powders were prepared by a new approach, a microemulsion-mediated hydrothermal method in which microemulsion medium was further treated by hydrothermal reaction. The main advantage of the proposed route is low reaction temperature and short processing time that prevents agglomeration in the formed particles. LiFePO4 powders were prepared by microemulsion-mediated hydrothermal method in cyclohexane/Triton X-100/n-hexanole/water at 180 °C. The product of hydrothermal synthesis was heat treated in reductive atmosphere to avoid oxidation of Fe2+ to Fe3+. Powders were characterized by X-ray diffraction, scanning electron microscopy and galvanostatic charge-discharge cycling.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material
SP  - 71
EP  - 71
UR  - https://hdl.handle.net/21.15107/rcub_dais_3555
ER  - 
@conference{
author = "Jović, Maja and Jugović, Dragana and Mitrić, Miodrag and Cvjetićanin, Nikola and Uskoković, Dragan",
year = "2010",
abstract = "LiFePO4 is a material of great interest as cathode material for lithium ion batteries thanks to its good characteristics. One of the advanced techniques for LiFePO4 powder preparation is hydrothermal synthesis. In this work, LiFePO4 powders were prepared by a new approach, a microemulsion-mediated hydrothermal method in which microemulsion medium was further treated by hydrothermal reaction. The main advantage of the proposed route is low reaction temperature and short processing time that prevents agglomeration in the formed particles. LiFePO4 powders were prepared by microemulsion-mediated hydrothermal method in cyclohexane/Triton X-100/n-hexanole/water at 180 °C. The product of hydrothermal synthesis was heat treated in reductive atmosphere to avoid oxidation of Fe2+ to Fe3+. Powders were characterized by X-ray diffraction, scanning electron microscopy and galvanostatic charge-discharge cycling.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material",
pages = "71-71",
url = "https://hdl.handle.net/21.15107/rcub_dais_3555"
}
Jović, M., Jugović, D., Mitrić, M., Cvjetićanin, N.,& Uskoković, D.. (2010). Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 71-71.
https://hdl.handle.net/21.15107/rcub_dais_3555
Jović M, Jugović D, Mitrić M, Cvjetićanin N, Uskoković D. Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:71-71.
https://hdl.handle.net/21.15107/rcub_dais_3555 .
Jović, Maja, Jugović, Dragana, Mitrić, Miodrag, Cvjetićanin, Nikola, Uskoković, Dragan, "Microemulsion-mediated hydrothermal synthesis of LiFePO4 cathode material" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):71-71,
https://hdl.handle.net/21.15107/rcub_dais_3555 .

Crystal growth of solvothermally obtained LiFePO4 in dependence of synthesis conditions

Kuzmanović, Maja; Jugović, Dragana; Mitrić, Miodrag; Cvjetićanin, Nikola; Škapin, Srečo Davor; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Kuzmanović, Maja
AU  - Jugović, Dragana
AU  - Mitrić, Miodrag
AU  - Cvjetićanin, Nikola
AU  - Škapin, Srečo Davor
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3448
AB  - Olivine type LiFePO4 is a promising cathode material for the use in lithium ion batteries, especially in the batteries for hybrid electric vehicles or pure electric vehicles. In this work, LiFePO4 was synthesized by solvothermal method at 180oC, for 15 hours. The n-hexanol was used as a solvent with cyclohexane and Triton X-100 as co-solvent and surfactant, respectively. The powders were annealed at elevated temperatures with addition of oxalic acid as carbon source. The conditions of solvothermal synthesis and the presence of the oxalic acid played important role in the crystal growth mechanism. Powders were characterized by X-ray diffraction, scanning electron microscopy and galvanostatic charge-discharge cycling.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Crystal growth of solvothermally obtained LiFePO4 in dependence of synthesis conditions
SP  - 8
EP  - 8
UR  - https://hdl.handle.net/21.15107/rcub_dais_3448
ER  - 
@conference{
author = "Kuzmanović, Maja and Jugović, Dragana and Mitrić, Miodrag and Cvjetićanin, Nikola and Škapin, Srečo Davor and Uskoković, Dragan",
year = "2010",
abstract = "Olivine type LiFePO4 is a promising cathode material for the use in lithium ion batteries, especially in the batteries for hybrid electric vehicles or pure electric vehicles. In this work, LiFePO4 was synthesized by solvothermal method at 180oC, for 15 hours. The n-hexanol was used as a solvent with cyclohexane and Triton X-100 as co-solvent and surfactant, respectively. The powders were annealed at elevated temperatures with addition of oxalic acid as carbon source. The conditions of solvothermal synthesis and the presence of the oxalic acid played important role in the crystal growth mechanism. Powders were characterized by X-ray diffraction, scanning electron microscopy and galvanostatic charge-discharge cycling.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Crystal growth of solvothermally obtained LiFePO4 in dependence of synthesis conditions",
pages = "8-8",
url = "https://hdl.handle.net/21.15107/rcub_dais_3448"
}
Kuzmanović, M., Jugović, D., Mitrić, M., Cvjetićanin, N., Škapin, S. D.,& Uskoković, D.. (2010). Crystal growth of solvothermally obtained LiFePO4 in dependence of synthesis conditions. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 8-8.
https://hdl.handle.net/21.15107/rcub_dais_3448
Kuzmanović M, Jugović D, Mitrić M, Cvjetićanin N, Škapin SD, Uskoković D. Crystal growth of solvothermally obtained LiFePO4 in dependence of synthesis conditions. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:8-8.
https://hdl.handle.net/21.15107/rcub_dais_3448 .
Kuzmanović, Maja, Jugović, Dragana, Mitrić, Miodrag, Cvjetićanin, Nikola, Škapin, Srečo Davor, Uskoković, Dragan, "Crystal growth of solvothermally obtained LiFePO4 in dependence of synthesis conditions" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):8-8,
https://hdl.handle.net/21.15107/rcub_dais_3448 .

Surface characterisation of PLLA polymer in HAp/PLLA biocomposite material by means of nanoindentation and artificial neural networks

Aleksendrić, D.; Balać, Igor; Tang, C. Y.; Tsui, C. P.; Uskoković, Petar S.; Uskoković, Dragan

(Maney Publishing, 2010)

TY  - JOUR
AU  - Aleksendrić, D.
AU  - Balać, Igor
AU  - Tang, C. Y.
AU  - Tsui, C. P.
AU  - Uskoković, Petar S.
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3432
AB  - In this paper, the mechanical properties of polymer matrix phase (modulus of elasticity, yield stress and work hardening rate) have been determined using combined methods such as nanoindentation, finite element modelling and artificial neural networks. The approach of neural modelling has been employed for the functional approximation of the nanoindentation load-displacement curves. The data obtained from finite element analyses have been used for the artificial neural networks training and validating. The neural model of polymer matrix phase of poly-l-lactide (PLLA) polymer in hydroxyapatite (HAp)/PLLA mechanical behaviour has been developed and tested versus unknown data related to the load-displacement curves that were not used during the neural network training. Based on this neural model, the nanoindentation matrix phase properties of PLLA polymer in HAp/PLLA composite have been predicted. © 2010 Institute of Materials, Minerals and Mining.
PB  - Maney Publishing
T2  - Advances in Applied Ceramics
T1  - Surface characterisation of PLLA polymer in HAp/PLLA biocomposite material by means of nanoindentation and artificial neural networks
SP  - 65
EP  - 70
VL  - 109
IS  - 2
DO  - 10.1179/174367509X12502621261613
UR  - https://hdl.handle.net/21.15107/rcub_dais_3432
ER  - 
@article{
author = "Aleksendrić, D. and Balać, Igor and Tang, C. Y. and Tsui, C. P. and Uskoković, Petar S. and Uskoković, Dragan",
year = "2010",
abstract = "In this paper, the mechanical properties of polymer matrix phase (modulus of elasticity, yield stress and work hardening rate) have been determined using combined methods such as nanoindentation, finite element modelling and artificial neural networks. The approach of neural modelling has been employed for the functional approximation of the nanoindentation load-displacement curves. The data obtained from finite element analyses have been used for the artificial neural networks training and validating. The neural model of polymer matrix phase of poly-l-lactide (PLLA) polymer in hydroxyapatite (HAp)/PLLA mechanical behaviour has been developed and tested versus unknown data related to the load-displacement curves that were not used during the neural network training. Based on this neural model, the nanoindentation matrix phase properties of PLLA polymer in HAp/PLLA composite have been predicted. © 2010 Institute of Materials, Minerals and Mining.",
publisher = "Maney Publishing",
journal = "Advances in Applied Ceramics",
title = "Surface characterisation of PLLA polymer in HAp/PLLA biocomposite material by means of nanoindentation and artificial neural networks",
pages = "65-70",
volume = "109",
number = "2",
doi = "10.1179/174367509X12502621261613",
url = "https://hdl.handle.net/21.15107/rcub_dais_3432"
}
Aleksendrić, D., Balać, I., Tang, C. Y., Tsui, C. P., Uskoković, P. S.,& Uskoković, D.. (2010). Surface characterisation of PLLA polymer in HAp/PLLA biocomposite material by means of nanoindentation and artificial neural networks. in Advances in Applied Ceramics
Maney Publishing., 109(2), 65-70.
https://doi.org/10.1179/174367509X12502621261613
https://hdl.handle.net/21.15107/rcub_dais_3432
Aleksendrić D, Balać I, Tang CY, Tsui CP, Uskoković PS, Uskoković D. Surface characterisation of PLLA polymer in HAp/PLLA biocomposite material by means of nanoindentation and artificial neural networks. in Advances in Applied Ceramics. 2010;109(2):65-70.
doi:10.1179/174367509X12502621261613
https://hdl.handle.net/21.15107/rcub_dais_3432 .
Aleksendrić, D., Balać, Igor, Tang, C. Y., Tsui, C. P., Uskoković, Petar S., Uskoković, Dragan, "Surface characterisation of PLLA polymer in HAp/PLLA biocomposite material by means of nanoindentation and artificial neural networks" in Advances in Applied Ceramics, 109, no. 2 (2010):65-70,
https://doi.org/10.1179/174367509X12502621261613 .,
https://hdl.handle.net/21.15107/rcub_dais_3432 .
5
5
6

Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing

Veselinović, Ljiljana; Karanović, Ljiljana; Stojanović, Zoran S.; Bračko, Ines; Marković, Smilja; Ignjatović, Nenad; Uskoković, Dragan

(Chester: International Union of Crystallography, 2010)

TY  - JOUR
AU  - Veselinović, Ljiljana
AU  - Karanović, Ljiljana
AU  - Stojanović, Zoran S.
AU  - Bračko, Ines
AU  - Marković, Smilja
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3428
AB  - A series of cobalt-exchanged hydroxyapatite (CoHAp) powders with different Ca/Co ratios and nominal unit-cell contents Ca10-x Cox (PO4)6(OH)2, x = 0, 0.5, 1.0, 1.5 and 2.0, were synthesized by hydrothermal treatment of a precipitate at 473 K for 8 h. Based on ICP (inductively coupled plasma) emission spectroscopy analysis, it was established that the maximum amount of cobalt incorporation saturated at 7sim;12 at.% under these conditions. The effects of cobalt content on the CoHAp powders were investigated using ICP emission spectroscopy, particle size analysis, transmission electron microscopy (TEM) and high-resolution transmission electron microscopy (HRTEM) analyses as well as X-ray powder diffraction (XRPD) including Rietveld analysis. According to XRPD, all the materials are single-phase HAp and CoHAp of low crystallinity. Rietveld analysis shows that Co enrichment causes the c cell parameter to decrease at a faster rate than the a cell parameter. A microstructural analysis showed anisotropic X-ray line broadening due to crystallite size reduction. In CoHAp there is significant crystal elongation in [001], and the average size decreases with increasing cobalt content. The crystallite morphology transforms from rod-like for the pure HAp to lamellae at the highest degree of Co substitution. The results of Rietveld refinement (symmetry, size and morphology of the crystallites) were confirmed by TEM and HRTEM analysis. © 2010 International Union of Crystallography. Printed in Singapore-all rights reserved.
PB  - Chester: International Union of Crystallography
T2  - Journal of Applied Crystallography
T1  - Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing
SP  - 320
EP  - 327
VL  - 43
IS  - 2
DO  - 10.1107/S0021889809051395
UR  - https://hdl.handle.net/21.15107/rcub_dais_3428
ER  - 
@article{
author = "Veselinović, Ljiljana and Karanović, Ljiljana and Stojanović, Zoran S. and Bračko, Ines and Marković, Smilja and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
abstract = "A series of cobalt-exchanged hydroxyapatite (CoHAp) powders with different Ca/Co ratios and nominal unit-cell contents Ca10-x Cox (PO4)6(OH)2, x = 0, 0.5, 1.0, 1.5 and 2.0, were synthesized by hydrothermal treatment of a precipitate at 473 K for 8 h. Based on ICP (inductively coupled plasma) emission spectroscopy analysis, it was established that the maximum amount of cobalt incorporation saturated at 7sim;12 at.% under these conditions. The effects of cobalt content on the CoHAp powders were investigated using ICP emission spectroscopy, particle size analysis, transmission electron microscopy (TEM) and high-resolution transmission electron microscopy (HRTEM) analyses as well as X-ray powder diffraction (XRPD) including Rietveld analysis. According to XRPD, all the materials are single-phase HAp and CoHAp of low crystallinity. Rietveld analysis shows that Co enrichment causes the c cell parameter to decrease at a faster rate than the a cell parameter. A microstructural analysis showed anisotropic X-ray line broadening due to crystallite size reduction. In CoHAp there is significant crystal elongation in [001], and the average size decreases with increasing cobalt content. The crystallite morphology transforms from rod-like for the pure HAp to lamellae at the highest degree of Co substitution. The results of Rietveld refinement (symmetry, size and morphology of the crystallites) were confirmed by TEM and HRTEM analysis. © 2010 International Union of Crystallography. Printed in Singapore-all rights reserved.",
publisher = "Chester: International Union of Crystallography",
journal = "Journal of Applied Crystallography",
title = "Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing",
pages = "320-327",
volume = "43",
number = "2",
doi = "10.1107/S0021889809051395",
url = "https://hdl.handle.net/21.15107/rcub_dais_3428"
}
Veselinović, L., Karanović, L., Stojanović, Z. S., Bračko, I., Marković, S., Ignjatović, N.,& Uskoković, D.. (2010). Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. in Journal of Applied Crystallography
Chester: International Union of Crystallography., 43(2), 320-327.
https://doi.org/10.1107/S0021889809051395
https://hdl.handle.net/21.15107/rcub_dais_3428
Veselinović L, Karanović L, Stojanović ZS, Bračko I, Marković S, Ignjatović N, Uskoković D. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. in Journal of Applied Crystallography. 2010;43(2):320-327.
doi:10.1107/S0021889809051395
https://hdl.handle.net/21.15107/rcub_dais_3428 .
Veselinović, Ljiljana, Karanović, Ljiljana, Stojanović, Zoran S., Bračko, Ines, Marković, Smilja, Ignjatović, Nenad, Uskoković, Dragan, "Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing" in Journal of Applied Crystallography, 43, no. 2 (2010):320-327,
https://doi.org/10.1107/S0021889809051395 .,
https://hdl.handle.net/21.15107/rcub_dais_3428 .
56
54
57

FTIR study of biological hydroxyapatite

Marković, Smilja; Veselinović, Ljiljana; Uskoković, Dragan

(2010)

TY  - CONF
AU  - Marković, Smilja
AU  - Veselinović, Ljiljana
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/244
AB  - Poster presentation at the PHYSICAL CHEMISTRY 2010. 10th International Conference on Fundamental and Applied. Aspects of Physical Chemistry, Belgrade, Serbia, September 21-24, 2010
T1  - FTIR study of biological hydroxyapatite
UR  - https://hdl.handle.net/21.15107/rcub_dais_244
ER  - 
@conference{
author = "Marković, Smilja and Veselinović, Ljiljana and Uskoković, Dragan",
year = "2010",
abstract = "Poster presentation at the PHYSICAL CHEMISTRY 2010. 10th International Conference on Fundamental and Applied. Aspects of Physical Chemistry, Belgrade, Serbia, September 21-24, 2010",
title = "FTIR study of biological hydroxyapatite",
url = "https://hdl.handle.net/21.15107/rcub_dais_244"
}
Marković, S., Veselinović, L.,& Uskoković, D.. (2010). FTIR study of biological hydroxyapatite. .
https://hdl.handle.net/21.15107/rcub_dais_244
Marković S, Veselinović L, Uskoković D. FTIR study of biological hydroxyapatite. 2010;.
https://hdl.handle.net/21.15107/rcub_dais_244 .
Marković, Smilja, Veselinović, Ljiljana, Uskoković, Dragan, "FTIR study of biological hydroxyapatite" (2010),
https://hdl.handle.net/21.15107/rcub_dais_244 .

Crystallographic Information for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327

Veselinović, Ljiljana; Karanović, Ljiljana; Bračko, Ines; Marković, Smilja; Ignjatović, Nenad; Uskoković, Dragan

(2010)

TY  - DATA
AU  - Veselinović, Ljiljana
AU  - Karanović, Ljiljana
AU  - Bračko, Ines
AU  - Marković, Smilja
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3440
AB  - Crystallographic Information File contains datablocks HAp, Co5HAp, Co10HAp, Co15HAp, Co20HAp
T2  - Journal of Applied Crystallography
T1  - Crystallographic Information for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327
VL  - 43
UR  - https://hdl.handle.net/21.15107/rcub_dais_3440
ER  - 
@misc{
author = "Veselinović, Ljiljana and Karanović, Ljiljana and Bračko, Ines and Marković, Smilja and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
abstract = "Crystallographic Information File contains datablocks HAp, Co5HAp, Co10HAp, Co15HAp, Co20HAp",
journal = "Journal of Applied Crystallography",
title = "Crystallographic Information for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327",
volume = "43",
url = "https://hdl.handle.net/21.15107/rcub_dais_3440"
}
Veselinović, L., Karanović, L., Bračko, I., Marković, S., Ignjatović, N.,& Uskoković, D.. (2010). Crystallographic Information for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327. in Journal of Applied Crystallography, 43.
https://hdl.handle.net/21.15107/rcub_dais_3440
Veselinović L, Karanović L, Bračko I, Marković S, Ignjatović N, Uskoković D. Crystallographic Information for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327. in Journal of Applied Crystallography. 2010;43.
https://hdl.handle.net/21.15107/rcub_dais_3440 .
Veselinović, Ljiljana, Karanović, Ljiljana, Bračko, Ines, Marković, Smilja, Ignjatović, Nenad, Uskoković, Dragan, "Crystallographic Information for the article Veselinović, L., Karanović, L., Stojanović, Z., Bračko, I., Marković, S., Ignjatović, N., Uskoković, D., 2010. Crystal structure of cobalt-substituted calcium hydroxyapatite nanopowders prepared by hydrothermal processing. Journal of Applied Crystallography 43, 320–327" in Journal of Applied Crystallography, 43 (2010),
https://hdl.handle.net/21.15107/rcub_dais_3440 .

FTIR study of biological hydroxyapatite

Marković, Smilja; Veselinović, Ljiljana; Uskoković, Dragan

(Belgrade : Society of Physical Chemists of Serbia, 2010)

TY  - CONF
AU  - Marković, Smilja
AU  - Veselinović, Ljiljana
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3507
AB  - In this study Fourier transform infrared (FTIR) spectroscopy was used to resolve setting of carbonate ions in biological hydroxyapatite (BHAp). Even though preliminary XRPD results indicate that BHAp is B-type carbonated hydroxyapatite, the detailed FTIR spectroscopy analysis show that carbonate ions substitute both phosphate and hydroxyl ions in the crystal structure of BHAp, representing a mixed AB-type.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - Physical Chemistry 2010 : proceedings. Vol. 1 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade
T1  - FTIR study of biological hydroxyapatite
SP  - 75
EP  - 77
UR  - https://hdl.handle.net/21.15107/rcub_dais_3507
ER  - 
@conference{
author = "Marković, Smilja and Veselinović, Ljiljana and Uskoković, Dragan",
year = "2010",
abstract = "In this study Fourier transform infrared (FTIR) spectroscopy was used to resolve setting of carbonate ions in biological hydroxyapatite (BHAp). Even though preliminary XRPD results indicate that BHAp is B-type carbonated hydroxyapatite, the detailed FTIR spectroscopy analysis show that carbonate ions substitute both phosphate and hydroxyl ions in the crystal structure of BHAp, representing a mixed AB-type.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "Physical Chemistry 2010 : proceedings. Vol. 1 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade",
title = "FTIR study of biological hydroxyapatite",
pages = "75-77",
url = "https://hdl.handle.net/21.15107/rcub_dais_3507"
}
Marković, S., Veselinović, L.,& Uskoković, D.. (2010). FTIR study of biological hydroxyapatite. in Physical Chemistry 2010 : proceedings. Vol. 1 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade
Belgrade : Society of Physical Chemists of Serbia., 75-77.
https://hdl.handle.net/21.15107/rcub_dais_3507
Marković S, Veselinović L, Uskoković D. FTIR study of biological hydroxyapatite. in Physical Chemistry 2010 : proceedings. Vol. 1 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade. 2010;:75-77.
https://hdl.handle.net/21.15107/rcub_dais_3507 .
Marković, Smilja, Veselinović, Ljiljana, Uskoković, Dragan, "FTIR study of biological hydroxyapatite" in Physical Chemistry 2010 : proceedings. Vol. 1 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade (2010):75-77,
https://hdl.handle.net/21.15107/rcub_dais_3507 .

Electrical properties of barium titanate stannate functionally graded materials

Marković, Smilja; Jovalekić, Čedomir; Veselinović, Ljiljana; Mentus, Slavko; Uskoković, Dragan

(Elsevier, 2010)

TY  - JOUR
AU  - Marković, Smilja
AU  - Jovalekić, Čedomir
AU  - Veselinović, Ljiljana
AU  - Mentus, Slavko
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3425
AB  - Barium titanate stannate (BTS) functionally graded materials (FGMs) with different tin/titanium concentration gradient were prepared by the powder-stacking method and uniaxially pressing process, followed by sintering. Impedance spectroscopy (IS) was used to determine the electrical characteristics of FGMs and ingredient BTS ceramics, as well as to distinguish the grain-interior and grain boundary resistivity of the ceramics. Activation energies of FGMs and ingredients were calculated. It has been established that for BTS ceramics the activation energy deduced from grain-interior conductivity (0.73-0.75 eV) is defined by chemical composition, while activation energy for grain boundary conductivity (1.07-1.25 eV) is influenced by microstructural development (density and average grain size). Furthermore, for FGMs, activation energy for grain-interior conductivity kept the intrinsic properties (0.74-0.78 eV) and did not depend on tin/titanium concentration gradient, while activation energy (1.03-1.29 eV) for grain boundary was determined by the microstructural gradient. No point dissipation was observed by IS, accordingly, no insulator interfaces (cracks and/or delamination) between graded layers were detected. © 2009 Elsevier Ltd. All rights reserved.
PB  - Elsevier
T2  - Journal of the European Ceramic Society
T1  - Electrical properties of barium titanate stannate functionally graded materials
SP  - 1427
EP  - 1435
VL  - 30
IS  - 6
DO  - 10.1016/j.jeurceramsoc.2009.10.020
UR  - https://hdl.handle.net/21.15107/rcub_dais_3425
ER  - 
@article{
author = "Marković, Smilja and Jovalekić, Čedomir and Veselinović, Ljiljana and Mentus, Slavko and Uskoković, Dragan",
year = "2010",
abstract = "Barium titanate stannate (BTS) functionally graded materials (FGMs) with different tin/titanium concentration gradient were prepared by the powder-stacking method and uniaxially pressing process, followed by sintering. Impedance spectroscopy (IS) was used to determine the electrical characteristics of FGMs and ingredient BTS ceramics, as well as to distinguish the grain-interior and grain boundary resistivity of the ceramics. Activation energies of FGMs and ingredients were calculated. It has been established that for BTS ceramics the activation energy deduced from grain-interior conductivity (0.73-0.75 eV) is defined by chemical composition, while activation energy for grain boundary conductivity (1.07-1.25 eV) is influenced by microstructural development (density and average grain size). Furthermore, for FGMs, activation energy for grain-interior conductivity kept the intrinsic properties (0.74-0.78 eV) and did not depend on tin/titanium concentration gradient, while activation energy (1.03-1.29 eV) for grain boundary was determined by the microstructural gradient. No point dissipation was observed by IS, accordingly, no insulator interfaces (cracks and/or delamination) between graded layers were detected. © 2009 Elsevier Ltd. All rights reserved.",
publisher = "Elsevier",
journal = "Journal of the European Ceramic Society",
title = "Electrical properties of barium titanate stannate functionally graded materials",
pages = "1427-1435",
volume = "30",
number = "6",
doi = "10.1016/j.jeurceramsoc.2009.10.020",
url = "https://hdl.handle.net/21.15107/rcub_dais_3425"
}
Marković, S., Jovalekić, Č., Veselinović, L., Mentus, S.,& Uskoković, D.. (2010). Electrical properties of barium titanate stannate functionally graded materials. in Journal of the European Ceramic Society
Elsevier., 30(6), 1427-1435.
https://doi.org/10.1016/j.jeurceramsoc.2009.10.020
https://hdl.handle.net/21.15107/rcub_dais_3425
Marković S, Jovalekić Č, Veselinović L, Mentus S, Uskoković D. Electrical properties of barium titanate stannate functionally graded materials. in Journal of the European Ceramic Society. 2010;30(6):1427-1435.
doi:10.1016/j.jeurceramsoc.2009.10.020
https://hdl.handle.net/21.15107/rcub_dais_3425 .
Marković, Smilja, Jovalekić, Čedomir, Veselinović, Ljiljana, Mentus, Slavko, Uskoković, Dragan, "Electrical properties of barium titanate stannate functionally graded materials" in Journal of the European Ceramic Society, 30, no. 6 (2010):1427-1435,
https://doi.org/10.1016/j.jeurceramsoc.2009.10.020 .,
https://hdl.handle.net/21.15107/rcub_dais_3425 .
17
16
19

Sinteza, karakterizacija i primena funkcionalizovanih ugljeničnih nanocevi

Vuković, Goran

(Belgrade : University of Belgrade, Faculty of Technology and Metallurgy, 2010)

TY  - THES
AU  - Vuković, Goran
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/82
AB  - U ovoj doktorskoj disertaciji opisana je kovalentna funkcionalizacija višeslojnih ugljeničnih nanocevi (multi-walled carbon nanotubes, MWCNT) pomoću amina. Funkcionalizacija je izvršena hemijskom modifikacijom karboksilnih grupa koje su uvedene na površinu nanocevi metodom oksidacije u smeši koncentrovanih kiselina. MWCNT su funkcionalizovane etilendiaminom (EDA), 1,6-heksandiaminom (HDA), dietilentriaminom (DETA), trietilentetraaminom (TETA) i 1,4-fenilendiaminom (PDA) pomoću O-(7-azabenzotriazol-1-il)-N,N,N',N'-tetrametiluronium heksafluorofosfata (N-HATU) i N,Ndiizopropiletilamina (DIEA). Kuplujući agens N-HATU omogućuje veću brzinu reakcije funkcionalizacije u odnosu na postojeće metode sinteze amida. Dobijeni uzorci su karakterisani različitim tehnikama, kao što su: FTIR, XRD, elementarna analiza, TGA, SEM, TEM, STM, UV-vis spektroskopija i ciklična voltametrija. MWCNT funkcionalizovane sa PDA i EDA poseduju najbolja disperzibilna i elektrohemijska svojstva. Funkcionalizovane MWCNT, u koncentracijama od 1 do 50 μg/ml, nisu citotoksične za fibroblastnu, L929 ćelijsku liniju. Međutim, koncentracije MWCNT veće od 10 μg/ml smanjuju rast ćelija i u tom smislu ovaj nalaz je u pozitivnoj korelaciji sa stepenom njihove internalizacije od strane L929 ćelija. U okviru ove disertacije prikazano je uklanjanje kadmijuma iz vodenih rastvora pomoću netretiranih višeslojnih ugljeničnih nanocevi (n-MWCNT), oksidovanih (o-MWCNT) i etilendiaminom funkcionalizovanih (e-MWCNT). U šaržnim uslovima ispitan je uticaj pH vrednosti rastvora, kontaktnog vremena, početne koncentracije metala i temperature na sorpciju Cd2+ jona na n-MWCNT, o-MWCNT i e-MWCNT. Adsorpcija Cd2+ jona na o-MWCNT i e-MWCNT izrazito zavisi od pH vrednosti rastvora. Vremenski zavisna adsorpcija Cd2+ jona na n-MWCNT, o-MWCNT i e-MWCNT opisana je pomoću kinetičkog modela pseudo drugog reda. Model Langmuirove izoterme najbolje fituje dobijene eksperimentalne ravnotežne podatke. Maksimalni kapacitet od 25,7 mg/g, na 45 °C, dobijen je za e-MWCNT.
Termodinamički parametri su takođe, izračunati za adsorpciju Cd2+ jona na n-MWCNT, o-MWCNT i e-MWCNT i rezultati pokazuju da je proces adsorpcije spontan i endoterman. Kovalentna amino-funkcionalizacija MWCNT prikazana je kao pogodan metod za poboljšanje mogućnosti daljeg procesiranja MWCNT. Upotrebom funkcionalizovanih nanocevi dobijeni su homogeni i transparentni kompoziti, na bazi MWCNT i poli(metal metakrilata) (PMMA). Kovalentna veza, koja se formira između amino-funkcionalizovanih MWCNT i PMMA, poboljšava disperziju MWCNT u polimeru kao i električna i mehanička svojstva kompozita.
Komercijalne višeslojne ugljenične nanocevi (Sigma–Aldrich i Sun Nanotech) i ugljenik XC-72R (Vulcan®, Cabot Corporation) ispitivani su netretirani i oksidovani. Rezultati elektrohemijske karakterizacije pokazuju da se posle oksidacije povećava elektrohemijski aktivna površina i kapacitivnost ugljeničnih uzoraka, kao i da se poboljšavaju svojstva prenosa naelektrisanja koja su ispitivana na osnovu reverzibilnosti Fe(CN)63–/Fe(CN)64– reakcije. Ugljenične nanocevi pokazuju bolja elektrohemijska svojstva u odnosu na ugljenik XC-72R. Morfologija ugljeničnih nanocevi ima veliki uticaj na elektrohemijska svojstva. Nanocevi sa naboranim zidovima pokazale su bolja svojstva prenosa naelektrisanja i veću pseudokapacitivnost od nanocevi sa glatkim zidovima, što je posledica većeg udela ivica grafena i defektnih mesta u ugljeničnom materijalu. Iz tog razloga su za dalju modifikaciju korišćene oksidovane nanocevi proizvođača Sigma–Aldrich.
Elektrohemijska svojstva višeslojnih ugljeničnih nanocevi modifikovanih etilendiaminom ispitivana su cikličnom voltametrijom i upoređena su sa oksidovanim ugljeničnim nanocevima. Pokazano je da modifikacija ugljeničnih nanocevi etilendiaminom dovodi do značajnog opadanja elektrohemijske aktivnosti grupa koje sadrže kiseonik, što je posledica reakcije sa etilendiaminom. Nakon modifikacije vidno je smanjenje prividne kapacitivnosti, kao i blago smanjenje svojstava prenosa naelektrisanja koja su ispitivana na osnovu reverzibilnosti Fe(CN)63–/Fe(CN)64– reakcije. Ovo je prouzrokovano smanjenjem pristupačnosti elektrolita ukupnoj površini ugljeničnih nanocevi modifikovanih etilendiaminom.
Na oksidovane i etilendiaminom modifikovane ugljenične nanocevi nanesene su nanočestice Pt koje su sintetizovane poliolnom metodom uz pomoć mikrotalasa. Količina adsorbovanih Pt nanočestica na e-MWCNT značajno je veća nego na oksidovanim nanocevima. Raspodela Pt nanočestica na EDA-modifikovanim ugljeničnim nanocevima je homogena, a srednja veličina čestica iznosi 2,5 ± 0,5 nm. Elektrohemijska merenja su pokazala da Pt nanočestice na nosaču od e-MWCNT imaju visoku vrednost elektrohemijski aktivne površine. 
U okviru disertacije izvršena je modifikacija MWCNT dapsonom koji se koristi kao anti-mikrobski i anti-zapaljenski lek. Dapsonom-modifikovane višeslojne ugljenične nanocevi (dap-MWCNT) koje su disperzibilne u vodi, pripremljene su hemijskom modifikacijom karboksilnih grupa na površini nanocevi koristeći N-HATU i DIEA. Modifikacija je potvrđena različitim tehnikama, kao što su: FTIR, TEM, TGA i elementarna analiza. Biološki efekat dap-MWCNT testiran je na makrofagama izolovanim iz peritoneuma (PMØ) pacova. Konfokalnom laserskom mikroskopijom i protočnom citometrijom pokazano je da su PMØ brzo fagocitovale dap-MWCNT kao i oksidovane (o)-MWCNT koje su upotrebljene kao kontrolni uzorak. Viabilnost PMØ nije promenjena ni sa dap-MWCNT pri malim koncentracijama (50 μg/ml i manje), kao ni sa o-MWCNT pri ekvivalentnim koncentracijama, dok veće koncentracije (50 μg/ml i više) izazivaju programiranu ćelijsku smrt, apoptozu. Apoptoza PMØ koja je izazvana pomoću kontrolnih uzoraka o-MWCNT je veća od apoptoze izazvane sa dap-MWCNT i povezana je sa pojavom oksidativnog stresa. Nasuprot tome, dap-MWCNT nisu aktivirale oksidativni stres, već su prouzrokovale apoptozu PMØ, i to najviše nakon produžene kultivacije od 3 dana. Ekvivalentne koncentracije rastvornog dapsona, iako su izazvale oksidativni stres, nisu indukovale apoptozu. Celokupni rezultat pokazuje kompleksnost dap-MWCNT/PMØ interakcija i sugeriše da se ovaj konjugat može ispitati za tretman unutar-ćelijskih mikroorganizama koji su osetljivi na dapson kao i za zapaljenske procese kod kojih se dapson koristi kao lek.
AB  - Since their discovery in 1991 by Iijima, carbon nanotubes (CNTs) have attracted great interest in most areas of science and engineering due to their unique physical and chemical properties, which enable them to be applied for a wide range of applications. However, the application of CNTs has been largely hampered by their poor dispersion into solvents or polymers due to the strong intermolecular van der Waals interactions among the nanotubes, which can lead to the formation of aggregates. A common technique to improve dispersion and realize such a great capability of CNTs is through chemical functionalization, which enables chemical covalent or non-covalent bonding between the CNTs and material of interest. The covalent side-wall modifications of nanotubes, in general, include: (i) amidation or esterification of carboxylated CNTs, (ii) side-wall covalent attachment of functional groups directly to the pristine CNTs. Among them, amino-functionalized CNTs have been investigated because amino group has a high reactivity, and can react with many chemicals, such as polymers, and biological components. Amino-functionalization was also employed and studied in this work. Modified CNTs were examined toward different applications described below.
Surface functionalization of multi-walled carbon nanotubes (MWCNTs), with amino groups via chemical modification of carboxyl groups introduced on the nanotube surface, using O-(7-azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate (NHATU) and N,N-diisopropylethylamine (DIEA) was reported. The N-HATU coupling agent provides faster reaction rate and the reaction occurs at lower temperature compared to amidation and acylation-amidation chemistry. The amines, ethylenediamine (EDA), 1,6-hexanediamine (HDA), diethylenetriamine (DETA), triethylenetetramine (TETA) and 1,4-phenylenediamine (PDA) were used. The resulting materials were characterized with different techniques such as FTIR, XRD, elemental analysis, TGA, SEM, TEM, STM, UV-vis spectroscopy and cyclic voltammetry. MWCNTs functionalized with PDA and EDA posses the best dispersibility and electron transfer properties in comparison to the others amines. Functionalized MWCNTs, at the concentrations between 1 and 50 μg/ml, were not cytotoxic for the fibroblast L929 cell line. However, the concentrations of MWCNTs higher of 10 μg/ml reduced cell growth and this effect correlated positively with the degree of their uptake by L929 cells.
In batch tests, the influences of solution pH, contact time, initial metal ion concentration and temperature on the sorption of Cd2+ ions onto raw MWCNTs (raw-MWCNT), oxidized MWCNTs (o-MWCNT) and EDA-functionalized MWCNTs (e-MWCNT) were studied. The adsorption of Cd2+ ions by o-MWCNT and e-MWCNT was strongly pH-dependent. The time dependent Cd2+ sorption onto raw-MWCNT, o-MWCNT and e-MWCNT can be described by a pseudo-second-order kinetic model. The Langmuir isotherm model agrees well with the equilibrium experimental data. The maximum capacity was obtained for e-MWCNT, 25.7 mg/g, at 45 °C. The thermodynamic parameters were also deduced for the adsorption of Cd2+ ions on raw-MWCNT, o-MWCNT and e-MWCNT and the results showed that the adsorption was spontaneous and endothermic.
In this study was shown that covalent amino-functionalization of MWCNTs was a powerful method for enhancing the ability to process MWCNTs and facilitating the preparation of homogenous, coherent and transparent MWCNT/Poly(methyl methacrylate) (PMMA) composites. Covalent bond formation between amino-functionalized MWCNTs and PMMA enhanced the MWCNTs dispersion in polymer and improved electrical conductivity and mechanical properties of the composite.
Two samples of commercial MWCNTs (Sigma–Aldrich and Sun Nanotech) and a sample of carbon black (Vulcan XC-72R) were investigated in raw state and after the oxidation in nitric and sulfuric acid by ultrasound agitation. Atomic force microscopy revealed that oxidized Sigma–Aldrich nanotubes are straight with corrugated walls (bamboolike structure), while Sun Nanotech nanotubes are tortuous with smooth walls. Fourier transform infrared spectroscopy showed that abundance of oxygen containing functional groups was formed on both Sigma–Aldrich and Sun Nanotech carbon nanotubes, as well as on carbon black surfaces. Electrochemical properties were studied by cyclic voltammetry. It was found that the electrochemically active surface area of all carbon samples is expanded, charge storage ability is enhanced and the electron-transfer kinetics, probed by Fe(CN)63–/Fe(CN)64– redox couple, is promoted upon activation. The characteristics of MWCNTs were superior to carbon black. Morphology of the MWCNTs was found to be important; nanotubes with corrugated walls showed faster electron-transfer and pseudocapacitive redox kinetics than nanotubes with smooth walls. This was explained by the higher proportion of edge and defect sites, which are known as more electrochemically active than the walls of uniform grapheme structure. For this reason, oxidized MWCNTs obtained from Sigma-Aldrich were used for further modification. Electrochemical properties of EDA modified MWCNTs have been examined by using cyclic voltammetry in 0.1 M H2SO4 and 1.0 M KCl and compared with the oxidized MWCNTs. It was found that the modification by EDA leads to the significant decrease in activity of electrochemicaly active oxygen containing groups that was caused by amine grafting processes. The decrease in apparent capacitance and in the electron-transfer kinetics, probed by Fe(CN)63–/Fe(CN)64– redox couple, was observed upon modification. These were caused by the decrease in accessibility of electrolyte to overall surface area of EDA modified carbon nanotubes. MWCNTs, oxidized and EDA functionalized, were used as a supporting material for Pt nanoparticles prepared by the microwave-assisted polyol method. The Pt loading of Pt/o-MWCNT was only 2 mass % while the loading of Pt/e-MWCNT was 20 mass%. Much higher efficiency of Pt deposition on e-MWCNTs than on o-MWCNTs was ascribed to the shift in pHpzc value of the CNTs surface from 2.43 to 5.91 upon modification by EDA. The investigation by transmission electron microscopy (TEM) revealed that the mean diameter of Pt particles in Pt/e-MWCNT is 2.5  0.5 nm and that their distribution on the support is homogenous with no evidence of pronounced particles agglomeration. Cyclic voltammetry of Pt/e-MWCNT thin film indicated clean Pt surface with well-resolved peaks characteristic for polycrystalline Pt. Dapsone is an anti-microbial and anti-inflammatory drug. Water-dispersible dapsonemodified multi-wall carbon nanotubes (dap-MWCNTs) were prepared by chemical modification of the carboxyl groups introduced on the surface of the nanotubes using O-(7-azabenzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate (N-HATU) and N,N-diisopropylethylamine (DIEA). The modification was confirmed by Fourier-transform infrared spectroscopy, transmission election microscopy and thermogravimetric analysis. The biological effect of dap-MWCNTs was tested using rat peritoneal macrophages (PMØ). By confocal laser microscopy and flow cytometry, it was shown that the dap-MWCNTs were rapidly ingested by PMØ as were the control, oxidized o-MWCNTs. Neither dap-MWCNTs at lower concentrations (up to 50 μg/ml), nor o-MWCNTs, at equivalent concentrations, respectively affected the viability of PMØ, while higher concentrations triggered apoptosis. Apoptosis of PMØ induced by the control, o-MWCNTs, was higher than that induced by dap-MWCNTs and it correlated with the induction of oxidative stress. In contrast, dap-MWCNTs did not trigger oxidative stress but caused apoptosis of PMØ predominantly after prolonged cultivation (3 days). Although equivalent concentrations of soluble dapsone induced oxidative stress, they were anti-apoptotic. Cumulatively, the obtained results show the complexity of dap-MWCNT/PMØ interactions and suggest that this complex could be investigated for the treatment of dapsone-sensitive intracellular microorganisms or inflammatory diseases responding to dapsone therapy.
PB  - Belgrade : University of Belgrade, Faculty of Technology and Metallurgy
T1  - Sinteza, karakterizacija i primena funkcionalizovanih ugljeničnih nanocevi
UR  - https://hdl.handle.net/21.15107/rcub_dais_82
ER  - 
@phdthesis{
author = "Vuković, Goran",
year = "2010",
abstract = "U ovoj doktorskoj disertaciji opisana je kovalentna funkcionalizacija višeslojnih ugljeničnih nanocevi (multi-walled carbon nanotubes, MWCNT) pomoću amina. Funkcionalizacija je izvršena hemijskom modifikacijom karboksilnih grupa koje su uvedene na površinu nanocevi metodom oksidacije u smeši koncentrovanih kiselina. MWCNT su funkcionalizovane etilendiaminom (EDA), 1,6-heksandiaminom (HDA), dietilentriaminom (DETA), trietilentetraaminom (TETA) i 1,4-fenilendiaminom (PDA) pomoću O-(7-azabenzotriazol-1-il)-N,N,N',N'-tetrametiluronium heksafluorofosfata (N-HATU) i N,Ndiizopropiletilamina (DIEA). Kuplujući agens N-HATU omogućuje veću brzinu reakcije funkcionalizacije u odnosu na postojeće metode sinteze amida. Dobijeni uzorci su karakterisani različitim tehnikama, kao što su: FTIR, XRD, elementarna analiza, TGA, SEM, TEM, STM, UV-vis spektroskopija i ciklična voltametrija. MWCNT funkcionalizovane sa PDA i EDA poseduju najbolja disperzibilna i elektrohemijska svojstva. Funkcionalizovane MWCNT, u koncentracijama od 1 do 50 μg/ml, nisu citotoksične za fibroblastnu, L929 ćelijsku liniju. Međutim, koncentracije MWCNT veće od 10 μg/ml smanjuju rast ćelija i u tom smislu ovaj nalaz je u pozitivnoj korelaciji sa stepenom njihove internalizacije od strane L929 ćelija. U okviru ove disertacije prikazano je uklanjanje kadmijuma iz vodenih rastvora pomoću netretiranih višeslojnih ugljeničnih nanocevi (n-MWCNT), oksidovanih (o-MWCNT) i etilendiaminom funkcionalizovanih (e-MWCNT). U šaržnim uslovima ispitan je uticaj pH vrednosti rastvora, kontaktnog vremena, početne koncentracije metala i temperature na sorpciju Cd2+ jona na n-MWCNT, o-MWCNT i e-MWCNT. Adsorpcija Cd2+ jona na o-MWCNT i e-MWCNT izrazito zavisi od pH vrednosti rastvora. Vremenski zavisna adsorpcija Cd2+ jona na n-MWCNT, o-MWCNT i e-MWCNT opisana je pomoću kinetičkog modela pseudo drugog reda. Model Langmuirove izoterme najbolje fituje dobijene eksperimentalne ravnotežne podatke. Maksimalni kapacitet od 25,7 mg/g, na 45 °C, dobijen je za e-MWCNT.
Termodinamički parametri su takođe, izračunati za adsorpciju Cd2+ jona na n-MWCNT, o-MWCNT i e-MWCNT i rezultati pokazuju da je proces adsorpcije spontan i endoterman. Kovalentna amino-funkcionalizacija MWCNT prikazana je kao pogodan metod za poboljšanje mogućnosti daljeg procesiranja MWCNT. Upotrebom funkcionalizovanih nanocevi dobijeni su homogeni i transparentni kompoziti, na bazi MWCNT i poli(metal metakrilata) (PMMA). Kovalentna veza, koja se formira između amino-funkcionalizovanih MWCNT i PMMA, poboljšava disperziju MWCNT u polimeru kao i električna i mehanička svojstva kompozita.
Komercijalne višeslojne ugljenične nanocevi (Sigma–Aldrich i Sun Nanotech) i ugljenik XC-72R (Vulcan®, Cabot Corporation) ispitivani su netretirani i oksidovani. Rezultati elektrohemijske karakterizacije pokazuju da se posle oksidacije povećava elektrohemijski aktivna površina i kapacitivnost ugljeničnih uzoraka, kao i da se poboljšavaju svojstva prenosa naelektrisanja koja su ispitivana na osnovu reverzibilnosti Fe(CN)63–/Fe(CN)64– reakcije. Ugljenične nanocevi pokazuju bolja elektrohemijska svojstva u odnosu na ugljenik XC-72R. Morfologija ugljeničnih nanocevi ima veliki uticaj na elektrohemijska svojstva. Nanocevi sa naboranim zidovima pokazale su bolja svojstva prenosa naelektrisanja i veću pseudokapacitivnost od nanocevi sa glatkim zidovima, što je posledica većeg udela ivica grafena i defektnih mesta u ugljeničnom materijalu. Iz tog razloga su za dalju modifikaciju korišćene oksidovane nanocevi proizvođača Sigma–Aldrich.
Elektrohemijska svojstva višeslojnih ugljeničnih nanocevi modifikovanih etilendiaminom ispitivana su cikličnom voltametrijom i upoređena su sa oksidovanim ugljeničnim nanocevima. Pokazano je da modifikacija ugljeničnih nanocevi etilendiaminom dovodi do značajnog opadanja elektrohemijske aktivnosti grupa koje sadrže kiseonik, što je posledica reakcije sa etilendiaminom. Nakon modifikacije vidno je smanjenje prividne kapacitivnosti, kao i blago smanjenje svojstava prenosa naelektrisanja koja su ispitivana na osnovu reverzibilnosti Fe(CN)63–/Fe(CN)64– reakcije. Ovo je prouzrokovano smanjenjem pristupačnosti elektrolita ukupnoj površini ugljeničnih nanocevi modifikovanih etilendiaminom.
Na oksidovane i etilendiaminom modifikovane ugljenične nanocevi nanesene su nanočestice Pt koje su sintetizovane poliolnom metodom uz pomoć mikrotalasa. Količina adsorbovanih Pt nanočestica na e-MWCNT značajno je veća nego na oksidovanim nanocevima. Raspodela Pt nanočestica na EDA-modifikovanim ugljeničnim nanocevima je homogena, a srednja veličina čestica iznosi 2,5 ± 0,5 nm. Elektrohemijska merenja su pokazala da Pt nanočestice na nosaču od e-MWCNT imaju visoku vrednost elektrohemijski aktivne površine. 
U okviru disertacije izvršena je modifikacija MWCNT dapsonom koji se koristi kao anti-mikrobski i anti-zapaljenski lek. Dapsonom-modifikovane višeslojne ugljenične nanocevi (dap-MWCNT) koje su disperzibilne u vodi, pripremljene su hemijskom modifikacijom karboksilnih grupa na površini nanocevi koristeći N-HATU i DIEA. Modifikacija je potvrđena različitim tehnikama, kao što su: FTIR, TEM, TGA i elementarna analiza. Biološki efekat dap-MWCNT testiran je na makrofagama izolovanim iz peritoneuma (PMØ) pacova. Konfokalnom laserskom mikroskopijom i protočnom citometrijom pokazano je da su PMØ brzo fagocitovale dap-MWCNT kao i oksidovane (o)-MWCNT koje su upotrebljene kao kontrolni uzorak. Viabilnost PMØ nije promenjena ni sa dap-MWCNT pri malim koncentracijama (50 μg/ml i manje), kao ni sa o-MWCNT pri ekvivalentnim koncentracijama, dok veće koncentracije (50 μg/ml i više) izazivaju programiranu ćelijsku smrt, apoptozu. Apoptoza PMØ koja je izazvana pomoću kontrolnih uzoraka o-MWCNT je veća od apoptoze izazvane sa dap-MWCNT i povezana je sa pojavom oksidativnog stresa. Nasuprot tome, dap-MWCNT nisu aktivirale oksidativni stres, već su prouzrokovale apoptozu PMØ, i to najviše nakon produžene kultivacije od 3 dana. Ekvivalentne koncentracije rastvornog dapsona, iako su izazvale oksidativni stres, nisu indukovale apoptozu. Celokupni rezultat pokazuje kompleksnost dap-MWCNT/PMØ interakcija i sugeriše da se ovaj konjugat može ispitati za tretman unutar-ćelijskih mikroorganizama koji su osetljivi na dapson kao i za zapaljenske procese kod kojih se dapson koristi kao lek., Since their discovery in 1991 by Iijima, carbon nanotubes (CNTs) have attracted great interest in most areas of science and engineering due to their unique physical and chemical properties, which enable them to be applied for a wide range of applications. However, the application of CNTs has been largely hampered by their poor dispersion into solvents or polymers due to the strong intermolecular van der Waals interactions among the nanotubes, which can lead to the formation of aggregates. A common technique to improve dispersion and realize such a great capability of CNTs is through chemical functionalization, which enables chemical covalent or non-covalent bonding between the CNTs and material of interest. The covalent side-wall modifications of nanotubes, in general, include: (i) amidation or esterification of carboxylated CNTs, (ii) side-wall covalent attachment of functional groups directly to the pristine CNTs. Among them, amino-functionalized CNTs have been investigated because amino group has a high reactivity, and can react with many chemicals, such as polymers, and biological components. Amino-functionalization was also employed and studied in this work. Modified CNTs were examined toward different applications described below.
Surface functionalization of multi-walled carbon nanotubes (MWCNTs), with amino groups via chemical modification of carboxyl groups introduced on the nanotube surface, using O-(7-azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate (NHATU) and N,N-diisopropylethylamine (DIEA) was reported. The N-HATU coupling agent provides faster reaction rate and the reaction occurs at lower temperature compared to amidation and acylation-amidation chemistry. The amines, ethylenediamine (EDA), 1,6-hexanediamine (HDA), diethylenetriamine (DETA), triethylenetetramine (TETA) and 1,4-phenylenediamine (PDA) were used. The resulting materials were characterized with different techniques such as FTIR, XRD, elemental analysis, TGA, SEM, TEM, STM, UV-vis spectroscopy and cyclic voltammetry. MWCNTs functionalized with PDA and EDA posses the best dispersibility and electron transfer properties in comparison to the others amines. Functionalized MWCNTs, at the concentrations between 1 and 50 μg/ml, were not cytotoxic for the fibroblast L929 cell line. However, the concentrations of MWCNTs higher of 10 μg/ml reduced cell growth and this effect correlated positively with the degree of their uptake by L929 cells.
In batch tests, the influences of solution pH, contact time, initial metal ion concentration and temperature on the sorption of Cd2+ ions onto raw MWCNTs (raw-MWCNT), oxidized MWCNTs (o-MWCNT) and EDA-functionalized MWCNTs (e-MWCNT) were studied. The adsorption of Cd2+ ions by o-MWCNT and e-MWCNT was strongly pH-dependent. The time dependent Cd2+ sorption onto raw-MWCNT, o-MWCNT and e-MWCNT can be described by a pseudo-second-order kinetic model. The Langmuir isotherm model agrees well with the equilibrium experimental data. The maximum capacity was obtained for e-MWCNT, 25.7 mg/g, at 45 °C. The thermodynamic parameters were also deduced for the adsorption of Cd2+ ions on raw-MWCNT, o-MWCNT and e-MWCNT and the results showed that the adsorption was spontaneous and endothermic.
In this study was shown that covalent amino-functionalization of MWCNTs was a powerful method for enhancing the ability to process MWCNTs and facilitating the preparation of homogenous, coherent and transparent MWCNT/Poly(methyl methacrylate) (PMMA) composites. Covalent bond formation between amino-functionalized MWCNTs and PMMA enhanced the MWCNTs dispersion in polymer and improved electrical conductivity and mechanical properties of the composite.
Two samples of commercial MWCNTs (Sigma–Aldrich and Sun Nanotech) and a sample of carbon black (Vulcan XC-72R) were investigated in raw state and after the oxidation in nitric and sulfuric acid by ultrasound agitation. Atomic force microscopy revealed that oxidized Sigma–Aldrich nanotubes are straight with corrugated walls (bamboolike structure), while Sun Nanotech nanotubes are tortuous with smooth walls. Fourier transform infrared spectroscopy showed that abundance of oxygen containing functional groups was formed on both Sigma–Aldrich and Sun Nanotech carbon nanotubes, as well as on carbon black surfaces. Electrochemical properties were studied by cyclic voltammetry. It was found that the electrochemically active surface area of all carbon samples is expanded, charge storage ability is enhanced and the electron-transfer kinetics, probed by Fe(CN)63–/Fe(CN)64– redox couple, is promoted upon activation. The characteristics of MWCNTs were superior to carbon black. Morphology of the MWCNTs was found to be important; nanotubes with corrugated walls showed faster electron-transfer and pseudocapacitive redox kinetics than nanotubes with smooth walls. This was explained by the higher proportion of edge and defect sites, which are known as more electrochemically active than the walls of uniform grapheme structure. For this reason, oxidized MWCNTs obtained from Sigma-Aldrich were used for further modification. Electrochemical properties of EDA modified MWCNTs have been examined by using cyclic voltammetry in 0.1 M H2SO4 and 1.0 M KCl and compared with the oxidized MWCNTs. It was found that the modification by EDA leads to the significant decrease in activity of electrochemicaly active oxygen containing groups that was caused by amine grafting processes. The decrease in apparent capacitance and in the electron-transfer kinetics, probed by Fe(CN)63–/Fe(CN)64– redox couple, was observed upon modification. These were caused by the decrease in accessibility of electrolyte to overall surface area of EDA modified carbon nanotubes. MWCNTs, oxidized and EDA functionalized, were used as a supporting material for Pt nanoparticles prepared by the microwave-assisted polyol method. The Pt loading of Pt/o-MWCNT was only 2 mass % while the loading of Pt/e-MWCNT was 20 mass%. Much higher efficiency of Pt deposition on e-MWCNTs than on o-MWCNTs was ascribed to the shift in pHpzc value of the CNTs surface from 2.43 to 5.91 upon modification by EDA. The investigation by transmission electron microscopy (TEM) revealed that the mean diameter of Pt particles in Pt/e-MWCNT is 2.5  0.5 nm and that their distribution on the support is homogenous with no evidence of pronounced particles agglomeration. Cyclic voltammetry of Pt/e-MWCNT thin film indicated clean Pt surface with well-resolved peaks characteristic for polycrystalline Pt. Dapsone is an anti-microbial and anti-inflammatory drug. Water-dispersible dapsonemodified multi-wall carbon nanotubes (dap-MWCNTs) were prepared by chemical modification of the carboxyl groups introduced on the surface of the nanotubes using O-(7-azabenzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate (N-HATU) and N,N-diisopropylethylamine (DIEA). The modification was confirmed by Fourier-transform infrared spectroscopy, transmission election microscopy and thermogravimetric analysis. The biological effect of dap-MWCNTs was tested using rat peritoneal macrophages (PMØ). By confocal laser microscopy and flow cytometry, it was shown that the dap-MWCNTs were rapidly ingested by PMØ as were the control, oxidized o-MWCNTs. Neither dap-MWCNTs at lower concentrations (up to 50 μg/ml), nor o-MWCNTs, at equivalent concentrations, respectively affected the viability of PMØ, while higher concentrations triggered apoptosis. Apoptosis of PMØ induced by the control, o-MWCNTs, was higher than that induced by dap-MWCNTs and it correlated with the induction of oxidative stress. In contrast, dap-MWCNTs did not trigger oxidative stress but caused apoptosis of PMØ predominantly after prolonged cultivation (3 days). Although equivalent concentrations of soluble dapsone induced oxidative stress, they were anti-apoptotic. Cumulatively, the obtained results show the complexity of dap-MWCNT/PMØ interactions and suggest that this complex could be investigated for the treatment of dapsone-sensitive intracellular microorganisms or inflammatory diseases responding to dapsone therapy.",
publisher = "Belgrade : University of Belgrade, Faculty of Technology and Metallurgy",
title = "Sinteza, karakterizacija i primena funkcionalizovanih ugljeničnih nanocevi",
url = "https://hdl.handle.net/21.15107/rcub_dais_82"
}
Vuković, G.. (2010). Sinteza, karakterizacija i primena funkcionalizovanih ugljeničnih nanocevi. 
Belgrade : University of Belgrade, Faculty of Technology and Metallurgy..
https://hdl.handle.net/21.15107/rcub_dais_82
Vuković G. Sinteza, karakterizacija i primena funkcionalizovanih ugljeničnih nanocevi. 2010;.
https://hdl.handle.net/21.15107/rcub_dais_82 .
Vuković, Goran, "Sinteza, karakterizacija i primena funkcionalizovanih ugljeničnih nanocevi" (2010),
https://hdl.handle.net/21.15107/rcub_dais_82 .

Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite

Vukomanović, Marija; Mitrić, Miodrag; Škapin, Srečo Davor; Žagar, Ema; Plavec, Janez; Ignjatović, Nenad; Uskoković, Dragan

(2010)

TY  - JOUR
AU  - Vukomanović, Marija
AU  - Mitrić, Miodrag
AU  - Škapin, Srečo Davor
AU  - Žagar, Ema
AU  - Plavec, Janez
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/2747
AB  - In this work poly(D,L-lactide-co-glycolide) (PLGA) and a poly(D,L-lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) composite processed in an ultrasonic field at higher (25 degrees C) and lower (8 degrees C) temperatures were studied with respect to the molecular properties of the obtained materials. The processing of the PLGA and the PLGA/HAp composite in an ultrasonic field resulted in a change of molar mass averages of the polymer/polymeric part of these materials, while an amorphous structure and a 50:50 lactide-to-glycolide co-monomer ratio were preserved without the formation of crystalline oligomers. However, mobility of polymeric chains obtained after ultrasonic processing was lower indicating ordering the structure of polymeric chains as a result of processing. Additionally, it was observed that the mobility of the PLGA macromolecules was lower within the composite in comparison with the mobility of the chains within the PLGA alone in the case when both were obtained after ultrasonic processing. This was a consequence of the structure formation through the interactions between the PLGA and the HAp. Based on these results different degradation rate of PLGA in composite can be expected, which is important in the application of this material for the controlled drug delivery of medicaments. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Ultrasonics Sonochemistry
T1  - Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite
SP  - 902
EP  - 908
VL  - 17
IS  - 5
DO  - 10.1016/j.ultsonch.2010.01.007
UR  - https://hdl.handle.net/21.15107/rcub_dais_2747
ER  - 
@article{
author = "Vukomanović, Marija and Mitrić, Miodrag and Škapin, Srečo Davor and Žagar, Ema and Plavec, Janez and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
abstract = "In this work poly(D,L-lactide-co-glycolide) (PLGA) and a poly(D,L-lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) composite processed in an ultrasonic field at higher (25 degrees C) and lower (8 degrees C) temperatures were studied with respect to the molecular properties of the obtained materials. The processing of the PLGA and the PLGA/HAp composite in an ultrasonic field resulted in a change of molar mass averages of the polymer/polymeric part of these materials, while an amorphous structure and a 50:50 lactide-to-glycolide co-monomer ratio were preserved without the formation of crystalline oligomers. However, mobility of polymeric chains obtained after ultrasonic processing was lower indicating ordering the structure of polymeric chains as a result of processing. Additionally, it was observed that the mobility of the PLGA macromolecules was lower within the composite in comparison with the mobility of the chains within the PLGA alone in the case when both were obtained after ultrasonic processing. This was a consequence of the structure formation through the interactions between the PLGA and the HAp. Based on these results different degradation rate of PLGA in composite can be expected, which is important in the application of this material for the controlled drug delivery of medicaments. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Ultrasonics Sonochemistry",
title = "Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite",
pages = "902-908",
volume = "17",
number = "5",
doi = "10.1016/j.ultsonch.2010.01.007",
url = "https://hdl.handle.net/21.15107/rcub_dais_2747"
}
Vukomanović, M., Mitrić, M., Škapin, S. D., Žagar, E., Plavec, J., Ignjatović, N.,& Uskoković, D.. (2010). Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite. in Ultrasonics Sonochemistry, 17(5), 902-908.
https://doi.org/10.1016/j.ultsonch.2010.01.007
https://hdl.handle.net/21.15107/rcub_dais_2747
Vukomanović M, Mitrić M, Škapin SD, Žagar E, Plavec J, Ignjatović N, Uskoković D. Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite. in Ultrasonics Sonochemistry. 2010;17(5):902-908.
doi:10.1016/j.ultsonch.2010.01.007
https://hdl.handle.net/21.15107/rcub_dais_2747 .
Vukomanović, Marija, Mitrić, Miodrag, Škapin, Srečo Davor, Žagar, Ema, Plavec, Janez, Ignjatović, Nenad, Uskoković, Dragan, "Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite" in Ultrasonics Sonochemistry, 17, no. 5 (2010):902-908,
https://doi.org/10.1016/j.ultsonch.2010.01.007 .,
https://hdl.handle.net/21.15107/rcub_dais_2747 .
7
6
7

Hydrothermal synthesis of LiFePO4 in presence of different organic additives

Jović, Maja; Stojanović, Zoran S.; Jugović, Dragana; Škapin, Srečo Davor; Uskoković, Dragan

(Belgrade : Society of Physical Chemists of Serbia, 2010)

TY  - CONF
AU  - Jović, Maja
AU  - Stojanović, Zoran S.
AU  - Jugović, Dragana
AU  - Škapin, Srečo Davor
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3496
AB  - In this work we have investigated possibility to obtain pure LiFePO4 powder using different organic additives during hydrothermal synthesis at 180°C. Phase pure phospho olivine was obtained in presence of polyvinylpyrrolidone, while addition of polyvinyl alcohol leads to formation of LiFePO4 with impurities. Impurity phase was successfully avoided by introducing citric acid into reaction vessel. Phase composition was determined by XRPD. Morphology was revealed by particle size analyzer and FESEM.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - Physical Chemistry 2010 : proceedings. Vol. 2 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade
T1  - Hydrothermal synthesis of LiFePO4 in presence of different organic additives
SP  - 441
EP  - 443
UR  - https://hdl.handle.net/21.15107/rcub_dais_3496
ER  - 
@conference{
author = "Jović, Maja and Stojanović, Zoran S. and Jugović, Dragana and Škapin, Srečo Davor and Uskoković, Dragan",
year = "2010",
abstract = "In this work we have investigated possibility to obtain pure LiFePO4 powder using different organic additives during hydrothermal synthesis at 180°C. Phase pure phospho olivine was obtained in presence of polyvinylpyrrolidone, while addition of polyvinyl alcohol leads to formation of LiFePO4 with impurities. Impurity phase was successfully avoided by introducing citric acid into reaction vessel. Phase composition was determined by XRPD. Morphology was revealed by particle size analyzer and FESEM.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "Physical Chemistry 2010 : proceedings. Vol. 2 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade",
title = "Hydrothermal synthesis of LiFePO4 in presence of different organic additives",
pages = "441-443",
url = "https://hdl.handle.net/21.15107/rcub_dais_3496"
}
Jović, M., Stojanović, Z. S., Jugović, D., Škapin, S. D.,& Uskoković, D.. (2010). Hydrothermal synthesis of LiFePO4 in presence of different organic additives. in Physical Chemistry 2010 : proceedings. Vol. 2 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade
Belgrade : Society of Physical Chemists of Serbia., 441-443.
https://hdl.handle.net/21.15107/rcub_dais_3496
Jović M, Stojanović ZS, Jugović D, Škapin SD, Uskoković D. Hydrothermal synthesis of LiFePO4 in presence of different organic additives. in Physical Chemistry 2010 : proceedings. Vol. 2 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade. 2010;:441-443.
https://hdl.handle.net/21.15107/rcub_dais_3496 .
Jović, Maja, Stojanović, Zoran S., Jugović, Dragana, Škapin, Srečo Davor, Uskoković, Dragan, "Hydrothermal synthesis of LiFePO4 in presence of different organic additives" in Physical Chemistry 2010 : proceedings. Vol. 2 / 10th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 21-24 September 2010, Belgrade (2010):441-443,
https://hdl.handle.net/21.15107/rcub_dais_3496 .

Green synthesis of PGA-capped silver nanoparticles and their characterization

Savanović, Igor; Stevanović, Magdalena; Škapin, Srečo Davor; Marković, M.; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Savanović, Igor
AU  - Stevanović, Magdalena
AU  - Škapin, Srečo Davor
AU  - Marković, M.
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3450
AB  - Owing to their persistent antibacterial properties, Ag nanoparticles are increasingly used in clinical practice and investigated in recent laboratory research. Although there are a number of methods for the synthesis of Ag nanoparticles, recent research trends comply with the requirements of Non-toxic Environmental Chemistry. In this study, the synthesis of silver nanoparticles was based on the principles of green chemistry. In order to improve their antibacterial properties and biocompatibility, Ag nanoparticles can be coated with various biocompatible and biodegradable polymers that can ensure their better interaction with cells and more favourable size distribution. Poly(α, γ-glutamic acid) is one of the polymers that have the required properties; it also serves as particle stabilizer. The synthesis of Ag nanoparticles was performed by a modified chemical reduction method with glucose as the reducing agent. The samples were characterized by UV/ Vis spectroscopy, FESEM and Zeta potential measurements
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Green synthesis of PGA-capped silver nanoparticles and their characterization
SP  - 11
EP  - 11
UR  - https://hdl.handle.net/21.15107/rcub_dais_3450
ER  - 
@conference{
author = "Savanović, Igor and Stevanović, Magdalena and Škapin, Srečo Davor and Marković, M. and Uskoković, Dragan",
year = "2010",
abstract = "Owing to their persistent antibacterial properties, Ag nanoparticles are increasingly used in clinical practice and investigated in recent laboratory research. Although there are a number of methods for the synthesis of Ag nanoparticles, recent research trends comply with the requirements of Non-toxic Environmental Chemistry. In this study, the synthesis of silver nanoparticles was based on the principles of green chemistry. In order to improve their antibacterial properties and biocompatibility, Ag nanoparticles can be coated with various biocompatible and biodegradable polymers that can ensure their better interaction with cells and more favourable size distribution. Poly(α, γ-glutamic acid) is one of the polymers that have the required properties; it also serves as particle stabilizer. The synthesis of Ag nanoparticles was performed by a modified chemical reduction method with glucose as the reducing agent. The samples were characterized by UV/ Vis spectroscopy, FESEM and Zeta potential measurements",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Green synthesis of PGA-capped silver nanoparticles and their characterization",
pages = "11-11",
url = "https://hdl.handle.net/21.15107/rcub_dais_3450"
}
Savanović, I., Stevanović, M., Škapin, S. D., Marković, M.,& Uskoković, D.. (2010). Green synthesis of PGA-capped silver nanoparticles and their characterization. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 11-11.
https://hdl.handle.net/21.15107/rcub_dais_3450
Savanović I, Stevanović M, Škapin SD, Marković M, Uskoković D. Green synthesis of PGA-capped silver nanoparticles and their characterization. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:11-11.
https://hdl.handle.net/21.15107/rcub_dais_3450 .
Savanović, Igor, Stevanović, Magdalena, Škapin, Srečo Davor, Marković, M., Uskoković, Dragan, "Green synthesis of PGA-capped silver nanoparticles and their characterization" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):11-11,
https://hdl.handle.net/21.15107/rcub_dais_3450 .

Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry

Vuković, Gorica; Lazić, Sanja; Šunjka, Dragana; Bursić, Vojislava; Šarčev, Ivan; Vukomanović, Marija; Ignjatović, Nenad; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Vuković, Gorica
AU  - Lazić, Sanja
AU  - Šunjka, Dragana
AU  - Bursić, Vojislava
AU  - Šarčev, Ivan
AU  - Vukomanović, Marija
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3453
AB  - Clindamycin was determined in pig plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS). The multiple reaction monitoring (MRM) mode of precursor-product ion transitions for clindamycin (m/z=421.1/126.1) and the internal standard, caffeine (m/z=192/125) was used. The samples were prepared by two methods: 0.1% formic acid in methanol and 1.5% trichloacetic acid. The recovery for the two preparation methods at 0.05mg/ml (n=6) was found to be for the first 104.3% and for the second method 106.5%, with repeatability RSD 1.1% and RSD 4.34%, respectively. The results of the comparison of the two different preparation methods of samples demonstrated that both methods were satisfactory.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry
SP  - 19
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_dais_3453
ER  - 
@conference{
author = "Vuković, Gorica and Lazić, Sanja and Šunjka, Dragana and Bursić, Vojislava and Šarčev, Ivan and Vukomanović, Marija and Ignjatović, Nenad and Uskoković, Dragan",
year = "2010",
abstract = "Clindamycin was determined in pig plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS). The multiple reaction monitoring (MRM) mode of precursor-product ion transitions for clindamycin (m/z=421.1/126.1) and the internal standard, caffeine (m/z=192/125) was used. The samples were prepared by two methods: 0.1% formic acid in methanol and 1.5% trichloacetic acid. The recovery for the two preparation methods at 0.05mg/ml (n=6) was found to be for the first 104.3% and for the second method 106.5%, with repeatability RSD 1.1% and RSD 4.34%, respectively. The results of the comparison of the two different preparation methods of samples demonstrated that both methods were satisfactory.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry",
pages = "19-19",
url = "https://hdl.handle.net/21.15107/rcub_dais_3453"
}
Vuković, G., Lazić, S., Šunjka, D., Bursić, V., Šarčev, I., Vukomanović, M., Ignjatović, N.,& Uskoković, D.. (2010). Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 19-19.
https://hdl.handle.net/21.15107/rcub_dais_3453
Vuković G, Lazić S, Šunjka D, Bursić V, Šarčev I, Vukomanović M, Ignjatović N, Uskoković D. Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:19-19.
https://hdl.handle.net/21.15107/rcub_dais_3453 .
Vuković, Gorica, Lazić, Sanja, Šunjka, Dragana, Bursić, Vojislava, Šarčev, Ivan, Vukomanović, Marija, Ignjatović, Nenad, Uskoković, Dragan, "Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):19-19,
https://hdl.handle.net/21.15107/rcub_dais_3453 .

Influence of heating rate on two-step sintering behaviour of different hydroxyapatite nanopowders

Lukić, Miodrag J.; Stojanović, Zoran S.; Veselinović, Ljiljana; Marković, Smilja; Uskoković, Dragan

(2010)

TY  - CONF
AU  - Lukić, Miodrag J.
AU  - Stojanović, Zoran S.
AU  - Veselinović, Ljiljana
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3559
AB  - Producing of dense nanostructured calcium phosphate-based bioceramics represents a challenging issue in biomaterial science. High volume fraction of energetically rich grain boundaries contributes to improved attachment of chemical species, which are important in the processes of bone tissue regeneration. Beside that, nanostructured ceramics exhibited better mechanical properties due to changed fracture path. The process of presureless sintering is the most compatible route for industrial fabrication of dense bioceramic materials, but it is often connected with accelerated grain growth in final sintering stage. In the method of two-step sintering (TSS) the difference between kinetics of grain boundary diffusion and grain boundary migration is used to obtain almost full dense, nanostructured ceramics. However, designing of proper sintering parameters is very important in every sintering technique employed. In this study, hydroxyapatite nanopowders were synthesized by different methods, precisely, chemical precipitation and hydrothermal processing of precipitate. The prepared powders were pressed in pellets and heated with different heating rates (2, 5, 10 ºC/min), with short isothermal dwell at certain temperature range. From that shrinkage curves the appropriate conditions were selected to design TSS experiments. The impact of heating rate on final density, phase composition, average grain size and microstructural uniformity is discussed. Furthermore, mechanical properties were determined.
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Influence of heating rate on two-step sintering behaviour of different hydroxyapatite nanopowders
SP  - 142
EP  - 142
UR  - https://hdl.handle.net/21.15107/rcub_dais_3559
ER  - 
@conference{
author = "Lukić, Miodrag J. and Stojanović, Zoran S. and Veselinović, Ljiljana and Marković, Smilja and Uskoković, Dragan",
year = "2010",
abstract = "Producing of dense nanostructured calcium phosphate-based bioceramics represents a challenging issue in biomaterial science. High volume fraction of energetically rich grain boundaries contributes to improved attachment of chemical species, which are important in the processes of bone tissue regeneration. Beside that, nanostructured ceramics exhibited better mechanical properties due to changed fracture path. The process of presureless sintering is the most compatible route for industrial fabrication of dense bioceramic materials, but it is often connected with accelerated grain growth in final sintering stage. In the method of two-step sintering (TSS) the difference between kinetics of grain boundary diffusion and grain boundary migration is used to obtain almost full dense, nanostructured ceramics. However, designing of proper sintering parameters is very important in every sintering technique employed. In this study, hydroxyapatite nanopowders were synthesized by different methods, precisely, chemical precipitation and hydrothermal processing of precipitate. The prepared powders were pressed in pellets and heated with different heating rates (2, 5, 10 ºC/min), with short isothermal dwell at certain temperature range. From that shrinkage curves the appropriate conditions were selected to design TSS experiments. The impact of heating rate on final density, phase composition, average grain size and microstructural uniformity is discussed. Furthermore, mechanical properties were determined.",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Influence of heating rate on two-step sintering behaviour of different hydroxyapatite nanopowders",
pages = "142-142",
url = "https://hdl.handle.net/21.15107/rcub_dais_3559"
}
Lukić, M. J., Stojanović, Z. S., Veselinović, L., Marković, S.,& Uskoković, D.. (2010). Influence of heating rate on two-step sintering behaviour of different hydroxyapatite nanopowders. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010, 142-142.
https://hdl.handle.net/21.15107/rcub_dais_3559
Lukić MJ, Stojanović ZS, Veselinović L, Marković S, Uskoković D. Influence of heating rate on two-step sintering behaviour of different hydroxyapatite nanopowders. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:142-142.
https://hdl.handle.net/21.15107/rcub_dais_3559 .
Lukić, Miodrag J., Stojanović, Zoran S., Veselinović, Ljiljana, Marković, Smilja, Uskoković, Dragan, "Influence of heating rate on two-step sintering behaviour of different hydroxyapatite nanopowders" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):142-142,
https://hdl.handle.net/21.15107/rcub_dais_3559 .

Structural characterization of synthetic and biological carbonated hydroxyapatite

Veselinović, Ljiljana; Lukić, Miodrag J.; Karanović, Ljiljana; Ignjatović, Nenad; Marković, Smilja; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Veselinović, Ljiljana
AU  - Lukić, Miodrag J.
AU  - Karanović, Ljiljana
AU  - Ignjatović, Nenad
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3451
AB  - It is well known that inorganic part of bones and teeth are impure form of hydroxyapatite, (HAp) Ca10(PO4)6(OH) 2. During the past few decades, great efforts have been invested to develop synthetic equivalent of natural apatite. The major difference of natural bioapatites from hydroxyapatites is in the presence of certain content of 2- CO3 ions in the structure. The presence of the 2- CO3 ions in the HAp structure influences the reactivity and stability. Therefore, the exact content of 2- CO3 ions as well as their arrangement in the structure is very important. The aim of our work is comparative analysis of the biological carbonated hydroxyapatite extracted from human alveolar bone and synthesized carbonated hydroxyapatite (BCHAp). Structural and microstructural parameters were determined through Rietveld refinement of recorded XRPD data, and with transmission electron microscopy (TEM). Microstructure analysis showed anisotropic X-ray line broadening due to the small crystallite size (about 10 nm) as well as anisotropic growth of crystallites. The Raman spectroscopy confirmed the apatite structure and crystallinity.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Structural characterization of synthetic and biological carbonated hydroxyapatite
SP  - 12
EP  - 12
UR  - https://hdl.handle.net/21.15107/rcub_dais_3451
ER  - 
@conference{
author = "Veselinović, Ljiljana and Lukić, Miodrag J. and Karanović, Ljiljana and Ignjatović, Nenad and Marković, Smilja and Uskoković, Dragan",
year = "2010",
abstract = "It is well known that inorganic part of bones and teeth are impure form of hydroxyapatite, (HAp) Ca10(PO4)6(OH) 2. During the past few decades, great efforts have been invested to develop synthetic equivalent of natural apatite. The major difference of natural bioapatites from hydroxyapatites is in the presence of certain content of 2- CO3 ions in the structure. The presence of the 2- CO3 ions in the HAp structure influences the reactivity and stability. Therefore, the exact content of 2- CO3 ions as well as their arrangement in the structure is very important. The aim of our work is comparative analysis of the biological carbonated hydroxyapatite extracted from human alveolar bone and synthesized carbonated hydroxyapatite (BCHAp). Structural and microstructural parameters were determined through Rietveld refinement of recorded XRPD data, and with transmission electron microscopy (TEM). Microstructure analysis showed anisotropic X-ray line broadening due to the small crystallite size (about 10 nm) as well as anisotropic growth of crystallites. The Raman spectroscopy confirmed the apatite structure and crystallinity.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Structural characterization of synthetic and biological carbonated hydroxyapatite",
pages = "12-12",
url = "https://hdl.handle.net/21.15107/rcub_dais_3451"
}
Veselinović, L., Lukić, M. J., Karanović, L., Ignjatović, N., Marković, S.,& Uskoković, D.. (2010). Structural characterization of synthetic and biological carbonated hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 12-12.
https://hdl.handle.net/21.15107/rcub_dais_3451
Veselinović L, Lukić MJ, Karanović L, Ignjatović N, Marković S, Uskoković D. Structural characterization of synthetic and biological carbonated hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:12-12.
https://hdl.handle.net/21.15107/rcub_dais_3451 .
Veselinović, Ljiljana, Lukić, Miodrag J., Karanović, Ljiljana, Ignjatović, Nenad, Marković, Smilja, Uskoković, Dragan, "Structural characterization of synthetic and biological carbonated hydroxyapatite" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):12-12,
https://hdl.handle.net/21.15107/rcub_dais_3451 .

The influence of powder characteristics on two-step sintering behavior of hydroxyapatite

Lukić, Miodrag J.; Stojanović, Zoran S.; Veselinović, Ljiljana; Škapin, Srečo Davor; Bračko, Ines; Marković, Smilja; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2010)

TY  - CONF
AU  - Lukić, Miodrag J.
AU  - Stojanović, Zoran S.
AU  - Veselinović, Ljiljana
AU  - Škapin, Srečo Davor
AU  - Bračko, Ines
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/3449
AB  - Fabrication of full dense ceramic materials on the basis of hydroxyapatite (HAp) and biphasic calcium phosphate (BCP) with controllable microstructural and compositional characteristics attracts considerable efforts. Various synthesis and sintering methods were applied in order to achieve desirable material properties. In this study different nanopowders were produced and processed via two-step sintering (TSS) approach. Characterization of synthesized nanopowders were done by XRD, BET, FE-SEM, TEM and thermal analysis methods, while microstructural and chemical characterizations of sintered samples were performed through FE-SEM and XRD analysis. A possibility for obtaining full dense ceramics with suppressed grain growth is discussed on the basis of inherent nanopowders characteristics. Certain attention would be paid on thermal behavior of Ca-deficient HAp systems.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - The influence of powder characteristics on two-step sintering behavior of hydroxyapatite
SP  - 11
EP  - 11
UR  - https://hdl.handle.net/21.15107/rcub_dais_3449
ER  - 
@conference{
author = "Lukić, Miodrag J. and Stojanović, Zoran S. and Veselinović, Ljiljana and Škapin, Srečo Davor and Bračko, Ines and Marković, Smilja and Uskoković, Dragan",
year = "2010",
abstract = "Fabrication of full dense ceramic materials on the basis of hydroxyapatite (HAp) and biphasic calcium phosphate (BCP) with controllable microstructural and compositional characteristics attracts considerable efforts. Various synthesis and sintering methods were applied in order to achieve desirable material properties. In this study different nanopowders were produced and processed via two-step sintering (TSS) approach. Characterization of synthesized nanopowders were done by XRD, BET, FE-SEM, TEM and thermal analysis methods, while microstructural and chemical characterizations of sintered samples were performed through FE-SEM and XRD analysis. A possibility for obtaining full dense ceramics with suppressed grain growth is discussed on the basis of inherent nanopowders characteristics. Certain attention would be paid on thermal behavior of Ca-deficient HAp systems.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "The influence of powder characteristics on two-step sintering behavior of hydroxyapatite",
pages = "11-11",
url = "https://hdl.handle.net/21.15107/rcub_dais_3449"
}
Lukić, M. J., Stojanović, Z. S., Veselinović, L., Škapin, S. D., Bračko, I., Marković, S.,& Uskoković, D.. (2010). The influence of powder characteristics on two-step sintering behavior of hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 11-11.
https://hdl.handle.net/21.15107/rcub_dais_3449
Lukić MJ, Stojanović ZS, Veselinović L, Škapin SD, Bračko I, Marković S, Uskoković D. The influence of powder characteristics on two-step sintering behavior of hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:11-11.
https://hdl.handle.net/21.15107/rcub_dais_3449 .
Lukić, Miodrag J., Stojanović, Zoran S., Veselinović, Ljiljana, Škapin, Srečo Davor, Bračko, Ines, Marković, Smilja, Uskoković, Dragan, "The influence of powder characteristics on two-step sintering behavior of hydroxyapatite" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):11-11,
https://hdl.handle.net/21.15107/rcub_dais_3449 .