Ignjatović, Nenad

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Authority KeyName Variants
orcid::0000-0002-5749-094X
  • Ignjatović, Nenad (180)
Projects
Molecular designing of nanoparticles with controlled morphological and physicochemical characteristics and functional materials based on them Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou
Virtual human osteoarticular system and its application in preclinical and clinical practice United States National Institutes of Health (NIH) / National Institute of Dental and Craniofacial Research (NIDCR), Grant K99-DE021416
Biokompatibilnost i mogućnosti primene biomaterijala na bazi hidroksiapatita i biopolimera u tkivnoj reparaciji - eksperimentalna i klinička studija New approach in designing materials for energy conversion and energy storage systems
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200175 (Institute of Technical Sciences of SASA, Belgrade) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM)
Regeneracija skeletnih tkiva pomognuta biomaterijalima kao tkivnim matricama - in vivo i in vitro studija Electrochemical synthesis and characterization of nanostructured functional materials for application in new technologies
Ministry of Health (Bando Ricerca Finalizzata 2016, no. GR-2016-02364704) Synthesis, characterization and biological investigation of steroid derivatives and their molecular aggregates
Rational design and synthesis of biologically active and coordination compounds and functional materials, relevant for (bio)nanotechnology Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200378 (Institute of Information Technology)
Advanced technologies for monitoring and environmental protection from chemical pollutants and radiation burden Modifikacija, sinteza i analiza nanostrukturnih materijala jonskim snopovima, gama zračenjem i vakuumskim deponovanjem
Bilateral cooperation program between the Republic of Serbia and the Republic of Slovenia http://dx.doi.org/10.13039/501100004564
The study of physicochemical and biochemical processes in living environment that have impacts on pollution and the investigation of possibilities for minimizing the consequences Synthesis and characterization of novel functional polymers and polymeric nanocomposites
Pain Control and Molecular Mechanisms as Factors for Tissue Regeneration in Dentistry in Healthy and Diabetic Patients Preventive, therapeutic, and ethical approach in preclinical and clinical studies of the genes and modulators of redox cell signaling in immune, inflammatory and proliferative cell response
Functional, Functionalized and Advanced Nanomaterials Development of micro- and nanosystems as carriers for drugs with anti-inflammatory effect and methods for their characterization
Ministry of Science and Environmental Protection of the Republic of Serbia Ministry of Science, Technology and Development of the Republic of Serbia. Grant Number: 1431
Research Committee of The Hong Kong Polytechnic University (Project code: A-PF81) Serbia, Project grant No. 11-14629-4/16, Faculty of Medicine, University of Niš

Author's Bibliography

Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition

Pantović-Pavlović, Marijana; Pavlović, Miroslav; Kovačina, Jovanka; Stanojević, Boris; Stevanović, Jasmina; Panić, Vladimir; Ignjatović, Nenad

(Belgrade : Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Pantović-Pavlović, Marijana
AU  - Pavlović, Miroslav
AU  - Kovačina, Jovanka
AU  - Stanojević, Boris
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11738
AB  - The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 and ACP/TiO2/ /ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells exposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. These findings show that there was improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for applications in medicine and stomatology.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition
SP  - 555
EP  - 559
VL  - 86
IS  - 6
DO  - 10.2298/JSC210211024P
UR  - https://hdl.handle.net/21.15107/rcub_dais_11738
ER  - 
@article{
author = "Pantović-Pavlović, Marijana and Pavlović, Miroslav and Kovačina, Jovanka and Stanojević, Boris and Stevanović, Jasmina and Panić, Vladimir and Ignjatović, Nenad",
year = "2021",
abstract = "The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 and ACP/TiO2/ /ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells exposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. These findings show that there was improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for applications in medicine and stomatology.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition",
pages = "555-559",
volume = "86",
number = "6",
doi = "10.2298/JSC210211024P",
url = "https://hdl.handle.net/21.15107/rcub_dais_11738"
}
Pantović-Pavlović, M., Pavlović, M., Kovačina, J., Stanojević, B., Stevanović, J., Panić, V.,& Ignjatović, N.. (2021). Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(6), 555-559.
https://doi.org/10.2298/JSC210211024P
https://hdl.handle.net/21.15107/rcub_dais_11738
Pantović-Pavlović M, Pavlović M, Kovačina J, Stanojević B, Stevanović J, Panić V, Ignjatović N. Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition. in Journal of the Serbian Chemical Society. 2021;86(6):555-559.
doi:10.2298/JSC210211024P
https://hdl.handle.net/21.15107/rcub_dais_11738 .
Pantović-Pavlović, Marijana, Pavlović, Miroslav, Kovačina, Jovanka, Stanojević, Boris, Stevanović, Jasmina, Panić, Vladimir, Ignjatović, Nenad, "Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition" in Journal of the Serbian Chemical Society, 86, no. 6 (2021):555-559,
https://doi.org/10.2298/JSC210211024P .,
https://hdl.handle.net/21.15107/rcub_dais_11738 .
1
1
1

Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties

Pantović Pavlović, Marijana R.; Stanojević, Boris P.; Pavlović, Miroslav M.; Mihailović, Marija D.; Stevanović, Jasmina; Panić, Vladimir V.; Ignjatović, Nenad

(American Chemical Society (ACS), 2021)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Stanojević, Boris P.
AU  - Pavlović, Miroslav M.
AU  - Mihailović, Marija D.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11784
AB  - The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.
PB  - American Chemical Society (ACS)
T2  - ACS Biomaterials Science & Engineering
T1  - Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties
SP  - 3088
EP  - 3102
VL  - 7
IS  - 7
DO  - 10.1021/acsbiomaterials.1c00035
UR  - https://hdl.handle.net/21.15107/rcub_dais_11784
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Stanojević, Boris P. and Pavlović, Miroslav M. and Mihailović, Marija D. and Stevanović, Jasmina and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.",
publisher = "American Chemical Society (ACS)",
journal = "ACS Biomaterials Science & Engineering",
title = "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties",
pages = "3088-3102",
volume = "7",
number = "7",
doi = "10.1021/acsbiomaterials.1c00035",
url = "https://hdl.handle.net/21.15107/rcub_dais_11784"
}
Pantović Pavlović, M. R., Stanojević, B. P., Pavlović, M. M., Mihailović, M. D., Stevanović, J., Panić, V. V.,& Ignjatović, N.. (2021). Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering
American Chemical Society (ACS)., 7(7), 3088-3102.
https://doi.org/10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11784
Pantović Pavlović MR, Stanojević BP, Pavlović MM, Mihailović MD, Stevanović J, Panić VV, Ignjatović N. Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering. 2021;7(7):3088-3102.
doi:10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11784 .
Pantović Pavlović, Marijana R., Stanojević, Boris P., Pavlović, Miroslav M., Mihailović, Marija D., Stevanović, Jasmina, Panić, Vladimir V., Ignjatović, Nenad, "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties" in ACS Biomaterials Science & Engineering, 7, no. 7 (2021):3088-3102,
https://doi.org/10.1021/acsbiomaterials.1c00035 .,
https://hdl.handle.net/21.15107/rcub_dais_11784 .
2

Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties

Pantović Pavlović, Marijana R.; Stanojević, Boris P.; Pavlović, Miroslav M.; Mihailović, Marija D.; Stevanović, Jasmina; Panić, Vladimir V.; Ignjatović, Nenad

(American Chemical Society (ACS), 2021)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Stanojević, Boris P.
AU  - Pavlović, Miroslav M.
AU  - Mihailović, Marija D.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11739
AB  - The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.
PB  - American Chemical Society (ACS)
T2  - ACS Biomaterials Science & Engineering
T1  - Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties
SP  - 3088
EP  - 3102
VL  - 7
IS  - 7
DO  - 10.1021/acsbiomaterials.1c00035
UR  - https://hdl.handle.net/21.15107/rcub_dais_11739
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Stanojević, Boris P. and Pavlović, Miroslav M. and Mihailović, Marija D. and Stevanović, Jasmina and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.",
publisher = "American Chemical Society (ACS)",
journal = "ACS Biomaterials Science & Engineering",
title = "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties",
pages = "3088-3102",
volume = "7",
number = "7",
doi = "10.1021/acsbiomaterials.1c00035",
url = "https://hdl.handle.net/21.15107/rcub_dais_11739"
}
Pantović Pavlović, M. R., Stanojević, B. P., Pavlović, M. M., Mihailović, M. D., Stevanović, J., Panić, V. V.,& Ignjatović, N.. (2021). Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering
American Chemical Society (ACS)., 7(7), 3088-3102.
https://doi.org/10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11739
Pantović Pavlović MR, Stanojević BP, Pavlović MM, Mihailović MD, Stevanović J, Panić VV, Ignjatović N. Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering. 2021;7(7):3088-3102.
doi:10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11739 .
Pantović Pavlović, Marijana R., Stanojević, Boris P., Pavlović, Miroslav M., Mihailović, Marija D., Stevanović, Jasmina, Panić, Vladimir V., Ignjatović, Nenad, "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties" in ACS Biomaterials Science & Engineering, 7, no. 7 (2021):3088-3102,
https://doi.org/10.1021/acsbiomaterials.1c00035 .,
https://hdl.handle.net/21.15107/rcub_dais_11739 .
2

Interdisciplinary crossover for rapid advancements - collaboration between medical and engineering scientists with the focus on Serbia

Ignjatović, Nenad; Mitković, Milorad; Obradović, Bojana; Stamenković, Dragoslav; Dankuc, Dragan; Manić, Miodrag; Grbović, Aleksandar; Kovačević, Branko; Đukanović, Ljubica

(Serbian Medical Society, 2021)

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Mitković, Milorad
AU  - Obradović, Bojana
AU  - Stamenković, Dragoslav
AU  - Dankuc, Dragan
AU  - Manić, Miodrag
AU  - Grbović, Aleksandar
AU  - Kovačević, Branko
AU  - Đukanović, Ljubica
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11643
AB  - Over the past decades, development of engineering sciences has vastly contributed to advancements in medicine by production of numerous devices for diagnostics and treatment. In the middle of the 20th century, a new scientific field, biomedical engineering (BE), was established, which has developed into an extremely complex scientific discipline requiring a distinctive educational profile. Various study programs in BE have been established at universities around the world but also at several universities in Serbia. Also, intensive research in this field is performed at several scientific institutions in Serbia. In the present paper, short summaries of the research results of several groups of engineers and medical doctors are presented as an illustration of the wide field of BE research and possibilities of its application in diagnosis and therapy of various diseases.
PB  - Serbian Medical Society
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Interdisciplinary crossover for rapid advancements - collaboration between medical and engineering scientists with the focus on Serbia
SP  - 229
EP  - 235
VL  - 149
IS  - 3-4
DO  - 10.2298/SARH210110021D
UR  - https://hdl.handle.net/21.15107/rcub_dais_11643
ER  - 
@article{
author = "Ignjatović, Nenad and Mitković, Milorad and Obradović, Bojana and Stamenković, Dragoslav and Dankuc, Dragan and Manić, Miodrag and Grbović, Aleksandar and Kovačević, Branko and Đukanović, Ljubica",
year = "2021",
abstract = "Over the past decades, development of engineering sciences has vastly contributed to advancements in medicine by production of numerous devices for diagnostics and treatment. In the middle of the 20th century, a new scientific field, biomedical engineering (BE), was established, which has developed into an extremely complex scientific discipline requiring a distinctive educational profile. Various study programs in BE have been established at universities around the world but also at several universities in Serbia. Also, intensive research in this field is performed at several scientific institutions in Serbia. In the present paper, short summaries of the research results of several groups of engineers and medical doctors are presented as an illustration of the wide field of BE research and possibilities of its application in diagnosis and therapy of various diseases.",
publisher = "Serbian Medical Society",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Interdisciplinary crossover for rapid advancements - collaboration between medical and engineering scientists with the focus on Serbia",
pages = "229-235",
volume = "149",
number = "3-4",
doi = "10.2298/SARH210110021D",
url = "https://hdl.handle.net/21.15107/rcub_dais_11643"
}
Ignjatović, N., Mitković, M., Obradović, B., Stamenković, D., Dankuc, D., Manić, M., Grbović, A., Kovačević, B.,& Đukanović, L.. (2021). Interdisciplinary crossover for rapid advancements - collaboration between medical and engineering scientists with the focus on Serbia. in Srpski arhiv za celokupno lekarstvo
Serbian Medical Society., 149(3-4), 229-235.
https://doi.org/10.2298/SARH210110021D
https://hdl.handle.net/21.15107/rcub_dais_11643
Ignjatović N, Mitković M, Obradović B, Stamenković D, Dankuc D, Manić M, Grbović A, Kovačević B, Đukanović L. Interdisciplinary crossover for rapid advancements - collaboration between medical and engineering scientists with the focus on Serbia. in Srpski arhiv za celokupno lekarstvo. 2021;149(3-4):229-235.
doi:10.2298/SARH210110021D
https://hdl.handle.net/21.15107/rcub_dais_11643 .
Ignjatović, Nenad, Mitković, Milorad, Obradović, Bojana, Stamenković, Dragoslav, Dankuc, Dragan, Manić, Miodrag, Grbović, Aleksandar, Kovačević, Branko, Đukanović, Ljubica, "Interdisciplinary crossover for rapid advancements - collaboration between medical and engineering scientists with the focus on Serbia" in Srpski arhiv za celokupno lekarstvo, 149, no. 3-4 (2021):229-235,
https://doi.org/10.2298/SARH210110021D .,
https://hdl.handle.net/21.15107/rcub_dais_11643 .
2

Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035

Pantović-Pavlović, Marijana; Stanojević, Boris; Pavlović, Miroslav M.; Mihailović, Marija D.; Stevanović, Jasmina; Panić, Vladimir V.; Ignjatović, Nenad

(American Chemical Society (ACS), 2021)

TY  - DATA
AU  - Pantović-Pavlović, Marijana
AU  - Stanojević, Boris
AU  - Pavlović, Miroslav M.
AU  - Mihailović, Marija D.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11740
AB  - The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. Supplementary information: The ANOVA results of antimicrobial activity on S. aureus are shown in Table S1 and the ANOVA results of antimicrobial activity on P. aeruginosa are shown in Table S2. The analysis showed significant difference at the 5% level of confidence.
PB  - American Chemical Society (ACS)
T2  - ACS Biomaterials Science & Engineering
T1  - Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035
VL  - 7
IS  - 7
UR  - https://hdl.handle.net/21.15107/rcub_dais_11740
ER  - 
@misc{
author = "Pantović-Pavlović, Marijana and Stanojević, Boris and Pavlović, Miroslav M. and Mihailović, Marija D. and Stevanović, Jasmina and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. Supplementary information: The ANOVA results of antimicrobial activity on S. aureus are shown in Table S1 and the ANOVA results of antimicrobial activity on P. aeruginosa are shown in Table S2. The analysis showed significant difference at the 5% level of confidence.",
publisher = "American Chemical Society (ACS)",
journal = "ACS Biomaterials Science & Engineering",
title = "Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035",
volume = "7",
number = "7",
url = "https://hdl.handle.net/21.15107/rcub_dais_11740"
}
Pantović-Pavlović, M., Stanojević, B., Pavlović, M. M., Mihailović, M. D., Stevanović, J., Panić, V. V.,& Ignjatović, N.. (2021). Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035. in ACS Biomaterials Science & Engineering
American Chemical Society (ACS)., 7(7).
https://hdl.handle.net/21.15107/rcub_dais_11740
Pantović-Pavlović M, Stanojević B, Pavlović MM, Mihailović MD, Stevanović J, Panić VV, Ignjatović N. Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035. in ACS Biomaterials Science & Engineering. 2021;7(7).
https://hdl.handle.net/21.15107/rcub_dais_11740 .
Pantović-Pavlović, Marijana, Stanojević, Boris, Pavlović, Miroslav M., Mihailović, Marija D., Stevanović, Jasmina, Panić, Vladimir V., Ignjatović, Nenad, "Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035" in ACS Biomaterials Science & Engineering, 7, no. 7 (2021),
https://hdl.handle.net/21.15107/rcub_dais_11740 .

Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics

Degli Esposti, Lorenzo; Marković, Smilja; Ignjatović, Nenad; Panseri, Silvia; Montesi, Monica; Adamiano, Alessio; Fosca, Marco; Rau, Julietta V.; Uskoković, Vuk; Iafisco, Michele

(Royal Society of Chemistry, 2021)

TY  - JOUR
AU  - Degli Esposti, Lorenzo
AU  - Marković, Smilja
AU  - Ignjatović, Nenad
AU  - Panseri, Silvia
AU  - Montesi, Monica
AU  - Adamiano, Alessio
AU  - Fosca, Marco
AU  - Rau, Julietta V.
AU  - Uskoković, Vuk
AU  - Iafisco, Michele
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11639
AB  - Amorphous calcium phosphate (ACP) is a material of high interest for dentistry, orthopedics, and other biomedical sectors. Being intrinsically metastable, the process of transformation of ACP into a crystalline phase upon heating is of high relevance for the development of innovative bioceramics. Here we have first studied the thermal behavior of a citrate-stabilized ACP (Cit-ACP) also doped with fluoride ions (Cit-FACP) prepared at three different nominal Cit/Ca ratios (i.e. 4, 2, 1) by differential thermal analysis. Next, the physico-chemical features of the crystalline products as well as the in vitro cell response to the materials were investigated. A citrate and fluoride free ACP sample was also tested as the blank. We have found that the activation energy of crystallization of Cit-(F)ACP samples is lower in comparison to the blank ACP and this is influenced by the nominal Cit/Ca molar ratio. Interestingly, we have discovered that the thermal treatment of Cit-(F)ACP at 800 °C yields hydroxyapatite (HA) or fluorapatite (FHA) as the main products differently from blank ACP that, like most of the ACPs reported in the literature, yields β-tricalcium phosphate. This was attributed to the Ca/P ratio of Cit-(F)ACP, which is similar to HA. A study of the crystalline products has revealed that all the (F)HA samples were non-cytotoxic, and retained carbonate ions in the crystal structure despite the heat treatment that should have induced decarbonation. The morphology of the products is influenced by the nominal Cit/Ca ratio and the presence of fluoride, ranging from spherical nanoparticles to micrometric hexagonal rods. Overall, our results prove that the thermal crystallization of Cit-(F)ACP is markedly different from classic ACP based materials and the thermal treatment of Cit-(F)ACP represents an attractive route for producing pure bioactive HA ceramics.
PB  - Royal Society of Chemistry
T2  - Journal of Materials Chemistry B
T1  - Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics
SP  - 4832
EP  - 4845
VL  - 9
IS  - 24
DO  - 10.1039/D1TB00601K
UR  - https://hdl.handle.net/21.15107/rcub_dais_11639
ER  - 
@article{
author = "Degli Esposti, Lorenzo and Marković, Smilja and Ignjatović, Nenad and Panseri, Silvia and Montesi, Monica and Adamiano, Alessio and Fosca, Marco and Rau, Julietta V. and Uskoković, Vuk and Iafisco, Michele",
year = "2021",
abstract = "Amorphous calcium phosphate (ACP) is a material of high interest for dentistry, orthopedics, and other biomedical sectors. Being intrinsically metastable, the process of transformation of ACP into a crystalline phase upon heating is of high relevance for the development of innovative bioceramics. Here we have first studied the thermal behavior of a citrate-stabilized ACP (Cit-ACP) also doped with fluoride ions (Cit-FACP) prepared at three different nominal Cit/Ca ratios (i.e. 4, 2, 1) by differential thermal analysis. Next, the physico-chemical features of the crystalline products as well as the in vitro cell response to the materials were investigated. A citrate and fluoride free ACP sample was also tested as the blank. We have found that the activation energy of crystallization of Cit-(F)ACP samples is lower in comparison to the blank ACP and this is influenced by the nominal Cit/Ca molar ratio. Interestingly, we have discovered that the thermal treatment of Cit-(F)ACP at 800 °C yields hydroxyapatite (HA) or fluorapatite (FHA) as the main products differently from blank ACP that, like most of the ACPs reported in the literature, yields β-tricalcium phosphate. This was attributed to the Ca/P ratio of Cit-(F)ACP, which is similar to HA. A study of the crystalline products has revealed that all the (F)HA samples were non-cytotoxic, and retained carbonate ions in the crystal structure despite the heat treatment that should have induced decarbonation. The morphology of the products is influenced by the nominal Cit/Ca ratio and the presence of fluoride, ranging from spherical nanoparticles to micrometric hexagonal rods. Overall, our results prove that the thermal crystallization of Cit-(F)ACP is markedly different from classic ACP based materials and the thermal treatment of Cit-(F)ACP represents an attractive route for producing pure bioactive HA ceramics.",
publisher = "Royal Society of Chemistry",
journal = "Journal of Materials Chemistry B",
title = "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics",
pages = "4832-4845",
volume = "9",
number = "24",
doi = "10.1039/D1TB00601K",
url = "https://hdl.handle.net/21.15107/rcub_dais_11639"
}
Degli Esposti, L., Marković, S., Ignjatović, N., Panseri, S., Montesi, M., Adamiano, A., Fosca, M., Rau, J. V., Uskoković, V.,& Iafisco, M.. (2021). Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics. in Journal of Materials Chemistry B
Royal Society of Chemistry., 9(24), 4832-4845.
https://doi.org/10.1039/D1TB00601K
https://hdl.handle.net/21.15107/rcub_dais_11639
Degli Esposti L, Marković S, Ignjatović N, Panseri S, Montesi M, Adamiano A, Fosca M, Rau JV, Uskoković V, Iafisco M. Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics. in Journal of Materials Chemistry B. 2021;9(24):4832-4845.
doi:10.1039/D1TB00601K
https://hdl.handle.net/21.15107/rcub_dais_11639 .
Degli Esposti, Lorenzo, Marković, Smilja, Ignjatović, Nenad, Panseri, Silvia, Montesi, Monica, Adamiano, Alessio, Fosca, Marco, Rau, Julietta V., Uskoković, Vuk, Iafisco, Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics" in Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845,
https://doi.org/10.1039/D1TB00601K .,
https://hdl.handle.net/21.15107/rcub_dais_11639 .
3
5
2

Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics

Degli Esposti, Lorenzo; Marković, Smilja; Ignjatović, Nenad; Panseri, Silvia; Montesi, Monica; Adamiano, Alessio; Fosca, Marco; Rau, Julietta V.; Uskoković, Vuk; Iafisco, Michele

(Royal Society of Chemistry, 2021)

TY  - JOUR
AU  - Degli Esposti, Lorenzo
AU  - Marković, Smilja
AU  - Ignjatović, Nenad
AU  - Panseri, Silvia
AU  - Montesi, Monica
AU  - Adamiano, Alessio
AU  - Fosca, Marco
AU  - Rau, Julietta V.
AU  - Uskoković, Vuk
AU  - Iafisco, Michele
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11640
AB  - Amorphous calcium phosphate (ACP) is a material of high interest for dentistry, orthopedics, and other biomedical sectors. Being intrinsically metastable, the process of transformation of ACP into a crystalline phase upon heating is of high relevance for the development of innovative bioceramics. Here we have first studied the thermal behavior of a citrate-stabilized ACP (Cit-ACP) also doped with fluoride ions (Cit-FACP) prepared at three different nominal Cit/Ca ratios (i.e. 4, 2, 1) by differential thermal analysis. Next, the physico-chemical features of the crystalline products as well as the in vitro cell response to the materials were investigated. A citrate and fluoride free ACP sample was also tested as the blank. We have found that the activation energy of crystallization of Cit-(F)ACP samples is lower in comparison to the blank ACP and this is influenced by the nominal Cit/Ca molar ratio. Interestingly, we have discovered that the thermal treatment of Cit-(F)ACP at 800 °C yields hydroxyapatite (HA) or fluorapatite (FHA) as the main products differently from blank ACP that, like most of the ACPs reported in the literature, yields β-tricalcium phosphate. This was attributed to the Ca/P ratio of Cit-(F)ACP, which is similar to HA. A study of the crystalline products has revealed that all the (F)HA samples were non-cytotoxic, and retained carbonate ions in the crystal structure despite the heat treatment that should have induced decarbonation. The morphology of the products is influenced by the nominal Cit/Ca ratio and the presence of fluoride, ranging from spherical nanoparticles to micrometric hexagonal rods. Overall, our results prove that the thermal crystallization of Cit-(F)ACP is markedly different from classic ACP based materials and the thermal treatment of Cit-(F)ACP represents an attractive route for producing pure bioactive HA ceramics.
PB  - Royal Society of Chemistry
T2  - Journal of Materials Chemistry B
T1  - Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics
SP  - 4832
EP  - 4845
VL  - 9
IS  - 24
DO  - 10.1039/D1TB00601K
UR  - https://hdl.handle.net/21.15107/rcub_dais_11640
ER  - 
@article{
author = "Degli Esposti, Lorenzo and Marković, Smilja and Ignjatović, Nenad and Panseri, Silvia and Montesi, Monica and Adamiano, Alessio and Fosca, Marco and Rau, Julietta V. and Uskoković, Vuk and Iafisco, Michele",
year = "2021",
abstract = "Amorphous calcium phosphate (ACP) is a material of high interest for dentistry, orthopedics, and other biomedical sectors. Being intrinsically metastable, the process of transformation of ACP into a crystalline phase upon heating is of high relevance for the development of innovative bioceramics. Here we have first studied the thermal behavior of a citrate-stabilized ACP (Cit-ACP) also doped with fluoride ions (Cit-FACP) prepared at three different nominal Cit/Ca ratios (i.e. 4, 2, 1) by differential thermal analysis. Next, the physico-chemical features of the crystalline products as well as the in vitro cell response to the materials were investigated. A citrate and fluoride free ACP sample was also tested as the blank. We have found that the activation energy of crystallization of Cit-(F)ACP samples is lower in comparison to the blank ACP and this is influenced by the nominal Cit/Ca molar ratio. Interestingly, we have discovered that the thermal treatment of Cit-(F)ACP at 800 °C yields hydroxyapatite (HA) or fluorapatite (FHA) as the main products differently from blank ACP that, like most of the ACPs reported in the literature, yields β-tricalcium phosphate. This was attributed to the Ca/P ratio of Cit-(F)ACP, which is similar to HA. A study of the crystalline products has revealed that all the (F)HA samples were non-cytotoxic, and retained carbonate ions in the crystal structure despite the heat treatment that should have induced decarbonation. The morphology of the products is influenced by the nominal Cit/Ca ratio and the presence of fluoride, ranging from spherical nanoparticles to micrometric hexagonal rods. Overall, our results prove that the thermal crystallization of Cit-(F)ACP is markedly different from classic ACP based materials and the thermal treatment of Cit-(F)ACP represents an attractive route for producing pure bioactive HA ceramics.",
publisher = "Royal Society of Chemistry",
journal = "Journal of Materials Chemistry B",
title = "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics",
pages = "4832-4845",
volume = "9",
number = "24",
doi = "10.1039/D1TB00601K",
url = "https://hdl.handle.net/21.15107/rcub_dais_11640"
}
Degli Esposti, L., Marković, S., Ignjatović, N., Panseri, S., Montesi, M., Adamiano, A., Fosca, M., Rau, J. V., Uskoković, V.,& Iafisco, M.. (2021). Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics. in Journal of Materials Chemistry B
Royal Society of Chemistry., 9(24), 4832-4845.
https://doi.org/10.1039/D1TB00601K
https://hdl.handle.net/21.15107/rcub_dais_11640
Degli Esposti L, Marković S, Ignjatović N, Panseri S, Montesi M, Adamiano A, Fosca M, Rau JV, Uskoković V, Iafisco M. Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics. in Journal of Materials Chemistry B. 2021;9(24):4832-4845.
doi:10.1039/D1TB00601K
https://hdl.handle.net/21.15107/rcub_dais_11640 .
Degli Esposti, Lorenzo, Marković, Smilja, Ignjatović, Nenad, Panseri, Silvia, Montesi, Monica, Adamiano, Alessio, Fosca, Marco, Rau, Julietta V., Uskoković, Vuk, Iafisco, Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics" in Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845,
https://doi.org/10.1039/D1TB00601K .,
https://hdl.handle.net/21.15107/rcub_dais_11640 .
3
5
2

Electronic Supplementary Information associated with the article: Degli Esposti Lorenzo, Marković Smilja, Ignjatović Nenad, Panseri Silvia, Montesi Monica, Adamiano Alessio, Fosca Marco, Rau Julietta V., Uskoković Vuk, Iafisco Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics." Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845, https://doi.org/10.1039/D1TB00601K

Degli Esposti, Lorenzo; Marković, Smilja; Ignjatović, Nenad; Panseri, Silvia; Montesi, Monica; Adamiano, Alessio; Fosca, Marco; Rau, Julietta V.; Uskoković, Vuk; Iafisco, Michele

(Royal Society of Chemistry, 2021)

TY  - DATA
AU  - Degli Esposti, Lorenzo
AU  - Marković, Smilja
AU  - Ignjatović, Nenad
AU  - Panseri, Silvia
AU  - Montesi, Monica
AU  - Adamiano, Alessio
AU  - Fosca, Marco
AU  - Rau, Julietta V.
AU  - Uskoković, Vuk
AU  - Iafisco, Michele
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11642
AB  - Figure S1. The shift in the crystallization peak for (A) Cit-ACP-1 and (B) Cit-FACP-1 to higher temperatures in direct proportion with the heating rate; Figure S2. TGA curves of calcined Cit-ACP-4, Cit-ACP-2, and Cit-ACP-1; Figure S3. Pictures of calcined (A) Cit-ACP-4 and (B) Cit-ACP-1
PB  - Royal Society of Chemistry
T2  - Journal of Materials Chemistry B
T1  - Electronic Supplementary Information associated with the article: Degli Esposti Lorenzo, Marković Smilja, Ignjatović Nenad, Panseri Silvia, Montesi Monica, Adamiano Alessio, Fosca Marco, Rau Julietta V., Uskoković Vuk, Iafisco Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics." Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845, https://doi.org/10.1039/D1TB00601K
VL  - 9
IS  - 24
UR  - https://hdl.handle.net/21.15107/rcub_dais_11642
ER  - 
@misc{
author = "Degli Esposti, Lorenzo and Marković, Smilja and Ignjatović, Nenad and Panseri, Silvia and Montesi, Monica and Adamiano, Alessio and Fosca, Marco and Rau, Julietta V. and Uskoković, Vuk and Iafisco, Michele",
year = "2021",
abstract = "Figure S1. The shift in the crystallization peak for (A) Cit-ACP-1 and (B) Cit-FACP-1 to higher temperatures in direct proportion with the heating rate; Figure S2. TGA curves of calcined Cit-ACP-4, Cit-ACP-2, and Cit-ACP-1; Figure S3. Pictures of calcined (A) Cit-ACP-4 and (B) Cit-ACP-1",
publisher = "Royal Society of Chemistry",
journal = "Journal of Materials Chemistry B",
title = "Electronic Supplementary Information associated with the article: Degli Esposti Lorenzo, Marković Smilja, Ignjatović Nenad, Panseri Silvia, Montesi Monica, Adamiano Alessio, Fosca Marco, Rau Julietta V., Uskoković Vuk, Iafisco Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics." Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845, https://doi.org/10.1039/D1TB00601K",
volume = "9",
number = "24",
url = "https://hdl.handle.net/21.15107/rcub_dais_11642"
}
Degli Esposti, L., Marković, S., Ignjatović, N., Panseri, S., Montesi, M., Adamiano, A., Fosca, M., Rau, J. V., Uskoković, V.,& Iafisco, M.. (2021). Electronic Supplementary Information associated with the article: Degli Esposti Lorenzo, Marković Smilja, Ignjatović Nenad, Panseri Silvia, Montesi Monica, Adamiano Alessio, Fosca Marco, Rau Julietta V., Uskoković Vuk, Iafisco Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics." Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845, https://doi.org/10.1039/D1TB00601K. in Journal of Materials Chemistry B
Royal Society of Chemistry., 9(24).
https://hdl.handle.net/21.15107/rcub_dais_11642
Degli Esposti L, Marković S, Ignjatović N, Panseri S, Montesi M, Adamiano A, Fosca M, Rau JV, Uskoković V, Iafisco M. Electronic Supplementary Information associated with the article: Degli Esposti Lorenzo, Marković Smilja, Ignjatović Nenad, Panseri Silvia, Montesi Monica, Adamiano Alessio, Fosca Marco, Rau Julietta V., Uskoković Vuk, Iafisco Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics." Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845, https://doi.org/10.1039/D1TB00601K. in Journal of Materials Chemistry B. 2021;9(24).
https://hdl.handle.net/21.15107/rcub_dais_11642 .
Degli Esposti, Lorenzo, Marković, Smilja, Ignjatović, Nenad, Panseri, Silvia, Montesi, Monica, Adamiano, Alessio, Fosca, Marco, Rau, Julietta V., Uskoković, Vuk, Iafisco, Michele, "Electronic Supplementary Information associated with the article: Degli Esposti Lorenzo, Marković Smilja, Ignjatović Nenad, Panseri Silvia, Montesi Monica, Adamiano Alessio, Fosca Marco, Rau Julietta V., Uskoković Vuk, Iafisco Michele, "Thermal crystallization of amorphous calcium phosphate combined with citrate and fluoride doping: a novel route to produce hydroxyapatite bioceramics." Journal of Materials Chemistry B, 9, no. 24 (2021):4832-4845, https://doi.org/10.1039/D1TB00601K" in Journal of Materials Chemistry B, 9, no. 24 (2021),
https://hdl.handle.net/21.15107/rcub_dais_11642 .

Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate

Pantović Pavlović, Marijana R.; Pavlović, Miroslav M.; Eraković, Sanja; Stevanović, Jasmina S.; Panić, Vladimir V.; Ignjatović, Nenad

(Elsevier, 2020)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2020
UR  - http://www.sciencedirect.com/science/article/pii/S0167577X19317537
UR  - https://dais.sanu.ac.rs/123456789/6915
AB  - In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.
PB  - Elsevier
T2  - Materials Letters
T1  - Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate
SP  - 127121
VL  - 261
DO  - 10.1016/j.matlet.2019.127121
UR  - https://hdl.handle.net/21.15107/rcub_dais_6915
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2020",
abstract = "In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.",
publisher = "Elsevier",
journal = "Materials Letters",
title = "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate",
pages = "127121",
volume = "261",
doi = "10.1016/j.matlet.2019.127121",
url = "https://hdl.handle.net/21.15107/rcub_dais_6915"
}
Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2020). Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters
Elsevier., 261, 127121.
https://doi.org/10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6915
Pantović Pavlović MR, Pavlović MM, Eraković S, Stevanović JS, Panić VV, Ignjatović N. Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters. 2020;261:127121.
doi:10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6915 .
Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate" in Materials Letters, 261 (2020):127121,
https://doi.org/10.1016/j.matlet.2019.127121 .,
https://hdl.handle.net/21.15107/rcub_dais_6915 .
4
3
5

Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate

Pantović Pavlović, Marijana R.; Pavlović, Miroslav M.; Eraković, Sanja; Stevanović, Jasmina S.; Panić, Vladimir V.; Ignjatović, Nenad

(Elsevier, 2020)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2020
UR  - http://www.sciencedirect.com/science/article/pii/S0167577X19317537
UR  - https://dais.sanu.ac.rs/123456789/6914
AB  - In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.
PB  - Elsevier
T2  - Materials Letters
T1  - Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate
SP  - 127121
VL  - 261
DO  - 10.1016/j.matlet.2019.127121
UR  - https://hdl.handle.net/21.15107/rcub_dais_6914
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2020",
abstract = "In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.",
publisher = "Elsevier",
journal = "Materials Letters",
title = "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate",
pages = "127121",
volume = "261",
doi = "10.1016/j.matlet.2019.127121",
url = "https://hdl.handle.net/21.15107/rcub_dais_6914"
}
Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2020). Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters
Elsevier., 261, 127121.
https://doi.org/10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6914
Pantović Pavlović MR, Pavlović MM, Eraković S, Stevanović JS, Panić VV, Ignjatović N. Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters. 2020;261:127121.
doi:10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6914 .
Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate" in Materials Letters, 261 (2020):127121,
https://doi.org/10.1016/j.matlet.2019.127121 .,
https://hdl.handle.net/21.15107/rcub_dais_6914 .
4
5

Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment

Ristovski (Trifunović), Jovana; Žižak, Željko; Marković, Smilja; Janković, Nenad; Ignjatović, Nenad

(Royal Society of Chemistry, 2020)

TY  - JOUR
AU  - Ristovski (Trifunović), Jovana
AU  - Žižak, Željko
AU  - Marković, Smilja
AU  - Janković, Nenad
AU  - Ignjatović, Nenad
PY  - 2020
UR  - https://pubs.rsc.org/en/content/articlelanding/2020/ra/d0ra08085c
UR  - https://dais.sanu.ac.rs/123456789/9814
AB  - Tetrahydropyrimidines are a class of azaheterocycles, also called Biginelli hybrids (obtained from the Biginelli reaction), that have attracted an enormous interest in the medicinal chemistry community in recent years, due to a broad biological activity, such as anticancer, antiviral, anti-inflammatory, antidiabetic, antituberculosis activities, etc. According to SciFinder®, more than 70 000 different Biginelli-like compounds have been covered in publications. However, although the Biginelli reaction can yield a large number of compounds with a broad range of activities, none of them have been captured in a carrier. In this study, chitosan-based (Ch) nanoparticles (NPs) containing three different molecules (Biginelli hybrids) were developed and tested for the first time as simple and promising vehicles for anticancer Biginelli-based drugs. The key features of NPs, such as size, surface morphology, drug encapsulation efficiency, and in vitro release were systematically investigated. Rather weak cell selectivity of pure Biginelli hybrids (A–C) to selected cancer cell lines has improved and this has been accompanied with two-to-four times stronger cytotoxic effect of A–C loaded Ch NPs, with a triple reduction in toxicity to healthy cells (MRC-5). It has been observed that the examined NPs induce apoptosis. The cell cycle analysis has confirmed the influence of A-loaded Ch (A-Ch), B-loaded Ch (B-Ch), and C-loaded Ch (C-Ch) on the cell cycle distribution, which was homogenously affected. This is the difference with regard to the effect of A, B, and C on the cell cycle. It has been established that the increased selectivity and antitumor activity of NPs are related to the presence of the carrier.
PB  - Royal Society of Chemistry
T2  - RSC Advances
T1  - Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment
SP  - 41542
EP  - 41550
VL  - 10
IS  - 68
DO  - 10.1039/D0RA08085C
UR  - https://hdl.handle.net/21.15107/rcub_dais_9814
ER  - 
@article{
author = "Ristovski (Trifunović), Jovana and Žižak, Željko and Marković, Smilja and Janković, Nenad and Ignjatović, Nenad",
year = "2020",
abstract = "Tetrahydropyrimidines are a class of azaheterocycles, also called Biginelli hybrids (obtained from the Biginelli reaction), that have attracted an enormous interest in the medicinal chemistry community in recent years, due to a broad biological activity, such as anticancer, antiviral, anti-inflammatory, antidiabetic, antituberculosis activities, etc. According to SciFinder®, more than 70 000 different Biginelli-like compounds have been covered in publications. However, although the Biginelli reaction can yield a large number of compounds with a broad range of activities, none of them have been captured in a carrier. In this study, chitosan-based (Ch) nanoparticles (NPs) containing three different molecules (Biginelli hybrids) were developed and tested for the first time as simple and promising vehicles for anticancer Biginelli-based drugs. The key features of NPs, such as size, surface morphology, drug encapsulation efficiency, and in vitro release were systematically investigated. Rather weak cell selectivity of pure Biginelli hybrids (A–C) to selected cancer cell lines has improved and this has been accompanied with two-to-four times stronger cytotoxic effect of A–C loaded Ch NPs, with a triple reduction in toxicity to healthy cells (MRC-5). It has been observed that the examined NPs induce apoptosis. The cell cycle analysis has confirmed the influence of A-loaded Ch (A-Ch), B-loaded Ch (B-Ch), and C-loaded Ch (C-Ch) on the cell cycle distribution, which was homogenously affected. This is the difference with regard to the effect of A, B, and C on the cell cycle. It has been established that the increased selectivity and antitumor activity of NPs are related to the presence of the carrier.",
publisher = "Royal Society of Chemistry",
journal = "RSC Advances",
title = "Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment",
pages = "41542-41550",
volume = "10",
number = "68",
doi = "10.1039/D0RA08085C",
url = "https://hdl.handle.net/21.15107/rcub_dais_9814"
}
Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N.,& Ignjatović, N.. (2020). Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. in RSC Advances
Royal Society of Chemistry., 10(68), 41542-41550.
https://doi.org/10.1039/D0RA08085C
https://hdl.handle.net/21.15107/rcub_dais_9814
Ristovski (Trifunović) J, Žižak Ž, Marković S, Janković N, Ignjatović N. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. in RSC Advances. 2020;10(68):41542-41550.
doi:10.1039/D0RA08085C
https://hdl.handle.net/21.15107/rcub_dais_9814 .
Ristovski (Trifunović), Jovana, Žižak, Željko, Marković, Smilja, Janković, Nenad, Ignjatović, Nenad, "Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment" in RSC Advances, 10, no. 68 (2020):41542-41550,
https://doi.org/10.1039/D0RA08085C .,
https://hdl.handle.net/21.15107/rcub_dais_9814 .
1

Electronic Supplementary Information associated with the paper: Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N., Ignjatović, N., 2020. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. RSC Adv. 10, 41542–41550. https://doi.org/10.1039/D0RA08085C

Ristovski (Trifunović), Jovana; Žižak, Željko; Marković, Smilja; Janković, Nenad; Ignjatović, Nenad

(Royal Society of Chemistry, 2020)

TY  - DATA
AU  - Ristovski (Trifunović), Jovana
AU  - Žižak, Željko
AU  - Marković, Smilja
AU  - Janković, Nenad
AU  - Ignjatović, Nenad
PY  - 2020
UR  - https://dais.sanu.ac.rs/123456789/9815
PB  - Royal Society of Chemistry
T2  - RSC Advances
T1  - Electronic Supplementary Information associated with the paper: Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N., Ignjatović, N., 2020. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. RSC Adv. 10, 41542–41550. https://doi.org/10.1039/D0RA08085C
VL  - 10
IS  - 68
UR  - https://hdl.handle.net/21.15107/rcub_dais_9815
ER  - 
@misc{
author = "Ristovski (Trifunović), Jovana and Žižak, Željko and Marković, Smilja and Janković, Nenad and Ignjatović, Nenad",
year = "2020",
publisher = "Royal Society of Chemistry",
journal = "RSC Advances",
title = "Electronic Supplementary Information associated with the paper: Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N., Ignjatović, N., 2020. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. RSC Adv. 10, 41542–41550. https://doi.org/10.1039/D0RA08085C",
volume = "10",
number = "68",
url = "https://hdl.handle.net/21.15107/rcub_dais_9815"
}
Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N.,& Ignjatović, N.. (2020). Electronic Supplementary Information associated with the paper: Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N., Ignjatović, N., 2020. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. RSC Adv. 10, 41542–41550. https://doi.org/10.1039/D0RA08085C. in RSC Advances
Royal Society of Chemistry., 10(68).
https://hdl.handle.net/21.15107/rcub_dais_9815
Ristovski (Trifunović) J, Žižak Ž, Marković S, Janković N, Ignjatović N. Electronic Supplementary Information associated with the paper: Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N., Ignjatović, N., 2020. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. RSC Adv. 10, 41542–41550. https://doi.org/10.1039/D0RA08085C. in RSC Advances. 2020;10(68).
https://hdl.handle.net/21.15107/rcub_dais_9815 .
Ristovski (Trifunović), Jovana, Žižak, Željko, Marković, Smilja, Janković, Nenad, Ignjatović, Nenad, "Electronic Supplementary Information associated with the paper: Ristovski (Trifunović), J., Žižak, Ž., Marković, S., Janković, N., Ignjatović, N., 2020. Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment. RSC Adv. 10, 41542–41550. https://doi.org/10.1039/D0RA08085C" in RSC Advances, 10, no. 68 (2020),
https://hdl.handle.net/21.15107/rcub_dais_9815 .

From molecules to nanoparticles to functional materials

Ignjatović, Nenad; Marković, Smilja; Jugović, Dragana; Uskoković, Vuk; Uskoković, Dragan

(Belgrade : Serbian Chemical Society, 2020)

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Marković, Smilja
AU  - Jugović, Dragana
AU  - Uskoković, Vuk
AU  - Uskoković, Dragan
PY  - 2020
UR  - https://dais.sanu.ac.rs/123456789/10037
AB  - Functional nanomaterials have held a steady position at the frontier of materials science and engineering in the 21st century. “Molecular Designing of Nanoparticles with Controlled Morphological and Physicochemical Characteristics and Functional Materials Based on Them” was the title of the research project funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia and performed between 2011 and 2019 in the interdisciplinary area of nanoscience and nanotechnologies. Research activities within this program were divided into five interrelated topics: 1) from molecules to nanoparticles; 2) advanced ceramics with improved functional properties; 3) electrode materials for lithium–ion batteries; 4) nano-calcium phosphate in preventive and regenerative medicine; 5) biodegradable microand nano-particles for the controlled delivery of medicaments. This report gives an insight into this bibliographically most impactful Serbian national project on nanotechnologies executed within the aforementioned nine-year cycle, 2011–2019, focusing here only on the results achieved in the past three years. The project provided an outstanding and internationally recognized contribution to synthesis, characterization and functional design of a number of materials systems, including pure and lanthanide–doped hydroxyapatite, zinc oxides, sodium cobaltates, lithium iron pyrophosphates, lithium iron silicates and a number of polymeric systems.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - From molecules to nanoparticles to functional materials
SP  - 1383
EP  - 1403
VL  - 85
IS  - 11
DO  - 10.2298/JSC200426035I
UR  - https://hdl.handle.net/21.15107/rcub_dais_10037
ER  - 
@article{
author = "Ignjatović, Nenad and Marković, Smilja and Jugović, Dragana and Uskoković, Vuk and Uskoković, Dragan",
year = "2020",
abstract = "Functional nanomaterials have held a steady position at the frontier of materials science and engineering in the 21st century. “Molecular Designing of Nanoparticles with Controlled Morphological and Physicochemical Characteristics and Functional Materials Based on Them” was the title of the research project funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia and performed between 2011 and 2019 in the interdisciplinary area of nanoscience and nanotechnologies. Research activities within this program were divided into five interrelated topics: 1) from molecules to nanoparticles; 2) advanced ceramics with improved functional properties; 3) electrode materials for lithium–ion batteries; 4) nano-calcium phosphate in preventive and regenerative medicine; 5) biodegradable microand nano-particles for the controlled delivery of medicaments. This report gives an insight into this bibliographically most impactful Serbian national project on nanotechnologies executed within the aforementioned nine-year cycle, 2011–2019, focusing here only on the results achieved in the past three years. The project provided an outstanding and internationally recognized contribution to synthesis, characterization and functional design of a number of materials systems, including pure and lanthanide–doped hydroxyapatite, zinc oxides, sodium cobaltates, lithium iron pyrophosphates, lithium iron silicates and a number of polymeric systems.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "From molecules to nanoparticles to functional materials",
pages = "1383-1403",
volume = "85",
number = "11",
doi = "10.2298/JSC200426035I",
url = "https://hdl.handle.net/21.15107/rcub_dais_10037"
}
Ignjatović, N., Marković, S., Jugović, D., Uskoković, V.,& Uskoković, D.. (2020). From molecules to nanoparticles to functional materials. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 85(11), 1383-1403.
https://doi.org/10.2298/JSC200426035I
https://hdl.handle.net/21.15107/rcub_dais_10037
Ignjatović N, Marković S, Jugović D, Uskoković V, Uskoković D. From molecules to nanoparticles to functional materials. in Journal of the Serbian Chemical Society. 2020;85(11):1383-1403.
doi:10.2298/JSC200426035I
https://hdl.handle.net/21.15107/rcub_dais_10037 .
Ignjatović, Nenad, Marković, Smilja, Jugović, Dragana, Uskoković, Vuk, Uskoković, Dragan, "From molecules to nanoparticles to functional materials" in Journal of the Serbian Chemical Society, 85, no. 11 (2020):1383-1403,
https://doi.org/10.2298/JSC200426035I .,
https://hdl.handle.net/21.15107/rcub_dais_10037 .

Influence of the Shape of Copper Powder Particles on the Crystal Structure and Some Decisive Characteristics of the Metal Powders

Avramović, Ljiljana; Maksimović, Vesna M.; Baščarević, Zvezdana; Ignjatović, Nenad; Bugarin, Mile; Marković, Radmila; Nikolić, Nebojša D.

(Basel : MDPI, 2019)

TY  - JOUR
AU  - Avramović, Ljiljana
AU  - Maksimović, Vesna M.
AU  - Baščarević, Zvezdana
AU  - Ignjatović, Nenad
AU  - Bugarin, Mile
AU  - Marković, Radmila
AU  - Nikolić, Nebojša D.
PY  - 2019
UR  - https://www.mdpi.com/2075-4701/9/1/56
UR  - https://dais.sanu.ac.rs/123456789/4770
AB  - Three different forms of Cu powder particles obtained by either galvanostatic electrolysis or a non-electrolytic method were analyzed by a scanning electron microscope (SEM), X-ray diffraction (XRD) and particle size distribution (PSD). Electrolytic procedures were performed under different hydrogen evolution conditions, leading to the formation of either 3D branched dendrites or disperse cauliflower-like particles. The third type of particles were compact agglomerates of the Cu grains, whose structural characteristics indicated that they were formed by a non-electrolytic method. Unlike the sharp tips that characterize the usual form of Cu dendrites, the ends of both the trunk and branches were globules in the formed dendrites, indicating that a novel type of Cu dendrites was formed in this investigation. Although the macro structures of the particles were extremely varied, they had very similar micro structures because they were constructed by spherical grains. The Cu crystallites were randomly oriented in the dendrites and compact agglomerates of the Cu grains, while the disperse cauliflower-like particles showed (220) and (311) preferred orientation. This indicates that the applied current density affects not only the morphology of the particles, but also their crystal structure. The best performance, defined by the largest specific surface area and the smallest particle size, was by the galvanostatically produced powder consisting of disperse cauliflower-like particles.
PB  - Basel : MDPI
T2  - Metals
T1  - Influence of the Shape of Copper Powder Particles on the Crystal Structure and Some Decisive Characteristics of the Metal Powders
SP  - 56
VL  - 9
IS  - 1
DO  - 10.3390/met9010056
UR  - https://hdl.handle.net/21.15107/rcub_dais_4770
ER  - 
@article{
author = "Avramović, Ljiljana and Maksimović, Vesna M. and Baščarević, Zvezdana and Ignjatović, Nenad and Bugarin, Mile and Marković, Radmila and Nikolić, Nebojša D.",
year = "2019",
abstract = "Three different forms of Cu powder particles obtained by either galvanostatic electrolysis or a non-electrolytic method were analyzed by a scanning electron microscope (SEM), X-ray diffraction (XRD) and particle size distribution (PSD). Electrolytic procedures were performed under different hydrogen evolution conditions, leading to the formation of either 3D branched dendrites or disperse cauliflower-like particles. The third type of particles were compact agglomerates of the Cu grains, whose structural characteristics indicated that they were formed by a non-electrolytic method. Unlike the sharp tips that characterize the usual form of Cu dendrites, the ends of both the trunk and branches were globules in the formed dendrites, indicating that a novel type of Cu dendrites was formed in this investigation. Although the macro structures of the particles were extremely varied, they had very similar micro structures because they were constructed by spherical grains. The Cu crystallites were randomly oriented in the dendrites and compact agglomerates of the Cu grains, while the disperse cauliflower-like particles showed (220) and (311) preferred orientation. This indicates that the applied current density affects not only the morphology of the particles, but also their crystal structure. The best performance, defined by the largest specific surface area and the smallest particle size, was by the galvanostatically produced powder consisting of disperse cauliflower-like particles.",
publisher = "Basel : MDPI",
journal = "Metals",
title = "Influence of the Shape of Copper Powder Particles on the Crystal Structure and Some Decisive Characteristics of the Metal Powders",
pages = "56",
volume = "9",
number = "1",
doi = "10.3390/met9010056",
url = "https://hdl.handle.net/21.15107/rcub_dais_4770"
}
Avramović, L., Maksimović, V. M., Baščarević, Z., Ignjatović, N., Bugarin, M., Marković, R.,& Nikolić, N. D.. (2019). Influence of the Shape of Copper Powder Particles on the Crystal Structure and Some Decisive Characteristics of the Metal Powders. in Metals
Basel : MDPI., 9(1), 56.
https://doi.org/10.3390/met9010056
https://hdl.handle.net/21.15107/rcub_dais_4770
Avramović L, Maksimović VM, Baščarević Z, Ignjatović N, Bugarin M, Marković R, Nikolić ND. Influence of the Shape of Copper Powder Particles on the Crystal Structure and Some Decisive Characteristics of the Metal Powders. in Metals. 2019;9(1):56.
doi:10.3390/met9010056
https://hdl.handle.net/21.15107/rcub_dais_4770 .
Avramović, Ljiljana, Maksimović, Vesna M., Baščarević, Zvezdana, Ignjatović, Nenad, Bugarin, Mile, Marković, Radmila, Nikolić, Nebojša D., "Influence of the Shape of Copper Powder Particles on the Crystal Structure and Some Decisive Characteristics of the Metal Powders" in Metals, 9, no. 1 (2019):56,
https://doi.org/10.3390/met9010056 .,
https://hdl.handle.net/21.15107/rcub_dais_4770 .
12
15

Osteogenic differentiation of dental pulp stem cells influenced by synthesized calcium phosphate-based nanomaterial in vitro

Tomić, Milica; Stojanović, Sanja; Ignjatović, Nenad; Najman, Stevo

(Belgrade : Institute of Technical Sciences of SASA, 2019)

TY  - CONF
AU  - Tomić, Milica
AU  - Stojanović, Sanja
AU  - Ignjatović, Nenad
AU  - Najman, Stevo
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6969
AB  - Dental pulp stem cells (DPSCs) are mesenchymal stem cells that may have a versatile and abundant application in regenerative medicine and dentistry due to their availability, possibility of isolation from different types of teeth and potential to differentiate into several cell types. In recent years, there is an emerging trend of the use of nanomaterials in medicine and dentistry that, by virtue of their unique properties, have become very attractive as a tool for the treatment of bone tissue defects. The aim of our study was to examine the potential of synthesized nanomaterial, intended for bone tissue engineering and regenerative applications, biphasic calcium phosphate coated with poly-D,L-lactide-co-glycolide (CP/PLGA), to influence the osteogenic differentiation of DPSCs. Cells were obtained from the mature healthy teeth by outgrowth of the cells from undigested pulp pieces during culturing, in standard cell culture conditions. Cells were subjected to osteogenic differentiation for seven and 14 days by culturing the cells with two concentrations of CP/PLGA nanoparticles in the presence or absence of osteogenic supplements in the media. Osteogenic differentiation was assessed by phase contrast microscopy as well as by Von Kossa and Alizarin Red S staining of formed inorganic deposits. The results showed that CP/PLGA influenced osteogenesis in concentration-dependent manner and differently in osteogenic and standard cell culture media. The use of calcium phosphate-based nanomaterials in combination with DPSCs, under certain conditions, could be a promising approach in regenerative medicine and dentistry.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of abstracts / Eighteenth Young Researchers' Conference Materials Sciences and Engineering, December 4-6, 2019, Belgrade, Serbia
T1  - Osteogenic differentiation of dental pulp stem cells influenced by synthesized calcium phosphate-based nanomaterial in vitro
SP  - 4
EP  - 4
UR  - https://hdl.handle.net/21.15107/rcub_dais_6969
ER  - 
@conference{
author = "Tomić, Milica and Stojanović, Sanja and Ignjatović, Nenad and Najman, Stevo",
year = "2019",
abstract = "Dental pulp stem cells (DPSCs) are mesenchymal stem cells that may have a versatile and abundant application in regenerative medicine and dentistry due to their availability, possibility of isolation from different types of teeth and potential to differentiate into several cell types. In recent years, there is an emerging trend of the use of nanomaterials in medicine and dentistry that, by virtue of their unique properties, have become very attractive as a tool for the treatment of bone tissue defects. The aim of our study was to examine the potential of synthesized nanomaterial, intended for bone tissue engineering and regenerative applications, biphasic calcium phosphate coated with poly-D,L-lactide-co-glycolide (CP/PLGA), to influence the osteogenic differentiation of DPSCs. Cells were obtained from the mature healthy teeth by outgrowth of the cells from undigested pulp pieces during culturing, in standard cell culture conditions. Cells were subjected to osteogenic differentiation for seven and 14 days by culturing the cells with two concentrations of CP/PLGA nanoparticles in the presence or absence of osteogenic supplements in the media. Osteogenic differentiation was assessed by phase contrast microscopy as well as by Von Kossa and Alizarin Red S staining of formed inorganic deposits. The results showed that CP/PLGA influenced osteogenesis in concentration-dependent manner and differently in osteogenic and standard cell culture media. The use of calcium phosphate-based nanomaterials in combination with DPSCs, under certain conditions, could be a promising approach in regenerative medicine and dentistry.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of abstracts / Eighteenth Young Researchers' Conference Materials Sciences and Engineering, December 4-6, 2019, Belgrade, Serbia",
title = "Osteogenic differentiation of dental pulp stem cells influenced by synthesized calcium phosphate-based nanomaterial in vitro",
pages = "4-4",
url = "https://hdl.handle.net/21.15107/rcub_dais_6969"
}
Tomić, M., Stojanović, S., Ignjatović, N.,& Najman, S.. (2019). Osteogenic differentiation of dental pulp stem cells influenced by synthesized calcium phosphate-based nanomaterial in vitro. in Program and the Book of abstracts / Eighteenth Young Researchers' Conference Materials Sciences and Engineering, December 4-6, 2019, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 4-4.
https://hdl.handle.net/21.15107/rcub_dais_6969
Tomić M, Stojanović S, Ignjatović N, Najman S. Osteogenic differentiation of dental pulp stem cells influenced by synthesized calcium phosphate-based nanomaterial in vitro. in Program and the Book of abstracts / Eighteenth Young Researchers' Conference Materials Sciences and Engineering, December 4-6, 2019, Belgrade, Serbia. 2019;:4-4.
https://hdl.handle.net/21.15107/rcub_dais_6969 .
Tomić, Milica, Stojanović, Sanja, Ignjatović, Nenad, Najman, Stevo, "Osteogenic differentiation of dental pulp stem cells influenced by synthesized calcium phosphate-based nanomaterial in vitro" in Program and the Book of abstracts / Eighteenth Young Researchers' Conference Materials Sciences and Engineering, December 4-6, 2019, Belgrade, Serbia (2019):4-4,
https://hdl.handle.net/21.15107/rcub_dais_6969 .

Rare-earth (Gd 3+ ,Yb 3+ /Tm 3+ , Eu 3+ ) co-doped hydroxyapatite as magnetic, up-conversion and down-conversion materials for multimodal imaging

Ignjatović, Nenad; Mančić, Lidija; Vuković, Marina; Stojanović, Zoran S.; Nikolić, Marko G.; Škapin, Srečo Davor; Jovanović, Sonja; Veselinović, Ljiljana; Uskoković, Vuk; Lazić, Snežana; Marković, Smilja; Lazarević, Miloš M.; Uskoković, Dragan

(Springer Nature, 2019)

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Mančić, Lidija
AU  - Vuković, Marina
AU  - Stojanović, Zoran S.
AU  - Nikolić, Marko G.
AU  - Škapin, Srečo Davor
AU  - Jovanović, Sonja
AU  - Veselinović, Ljiljana
AU  - Uskoković, Vuk
AU  - Lazić, Snežana
AU  - Marković, Smilja
AU  - Lazarević, Miloš M.
AU  - Uskoković, Dragan
PY  - 2019
UR  - https://www.nature.com/articles/s41598-019-52885-0
UR  - https://dais.sanu.ac.rs/123456789/6950
AB  - Taking advantage of the flexibility of the apatite structure, nano- and micro-particles of hydroxyapatite (HAp) were doped with different combinations of rare earth ions (RE3+ = Gd, Eu, Yb, Tm) to achieve a synergy among their magnetic and optical properties and to enable their application in preventive medicine, particularly diagnostics based on multimodal imaging. All powders were synthesized through hydrothermal processing at T ≤ 200 °C. An X-ray powder diffraction analysis showed that all powders crystallized in P63/m space group of the hexagonal crystal structure. The refined unit-cell parameters reflected a decrease in the unit cell volume as a result of the partial substitution of Ca2+ with smaller RE3+ ions at both cation positions. The FTIR analysis additionally suggested that a synergy may exist solely in the triply doped system, where the lattice symmetry and vibration modes become more coherent than in the singly or doubly doped systems. HAp:RE3+ optical characterization revealed a change in the energy band gap and the appearance of a weak blue luminescence (λex = 370 nm) due to an increased concentration of defects. The “up”- and the “down”-conversion spectra of HAp:Gd/Yb/Tm and HAp:Gd/Eu powders showed characteristic transitions of Tm3+ and Eu3+, respectively. Furthermore, in contrast to diamagnetic HAp, all HAp:RE3+ powders exhibited paramagnetic behavior. Cell viability tests of HAp:Gd/Yb/Tm and HAp:Gd/Eu powders in human dental pulp stem cell cultures indicated their good biocompatibility.
PB  - Springer Nature
T2  - Scientific Reports
T1  - Rare-earth (Gd 3+ ,Yb 3+ /Tm 3+ , Eu 3+ ) co-doped hydroxyapatite as magnetic, up-conversion and down-conversion materials for multimodal imaging
SP  - 1
EP  - 15
VL  - 9
IS  - 1
DO  - 10.1038/s41598-019-52885-0
UR  - https://hdl.handle.net/21.15107/rcub_dais_6950
ER  - 
@article{
author = "Ignjatović, Nenad and Mančić, Lidija and Vuković, Marina and Stojanović, Zoran S. and Nikolić, Marko G. and Škapin, Srečo Davor and Jovanović, Sonja and Veselinović, Ljiljana and Uskoković, Vuk and Lazić, Snežana and Marković, Smilja and Lazarević, Miloš M. and Uskoković, Dragan",
year = "2019",
abstract = "Taking advantage of the flexibility of the apatite structure, nano- and micro-particles of hydroxyapatite (HAp) were doped with different combinations of rare earth ions (RE3+ = Gd, Eu, Yb, Tm) to achieve a synergy among their magnetic and optical properties and to enable their application in preventive medicine, particularly diagnostics based on multimodal imaging. All powders were synthesized through hydrothermal processing at T ≤ 200 °C. An X-ray powder diffraction analysis showed that all powders crystallized in P63/m space group of the hexagonal crystal structure. The refined unit-cell parameters reflected a decrease in the unit cell volume as a result of the partial substitution of Ca2+ with smaller RE3+ ions at both cation positions. The FTIR analysis additionally suggested that a synergy may exist solely in the triply doped system, where the lattice symmetry and vibration modes become more coherent than in the singly or doubly doped systems. HAp:RE3+ optical characterization revealed a change in the energy band gap and the appearance of a weak blue luminescence (λex = 370 nm) due to an increased concentration of defects. The “up”- and the “down”-conversion spectra of HAp:Gd/Yb/Tm and HAp:Gd/Eu powders showed characteristic transitions of Tm3+ and Eu3+, respectively. Furthermore, in contrast to diamagnetic HAp, all HAp:RE3+ powders exhibited paramagnetic behavior. Cell viability tests of HAp:Gd/Yb/Tm and HAp:Gd/Eu powders in human dental pulp stem cell cultures indicated their good biocompatibility.",
publisher = "Springer Nature",
journal = "Scientific Reports",
title = "Rare-earth (Gd 3+ ,Yb 3+ /Tm 3+ , Eu 3+ ) co-doped hydroxyapatite as magnetic, up-conversion and down-conversion materials for multimodal imaging",
pages = "1-15",
volume = "9",
number = "1",
doi = "10.1038/s41598-019-52885-0",
url = "https://hdl.handle.net/21.15107/rcub_dais_6950"
}
Ignjatović, N., Mančić, L., Vuković, M., Stojanović, Z. S., Nikolić, M. G., Škapin, S. D., Jovanović, S., Veselinović, L., Uskoković, V., Lazić, S., Marković, S., Lazarević, M. M.,& Uskoković, D.. (2019). Rare-earth (Gd 3+ ,Yb 3+ /Tm 3+ , Eu 3+ ) co-doped hydroxyapatite as magnetic, up-conversion and down-conversion materials for multimodal imaging. in Scientific Reports
Springer Nature., 9(1), 1-15.
https://doi.org/10.1038/s41598-019-52885-0
https://hdl.handle.net/21.15107/rcub_dais_6950
Ignjatović N, Mančić L, Vuković M, Stojanović ZS, Nikolić MG, Škapin SD, Jovanović S, Veselinović L, Uskoković V, Lazić S, Marković S, Lazarević MM, Uskoković D. Rare-earth (Gd 3+ ,Yb 3+ /Tm 3+ , Eu 3+ ) co-doped hydroxyapatite as magnetic, up-conversion and down-conversion materials for multimodal imaging. in Scientific Reports. 2019;9(1):1-15.
doi:10.1038/s41598-019-52885-0
https://hdl.handle.net/21.15107/rcub_dais_6950 .
Ignjatović, Nenad, Mančić, Lidija, Vuković, Marina, Stojanović, Zoran S., Nikolić, Marko G., Škapin, Srečo Davor, Jovanović, Sonja, Veselinović, Ljiljana, Uskoković, Vuk, Lazić, Snežana, Marković, Smilja, Lazarević, Miloš M., Uskoković, Dragan, "Rare-earth (Gd 3+ ,Yb 3+ /Tm 3+ , Eu 3+ ) co-doped hydroxyapatite as magnetic, up-conversion and down-conversion materials for multimodal imaging" in Scientific Reports, 9, no. 1 (2019):1-15,
https://doi.org/10.1038/s41598-019-52885-0 .,
https://hdl.handle.net/21.15107/rcub_dais_6950 .
1
29
20
30

Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents

Ignjatović, Nenad; Mančić, Lidija; Vuković, Marina; Stojanović, Zoran S.; Nikolić, Marko G.; Škapin, Srečo Davor; Jovanović, Sonja; Veselinović, Ljiljana; Lazić, Snežana; Marković, Smilja; Uskoković, Dragan

(Belgrade : Materials Research Society of Serbia, 2019)

TY  - CONF
AU  - Ignjatović, Nenad
AU  - Mančić, Lidija
AU  - Vuković, Marina
AU  - Stojanović, Zoran S.
AU  - Nikolić, Marko G.
AU  - Škapin, Srečo Davor
AU  - Jovanović, Sonja
AU  - Veselinović, Ljiljana
AU  - Lazić, Snežana
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6676
AB  - Hydroxyapatite (HAp) has been widely used as bone reconstruction materials due to their similarity to bone tissue. The improvement of HAp properties was achieved by doping its crystal lattice with different ions. Lanthanides, i.e. Rare Earth Elements (RE) are also suitable for doping HAp. The aim of the presented research was to investigate the possibility of creating lumino-magnetic particles of HAp doped with gadolinium (Gd3+) ions and co-doped with ytterbium/thulium (Yb3+/Tm3+) or europium (Eu3+) ions for potential use in multimodal imaging (MI). Pure HAp (Ca5(PO4)3(OH)), magnetic HAp:Gd (Ca4.85Gd0.15(PO4)3(OH)), and lumino-magnetic HAp:Gd/Yb/Tm (Ca4.85Gd0.03Yb0.1Tm0.02(PO4)3(OH)) and HAp:Gd/Eu (Ca4.94Gd0.02Eu0.04(PO4)3(OH)) particles were synthesized using emulsification process and hydrothermal processing. All synthesized particles had an elongated shape and exhibited a paramagnetic behavior. Reduction of the unit cell volume as a result of replacement of Ca2+ ions by ions with a smaller ionic radius (Gd3+, Yb3+, Tm3+, Eu3+) confirmed by using XRD and Rietveld refined plots. The energy band gap values of the synthesized samples range from 4.93 to 3.18 eV and decrease in the following order: HAp:Gd >HAp>HAp:Gd/Eu>HAp:Gd/Yb/Tm. The results of photoluminescence emission spectra of HAp:Gd/Yb/Tm and HAp:Gd/Eu particles showed characteristic transitions of Tm3+ and Eu3+, respectively.
PB  - Belgrade : Materials Research Society of Serbia
C3  - Programme and The Book of abstracts / Twenty-first Annual Conference YUCOMAT 2019 & Eleventh World Round Table Conference on Sintering WRTCS 2019, Herceg Novi, Montenegro, September 2-6, 2019
T1  - Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents
SP  - 76
EP  - 76
UR  - https://hdl.handle.net/21.15107/rcub_dais_6676
ER  - 
@conference{
author = "Ignjatović, Nenad and Mančić, Lidija and Vuković, Marina and Stojanović, Zoran S. and Nikolić, Marko G. and Škapin, Srečo Davor and Jovanović, Sonja and Veselinović, Ljiljana and Lazić, Snežana and Marković, Smilja and Uskoković, Dragan",
year = "2019",
abstract = "Hydroxyapatite (HAp) has been widely used as bone reconstruction materials due to their similarity to bone tissue. The improvement of HAp properties was achieved by doping its crystal lattice with different ions. Lanthanides, i.e. Rare Earth Elements (RE) are also suitable for doping HAp. The aim of the presented research was to investigate the possibility of creating lumino-magnetic particles of HAp doped with gadolinium (Gd3+) ions and co-doped with ytterbium/thulium (Yb3+/Tm3+) or europium (Eu3+) ions for potential use in multimodal imaging (MI). Pure HAp (Ca5(PO4)3(OH)), magnetic HAp:Gd (Ca4.85Gd0.15(PO4)3(OH)), and lumino-magnetic HAp:Gd/Yb/Tm (Ca4.85Gd0.03Yb0.1Tm0.02(PO4)3(OH)) and HAp:Gd/Eu (Ca4.94Gd0.02Eu0.04(PO4)3(OH)) particles were synthesized using emulsification process and hydrothermal processing. All synthesized particles had an elongated shape and exhibited a paramagnetic behavior. Reduction of the unit cell volume as a result of replacement of Ca2+ ions by ions with a smaller ionic radius (Gd3+, Yb3+, Tm3+, Eu3+) confirmed by using XRD and Rietveld refined plots. The energy band gap values of the synthesized samples range from 4.93 to 3.18 eV and decrease in the following order: HAp:Gd >HAp>HAp:Gd/Eu>HAp:Gd/Yb/Tm. The results of photoluminescence emission spectra of HAp:Gd/Yb/Tm and HAp:Gd/Eu particles showed characteristic transitions of Tm3+ and Eu3+, respectively.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "Programme and The Book of abstracts / Twenty-first Annual Conference YUCOMAT 2019 & Eleventh World Round Table Conference on Sintering WRTCS 2019, Herceg Novi, Montenegro, September 2-6, 2019",
title = "Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents",
pages = "76-76",
url = "https://hdl.handle.net/21.15107/rcub_dais_6676"
}
Ignjatović, N., Mančić, L., Vuković, M., Stojanović, Z. S., Nikolić, M. G., Škapin, S. D., Jovanović, S., Veselinović, L., Lazić, S., Marković, S.,& Uskoković, D.. (2019). Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents. in Programme and The Book of abstracts / Twenty-first Annual Conference YUCOMAT 2019 & Eleventh World Round Table Conference on Sintering WRTCS 2019, Herceg Novi, Montenegro, September 2-6, 2019
Belgrade : Materials Research Society of Serbia., 76-76.
https://hdl.handle.net/21.15107/rcub_dais_6676
Ignjatović N, Mančić L, Vuković M, Stojanović ZS, Nikolić MG, Škapin SD, Jovanović S, Veselinović L, Lazić S, Marković S, Uskoković D. Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents. in Programme and The Book of abstracts / Twenty-first Annual Conference YUCOMAT 2019 & Eleventh World Round Table Conference on Sintering WRTCS 2019, Herceg Novi, Montenegro, September 2-6, 2019. 2019;:76-76.
https://hdl.handle.net/21.15107/rcub_dais_6676 .
Ignjatović, Nenad, Mančić, Lidija, Vuković, Marina, Stojanović, Zoran S., Nikolić, Marko G., Škapin, Srečo Davor, Jovanović, Sonja, Veselinović, Ljiljana, Lazić, Snežana, Marković, Smilja, Uskoković, Dragan, "Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents" in Programme and The Book of abstracts / Twenty-first Annual Conference YUCOMAT 2019 & Eleventh World Round Table Conference on Sintering WRTCS 2019, Herceg Novi, Montenegro, September 2-6, 2019 (2019):76-76,
https://hdl.handle.net/21.15107/rcub_dais_6676 .

Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition

Pantović Pavlović, Marijana R.; Pavlović, Miroslav M.; Eraković, Sanja G.; Veselinović, Ljiljana; Stevanović, Jasmina S.; Panić, Vladimir V.; Ignjatović, Nenad

(Zvornik : Faculty of Technology, 2019)

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja G.
AU  - Veselinović, Ljiljana
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6226
AB  - In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.
PB  - Zvornik : Faculty of Technology
C3  - Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019
T1  - Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition
SP  - 630
EP  - 635
UR  - https://hdl.handle.net/21.15107/rcub_dais_6226
ER  - 
@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja G. and Veselinović, Ljiljana and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.",
publisher = "Zvornik : Faculty of Technology",
journal = "Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019",
title = "Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition",
pages = "630-635",
url = "https://hdl.handle.net/21.15107/rcub_dais_6226"
}
Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S. G., Veselinović, L., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition. in Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019
Zvornik : Faculty of Technology., 630-635.
https://hdl.handle.net/21.15107/rcub_dais_6226
Pantović Pavlović MR, Pavlović MM, Eraković SG, Veselinović L, Stevanović JS, Panić VV, Ignjatović N. Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition. in Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019. 2019;:630-635.
https://hdl.handle.net/21.15107/rcub_dais_6226 .
Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja G., Veselinović, Ljiljana, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition" in Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019 (2019):630-635,
https://hdl.handle.net/21.15107/rcub_dais_6226 .

Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis

Pantović Pavlović, Marijana R.; Eraković, Sanja G.; Pavlović, Miroslav M.; Veselinović, Ljiljana; Stevanović, Jasmina S.; Panić, Vladimir V.; Ignjatović, Nenad

(International Association of Physical Chemists, 2019)

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Eraković, Sanja G.
AU  - Pavlović, Miroslav M.
AU  - Veselinović, Ljiljana
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6244
AB  - The medical devices based on titanium and its alloys are widely used in the repair and replacement of a degraded or inhibited func-tion of locomotor system [1]. Ti and its alloys exhibit high mechanical strength, good workability, resistant to corrosion and low cost. Although, they are widely used as orthopedic and dental implants their inability to interact with living tissue will inhibit their biological fixation and osseoin-tegration [2]. Therefore, to improve the hard-tissue compatibility of Ti various sur-face treatments have been developed for the inorganic coating formation [3]. The hyd-roxyapatite (HAp, Ca10(PO4)6(OH)2) with superior osteogenic activity is a competitive approach to make novel coatings for titanium implants applications. HAp is a calcium phosphate very similar to the inorganic part of the human bone and hard tissues both in morphology and compo-sition. Herein, in-situ synthesis of HAp/TiO2 coating on titanium was performed via ana-phoretic deposition of HAp and simulta-neous anodization of Ti to produce highly adherent and strengthened composite coating. It can be seen that morphology of Ti substrate of anHAP/TiO2 coating is of tubular shape, and tube formation occurs mainly due to competing processes of anodization and electrophoretic deposition of HAp. anHAp/TiO2 coating does not need sintering process, and simultaneous Ti anodization and HAp deposition occur, where HAp crystals incorporate in the anodized Ti surface. From the presented results it can be concluded that novel suggested process of in situ simultaneous anHAp/TiO2 deposition with Ti surface anodization gives much better results that cathaphoretic deposition regarding adhesion.
PB  - International Association of Physical Chemists
C3  - Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
T1  - Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis
SP  - 120
EP  - 120
UR  - https://hdl.handle.net/21.15107/rcub_dais_6244
ER  - 
@conference{
author = "Pantović Pavlović, Marijana R. and Eraković, Sanja G. and Pavlović, Miroslav M. and Veselinović, Ljiljana and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "The medical devices based on titanium and its alloys are widely used in the repair and replacement of a degraded or inhibited func-tion of locomotor system [1]. Ti and its alloys exhibit high mechanical strength, good workability, resistant to corrosion and low cost. Although, they are widely used as orthopedic and dental implants their inability to interact with living tissue will inhibit their biological fixation and osseoin-tegration [2]. Therefore, to improve the hard-tissue compatibility of Ti various sur-face treatments have been developed for the inorganic coating formation [3]. The hyd-roxyapatite (HAp, Ca10(PO4)6(OH)2) with superior osteogenic activity is a competitive approach to make novel coatings for titanium implants applications. HAp is a calcium phosphate very similar to the inorganic part of the human bone and hard tissues both in morphology and compo-sition. Herein, in-situ synthesis of HAp/TiO2 coating on titanium was performed via ana-phoretic deposition of HAp and simulta-neous anodization of Ti to produce highly adherent and strengthened composite coating. It can be seen that morphology of Ti substrate of anHAP/TiO2 coating is of tubular shape, and tube formation occurs mainly due to competing processes of anodization and electrophoretic deposition of HAp. anHAp/TiO2 coating does not need sintering process, and simultaneous Ti anodization and HAp deposition occur, where HAp crystals incorporate in the anodized Ti surface. From the presented results it can be concluded that novel suggested process of in situ simultaneous anHAp/TiO2 deposition with Ti surface anodization gives much better results that cathaphoretic deposition regarding adhesion.",
publisher = "International Association of Physical Chemists",
journal = "Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019",
title = "Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis",
pages = "120-120",
url = "https://hdl.handle.net/21.15107/rcub_dais_6244"
}
Pantović Pavlović, M. R., Eraković, S. G., Pavlović, M. M., Veselinović, L., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
International Association of Physical Chemists., 120-120.
https://hdl.handle.net/21.15107/rcub_dais_6244
Pantović Pavlović MR, Eraković SG, Pavlović MM, Veselinović L, Stevanović JS, Panić VV, Ignjatović N. Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019. 2019;:120-120.
https://hdl.handle.net/21.15107/rcub_dais_6244 .
Pantović Pavlović, Marijana R., Eraković, Sanja G., Pavlović, Miroslav M., Veselinović, Ljiljana, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis" in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019 (2019):120-120,
https://hdl.handle.net/21.15107/rcub_dais_6244 .

Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion

Pantović Pavlović, Marijana R.; Pavlović, Miroslav M.; Eraković, Sanja G.; Stevanović, Jasmina S.; Ignjatović, Nenad; Panić, Vladimir V.

(Padova : Societa chimica italiana, Divisione di Elettrochimica, 2019)

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja G.
AU  - Stevanović, Jasmina S.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/7008
AB  - In-situ synthesis of hydroxyapatite/titanium oxide (HAp/TiO2) coating on titanium was performed via anaphoretic deposition of hydroxyapatite (HAp) and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and anodization of titanium was examined, as well as influence of same process parameters on adhesion strength and compactness of composite HAp/TiO2 coatings was investigated. Prior to novel in situ method of synthesis of hydroxyapatite/titanium oxide composite coatings by simultaneous anodization/anaphoretic electrodeposition described in this manuscript, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all anodization processes had constant quantity of electric charge. Characterization of titanium samples, prepared from grade 6 Ti, and having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness.
A chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of calcium oxide (obtained by calcination of CaCO3 for 5 h at 1000 °C in air) and phosphoric acid. A stoichiometric amount of the calcium oxide was stirred in distilled water and phosphoric acid was added drop wise to the suspension in order to obtain hydroxyapatite powder, Ca10(PO4)6(OH)2.
Two types of HAp coatings were prepared, in order to compare the adhesion, morphology and consistency of the HAp and composite HAp/TiO2 on Ti, namely cathaphoretic and anaphoretic coatings, respectively [1,2]. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. Adhesion was investigated by ASTM D 3359 – 97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to improved adhesion.
PB  - Padova : Societa chimica italiana, Divisione di Elettrochimica
C3  - Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy
T1  - Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion
SP  - 124
EP  - 124
UR  - https://hdl.handle.net/21.15107/rcub_dais_7008
ER  - 
@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja G. and Stevanović, Jasmina S. and Ignjatović, Nenad and Panić, Vladimir V.",
year = "2019",
abstract = "In-situ synthesis of hydroxyapatite/titanium oxide (HAp/TiO2) coating on titanium was performed via anaphoretic deposition of hydroxyapatite (HAp) and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and anodization of titanium was examined, as well as influence of same process parameters on adhesion strength and compactness of composite HAp/TiO2 coatings was investigated. Prior to novel in situ method of synthesis of hydroxyapatite/titanium oxide composite coatings by simultaneous anodization/anaphoretic electrodeposition described in this manuscript, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all anodization processes had constant quantity of electric charge. Characterization of titanium samples, prepared from grade 6 Ti, and having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness.
A chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of calcium oxide (obtained by calcination of CaCO3 for 5 h at 1000 °C in air) and phosphoric acid. A stoichiometric amount of the calcium oxide was stirred in distilled water and phosphoric acid was added drop wise to the suspension in order to obtain hydroxyapatite powder, Ca10(PO4)6(OH)2.
Two types of HAp coatings were prepared, in order to compare the adhesion, morphology and consistency of the HAp and composite HAp/TiO2 on Ti, namely cathaphoretic and anaphoretic coatings, respectively [1,2]. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. Adhesion was investigated by ASTM D 3359 – 97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to improved adhesion.",
publisher = "Padova : Societa chimica italiana, Divisione di Elettrochimica",
journal = "Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy",
title = "Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion",
pages = "124-124",
url = "https://hdl.handle.net/21.15107/rcub_dais_7008"
}
Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S. G., Stevanović, J. S., Ignjatović, N.,& Panić, V. V.. (2019). Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion. in Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy
Padova : Societa chimica italiana, Divisione di Elettrochimica., 124-124.
https://hdl.handle.net/21.15107/rcub_dais_7008
Pantović Pavlović MR, Pavlović MM, Eraković SG, Stevanović JS, Ignjatović N, Panić VV. Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion. in Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy. 2019;:124-124.
https://hdl.handle.net/21.15107/rcub_dais_7008 .
Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja G., Stevanović, Jasmina S., Ignjatović, Nenad, Panić, Vladimir V., "Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion" in Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy (2019):124-124,
https://hdl.handle.net/21.15107/rcub_dais_7008 .

In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition

Pantović Pavlović, Marijana R.; Pavlović, Miroslav M.; Eraković, Sanja G.; Barudžija, Tanja; Stevanović, Jasmina S.; Ignjatović, Nenad; Panić, Vladimir V.

(Novi Sad : Faculty of Technology, 2019)

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja G.
AU  - Barudžija, Tanja
AU  - Stevanović, Jasmina S.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6983
AB  - Titanium substrates were electrochemically treated by novel in-situ synthesis method to produce anaphoretic hydroxyapatite/titanium oxide (HAp/TiO2) coating. This synthesis method was performed via anaphoretic deposition of hydroxyapatite and simultaneous anodization of Ti in order to produce highly adherent and strengthened composite coating, where the influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and adhesion strength of composite HAp/TiO2 coatings was examined. In situ synthesis was performed in different solutions containing different concentrations of NaOH, HAp and ethanol at different values of time and constant voltage. The effects of anodizing voltage on the morphology and bioactivity of the HAp coating and on the bonding strength between the HAp coating and the anodized substrates were investigated. A modified chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of stoichiometric amount of calcium oxide and phosphoric acid. Prior to novel in situ synthesis of HAp/TiO2 composite coatings, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all experiments had constant quantity of electric charge. Results indicated that highly ordered amorphous TiO2 surface is formed on the Ti substrate after anodic oxidation. Characterization of titanium samples having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness. The prepared coatings were characterized by FE-SEM, XRD and EDS. Adhesion was investigated by ASTM D 3359–97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. The results of simulated body fluid immersing experiments suggest that obtained HAp coating exhibits promising bioactivity. The obtained coating can be good candidate for bone implants due to improved adhesion.
PB  - Novi Sad : Faculty of Technology
C3  - Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad
T1  - In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition
SP  - 131
EP  - 131
UR  - https://hdl.handle.net/21.15107/rcub_dais_6983
ER  - 
@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja G. and Barudžija, Tanja and Stevanović, Jasmina S. and Ignjatović, Nenad and Panić, Vladimir V.",
year = "2019",
abstract = "Titanium substrates were electrochemically treated by novel in-situ synthesis method to produce anaphoretic hydroxyapatite/titanium oxide (HAp/TiO2) coating. This synthesis method was performed via anaphoretic deposition of hydroxyapatite and simultaneous anodization of Ti in order to produce highly adherent and strengthened composite coating, where the influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and adhesion strength of composite HAp/TiO2 coatings was examined. In situ synthesis was performed in different solutions containing different concentrations of NaOH, HAp and ethanol at different values of time and constant voltage. The effects of anodizing voltage on the morphology and bioactivity of the HAp coating and on the bonding strength between the HAp coating and the anodized substrates were investigated. A modified chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of stoichiometric amount of calcium oxide and phosphoric acid. Prior to novel in situ synthesis of HAp/TiO2 composite coatings, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all experiments had constant quantity of electric charge. Results indicated that highly ordered amorphous TiO2 surface is formed on the Ti substrate after anodic oxidation. Characterization of titanium samples having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness. The prepared coatings were characterized by FE-SEM, XRD and EDS. Adhesion was investigated by ASTM D 3359–97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. The results of simulated body fluid immersing experiments suggest that obtained HAp coating exhibits promising bioactivity. The obtained coating can be good candidate for bone implants due to improved adhesion.",
publisher = "Novi Sad : Faculty of Technology",
journal = "Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad",
title = "In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition",
pages = "131-131",
url = "https://hdl.handle.net/21.15107/rcub_dais_6983"
}
Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S. G., Barudžija, T., Stevanović, J. S., Ignjatović, N.,& Panić, V. V.. (2019). In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition. in Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad
Novi Sad : Faculty of Technology., 131-131.
https://hdl.handle.net/21.15107/rcub_dais_6983
Pantović Pavlović MR, Pavlović MM, Eraković SG, Barudžija T, Stevanović JS, Ignjatović N, Panić VV. In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition. in Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad. 2019;:131-131.
https://hdl.handle.net/21.15107/rcub_dais_6983 .
Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja G., Barudžija, Tanja, Stevanović, Jasmina S., Ignjatović, Nenad, Panić, Vladimir V., "In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition" in Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad (2019):131-131,
https://hdl.handle.net/21.15107/rcub_dais_6983 .

Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite

Pantović Pavlović, Marijana R.; Pavlović, Miroslav M.; Eraković, Sanja; Barudžija, Tanja; Stevanović, Jasmina S.; Ignjatović, Nenad; Panić, Vladimir V.

(Serbian Chemical Society, 2019)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja
AU  - Barudžija, Tanja
AU  - Stevanović, Jasmina S.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
PY  - 2019
UR  - https://www.shd-pub.org.rs/index.php/JSCS/article/view/8524
UR  - https://dais.sanu.ac.rs/123456789/6916
AB  - The optimization of the anodization process of Ti substrate for in situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium substrate was accomplished. The anodization was performed under 30, 60 and 90 V cell voltage, and the morphology of treated surface, as well as linear and surface roughness, were analysed by field emission-scanning electron micro­scopy, atomic force microscopy and roughness tester. It was shown by linear and surface roughness analyses that titanium anodized under 60 V has the high­est roughness, whereas at 90 V the flattening of the surface occurs. As the highest surface roughness results emerged at 60 V, the novel process of com­po­site anHAp/TiO2 coating synthesis, which comprises simultaneous processes of TiO2 formation and HAp deposition, as well as HAp impregnation within TiO2 surface layer, was performed at this voltage. Ti substrate surface was completely covered by composite coating, with no visible cracks. The adhesion quantified according to ASTM D3359-02 standard is considerably improved with respect to the coatings obtained by cathaphoretic processes, with no need of subsequent sintering.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite
SP  - 1305
EP  - 1318
VL  - 84
IS  - 11
DO  - 10.2298/JSC190730105P
UR  - https://hdl.handle.net/21.15107/rcub_dais_6916
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja and Barudžija, Tanja and Stevanović, Jasmina S. and Ignjatović, Nenad and Panić, Vladimir V.",
year = "2019",
abstract = "The optimization of the anodization process of Ti substrate for in situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium substrate was accomplished. The anodization was performed under 30, 60 and 90 V cell voltage, and the morphology of treated surface, as well as linear and surface roughness, were analysed by field emission-scanning electron micro­scopy, atomic force microscopy and roughness tester. It was shown by linear and surface roughness analyses that titanium anodized under 60 V has the high­est roughness, whereas at 90 V the flattening of the surface occurs. As the highest surface roughness results emerged at 60 V, the novel process of com­po­site anHAp/TiO2 coating synthesis, which comprises simultaneous processes of TiO2 formation and HAp deposition, as well as HAp impregnation within TiO2 surface layer, was performed at this voltage. Ti substrate surface was completely covered by composite coating, with no visible cracks. The adhesion quantified according to ASTM D3359-02 standard is considerably improved with respect to the coatings obtained by cathaphoretic processes, with no need of subsequent sintering.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite",
pages = "1305-1318",
volume = "84",
number = "11",
doi = "10.2298/JSC190730105P",
url = "https://hdl.handle.net/21.15107/rcub_dais_6916"
}
Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S., Barudžija, T., Stevanović, J. S., Ignjatović, N.,& Panić, V. V.. (2019). Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 84(11), 1305-1318.
https://doi.org/10.2298/JSC190730105P
https://hdl.handle.net/21.15107/rcub_dais_6916
Pantović Pavlović MR, Pavlović MM, Eraković S, Barudžija T, Stevanović JS, Ignjatović N, Panić VV. Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite. in Journal of the Serbian Chemical Society. 2019;84(11):1305-1318.
doi:10.2298/JSC190730105P
https://hdl.handle.net/21.15107/rcub_dais_6916 .
Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja, Barudžija, Tanja, Stevanović, Jasmina S., Ignjatović, Nenad, Panić, Vladimir V., "Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite" in Journal of the Serbian Chemical Society, 84, no. 11 (2019):1305-1318,
https://doi.org/10.2298/JSC190730105P .,
https://hdl.handle.net/21.15107/rcub_dais_6916 .
2
1
3

Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium

Pantović Pavlović, Marijana R.; Eraković, Sanja G.; Pavlović, Miroslav M.; Stevanović, Jasmina S.; Panić, Vladimir V.; Ignjatović, Nenad

(Elsevier, 2019)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Eraković, Sanja G.
AU  - Pavlović, Miroslav M.
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - http://www.sciencedirect.com/science/article/pii/S0257897218313148
UR  - https://dais.sanu.ac.rs/123456789/4556
AB  - In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.
PB  - Elsevier
T2  - Surface and Coatings Technology
T1  - Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium
SP  - 688
EP  - 694
VL  - 358
DO  - 10.1016/j.surfcoat.2018.12.003
UR  - https://hdl.handle.net/21.15107/rcub_dais_4556
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Eraković, Sanja G. and Pavlović, Miroslav M. and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.",
publisher = "Elsevier",
journal = "Surface and Coatings Technology",
title = "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium",
pages = "688-694",
volume = "358",
doi = "10.1016/j.surfcoat.2018.12.003",
url = "https://hdl.handle.net/21.15107/rcub_dais_4556"
}
Pantović Pavlović, M. R., Eraković, S. G., Pavlović, M. M., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology
Elsevier., 358, 688-694.
https://doi.org/10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4556
Pantović Pavlović MR, Eraković SG, Pavlović MM, Stevanović JS, Panić VV, Ignjatović N. Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology. 2019;358:688-694.
doi:10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4556 .
Pantović Pavlović, Marijana R., Eraković, Sanja G., Pavlović, Miroslav M., Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium" in Surface and Coatings Technology, 358 (2019):688-694,
https://doi.org/10.1016/j.surfcoat.2018.12.003 .,
https://hdl.handle.net/21.15107/rcub_dais_4556 .
6
8
9

Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium

Pantović Pavlović, Marijana R.; Eraković, Sanja G.; Pavlović, Miroslav M.; Stevanović, Jasmina S.; Panić, Vladimir V.; Ignjatović, Nenad

(Elsevier, 2019)

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Eraković, Sanja G.
AU  - Pavlović, Miroslav M.
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - http://www.sciencedirect.com/science/article/pii/S0257897218313148
UR  - https://dais.sanu.ac.rs/123456789/4555
AB  - In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.
PB  - Elsevier
T2  - Surface and Coatings Technology
T2  - Surface and Coatings TechnologySurface and Coatings Technology
T1  - Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium
SP  - 688
EP  - 694
VL  - 358
DO  - 10.1016/j.surfcoat.2018.12.003
UR  - https://hdl.handle.net/21.15107/rcub_dais_4555
ER  - 
@article{
author = "Pantović Pavlović, Marijana R. and Eraković, Sanja G. and Pavlović, Miroslav M. and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.",
publisher = "Elsevier",
journal = "Surface and Coatings Technology, Surface and Coatings TechnologySurface and Coatings Technology",
title = "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium",
pages = "688-694",
volume = "358",
doi = "10.1016/j.surfcoat.2018.12.003",
url = "https://hdl.handle.net/21.15107/rcub_dais_4555"
}
Pantović Pavlović, M. R., Eraković, S. G., Pavlović, M. M., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology
Elsevier., 358, 688-694.
https://doi.org/10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4555
Pantović Pavlović MR, Eraković SG, Pavlović MM, Stevanović JS, Panić VV, Ignjatović N. Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology. 2019;358:688-694.
doi:10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4555 .
Pantović Pavlović, Marijana R., Eraković, Sanja G., Pavlović, Miroslav M., Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium" in Surface and Coatings Technology, 358 (2019):688-694,
https://doi.org/10.1016/j.surfcoat.2018.12.003 .,
https://hdl.handle.net/21.15107/rcub_dais_4555 .
6
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Effects of Hydroxyapatite@Poly-Lactide-Co-Glycolide Nanoparticles Combined with Pb and Cd on Liver and Kidney Parenchyma after the Reconstruction of Mandibular Bone Defects

Ignjatović, Nenad; Janković, Radmila; Uskoković, Vuk; Uskoković, Dragan

(2019)

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Janković, Radmila
AU  - Uskoković, Vuk
AU  - Uskoković, Dragan
PY  - 2019
UR  - https://pubs.rsc.org/en/content/articlelanding/2019/tx/c9tx00007k
UR  - https://dais.sanu.ac.rs/123456789/4961
AB  - Reconstruction of bone defects with the use of biomaterials based on hydroxyapatite (HAp) has been a popular approach in medicine and dentistry. Most often the process of new bone formation is analyzed with the focus only on the region of the reconstructed defect. The effects of the therapy on distant organs have been rarely reported in literature, especially not in synergy with the exposure to other bioactive chemicals. In this study, reconstruction of the mandibular bone in vivo using poly-lactide-co-glycolide-coated HAp (HAp/PLGA) nanoparticles was monitored with a simultaneous histopathological analysis of distant organs, specifically kidney and liver parenchyma. Heavy metals are among the most prominent environmental pollutants and have a high affinity for the crystal lattice of HAp, where they get incorporated by replacing calcium ions. Lead (Pb) and cadmium (Cd) are two such metals that can be found in food, water and air, but are most commonly present in cigarette smoke, the frequent contaminant of hospital settings in the developing world. A study performed on 24 female Wistar rats demonstrated that the reconstruction of mandibular bone defects using HAp/PLGA particles induced an increase in the content of Ca in the newly created bone without causing any pathological changes to the liver and the kidneys. The presence of Pb and Cd in the defects reconstructed with HAp/PLGA nanoparticles impeded the regenerative process and led to a severe and irreversible damage to the liver and kidney parenchyma.
T2  - Toxicology Research
T1  - Effects of Hydroxyapatite@Poly-Lactide-Co-Glycolide Nanoparticles Combined with Pb and Cd on Liver and Kidney Parenchyma after the Reconstruction of Mandibular Bone Defects
SP  - 287
EP  - 296
VL  - 8
DO  - 10.1039/C9TX00007K
UR  - https://hdl.handle.net/21.15107/rcub_dais_4961
ER  - 
@article{
author = "Ignjatović, Nenad and Janković, Radmila and Uskoković, Vuk and Uskoković, Dragan",
year = "2019",
abstract = "Reconstruction of bone defects with the use of biomaterials based on hydroxyapatite (HAp) has been a popular approach in medicine and dentistry. Most often the process of new bone formation is analyzed with the focus only on the region of the reconstructed defect. The effects of the therapy on distant organs have been rarely reported in literature, especially not in synergy with the exposure to other bioactive chemicals. In this study, reconstruction of the mandibular bone in vivo using poly-lactide-co-glycolide-coated HAp (HAp/PLGA) nanoparticles was monitored with a simultaneous histopathological analysis of distant organs, specifically kidney and liver parenchyma. Heavy metals are among the most prominent environmental pollutants and have a high affinity for the crystal lattice of HAp, where they get incorporated by replacing calcium ions. Lead (Pb) and cadmium (Cd) are two such metals that can be found in food, water and air, but are most commonly present in cigarette smoke, the frequent contaminant of hospital settings in the developing world. A study performed on 24 female Wistar rats demonstrated that the reconstruction of mandibular bone defects using HAp/PLGA particles induced an increase in the content of Ca in the newly created bone without causing any pathological changes to the liver and the kidneys. The presence of Pb and Cd in the defects reconstructed with HAp/PLGA nanoparticles impeded the regenerative process and led to a severe and irreversible damage to the liver and kidney parenchyma.",
journal = "Toxicology Research",
title = "Effects of Hydroxyapatite@Poly-Lactide-Co-Glycolide Nanoparticles Combined with Pb and Cd on Liver and Kidney Parenchyma after the Reconstruction of Mandibular Bone Defects",
pages = "287-296",
volume = "8",
doi = "10.1039/C9TX00007K",
url = "https://hdl.handle.net/21.15107/rcub_dais_4961"
}
Ignjatović, N., Janković, R., Uskoković, V.,& Uskoković, D.. (2019). Effects of Hydroxyapatite@Poly-Lactide-Co-Glycolide Nanoparticles Combined with Pb and Cd on Liver and Kidney Parenchyma after the Reconstruction of Mandibular Bone Defects. in Toxicology Research, 8, 287-296.
https://doi.org/10.1039/C9TX00007K
https://hdl.handle.net/21.15107/rcub_dais_4961
Ignjatović N, Janković R, Uskoković V, Uskoković D. Effects of Hydroxyapatite@Poly-Lactide-Co-Glycolide Nanoparticles Combined with Pb and Cd on Liver and Kidney Parenchyma after the Reconstruction of Mandibular Bone Defects. in Toxicology Research. 2019;8:287-296.
doi:10.1039/C9TX00007K
https://hdl.handle.net/21.15107/rcub_dais_4961 .
Ignjatović, Nenad, Janković, Radmila, Uskoković, Vuk, Uskoković, Dragan, "Effects of Hydroxyapatite@Poly-Lactide-Co-Glycolide Nanoparticles Combined with Pb and Cd on Liver and Kidney Parenchyma after the Reconstruction of Mandibular Bone Defects" in Toxicology Research, 8 (2019):287-296,
https://doi.org/10.1039/C9TX00007K .,
https://hdl.handle.net/21.15107/rcub_dais_4961 .
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