Petković, Marijana

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orcid::0000-0002-8354-995X
  • Petković, Marijana (7)
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Author's Bibliography

Structure analysis of geopolymers synthesized from clay originated from Serbia

Nenadović, Snežana S.; Kljajević, Ljiljana M.; Nešić, Maja A.; Petković, Marijana; Trivunac, Katarina V.; Pavlović, Vladimir B.

(Springer, 2017)

TY  - JOUR
AU  - Nenadović, Snežana S.
AU  - Kljajević, Ljiljana M.
AU  - Nešić, Maja A.
AU  - Petković, Marijana
AU  - Trivunac, Katarina V.
AU  - Pavlović, Vladimir B.
PY  - 2017
UR  - https://dais.sanu.ac.rs/123456789/2348
AB  - The paper presents chemical and structural analysis of geopolymer materials which are obtained by alkali-activated calcined clay (metakaolin) originated from Serbia under strictly defined conditions. Characterization of the metakaolin and geopolymers molecular structure has been done using X-ray diffraction, scanning electron microscope, Fourier transform infrared spectroscopy and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The paper presents the possibility of obtaining geopolymer structure and differences in chemical and structural characterization of these materials taking into account the concentration of NaOH as a variable parameter. The results of MALDI analysis of metakaolin and synthesized geopolymer structures using various matrix system: 2,4,6 trihydroxyacetophenone (THAP), α-cyano-4-hydroxycinnamic, 2,6 dihydroxyacetophenone and laser desorption/ionization, have shown that THAP matrix is the most appropriate for analysing these aluminosilicate materials.
PB  - Springer
T2  - Environmental Earth Sciences
T1  - Structure analysis of geopolymers synthesized from clay originated from Serbia
SP  - 76
VL  - 79
DO  - 10.1007/s12665-016-6360-4
UR  - https://hdl.handle.net/21.15107/rcub_dais_2348
ER  - 
@article{
author = "Nenadović, Snežana S. and Kljajević, Ljiljana M. and Nešić, Maja A. and Petković, Marijana and Trivunac, Katarina V. and Pavlović, Vladimir B.",
year = "2017",
abstract = "The paper presents chemical and structural analysis of geopolymer materials which are obtained by alkali-activated calcined clay (metakaolin) originated from Serbia under strictly defined conditions. Characterization of the metakaolin and geopolymers molecular structure has been done using X-ray diffraction, scanning electron microscope, Fourier transform infrared spectroscopy and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The paper presents the possibility of obtaining geopolymer structure and differences in chemical and structural characterization of these materials taking into account the concentration of NaOH as a variable parameter. The results of MALDI analysis of metakaolin and synthesized geopolymer structures using various matrix system: 2,4,6 trihydroxyacetophenone (THAP), α-cyano-4-hydroxycinnamic, 2,6 dihydroxyacetophenone and laser desorption/ionization, have shown that THAP matrix is the most appropriate for analysing these aluminosilicate materials.",
publisher = "Springer",
journal = "Environmental Earth Sciences",
title = "Structure analysis of geopolymers synthesized from clay originated from Serbia",
pages = "76",
volume = "79",
doi = "10.1007/s12665-016-6360-4",
url = "https://hdl.handle.net/21.15107/rcub_dais_2348"
}
Nenadović, S. S., Kljajević, L. M., Nešić, M. A., Petković, M., Trivunac, K. V.,& Pavlović, V. B.. (2017). Structure analysis of geopolymers synthesized from clay originated from Serbia. in Environmental Earth Sciences
Springer., 79, 76.
https://doi.org/10.1007/s12665-016-6360-4
https://hdl.handle.net/21.15107/rcub_dais_2348
Nenadović SS, Kljajević LM, Nešić MA, Petković M, Trivunac KV, Pavlović VB. Structure analysis of geopolymers synthesized from clay originated from Serbia. in Environmental Earth Sciences. 2017;79:76.
doi:10.1007/s12665-016-6360-4
https://hdl.handle.net/21.15107/rcub_dais_2348 .
Nenadović, Snežana S., Kljajević, Ljiljana M., Nešić, Maja A., Petković, Marijana, Trivunac, Katarina V., Pavlović, Vladimir B., "Structure analysis of geopolymers synthesized from clay originated from Serbia" in Environmental Earth Sciences, 79 (2017):76,
https://doi.org/10.1007/s12665-016-6360-4 .,
https://hdl.handle.net/21.15107/rcub_dais_2348 .
1
21
14
25

Preparation of smallest microparticles of poly-D,L-lactide by modified precipitation method: Influence of the process parameters

Jovanović, Ivana; Jordović, Branka; Petković, Marijana; Ignjatović, Nenad; Uskoković, Dragan

(Hoboken, NJ : John Wiley & Sons, 2008)

TY  - JOUR
AU  - Jovanović, Ivana
AU  - Jordović, Branka
AU  - Petković, Marijana
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2008
UR  - https://dais.sanu.ac.rs/123456789/177
AB  - Biodegradable microspheres such as those made of poly-D,L-lactide (PDLLA) are widely investigated delivery systems for drugs or antigens. The aim of this study was to examine experimental conditions in order to produce PDLLA microspheres with the best properties for controlled and sustained drug delivery by the modified precipitation method. For this purpose, the following parameters were varied: co-solvent (methanol or ethanol), the concentration of stabilizer polyvinyl alcohol (PVA), chloroform-to-water ratio and the speed and time of homogenization. Scanning electron microscopy (SEM) and stereological analysis were used to characterize the particles. The average size and morphology of the microspheres varied substantially with preparation conditions from 8.44–1.25 μm. Results showed that the smallest particles were obtained with methanol, 1% PVA and with 10 min of homogenization at 21,000 rpm. Microsc. Res. Tech., 2008. © 2007 Wiley-Liss, Inc.
PB  - Hoboken, NJ : John Wiley & Sons
T2  - Microscopy Research and Technique
T1  - Preparation of smallest microparticles of poly-D,L-lactide by modified precipitation method: Influence of the process parameters
SP  - 86
EP  - 92
VL  - 72
IS  - 2
DO  - 10.1002/jemt.20529
UR  - https://hdl.handle.net/21.15107/rcub_dais_177
ER  - 
@article{
author = "Jovanović, Ivana and Jordović, Branka and Petković, Marijana and Ignjatović, Nenad and Uskoković, Dragan",
year = "2008",
abstract = "Biodegradable microspheres such as those made of poly-D,L-lactide (PDLLA) are widely investigated delivery systems for drugs or antigens. The aim of this study was to examine experimental conditions in order to produce PDLLA microspheres with the best properties for controlled and sustained drug delivery by the modified precipitation method. For this purpose, the following parameters were varied: co-solvent (methanol or ethanol), the concentration of stabilizer polyvinyl alcohol (PVA), chloroform-to-water ratio and the speed and time of homogenization. Scanning electron microscopy (SEM) and stereological analysis were used to characterize the particles. The average size and morphology of the microspheres varied substantially with preparation conditions from 8.44–1.25 μm. Results showed that the smallest particles were obtained with methanol, 1% PVA and with 10 min of homogenization at 21,000 rpm. Microsc. Res. Tech., 2008. © 2007 Wiley-Liss, Inc.",
publisher = "Hoboken, NJ : John Wiley & Sons",
journal = "Microscopy Research and Technique",
title = "Preparation of smallest microparticles of poly-D,L-lactide by modified precipitation method: Influence of the process parameters",
pages = "86-92",
volume = "72",
number = "2",
doi = "10.1002/jemt.20529",
url = "https://hdl.handle.net/21.15107/rcub_dais_177"
}
Jovanović, I., Jordović, B., Petković, M., Ignjatović, N.,& Uskoković, D.. (2008). Preparation of smallest microparticles of poly-D,L-lactide by modified precipitation method: Influence of the process parameters. in Microscopy Research and Technique
Hoboken, NJ : John Wiley & Sons., 72(2), 86-92.
https://doi.org/10.1002/jemt.20529
https://hdl.handle.net/21.15107/rcub_dais_177
Jovanović I, Jordović B, Petković M, Ignjatović N, Uskoković D. Preparation of smallest microparticles of poly-D,L-lactide by modified precipitation method: Influence of the process parameters. in Microscopy Research and Technique. 2008;72(2):86-92.
doi:10.1002/jemt.20529
https://hdl.handle.net/21.15107/rcub_dais_177 .
Jovanović, Ivana, Jordović, Branka, Petković, Marijana, Ignjatović, Nenad, Uskoković, Dragan, "Preparation of smallest microparticles of poly-D,L-lactide by modified precipitation method: Influence of the process parameters" in Microscopy Research and Technique, 72, no. 2 (2008):86-92,
https://doi.org/10.1002/jemt.20529 .,
https://hdl.handle.net/21.15107/rcub_dais_177 .
8
9
12

Ultrasound synthesis of poly-dl-lactide-co-glycolide/hydroxyapatite core-shell nano-spheres

Uskoković, Dragan; Jevtić, Marija; Petković, Marijana; Ignjatović, Nenad; Mitrić, Miodrag

(2008)

TY  - CONF
AU  - Uskoković, Dragan
AU  - Jevtić, Marija
AU  - Petković, Marijana
AU  - Ignjatović, Nenad
AU  - Mitrić, Miodrag
PY  - 2008
UR  - https://dais.sanu.ac.rs/123456789/3566
C3  - 8th World Biomaterials Congress 2008, WBC 2008; Amsterdam; Netherlands; 28 May 2008 - 1 June 2008
T1  - Ultrasound synthesis of poly-dl-lactide-co-glycolide/hydroxyapatite core-shell nano-spheres
SP  - 1029
EP  - 1029
VL  - Vol. 2
UR  - https://hdl.handle.net/21.15107/rcub_dais_3566
ER  - 
@conference{
author = "Uskoković, Dragan and Jevtić, Marija and Petković, Marijana and Ignjatović, Nenad and Mitrić, Miodrag",
year = "2008",
journal = "8th World Biomaterials Congress 2008, WBC 2008; Amsterdam; Netherlands; 28 May 2008 - 1 June 2008",
title = "Ultrasound synthesis of poly-dl-lactide-co-glycolide/hydroxyapatite core-shell nano-spheres",
pages = "1029-1029",
volume = "Vol. 2",
url = "https://hdl.handle.net/21.15107/rcub_dais_3566"
}
Uskoković, D., Jevtić, M., Petković, M., Ignjatović, N.,& Mitrić, M.. (2008). Ultrasound synthesis of poly-dl-lactide-co-glycolide/hydroxyapatite core-shell nano-spheres. in 8th World Biomaterials Congress 2008, WBC 2008; Amsterdam; Netherlands; 28 May 2008 - 1 June 2008, Vol. 2, 1029-1029.
https://hdl.handle.net/21.15107/rcub_dais_3566
Uskoković D, Jevtić M, Petković M, Ignjatović N, Mitrić M. Ultrasound synthesis of poly-dl-lactide-co-glycolide/hydroxyapatite core-shell nano-spheres. in 8th World Biomaterials Congress 2008, WBC 2008; Amsterdam; Netherlands; 28 May 2008 - 1 June 2008. 2008;Vol. 2:1029-1029.
https://hdl.handle.net/21.15107/rcub_dais_3566 .
Uskoković, Dragan, Jevtić, Marija, Petković, Marijana, Ignjatović, Nenad, Mitrić, Miodrag, "Ultrasound synthesis of poly-dl-lactide-co-glycolide/hydroxyapatite core-shell nano-spheres" in 8th World Biomaterials Congress 2008, WBC 2008; Amsterdam; Netherlands; 28 May 2008 - 1 June 2008, Vol. 2 (2008):1029-1029,
https://hdl.handle.net/21.15107/rcub_dais_3566 .

PDLLA microparticles containing BSA: effect of formulation variables on size distribution

Jovanović, Ivana; Petković, Marijana; Jordović, Branka; Ignjatović, Nenad; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2007)

TY  - CONF
AU  - Jovanović, Ivana
AU  - Petković, Marijana
AU  - Jordović, Branka
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2007
UR  - https://dais.sanu.ac.rs/123456789/6282
AB  - Worldwide, there is u currently considerable care for the development of
biodegradable microspheres as systems for controlled release of medicaments. The major
disadvantage of traditional administration routes of medicaments is the need for frequent
repetition. Encapsulation has been proven to be an effective vehicle for the controlled delivery
of various medicaments. The encapsulation efficiency and release kinetics of the medicaments
have been found to be dependent upon the size of the microspheres synthesized. The aim of this
study was to formulate microparticles from poly-dl-lactide (PDLLA) by modified precipitation
method. Bovine serum albumin (BSA) was used as a model protein for encapsulation. The
surfactant polyvinyl alcohol (PVA) was incorporated to increase encapsulation efficiency and to
achieve PDLLA spheres with desired size. The main focus was to study the effect of co-solvent
selection (methanol or ethanol), PVA concentration, chloroform-to-water ratio, the speed and
time of homogenization and solvent removal rate on the properties of microparticles. The
average size and morphology of microparticles varied substantially among these preparation
conditions. An increase in stirring rate and time of homogenization and concentration of
stabilizer agent were found to reduce moderately the size of microparticles. Other process
parameters had limited influence on particle size.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
T1  - PDLLA microparticles containing BSA: effect of formulation variables on size distribution
SP  - 170
EP  - 170
UR  - https://hdl.handle.net/21.15107/rcub_dais_6282
ER  - 
@conference{
author = "Jovanović, Ivana and Petković, Marijana and Jordović, Branka and Ignjatović, Nenad and Uskoković, Dragan",
year = "2007",
abstract = "Worldwide, there is u currently considerable care for the development of
biodegradable microspheres as systems for controlled release of medicaments. The major
disadvantage of traditional administration routes of medicaments is the need for frequent
repetition. Encapsulation has been proven to be an effective vehicle for the controlled delivery
of various medicaments. The encapsulation efficiency and release kinetics of the medicaments
have been found to be dependent upon the size of the microspheres synthesized. The aim of this
study was to formulate microparticles from poly-dl-lactide (PDLLA) by modified precipitation
method. Bovine serum albumin (BSA) was used as a model protein for encapsulation. The
surfactant polyvinyl alcohol (PVA) was incorporated to increase encapsulation efficiency and to
achieve PDLLA spheres with desired size. The main focus was to study the effect of co-solvent
selection (methanol or ethanol), PVA concentration, chloroform-to-water ratio, the speed and
time of homogenization and solvent removal rate on the properties of microparticles. The
average size and morphology of microparticles varied substantially among these preparation
conditions. An increase in stirring rate and time of homogenization and concentration of
stabilizer agent were found to reduce moderately the size of microparticles. Other process
parameters had limited influence on particle size.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007",
title = "PDLLA microparticles containing BSA: effect of formulation variables on size distribution",
pages = "170-170",
url = "https://hdl.handle.net/21.15107/rcub_dais_6282"
}
Jovanović, I., Petković, M., Jordović, B., Ignjatović, N.,& Uskoković, D.. (2007). PDLLA microparticles containing BSA: effect of formulation variables on size distribution. in Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
Belgrade : Institute of Technical Sciences of SASA., 170-170.
https://hdl.handle.net/21.15107/rcub_dais_6282
Jovanović I, Petković M, Jordović B, Ignjatović N, Uskoković D. PDLLA microparticles containing BSA: effect of formulation variables on size distribution. in Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007. 2007;:170-170.
https://hdl.handle.net/21.15107/rcub_dais_6282 .
Jovanović, Ivana, Petković, Marijana, Jordović, Branka, Ignjatović, Nenad, Uskoković, Dragan, "PDLLA microparticles containing BSA: effect of formulation variables on size distribution" in Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007 (2007):170-170,
https://hdl.handle.net/21.15107/rcub_dais_6282 .

Genotoxicity of the poly-D,L-lactide microparticles on the human lymphocytes

Jovanović, Ivana; Petković, Marijana; Joksić, Gordana; Uskoković, Dragan

(Belgrade : Institute of Technical Sciences of SASA, 2007)

TY  - CONF
AU  - Jovanović, Ivana
AU  - Petković, Marijana
AU  - Joksić, Gordana
AU  - Uskoković, Dragan
PY  - 2007
UR  - https://dais.sanu.ac.rs/123456789/6284
AB  - Particles generated of biodegradable material are extensively investigated as carriers
for sustained drug delivery. Studies have been mainly focused on the monitoring of the drug
release and of the rate of the particle degradation. However, the influence of the carrier particles
on the human immune cells was only rarely addressed. In this work, the influence of the
microparticles made of poly-D,L-lactide (PDLLA) on the function of human lymphocytes in a
three-day culture was investigated. PDLLA microparticles have been prepared by a modified
precipitation method and human lymphocytes were isolated from the blood of healthy volunteers
by a Ficoll – density gradient centrifugation. Lymphocyte proliferation test and the cytochalasin
B micronucleus test were used to assess the PDLLA particle effect on the lymphocytes. Results
showed that PDLLA particles did not influence on the proliferation of the human lymphocytes.
On the other hand, changes in the nuclei form, as well as nucleus buddings were observed.
Moreover, the appearance of micronuclei could be detected. All together, these results might
imply genotoxicity of the PDLLA particles, or some of the chemicals used for the particle
preparation/stabilization on the human lymphocytes.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
T1  - Genotoxicity of the poly-D,L-lactide microparticles on the human lymphocytes
SP  - 61
EP  - 61
UR  - https://hdl.handle.net/21.15107/rcub_dais_6284
ER  - 
@conference{
author = "Jovanović, Ivana and Petković, Marijana and Joksić, Gordana and Uskoković, Dragan",
year = "2007",
abstract = "Particles generated of biodegradable material are extensively investigated as carriers
for sustained drug delivery. Studies have been mainly focused on the monitoring of the drug
release and of the rate of the particle degradation. However, the influence of the carrier particles
on the human immune cells was only rarely addressed. In this work, the influence of the
microparticles made of poly-D,L-lactide (PDLLA) on the function of human lymphocytes in a
three-day culture was investigated. PDLLA microparticles have been prepared by a modified
precipitation method and human lymphocytes were isolated from the blood of healthy volunteers
by a Ficoll – density gradient centrifugation. Lymphocyte proliferation test and the cytochalasin
B micronucleus test were used to assess the PDLLA particle effect on the lymphocytes. Results
showed that PDLLA particles did not influence on the proliferation of the human lymphocytes.
On the other hand, changes in the nuclei form, as well as nucleus buddings were observed.
Moreover, the appearance of micronuclei could be detected. All together, these results might
imply genotoxicity of the PDLLA particles, or some of the chemicals used for the particle
preparation/stabilization on the human lymphocytes.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007",
title = "Genotoxicity of the poly-D,L-lactide microparticles on the human lymphocytes",
pages = "61-61",
url = "https://hdl.handle.net/21.15107/rcub_dais_6284"
}
Jovanović, I., Petković, M., Joksić, G.,& Uskoković, D.. (2007). Genotoxicity of the poly-D,L-lactide microparticles on the human lymphocytes. in Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007
Belgrade : Institute of Technical Sciences of SASA., 61-61.
https://hdl.handle.net/21.15107/rcub_dais_6284
Jovanović I, Petković M, Joksić G, Uskoković D. Genotoxicity of the poly-D,L-lactide microparticles on the human lymphocytes. in Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007. 2007;:61-61.
https://hdl.handle.net/21.15107/rcub_dais_6284 .
Jovanović, Ivana, Petković, Marijana, Joksić, Gordana, Uskoković, Dragan, "Genotoxicity of the poly-D,L-lactide microparticles on the human lymphocytes" in Programme and The Book of Abstracts / Ninth Annual Conference YUCOMAT 2007, Herceg Novi, September 10-14, 2007 (2007):61-61,
https://hdl.handle.net/21.15107/rcub_dais_6284 .

Procesiranje mikrosfera poli-D,L-laktid-a u koje je inkorporiran protein

Jovanović, Ivana; Petković, Marijana; Vujčić, Zoran; Uskoković, Dragan

(Beograd : Institut tehničkih nauka SANU, 2007)

TY  - CONF
AU  - Jovanović, Ivana
AU  - Petković, Marijana
AU  - Vujčić, Zoran
AU  - Uskoković, Dragan
PY  - 2007
UR  - https://dais.sanu.ac.rs/123456789/6275
AB  - U svetu trenutno postoji značajna potreba za otkrićem biodegradabilnih mikrosfera kao sistema za kontrolisanu dostavu medikamenata. Glavni nedostatak tradicionalnog načina doziranja medikamenata se ogleda u potrebi za čestim ponavljanjem doza. Koncentracija, trajanje, i biološka aktivnost farmaceutskih agenata se ne mogu kontrolisati. Kako bi se izbegli ovi problemi osmišljena je tehnologija kontrolisanog otpuštanja. Ideja je bila da se terapeutska koncentracija agenta u telu održava tokom produženog vremenskog perioda, otpuštanjem agenta na predvidljiv i kontrolisan način. Inkapsulacija predstavlja efektivan način za kontrolisanu dostavu različitih medikamenata. Dokazano je da efikasnost inkapsulacije i kinetika otpuštanja medikamenata zavise od veličine sintetisanih mikrosfera. Cilj ovog rada je procesiranje mikrosfera od poli-D,L-laktida (PDLLA) modifikovanom precipitacionom metodom. Goveđi serum albumin (BSA) je korišćen kao model protein za mikroinkapsulaciju. Kao surfaktant je korišćen polivinil alkohol (PVA) kako bi se povećala efikasnost inkapsulacije i kako bi se dobile sfere PDLLA željene veličine. Glavni cilj je bio da se ispita uticaj izbora ko-rastvarača (metanol ili etanol), koncentracije PVA, kao i brzine i vremena homogenizacije na morfološke karakteristike mikročestica. Veličina i morfologija čestica se značajno menjaju promenom ovih uslova procesiranja. Može se videti da se pri većim brzinama homogenizacije, kao i sa većim koncentracijama surfaktanta veličina mikrosfera značajno redukuje. Ostali parametri procesa imaju limitiran uticaj na veličinu čestica.
PB  - Beograd : Institut tehničkih nauka SANU
C3  - Program i knjiga apstrakata / Šesta konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 24–26. decembar 2007
T1  - Procesiranje mikrosfera poli-D,L-laktid-a u koje je inkorporiran protein
SP  - 7
EP  - 7
UR  - https://hdl.handle.net/21.15107/rcub_dais_6275
ER  - 
@conference{
author = "Jovanović, Ivana and Petković, Marijana and Vujčić, Zoran and Uskoković, Dragan",
year = "2007",
abstract = "U svetu trenutno postoji značajna potreba za otkrićem biodegradabilnih mikrosfera kao sistema za kontrolisanu dostavu medikamenata. Glavni nedostatak tradicionalnog načina doziranja medikamenata se ogleda u potrebi za čestim ponavljanjem doza. Koncentracija, trajanje, i biološka aktivnost farmaceutskih agenata se ne mogu kontrolisati. Kako bi se izbegli ovi problemi osmišljena je tehnologija kontrolisanog otpuštanja. Ideja je bila da se terapeutska koncentracija agenta u telu održava tokom produženog vremenskog perioda, otpuštanjem agenta na predvidljiv i kontrolisan način. Inkapsulacija predstavlja efektivan način za kontrolisanu dostavu različitih medikamenata. Dokazano je da efikasnost inkapsulacije i kinetika otpuštanja medikamenata zavise od veličine sintetisanih mikrosfera. Cilj ovog rada je procesiranje mikrosfera od poli-D,L-laktida (PDLLA) modifikovanom precipitacionom metodom. Goveđi serum albumin (BSA) je korišćen kao model protein za mikroinkapsulaciju. Kao surfaktant je korišćen polivinil alkohol (PVA) kako bi se povećala efikasnost inkapsulacije i kako bi se dobile sfere PDLLA željene veličine. Glavni cilj je bio da se ispita uticaj izbora ko-rastvarača (metanol ili etanol), koncentracije PVA, kao i brzine i vremena homogenizacije na morfološke karakteristike mikročestica. Veličina i morfologija čestica se značajno menjaju promenom ovih uslova procesiranja. Može se videti da se pri većim brzinama homogenizacije, kao i sa većim koncentracijama surfaktanta veličina mikrosfera značajno redukuje. Ostali parametri procesa imaju limitiran uticaj na veličinu čestica.",
publisher = "Beograd : Institut tehničkih nauka SANU",
journal = "Program i knjiga apstrakata / Šesta konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 24–26. decembar 2007",
title = "Procesiranje mikrosfera poli-D,L-laktid-a u koje je inkorporiran protein",
pages = "7-7",
url = "https://hdl.handle.net/21.15107/rcub_dais_6275"
}
Jovanović, I., Petković, M., Vujčić, Z.,& Uskoković, D.. (2007). Procesiranje mikrosfera poli-D,L-laktid-a u koje je inkorporiran protein. in Program i knjiga apstrakata / Šesta konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 24–26. decembar 2007
Beograd : Institut tehničkih nauka SANU., 7-7.
https://hdl.handle.net/21.15107/rcub_dais_6275
Jovanović I, Petković M, Vujčić Z, Uskoković D. Procesiranje mikrosfera poli-D,L-laktid-a u koje je inkorporiran protein. in Program i knjiga apstrakata / Šesta konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 24–26. decembar 2007. 2007;:7-7.
https://hdl.handle.net/21.15107/rcub_dais_6275 .
Jovanović, Ivana, Petković, Marijana, Vujčić, Zoran, Uskoković, Dragan, "Procesiranje mikrosfera poli-D,L-laktid-a u koje je inkorporiran protein" in Program i knjiga apstrakata / Šesta konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 24–26. decembar 2007 (2007):7-7,
https://hdl.handle.net/21.15107/rcub_dais_6275 .

PDLLA Microparticles Containing BSA: Effect of Formulation Variables on Size Distribution

Jovanović, Ivana; Petković, Marijana; Vujčić, Zoran; Jordović, Branka; Ignjatović, Nenad; Uskoković, Dragan

(2007)

TY  - CONF
AU  - Jovanović, Ivana
AU  - Petković, Marijana
AU  - Vujčić, Zoran
AU  - Jordović, Branka
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2007
UR  - https://dais.sanu.ac.rs/123456789/319
AB  - Poster presented at the 9th Conference of the Yugoslav Materials Research Society - YUCOMAT 2007, Herceg Novi, Crna Gora, September 10-14, 2007.
T1  - PDLLA Microparticles Containing BSA: Effect of Formulation Variables on Size Distribution
UR  - https://hdl.handle.net/21.15107/rcub_dais_319
ER  - 
@conference{
author = "Jovanović, Ivana and Petković, Marijana and Vujčić, Zoran and Jordović, Branka and Ignjatović, Nenad and Uskoković, Dragan",
year = "2007",
abstract = "Poster presented at the 9th Conference of the Yugoslav Materials Research Society - YUCOMAT 2007, Herceg Novi, Crna Gora, September 10-14, 2007.",
title = "PDLLA Microparticles Containing BSA: Effect of Formulation Variables on Size Distribution",
url = "https://hdl.handle.net/21.15107/rcub_dais_319"
}
Jovanović, I., Petković, M., Vujčić, Z., Jordović, B., Ignjatović, N.,& Uskoković, D.. (2007). PDLLA Microparticles Containing BSA: Effect of Formulation Variables on Size Distribution. .
https://hdl.handle.net/21.15107/rcub_dais_319
Jovanović I, Petković M, Vujčić Z, Jordović B, Ignjatović N, Uskoković D. PDLLA Microparticles Containing BSA: Effect of Formulation Variables on Size Distribution. 2007;.
https://hdl.handle.net/21.15107/rcub_dais_319 .
Jovanović, Ivana, Petković, Marijana, Vujčić, Zoran, Jordović, Branka, Ignjatović, Nenad, Uskoković, Dragan, "PDLLA Microparticles Containing BSA: Effect of Formulation Variables on Size Distribution" (2007),
https://hdl.handle.net/21.15107/rcub_dais_319 .