TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, Nenad
AU  - Rajković, Jelena
AU  - Kenić Marinković, Dragana
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Uskoković, Dragan
PY  - 2014
UR  - https://dais.sanu.ac.rs/123456789/558
AB  - Recent studies have shown that the behavior of nanoparticles in in vivo conditions is not solely dependant on their physical properties, such are size and shape. The surface of nanoparticles in biological fluids interacts with biomolecules such are proteins, adsorbs these molecules, and leads to formation of nanoparticle-biomoelcular complex known as “protein corona”. This protein corona changes the properties of nanoparticles and their behavior in vivo. In this work three types of nanomaterial based on Hap and polymers were incubated in rats plasma, and the identification and quantification of proteins in protein corona that had formed around these nanoparticles, was done by means of electrophoresis and mass spectrophotometery.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts
T1  - Interaction of nanoparticles and biological fluids
SP  - 113
EP  - 113
UR  - https://hdl.handle.net/21.15107/rcub_dais_558
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, Nenad and Rajković, Jelena and Kenić Marinković, Dragana and Najman, Stevo and Mihailović, Dragan and Uskoković, Dragan",
year = "2014",
abstract = "Recent studies have shown that the behavior of nanoparticles in in vivo conditions is not solely dependant on their physical properties, such are size and shape. The surface of nanoparticles in biological fluids interacts with biomolecules such are proteins, adsorbs these molecules, and leads to formation of nanoparticle-biomoelcular complex known as “protein corona”. This protein corona changes the properties of nanoparticles and their behavior in vivo. In this work three types of nanomaterial based on Hap and polymers were incubated in rats plasma, and the identification and quantification of proteins in protein corona that had formed around these nanoparticles, was done by means of electrophoresis and mass spectrophotometery.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts",
title = "Interaction of nanoparticles and biological fluids",
pages = "113-113",
url = "https://hdl.handle.net/21.15107/rcub_dais_558"
}

Ajduković, Z., Ignjatović, N., Petrović, N., Rajković, J., Kenić Marinković, D., Najman, S., Mihailović, D.,& Uskoković, D.. (2014). Interaction of nanoparticles and biological fluids. in The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 113-113.
https://hdl.handle.net/21.15107/rcub_dais_558

Ajduković Z, Ignjatović N, Petrović N, Rajković J, Kenić Marinković D, Najman S, Mihailović D, Uskoković D. Interaction of nanoparticles and biological fluids. in The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts. 2014;:113-113.
https://hdl.handle.net/21.15107/rcub_dais_558 .

Ajduković, Zorica, Ignjatović, Nenad, Petrović, Nenad, Rajković, Jelena, Kenić Marinković, Dragana, Najman, Stevo, Mihailović, Dragan, Uskoković, Dragan, "Interaction of nanoparticles and biological fluids" in The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts (2014):113-113,
https://hdl.handle.net/21.15107/rcub_dais_558 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Đorđević, Nadica
AU  - Petrović, Nenad
AU  - Ignjatović, Nenad
AU  - Kenić Marinković, Dragana
AU  - Uskoković, Dragan
PY  - 2013
UR  - https://dais.sanu.ac.rs/123456789/432
AB  - The loss of teeth and damage to the jaw bone occur under different circumstances. The deficit may be the result of wearing inadequate dentures, residual ridge resorption, osteoporosis, periodontal disease, trauma, tumors, radiation, etc. The deficit of bone tissue can be a substantial problem because it prevents adequate prosthetic patient care and restoration of disturbed functions of stomatognathic system. With such patients, there is often a need for preprosthetic surgical procedure through the application of various techniques and materials in order to resolve aftermentioned bone shortcomings. The most appropriate biological materials for the reconstruction are autogenous bone graft and artificial bone. With the development of technology and specific
biomaterials it is tried to avoid situations that require autogenous bone grafting, since it involvs long surgical procedure with the possibility of postoperative complications. The application of synthetic biomaterials, whose properties are similar to natural hydroxyapatite, promotes the biological potential for bone tissue repair. Synthetic biomaterials have great biocompatibility and sterility and do not act antigenicaly. The disadvantages of this material are overcome by the addition of organic polymers. Thanks to the stability and flexibility of hydroxyapatite structure, a large number of ionic changes are possible, both cationic and anionic, which improve the characteristics of synthetic hydroxyapatite. Biomaterials that include different drugs, such as antibiotics, vitamins and other preparations, could be used for the treatment of complications after surgical procedures and infection of bone tissue. Our experimental studies indicate that biomaterials based on hydroxyapatite are valuable materials that can be used for preprosthetic surgical preparation.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Twelfth Young Researchers' Conference Materials Sciences and Engineering December 11-13, 2013, Belgrade, Serbia
T1  - Biomaterials and their application in preprosthetic surgical procedure
SP  - 5
EP  - 5
UR  - https://hdl.handle.net/21.15107/rcub_dais_432
ER  - 

@conference{
author = "Ajduković, Zorica and Đorđević, Nadica and Petrović, Nenad and Ignjatović, Nenad and Kenić Marinković, Dragana and Uskoković, Dragan",
year = "2013",
abstract = "The loss of teeth and damage to the jaw bone occur under different circumstances. The deficit may be the result of wearing inadequate dentures, residual ridge resorption, osteoporosis, periodontal disease, trauma, tumors, radiation, etc. The deficit of bone tissue can be a substantial problem because it prevents adequate prosthetic patient care and restoration of disturbed functions of stomatognathic system. With such patients, there is often a need for preprosthetic surgical procedure through the application of various techniques and materials in order to resolve aftermentioned bone shortcomings. The most appropriate biological materials for the reconstruction are autogenous bone graft and artificial bone. With the development of technology and specific
biomaterials it is tried to avoid situations that require autogenous bone grafting, since it involvs long surgical procedure with the possibility of postoperative complications. The application of synthetic biomaterials, whose properties are similar to natural hydroxyapatite, promotes the biological potential for bone tissue repair. Synthetic biomaterials have great biocompatibility and sterility and do not act antigenicaly. The disadvantages of this material are overcome by the addition of organic polymers. Thanks to the stability and flexibility of hydroxyapatite structure, a large number of ionic changes are possible, both cationic and anionic, which improve the characteristics of synthetic hydroxyapatite. Biomaterials that include different drugs, such as antibiotics, vitamins and other preparations, could be used for the treatment of complications after surgical procedures and infection of bone tissue. Our experimental studies indicate that biomaterials based on hydroxyapatite are valuable materials that can be used for preprosthetic surgical preparation.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Twelfth Young Researchers' Conference Materials Sciences and Engineering December 11-13, 2013, Belgrade, Serbia",
title = "Biomaterials and their application in preprosthetic surgical procedure",
pages = "5-5",
url = "https://hdl.handle.net/21.15107/rcub_dais_432"
}

Ajduković, Z., Đorđević, N., Petrović, N., Ignjatović, N., Kenić Marinković, D.,& Uskoković, D.. (2013). Biomaterials and their application in preprosthetic surgical procedure. in Program and the Book of Abstracts / Twelfth Young Researchers' Conference Materials Sciences and Engineering December 11-13, 2013, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 5-5.
https://hdl.handle.net/21.15107/rcub_dais_432

Ajduković Z, Đorđević N, Petrović N, Ignjatović N, Kenić Marinković D, Uskoković D. Biomaterials and their application in preprosthetic surgical procedure. in Program and the Book of Abstracts / Twelfth Young Researchers' Conference Materials Sciences and Engineering December 11-13, 2013, Belgrade, Serbia. 2013;:5-5.
https://hdl.handle.net/21.15107/rcub_dais_432 .

Ajduković, Zorica, Đorđević, Nadica, Petrović, Nenad, Ignjatović, Nenad, Kenić Marinković, Dragana, Uskoković, Dragan, "Biomaterials and their application in preprosthetic surgical procedure" in Program and the Book of Abstracts / Twelfth Young Researchers' Conference Materials Sciences and Engineering December 11-13, 2013, Belgrade, Serbia (2013):5-5,
https://hdl.handle.net/21.15107/rcub_dais_432 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, N.
AU  - Rajković, J.
AU  - Kenić Marinković, Dragana
AU  - Najman, Stevo
AU  - Uskoković, Dragan
PY  - 2013
UR  - https://dais.sanu.ac.rs/123456789/388
AB  - The lack of bone in the jaw tegmenta inflicts major problem and leads to an inability to adequately treat stomatoprosthetic patients. If the bone tissue damage is minor, the balanced activities of osteoblasts and bone osteoclasts can repair it independently. If the damage is bigger it is necessary to support the biological potential to repair the bone, and for that reason nanoparticle
biomaterial Ca / Co-HAp was used in this study. The research was done on rats with uniform anatomical and physiological characteristics. Assessment of repair and consolidation of the jaw bone tegmenta was performed by istomorphometric and SEM analysis. The best results were obtained in the experimental group of animals where the Ca / Co-Hap was mixed with autologous
plasma. Following the implementation of the above mentioned nanocomposites, a significant formation of new bone was evident on the SEM analysis, as well as the rising of histomorphometric parameters of bone formation, which indicates that the Ca / Co-HAp nanocomposite is the material of choice for the rapid regeneration and repair of bone jaw tegmenta.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts
T1  - Nanoparticles Ca/Co-HAp in the treatment of weakened bones jaw tegmenta
SP  - 147
EP  - 147
UR  - https://hdl.handle.net/21.15107/rcub_dais_388
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, N. and Rajković, J. and Kenić Marinković, Dragana and Najman, Stevo and Uskoković, Dragan",
year = "2013",
abstract = "The lack of bone in the jaw tegmenta inflicts major problem and leads to an inability to adequately treat stomatoprosthetic patients. If the bone tissue damage is minor, the balanced activities of osteoblasts and bone osteoclasts can repair it independently. If the damage is bigger it is necessary to support the biological potential to repair the bone, and for that reason nanoparticle
biomaterial Ca / Co-HAp was used in this study. The research was done on rats with uniform anatomical and physiological characteristics. Assessment of repair and consolidation of the jaw bone tegmenta was performed by istomorphometric and SEM analysis. The best results were obtained in the experimental group of animals where the Ca / Co-Hap was mixed with autologous
plasma. Following the implementation of the above mentioned nanocomposites, a significant formation of new bone was evident on the SEM analysis, as well as the rising of histomorphometric parameters of bone formation, which indicates that the Ca / Co-HAp nanocomposite is the material of choice for the rapid regeneration and repair of bone jaw tegmenta.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts",
title = "Nanoparticles Ca/Co-HAp in the treatment of weakened bones jaw tegmenta",
pages = "147-147",
url = "https://hdl.handle.net/21.15107/rcub_dais_388"
}

Ajduković, Z., Ignjatović, N., Petrović, N., Rajković, J., Kenić Marinković, D., Najman, S.,& Uskoković, D.. (2013). Nanoparticles Ca/Co-HAp in the treatment of weakened bones jaw tegmenta. in The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 147-147.
https://hdl.handle.net/21.15107/rcub_dais_388

Ajduković Z, Ignjatović N, Petrović N, Rajković J, Kenić Marinković D, Najman S, Uskoković D. Nanoparticles Ca/Co-HAp in the treatment of weakened bones jaw tegmenta. in The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts. 2013;:147-147.
https://hdl.handle.net/21.15107/rcub_dais_388 .

Ajduković, Zorica, Ignjatović, Nenad, Petrović, N., Rajković, J., Kenić Marinković, Dragana, Najman, Stevo, Uskoković, Dragan, "Nanoparticles Ca/Co-HAp in the treatment of weakened bones jaw tegmenta" in The Fifteenth Annual Conference YUCOMAT 2013: Programme and the Book of Abstracts (2013):147-147,
https://hdl.handle.net/21.15107/rcub_dais_388 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, N.
AU  - Najman, Stevo
AU  - Rajković, J.
AU  - Kenić Marinković, Dragana
AU  - Krstić, V.
AU  - Uskoković, Dragan
PY  - 2012
UR  - https://dais.sanu.ac.rs/123456789/497
AB  - Huge range of tested biomaterials in recent decades has emerged as an ideal scaffold for cell growth, but few have demonstrated clinical efficacy. Among them, synthetic hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the most promising because of its biocompatibility, bioactivity, and osteoconductivity. Biocompatibility represents the primary concern for any material to be used as a substitute for natural tissue. Hydroxyapatite particles interact with numerous cellular systems in vivo, and some of these interactions may lead to cell damage and to stimulate platelet activation, coagulation and thrombus formation. The aim of this work was to examine the hemocompatibility of nanocalcium hydroxyapatite substituted with 5% and 12% cobalt (Ca /CoHAp) and hydroxyapatite/polylactidcoglicolid (HAp / PLGA) in relation to pure HAp by testing their hemolytic activities. The results show the discrepancy in hemolytic activity of implanted matherials. The degree of crystallinity of samples had a more dominant influence on hemolysis than the percentage of substituted cobalt. Hemolysis ratios of the nanocalcium hydroxyapatite substituted with cobalt samples were below 3%, indicating good blood compatibility and that they are promising for medical application.
PB  - Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade
C3  - Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts
T1  - Hemolytic activity of bioactive nanocomposites
SP  - 49
EP  - 49
UR  - https://hdl.handle.net/21.15107/rcub_dais_497
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, N. and Najman, Stevo and Rajković, J. and Kenić Marinković, Dragana and Krstić, V. and Uskoković, Dragan",
year = "2012",
abstract = "Huge range of tested biomaterials in recent decades has emerged as an ideal scaffold for cell growth, but few have demonstrated clinical efficacy. Among them, synthetic hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the most promising because of its biocompatibility, bioactivity, and osteoconductivity. Biocompatibility represents the primary concern for any material to be used as a substitute for natural tissue. Hydroxyapatite particles interact with numerous cellular systems in vivo, and some of these interactions may lead to cell damage and to stimulate platelet activation, coagulation and thrombus formation. The aim of this work was to examine the hemocompatibility of nanocalcium hydroxyapatite substituted with 5% and 12% cobalt (Ca /CoHAp) and hydroxyapatite/polylactidcoglicolid (HAp / PLGA) in relation to pure HAp by testing their hemolytic activities. The results show the discrepancy in hemolytic activity of implanted matherials. The degree of crystallinity of samples had a more dominant influence on hemolysis than the percentage of substituted cobalt. Hemolysis ratios of the nanocalcium hydroxyapatite substituted with cobalt samples were below 3%, indicating good blood compatibility and that they are promising for medical application.",
publisher = "Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade",
journal = "Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts",
title = "Hemolytic activity of bioactive nanocomposites",
pages = "49-49",
url = "https://hdl.handle.net/21.15107/rcub_dais_497"
}

Ajduković, Z., Ignjatović, N., Petrović, N., Najman, S., Rajković, J., Kenić Marinković, D., Krstić, V.,& Uskoković, D.. (2012). Hemolytic activity of bioactive nanocomposites. in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts
Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade., 49-49.
https://hdl.handle.net/21.15107/rcub_dais_497

Ajduković Z, Ignjatović N, Petrović N, Najman S, Rajković J, Kenić Marinković D, Krstić V, Uskoković D. Hemolytic activity of bioactive nanocomposites. in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts. 2012;:49-49.
https://hdl.handle.net/21.15107/rcub_dais_497 .

Ajduković, Zorica, Ignjatović, Nenad, Petrović, N., Najman, Stevo, Rajković, J., Kenić Marinković, Dragana, Krstić, V., Uskoković, Dragan, "Hemolytic activity of bioactive nanocomposites" in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts (2012):49-49,
https://hdl.handle.net/21.15107/rcub_dais_497 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Rajković, Jelena
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Petrović, D.
AU  - Kenić Marinković, Dragana
AU  - Uskoković, Dragan
PY  - 2012
UR  - https://dais.sanu.ac.rs/123456789/498
AB  - Bone loss during the systemic osteoporosis has an important role in dentistry and medicine. The aim of the study was the application of bioactive micro and nanocomposite materials, alone, and in combination with autologous plasma in osteoporotic jaw bones of rats with artificially induced osteoporosis. The effect of these composites was measured by histomorphometric and atomic absorption spectrophotometric analysis. According to the best obtained results in regeneration and recovery of the resorbed alveolar bone, it can be concluded that nanocomposite combined with autologous plasma may be the material of choice to replace the osteoporotic damaged jaw bone.
PB  - Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade
C3  - Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts
T1  - Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges
SP  - 103
EP  - 103
UR  - https://hdl.handle.net/21.15107/rcub_dais_498
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Rajković, Jelena and Najman, Stevo and Mihailović, Dragan and Petrović, D. and Kenić Marinković, Dragana and Uskoković, Dragan",
year = "2012",
abstract = "Bone loss during the systemic osteoporosis has an important role in dentistry and medicine. The aim of the study was the application of bioactive micro and nanocomposite materials, alone, and in combination with autologous plasma in osteoporotic jaw bones of rats with artificially induced osteoporosis. The effect of these composites was measured by histomorphometric and atomic absorption spectrophotometric analysis. According to the best obtained results in regeneration and recovery of the resorbed alveolar bone, it can be concluded that nanocomposite combined with autologous plasma may be the material of choice to replace the osteoporotic damaged jaw bone.",
publisher = "Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade",
journal = "Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts",
title = "Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges",
pages = "103-103",
url = "https://hdl.handle.net/21.15107/rcub_dais_498"
}

Ajduković, Z., Ignjatović, N., Rajković, J., Najman, S., Mihailović, D., Petrović, D., Kenić Marinković, D.,& Uskoković, D.. (2012). Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges. in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts
Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade., 103-103.
https://hdl.handle.net/21.15107/rcub_dais_498

Ajduković Z, Ignjatović N, Rajković J, Najman S, Mihailović D, Petrović D, Kenić Marinković D, Uskoković D. Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges. in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts. 2012;:103-103.
https://hdl.handle.net/21.15107/rcub_dais_498 .

Ajduković, Zorica, Ignjatović, Nenad, Rajković, Jelena, Najman, Stevo, Mihailović, Dragan, Petrović, D., Kenić Marinković, Dragana, Uskoković, Dragan, "Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges" in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts (2012):103-103,
https://hdl.handle.net/21.15107/rcub_dais_498 .