TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Ajduković, Zorica
AU  - Rajković, Jelena
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Uskoković, Dragan
PY  - 2015
UR  - https://dais.sanu.ac.rs/123456789/3547
AB  - Hydroxyapatite (HAp) is an extensively studied material with known biocompatible and osteoconductive properties in bone tissue reconstruction. The improvement of the osteogenetic potential of HAp has been tested through modification of its structure, by replacing Ca2+ ions with Co2+ ions. In our study, we comparatively analyze the osteogenetic potential of the synthesized HAp and Co2+-substituted HAp (HAp/Co) designed on the nano-scale with the aim of specifically stimulating osteogenesis in vivo. We present a quantitative study of the microscopic organization and structure of the newly formed tissue in a bone defect after 12 weeks and 24 weeks. A quantitative analysis of the calcium, magnesium and phosphorus content in the defect and its close environment was used to determine the deposition of minerals after bone reconstruction. The defect reconstructed with HAp/Co nanoparticles (Co2+ content 12 wt%) was filled with a new tissue matrix composed of dense collagen fibers containing centers of mineralization after 24 weeks. The mineral deposition rate was also higher when the defect was reconstructed with HAp/Co than when it was filled with pure HAp. A histological analysis confirmed that the alveolar bone, in which osteoporosis-induced defects were repaired using HAp/Co nanoparticles, was recuperated. © 2015 Jilin University.
PB  - Elsevier
T2  - Journal of Bionic Engineering
T1  - Enhanced Osteogenesis of Nanosized Cobalt-substituted Hydroxyapatite
SP  - 604
EP  - 612
VL  - 12
IS  - 4
DO  - 10.1016/S1672-6529(14)60150-5
UR  - https://hdl.handle.net/21.15107/rcub_dais_3547
ER  - 

@article{
author = "Ignjatović, Nenad and Ajduković, Zorica and Rajković, Jelena and Najman, Stevo and Mihailović, Dragan and Uskoković, Dragan",
year = "2015",
abstract = "Hydroxyapatite (HAp) is an extensively studied material with known biocompatible and osteoconductive properties in bone tissue reconstruction. The improvement of the osteogenetic potential of HAp has been tested through modification of its structure, by replacing Ca2+ ions with Co2+ ions. In our study, we comparatively analyze the osteogenetic potential of the synthesized HAp and Co2+-substituted HAp (HAp/Co) designed on the nano-scale with the aim of specifically stimulating osteogenesis in vivo. We present a quantitative study of the microscopic organization and structure of the newly formed tissue in a bone defect after 12 weeks and 24 weeks. A quantitative analysis of the calcium, magnesium and phosphorus content in the defect and its close environment was used to determine the deposition of minerals after bone reconstruction. The defect reconstructed with HAp/Co nanoparticles (Co2+ content 12 wt%) was filled with a new tissue matrix composed of dense collagen fibers containing centers of mineralization after 24 weeks. The mineral deposition rate was also higher when the defect was reconstructed with HAp/Co than when it was filled with pure HAp. A histological analysis confirmed that the alveolar bone, in which osteoporosis-induced defects were repaired using HAp/Co nanoparticles, was recuperated. © 2015 Jilin University.",
publisher = "Elsevier",
journal = "Journal of Bionic Engineering",
title = "Enhanced Osteogenesis of Nanosized Cobalt-substituted Hydroxyapatite",
pages = "604-612",
volume = "12",
number = "4",
doi = "10.1016/S1672-6529(14)60150-5",
url = "https://hdl.handle.net/21.15107/rcub_dais_3547"
}

Ignjatović, N., Ajduković, Z., Rajković, J., Najman, S., Mihailović, D.,& Uskoković, D.. (2015). Enhanced Osteogenesis of Nanosized Cobalt-substituted Hydroxyapatite. in Journal of Bionic Engineering
Elsevier., 12(4), 604-612.
https://doi.org/10.1016/S1672-6529(14)60150-5
https://hdl.handle.net/21.15107/rcub_dais_3547

Ignjatović N, Ajduković Z, Rajković J, Najman S, Mihailović D, Uskoković D. Enhanced Osteogenesis of Nanosized Cobalt-substituted Hydroxyapatite. in Journal of Bionic Engineering. 2015;12(4):604-612.
doi:10.1016/S1672-6529(14)60150-5
https://hdl.handle.net/21.15107/rcub_dais_3547 .

Ignjatović, Nenad, Ajduković, Zorica, Rajković, Jelena, Najman, Stevo, Mihailović, Dragan, Uskoković, Dragan, "Enhanced Osteogenesis of Nanosized Cobalt-substituted Hydroxyapatite" in Journal of Bionic Engineering, 12, no. 4 (2015):604-612,
https://doi.org/10.1016/S1672-6529(14)60150-5 .,
https://hdl.handle.net/21.15107/rcub_dais_3547 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, Nenad
AU  - Rajković, Jelena
AU  - Kenić Marinković, Dragana
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Uskoković, Dragan
PY  - 2014
UR  - https://dais.sanu.ac.rs/123456789/558
AB  - Recent studies have shown that the behavior of nanoparticles in in vivo conditions is not solely dependant on their physical properties, such are size and shape. The surface of nanoparticles in biological fluids interacts with biomolecules such are proteins, adsorbs these molecules, and leads to formation of nanoparticle-biomoelcular complex known as “protein corona”. This protein corona changes the properties of nanoparticles and their behavior in vivo. In this work three types of nanomaterial based on Hap and polymers were incubated in rats plasma, and the identification and quantification of proteins in protein corona that had formed around these nanoparticles, was done by means of electrophoresis and mass spectrophotometery.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts
T1  - Interaction of nanoparticles and biological fluids
SP  - 113
EP  - 113
UR  - https://hdl.handle.net/21.15107/rcub_dais_558
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, Nenad and Rajković, Jelena and Kenić Marinković, Dragana and Najman, Stevo and Mihailović, Dragan and Uskoković, Dragan",
year = "2014",
abstract = "Recent studies have shown that the behavior of nanoparticles in in vivo conditions is not solely dependant on their physical properties, such are size and shape. The surface of nanoparticles in biological fluids interacts with biomolecules such are proteins, adsorbs these molecules, and leads to formation of nanoparticle-biomoelcular complex known as “protein corona”. This protein corona changes the properties of nanoparticles and their behavior in vivo. In this work three types of nanomaterial based on Hap and polymers were incubated in rats plasma, and the identification and quantification of proteins in protein corona that had formed around these nanoparticles, was done by means of electrophoresis and mass spectrophotometery.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts",
title = "Interaction of nanoparticles and biological fluids",
pages = "113-113",
url = "https://hdl.handle.net/21.15107/rcub_dais_558"
}

Ajduković, Z., Ignjatović, N., Petrović, N., Rajković, J., Kenić Marinković, D., Najman, S., Mihailović, D.,& Uskoković, D.. (2014). Interaction of nanoparticles and biological fluids. in The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 113-113.
https://hdl.handle.net/21.15107/rcub_dais_558

Ajduković Z, Ignjatović N, Petrović N, Rajković J, Kenić Marinković D, Najman S, Mihailović D, Uskoković D. Interaction of nanoparticles and biological fluids. in The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts. 2014;:113-113.
https://hdl.handle.net/21.15107/rcub_dais_558 .

Ajduković, Zorica, Ignjatović, Nenad, Petrović, Nenad, Rajković, Jelena, Kenić Marinković, Dragana, Najman, Stevo, Mihailović, Dragan, Uskoković, Dragan, "Interaction of nanoparticles and biological fluids" in The Sixteenth Annual Conference YUCOMAT 2014: Programme and the Book of Abstracts (2014):113-113,
https://hdl.handle.net/21.15107/rcub_dais_558 .

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Ajduković, Zorica
AU  - Savić, Vojin
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Vasiljević, Perica
AU  - Stojanović, Zoran S.
AU  - Uskoković, Vuk
AU  - Uskoković, Dragan
PY  - 2013
UR  - https://dais.sanu.ac.rs/123456789/353
AB  - Indications exist that paramagnetic calcium phosphates may be able to promote regeneration of bone faster than their regular, diamagnetic counterparts. In this study, analyzed was the influence of paramagnetic cobalt-substituted hydroxyapatite nanoparticles on osteoporotic alveolar bone regeneration in rats. Simultaneously, biocompatibility of the material was tested in vitro, on osteoblastic MC3T3-E1 and epithelial Caco-2 cells in culture. The material was shown to be biocompatible and nontoxic when added to epithelial monolayers in vitro, while it caused a substantial decrease in the cell viability as well as deformation of the cytoskeleton and cell morphology when incubated with the osteoblastic cells. In the course of 6 months after the implantation of the material containing different amounts of cobalt, ranging from 5 to 12 wt%, in the osteoporotic alveolar bone of the lower jaw, the following parameters were investigated: histopathological parameters, alkaline phosphatase and alveolar bone density. The best result in terms of osteoporotic bone tissue regeneration was observed for hydroxyapatite nanoparticles with the largest content of cobalt ions. The histological analysis showed a high level of reparatory ability of the nanoparticulate material implanted in the bone defect, paralleled by a corresponding increase in the alveolar bone density. The combined effect of growth factors from autologous plasma admixed to cobalt-substituted hydroxyapatite was furthermore shown to have a crucial effect on the augmented osteoporotic bone regeneration upon the implantation of the biomaterial investigated in this study.
PB  - Springer
T2  - Journal of Materials Science: Materials in Medicine
T1  - Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones
SP  - 343
EP  - 354
VL  - 24
IS  - 2
DO  - 10.1007/s10856-012-4793-1
UR  - https://hdl.handle.net/21.15107/rcub_dais_353
ER  - 

@article{
author = "Ignjatović, Nenad and Ajduković, Zorica and Savić, Vojin and Najman, Stevo and Mihailović, Dragan and Vasiljević, Perica and Stojanović, Zoran S. and Uskoković, Vuk and Uskoković, Dragan",
year = "2013",
abstract = "Indications exist that paramagnetic calcium phosphates may be able to promote regeneration of bone faster than their regular, diamagnetic counterparts. In this study, analyzed was the influence of paramagnetic cobalt-substituted hydroxyapatite nanoparticles on osteoporotic alveolar bone regeneration in rats. Simultaneously, biocompatibility of the material was tested in vitro, on osteoblastic MC3T3-E1 and epithelial Caco-2 cells in culture. The material was shown to be biocompatible and nontoxic when added to epithelial monolayers in vitro, while it caused a substantial decrease in the cell viability as well as deformation of the cytoskeleton and cell morphology when incubated with the osteoblastic cells. In the course of 6 months after the implantation of the material containing different amounts of cobalt, ranging from 5 to 12 wt%, in the osteoporotic alveolar bone of the lower jaw, the following parameters were investigated: histopathological parameters, alkaline phosphatase and alveolar bone density. The best result in terms of osteoporotic bone tissue regeneration was observed for hydroxyapatite nanoparticles with the largest content of cobalt ions. The histological analysis showed a high level of reparatory ability of the nanoparticulate material implanted in the bone defect, paralleled by a corresponding increase in the alveolar bone density. The combined effect of growth factors from autologous plasma admixed to cobalt-substituted hydroxyapatite was furthermore shown to have a crucial effect on the augmented osteoporotic bone regeneration upon the implantation of the biomaterial investigated in this study.",
publisher = "Springer",
journal = "Journal of Materials Science: Materials in Medicine",
title = "Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones",
pages = "343-354",
volume = "24",
number = "2",
doi = "10.1007/s10856-012-4793-1",
url = "https://hdl.handle.net/21.15107/rcub_dais_353"
}

Ignjatović, N., Ajduković, Z., Savić, V., Najman, S., Mihailović, D., Vasiljević, P., Stojanović, Z. S., Uskoković, V.,& Uskoković, D.. (2013). Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones. in Journal of Materials Science: Materials in Medicine
Springer., 24(2), 343-354.
https://doi.org/10.1007/s10856-012-4793-1
https://hdl.handle.net/21.15107/rcub_dais_353

Ignjatović N, Ajduković Z, Savić V, Najman S, Mihailović D, Vasiljević P, Stojanović ZS, Uskoković V, Uskoković D. Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones. in Journal of Materials Science: Materials in Medicine. 2013;24(2):343-354.
doi:10.1007/s10856-012-4793-1
https://hdl.handle.net/21.15107/rcub_dais_353 .

Ignjatović, Nenad, Ajduković, Zorica, Savić, Vojin, Najman, Stevo, Mihailović, Dragan, Vasiljević, Perica, Stojanović, Zoran S., Uskoković, Vuk, Uskoković, Dragan, "Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones" in Journal of Materials Science: Materials in Medicine, 24, no. 2 (2013):343-354,
https://doi.org/10.1007/s10856-012-4793-1 .,
https://hdl.handle.net/21.15107/rcub_dais_353 .

TY  - JOUR
AU  - Ignjatović, Nenad
AU  - Ajduković, Zorica
AU  - Savić, Vojin
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Vasiljević, Perica
AU  - Stojanović, Zoran S.
AU  - Uskoković, Vuk
AU  - Uskoković, Dragan
PY  - 2013
UR  - https://dais.sanu.ac.rs/123456789/572
AB  - Indications exist that paramagnetic calcium phosphates may be able to promote regeneration of bone faster than their regular, diamagnetic counterparts. In this study, analyzed was the influence of paramagnetic cobalt-substituted hydroxyapatite nanoparticles on osteoporotic alveolar bone regeneration in rats. Simultaneously, biocompatibility of the material was tested in vitro, on osteoblastic MC3T3-E1 and epithelial Caco-2 cells in culture. The material was shown to be biocompatible and nontoxic when added to epithelial monolayers in vitro, while it caused a substantial decrease in the cell viability as well as deformation of the cytoskeleton and cell morphology when incubated with the osteoblastic cells. In the course of 6 months after the implantation of the material containing different amounts of cobalt, ranging from 5 to 12 wt%, in the osteoporotic alveolar bone of the lower jaw, the following parameters were investigated: histopathological parameters, alkaline phosphatase and alveolar bone density. The best result in terms of osteoporotic bone tissue regeneration was observed for hydroxyapatite nanoparticles with the largest content of cobalt ions. The histological analysis showed a high level of reparatory ability of the nanoparticulate material implanted in the bone defect, paralleled by a corresponding increase in the alveolar bone density. The combined effect of growth factors from autologous plasma admixed to cobalt-substituted hydroxyapatite was furthermore shown to have a crucial effect on the augmented osteoporotic bone regeneration upon the implantation of the biomaterial investigated in this study.
T2  - Journal of Materials Science: Materials in Medicine
T1  - Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones
SP  - 343
EP  - 354
VL  - 24
IS  - 2
DO  - 10.1007/s10856-012-4793-1
UR  - https://hdl.handle.net/21.15107/rcub_dais_572
ER  - 

@article{
author = "Ignjatović, Nenad and Ajduković, Zorica and Savić, Vojin and Najman, Stevo and Mihailović, Dragan and Vasiljević, Perica and Stojanović, Zoran S. and Uskoković, Vuk and Uskoković, Dragan",
year = "2013",
abstract = "Indications exist that paramagnetic calcium phosphates may be able to promote regeneration of bone faster than their regular, diamagnetic counterparts. In this study, analyzed was the influence of paramagnetic cobalt-substituted hydroxyapatite nanoparticles on osteoporotic alveolar bone regeneration in rats. Simultaneously, biocompatibility of the material was tested in vitro, on osteoblastic MC3T3-E1 and epithelial Caco-2 cells in culture. The material was shown to be biocompatible and nontoxic when added to epithelial monolayers in vitro, while it caused a substantial decrease in the cell viability as well as deformation of the cytoskeleton and cell morphology when incubated with the osteoblastic cells. In the course of 6 months after the implantation of the material containing different amounts of cobalt, ranging from 5 to 12 wt%, in the osteoporotic alveolar bone of the lower jaw, the following parameters were investigated: histopathological parameters, alkaline phosphatase and alveolar bone density. The best result in terms of osteoporotic bone tissue regeneration was observed for hydroxyapatite nanoparticles with the largest content of cobalt ions. The histological analysis showed a high level of reparatory ability of the nanoparticulate material implanted in the bone defect, paralleled by a corresponding increase in the alveolar bone density. The combined effect of growth factors from autologous plasma admixed to cobalt-substituted hydroxyapatite was furthermore shown to have a crucial effect on the augmented osteoporotic bone regeneration upon the implantation of the biomaterial investigated in this study.",
journal = "Journal of Materials Science: Materials in Medicine",
title = "Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones",
pages = "343-354",
volume = "24",
number = "2",
doi = "10.1007/s10856-012-4793-1",
url = "https://hdl.handle.net/21.15107/rcub_dais_572"
}

Ignjatović, N., Ajduković, Z., Savić, V., Najman, S., Mihailović, D., Vasiljević, P., Stojanović, Z. S., Uskoković, V.,& Uskoković, D.. (2013). Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones. in Journal of Materials Science: Materials in Medicine, 24(2), 343-354.
https://doi.org/10.1007/s10856-012-4793-1
https://hdl.handle.net/21.15107/rcub_dais_572

Ignjatović N, Ajduković Z, Savić V, Najman S, Mihailović D, Vasiljević P, Stojanović ZS, Uskoković V, Uskoković D. Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones. in Journal of Materials Science: Materials in Medicine. 2013;24(2):343-354.
doi:10.1007/s10856-012-4793-1
https://hdl.handle.net/21.15107/rcub_dais_572 .

Ignjatović, Nenad, Ajduković, Zorica, Savić, Vojin, Najman, Stevo, Mihailović, Dragan, Vasiljević, Perica, Stojanović, Zoran S., Uskoković, Vuk, Uskoković, Dragan, "Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bones" in Journal of Materials Science: Materials in Medicine, 24, no. 2 (2013):343-354,
https://doi.org/10.1007/s10856-012-4793-1 .,
https://hdl.handle.net/21.15107/rcub_dais_572 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Ignjatović, Nenad
AU  - Savić, Vojin
AU  - Mihailović, Dragan
AU  - Uskoković, Dragan
PY  - 2012
UR  - https://dais.sanu.ac.rs/123456789/454
AB  - Increased life expectancy in developed countries leads to an increase in the number of musculoskeletal disorders, such as osteoporosis, oasteoratritis thus compromising good dental treatment. There are many drug delivery systems based on hydroxyapatite used in bone tissue regeneration. Vitamin D3 is osteodiferentiation factor which regulates bone formation by increasing osteoblast differentiation and bone mineralization. The aim of this study is to examine new multifunctional nanoparticulate system for local delivery of active form of vitamin D3 by biochemical blood marker and histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks, which have been implanted biomaterials in the artificial bone defect. Biochemical markers of osteogenesis were statistically significant after only 6 weeks of implantation. ALP activity in bone tissue was showed by histochemical analysis as well as high level reparatory skills. Local realized Vitamin D3 contribute to bone formation by increasing osteoblast differentiation and bone mineralization.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts
T1  - Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3
SP  - 121
EP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_dais_454
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Ignjatović, Nenad and Savić, Vojin and Mihailović, Dragan and Uskoković, Dragan",
year = "2012",
abstract = "Increased life expectancy in developed countries leads to an increase in the number of musculoskeletal disorders, such as osteoporosis, oasteoratritis thus compromising good dental treatment. There are many drug delivery systems based on hydroxyapatite used in bone tissue regeneration. Vitamin D3 is osteodiferentiation factor which regulates bone formation by increasing osteoblast differentiation and bone mineralization. The aim of this study is to examine new multifunctional nanoparticulate system for local delivery of active form of vitamin D3 by biochemical blood marker and histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks, which have been implanted biomaterials in the artificial bone defect. Biochemical markers of osteogenesis were statistically significant after only 6 weeks of implantation. ALP activity in bone tissue was showed by histochemical analysis as well as high level reparatory skills. Local realized Vitamin D3 contribute to bone formation by increasing osteoblast differentiation and bone mineralization.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts",
title = "Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3",
pages = "121-121",
url = "https://hdl.handle.net/21.15107/rcub_dais_454"
}

Ajduković, Z., Petrović, M. B., Ignjatović, N., Savić, V., Mihailović, D.,& Uskoković, D.. (2012). Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3. in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 121-121.
https://hdl.handle.net/21.15107/rcub_dais_454

Ajduković Z, Petrović MB, Ignjatović N, Savić V, Mihailović D, Uskoković D. Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3. in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts. 2012;:121-121.
https://hdl.handle.net/21.15107/rcub_dais_454 .

Ajduković, Zorica, Petrović, Milica B., Ignjatović, Nenad, Savić, Vojin, Mihailović, Dragan, Uskoković, Dragan, "Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3" in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts (2012):121-121,
https://hdl.handle.net/21.15107/rcub_dais_454 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Savić, Vojin
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Rajković, J.
AU  - Petrović, N.
AU  - Uskoković, Dragan
PY  - 2012
UR  - https://dais.sanu.ac.rs/123456789/455
AB  - In recent years, calcium hydroxyapatite (HAp) and its substituents are increasingly used in dentistry and medicine. The influence of nanoparticles Ca / Co-HAp in strengthening weak osteoporotic bone jaw tegmenta was tested in an experimental model. The study was conducted on Wistar soy rats, aged 6-8 weeks. The biomaterial was implanted in the osteoporoticly weakened mandible of these animals. The best results in the strengthening of the lower jaw bone tegmenta were achieved 24 weeks after implantation of hydroxyapatite nanoparticles in which the calcium ion was substituted with 12% of cobalt ions. Histochemical parameters of bone synthesis were in a statistically significant increase. SEM analysis showed a high degree of osteogenetic ability of nano-particulate material implanted in the bone defect.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts
T1  - Hydroxyapatite and hydroxyapatite substituents in strengthening of the jaw bone tegmenta
SP  - 121
EP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_dais_455
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Savić, Vojin and Najman, Stevo and Mihailović, Dragan and Rajković, J. and Petrović, N. and Uskoković, Dragan",
year = "2012",
abstract = "In recent years, calcium hydroxyapatite (HAp) and its substituents are increasingly used in dentistry and medicine. The influence of nanoparticles Ca / Co-HAp in strengthening weak osteoporotic bone jaw tegmenta was tested in an experimental model. The study was conducted on Wistar soy rats, aged 6-8 weeks. The biomaterial was implanted in the osteoporoticly weakened mandible of these animals. The best results in the strengthening of the lower jaw bone tegmenta were achieved 24 weeks after implantation of hydroxyapatite nanoparticles in which the calcium ion was substituted with 12% of cobalt ions. Histochemical parameters of bone synthesis were in a statistically significant increase. SEM analysis showed a high degree of osteogenetic ability of nano-particulate material implanted in the bone defect.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts",
title = "Hydroxyapatite and hydroxyapatite substituents in strengthening of the jaw bone tegmenta",
pages = "121-121",
url = "https://hdl.handle.net/21.15107/rcub_dais_455"
}

Ajduković, Z., Ignjatović, N., Savić, V., Najman, S., Mihailović, D., Rajković, J., Petrović, N.,& Uskoković, D.. (2012). Hydroxyapatite and hydroxyapatite substituents in strengthening of the jaw bone tegmenta. in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 121-121.
https://hdl.handle.net/21.15107/rcub_dais_455

Ajduković Z, Ignjatović N, Savić V, Najman S, Mihailović D, Rajković J, Petrović N, Uskoković D. Hydroxyapatite and hydroxyapatite substituents in strengthening of the jaw bone tegmenta. in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts. 2012;:121-121.
https://hdl.handle.net/21.15107/rcub_dais_455 .

Ajduković, Zorica, Ignjatović, Nenad, Savić, Vojin, Najman, Stevo, Mihailović, Dragan, Rajković, J., Petrović, N., Uskoković, Dragan, "Hydroxyapatite and hydroxyapatite substituents in strengthening of the jaw bone tegmenta" in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts (2012):121-121,
https://hdl.handle.net/21.15107/rcub_dais_455 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Rajković, Jelena
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Petrović, D.
AU  - Kenić Marinković, Dragana
AU  - Uskoković, Dragan
PY  - 2012
UR  - https://dais.sanu.ac.rs/123456789/498
AB  - Bone loss during the systemic osteoporosis has an important role in dentistry and medicine. The aim of the study was the application of bioactive micro and nanocomposite materials, alone, and in combination with autologous plasma in osteoporotic jaw bones of rats with artificially induced osteoporosis. The effect of these composites was measured by histomorphometric and atomic absorption spectrophotometric analysis. According to the best obtained results in regeneration and recovery of the resorbed alveolar bone, it can be concluded that nanocomposite combined with autologous plasma may be the material of choice to replace the osteoporotic damaged jaw bone.
PB  - Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade
C3  - Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts
T1  - Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges
SP  - 103
EP  - 103
UR  - https://hdl.handle.net/21.15107/rcub_dais_498
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Rajković, Jelena and Najman, Stevo and Mihailović, Dragan and Petrović, D. and Kenić Marinković, Dragana and Uskoković, Dragan",
year = "2012",
abstract = "Bone loss during the systemic osteoporosis has an important role in dentistry and medicine. The aim of the study was the application of bioactive micro and nanocomposite materials, alone, and in combination with autologous plasma in osteoporotic jaw bones of rats with artificially induced osteoporosis. The effect of these composites was measured by histomorphometric and atomic absorption spectrophotometric analysis. According to the best obtained results in regeneration and recovery of the resorbed alveolar bone, it can be concluded that nanocomposite combined with autologous plasma may be the material of choice to replace the osteoporotic damaged jaw bone.",
publisher = "Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade",
journal = "Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts",
title = "Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges",
pages = "103-103",
url = "https://hdl.handle.net/21.15107/rcub_dais_498"
}

Ajduković, Z., Ignjatović, N., Rajković, J., Najman, S., Mihailović, D., Petrović, D., Kenić Marinković, D.,& Uskoković, D.. (2012). Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges. in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts
Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade., 103-103.
https://hdl.handle.net/21.15107/rcub_dais_498

Ajduković Z, Ignjatović N, Rajković J, Najman S, Mihailović D, Petrović D, Kenić Marinković D, Uskoković D. Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges. in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts. 2012;:103-103.
https://hdl.handle.net/21.15107/rcub_dais_498 .

Ajduković, Zorica, Ignjatović, Nenad, Rajković, Jelena, Najman, Stevo, Mihailović, Dragan, Petrović, D., Kenić Marinković, Dragana, Uskoković, Dragan, "Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges" in Joint Event of the 11th Young Researchers’ Conference: Materials Science and Engineering and the 1st European Early Stage Researches’ Conference on Hydrogen Storage: Program and the Book of Abstracts (2012):103-103,
https://hdl.handle.net/21.15107/rcub_dais_498 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, Nadica
AU  - Ignjatović, Nenad
AU  - Savić, Vojin
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Vasiljević, Perica
AU  - Uskoković, Dragan
PY  - 2011
UR  - https://dais.sanu.ac.rs/123456789/674
AB  - One of the trends in the treatment of reduced bone density is in oral implantology through the use of new biomaterials with paramagnetic properties. In this in vivo study the effect of Ca /Co-HAp nanoparticles (calcium/cobalt-hydroxiapatite) in the regeneration of the reduced alveolar bone density in experimental animals was examined by analyzing both the biochemical and histochemical markers and through analysis of alveolar bone density. The research was carried out on female Westar rats, aged 6-8 weeks, whom have been implanted nanobiomaterial in reduced alveolar bone density. Good results in regeneration of reduced bone density were achieved in six weeks after implantation of the nanoparticles with paramagnetic properties. Biochemical markers of osteogenesis showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect, while X-ray analyses evidenced rise of bone density. Implantation of Ca/Co-Hap enables rapid new formation, thus becoming the material of choice for accelerated reduced bone density regeneration.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts
T1  - Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density
SP  - 161
EP  - 161
UR  - https://hdl.handle.net/21.15107/rcub_dais_674
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, Nadica and Ignjatović, Nenad and Savić, Vojin and Najman, Stevo and Mihailović, Dragan and Vasiljević, Perica and Uskoković, Dragan",
year = "2011",
abstract = "One of the trends in the treatment of reduced bone density is in oral implantology through the use of new biomaterials with paramagnetic properties. In this in vivo study the effect of Ca /Co-HAp nanoparticles (calcium/cobalt-hydroxiapatite) in the regeneration of the reduced alveolar bone density in experimental animals was examined by analyzing both the biochemical and histochemical markers and through analysis of alveolar bone density. The research was carried out on female Westar rats, aged 6-8 weeks, whom have been implanted nanobiomaterial in reduced alveolar bone density. Good results in regeneration of reduced bone density were achieved in six weeks after implantation of the nanoparticles with paramagnetic properties. Biochemical markers of osteogenesis showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect, while X-ray analyses evidenced rise of bone density. Implantation of Ca/Co-Hap enables rapid new formation, thus becoming the material of choice for accelerated reduced bone density regeneration.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts",
title = "Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density",
pages = "161-161",
url = "https://hdl.handle.net/21.15107/rcub_dais_674"
}

Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Savić, V., Najman, S., Mihailović, D., Vasiljević, P.,& Uskoković, D.. (2011). Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density. in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 161-161.
https://hdl.handle.net/21.15107/rcub_dais_674

Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Savić V, Najman S, Mihailović D, Vasiljević P, Uskoković D. Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density. in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts. 2011;:161-161.
https://hdl.handle.net/21.15107/rcub_dais_674 .

Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, Nadica, Ignjatović, Nenad, Savić, Vojin, Najman, Stevo, Mihailović, Dragan, Vasiljević, Perica, Uskoković, Dragan, "Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density" in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts (2011):161-161,
https://hdl.handle.net/21.15107/rcub_dais_674 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Petrović, Nenad
AU  - Savić, Vojin
AU  - Mihailović, Dragan
AU  - Uskoković, Dragan
PY  - 2011
UR  - https://dais.sanu.ac.rs/123456789/690
AB  - Systems for targeted delivery of drugs with high affinity for specific organs, tissues, and cells were introduced at the beginning of the twentieth century. Recently, this concept is attracting much attention. These systems have shown most effective in reducing adverse effects of drugs. In recent years, scientists have created a system of nanoparticles for delivery of vitamin D. Special attention is paid to the role of vitamin D in the division and differentiation of osteoblasts and thus, in its role in osteogenesis. In this regard it was interesting to observe the local effects of the active form of vitamin D3 in osteogenesis, as a part of the system for local delivery. These effects were observed on an experimental model. Three types of nanobiomaterial were implanted in the artificially made defects in rats’ mandibular bone. Six weeks after implantation of hydroxyapatite, hydroxyapatite-coated vitamin D3 and hydroxyapatite nanoparticles coated with vitamin D3 mixed with the polymer, the animals were sacrificed, and the samples of mandibular alveolar bone were taken. The samples were adequately prepared and subjected to histopathological analysis. The best results in regeneration of osteoporotic jaw bone were obtained in the experimental group of animals where the implant was hydroxyapatite-coated vitamin D3 mixed with the polymer. The results show that nanobiomaterials with local delivery of active form of vitamin D3, used in this study, may be materials of the future in the area of weakened jaw bone tissue regeneration.
PB  - Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts
C3  - Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia
T1  - Joint effects of vitamin D and nanobiomaterial in the jaw bone regeneration
SP  - 9
EP  - 9
UR  - https://hdl.handle.net/21.15107/rcub_dais_690
ER  - 

@conference{
author = "Ajduković, Zorica and Ignjatović, Nenad and Petrović, Nenad and Savić, Vojin and Mihailović, Dragan and Uskoković, Dragan",
year = "2011",
abstract = "Systems for targeted delivery of drugs with high affinity for specific organs, tissues, and cells were introduced at the beginning of the twentieth century. Recently, this concept is attracting much attention. These systems have shown most effective in reducing adverse effects of drugs. In recent years, scientists have created a system of nanoparticles for delivery of vitamin D. Special attention is paid to the role of vitamin D in the division and differentiation of osteoblasts and thus, in its role in osteogenesis. In this regard it was interesting to observe the local effects of the active form of vitamin D3 in osteogenesis, as a part of the system for local delivery. These effects were observed on an experimental model. Three types of nanobiomaterial were implanted in the artificially made defects in rats’ mandibular bone. Six weeks after implantation of hydroxyapatite, hydroxyapatite-coated vitamin D3 and hydroxyapatite nanoparticles coated with vitamin D3 mixed with the polymer, the animals were sacrificed, and the samples of mandibular alveolar bone were taken. The samples were adequately prepared and subjected to histopathological analysis. The best results in regeneration of osteoporotic jaw bone were obtained in the experimental group of animals where the implant was hydroxyapatite-coated vitamin D3 mixed with the polymer. The results show that nanobiomaterials with local delivery of active form of vitamin D3, used in this study, may be materials of the future in the area of weakened jaw bone tissue regeneration.",
publisher = "Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts",
journal = "Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia",
title = "Joint effects of vitamin D and nanobiomaterial in the jaw bone regeneration",
pages = "9-9",
url = "https://hdl.handle.net/21.15107/rcub_dais_690"
}

Ajduković, Z., Ignjatović, N., Petrović, N., Savić, V., Mihailović, D.,& Uskoković, D.. (2011). Joint effects of vitamin D and nanobiomaterial in the jaw bone regeneration. in Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts., 9-9.
https://hdl.handle.net/21.15107/rcub_dais_690

Ajduković Z, Ignjatović N, Petrović N, Savić V, Mihailović D, Uskoković D. Joint effects of vitamin D and nanobiomaterial in the jaw bone regeneration. in Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia. 2011;:9-9.
https://hdl.handle.net/21.15107/rcub_dais_690 .

Ajduković, Zorica, Ignjatović, Nenad, Petrović, Nenad, Savić, Vojin, Mihailović, Dragan, Uskoković, Dragan, "Joint effects of vitamin D and nanobiomaterial in the jaw bone regeneration" in Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia (2011):9-9,
https://hdl.handle.net/21.15107/rcub_dais_690 .

TY  - JOUR
AU  - Obradović, Radmila
AU  - Kesić, Ljiljana
AU  - Mihailović, Dragan
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2007
UR  - http://www.quintpub.com/journals/jola/abstract.php?iss2_id=800&article_id=9259
UR  - https://dais.sanu.ac.rs/123456789/13689
AB  - Purpose: The efficacy of soft laser application in the treatment of experimentally created bone defects in rat mandibles filled with biocomposite BCP/PLGA (bicalcium phosphate/polylactide–co-glycolide) was analyzed. Materials and Methods: BCP/PLGA biomaterial was implanted in artificially made defects of rat mandibles. Sixty animals were divided into three separate groups. Group A served as the control. In group B1, the implantation site was submitted to GaAlAs laser irradiation, and in group B2 to HeNe laser irradiation for 5 consecutive days. Two, 6 and 8 weeks after completed laser therapy, the animals were killed, specimens taken and routinely processed, and analyzed histologically and morphometrically. Morphometrical analysis consisted of measuring area, area fraction, integral density, mean density, and density variation of bone tissue. Results: After 2 and 6 weeks, significantly higher values of these parameters were obtained in groups submitted to laser irradiation. Conclusions: The results of this study showed a biostimulative effect of soft laser therapy on BCP/PLGA biomaterial osseointegration and increased bone repair with early bone healing.
T2  - The Journal of Oral Laser Applications
T1  - Comparative Efficacy Analysis of Biomaterials and Soft Lasers in Repair of Bone Defects
SP  - 161
EP  - 166
VL  - 7
IS  - 3
UR  - https://hdl.handle.net/21.15107/rcub_dais_13689
ER  - 

@article{
author = "Obradović, Radmila and Kesić, Ljiljana and Mihailović, Dragan and Ignjatović, Nenad and Uskoković, Dragan",
year = "2007",
abstract = "Purpose: The efficacy of soft laser application in the treatment of experimentally created bone defects in rat mandibles filled with biocomposite BCP/PLGA (bicalcium phosphate/polylactide–co-glycolide) was analyzed. Materials and Methods: BCP/PLGA biomaterial was implanted in artificially made defects of rat mandibles. Sixty animals were divided into three separate groups. Group A served as the control. In group B1, the implantation site was submitted to GaAlAs laser irradiation, and in group B2 to HeNe laser irradiation for 5 consecutive days. Two, 6 and 8 weeks after completed laser therapy, the animals were killed, specimens taken and routinely processed, and analyzed histologically and morphometrically. Morphometrical analysis consisted of measuring area, area fraction, integral density, mean density, and density variation of bone tissue. Results: After 2 and 6 weeks, significantly higher values of these parameters were obtained in groups submitted to laser irradiation. Conclusions: The results of this study showed a biostimulative effect of soft laser therapy on BCP/PLGA biomaterial osseointegration and increased bone repair with early bone healing.",
journal = "The Journal of Oral Laser Applications",
title = "Comparative Efficacy Analysis of Biomaterials and Soft Lasers in Repair of Bone Defects",
pages = "161-166",
volume = "7",
number = "3",
url = "https://hdl.handle.net/21.15107/rcub_dais_13689"
}

Obradović, R., Kesić, L., Mihailović, D., Ignjatović, N.,& Uskoković, D.. (2007). Comparative Efficacy Analysis of Biomaterials and Soft Lasers in Repair of Bone Defects. in The Journal of Oral Laser Applications, 7(3), 161-166.
https://hdl.handle.net/21.15107/rcub_dais_13689

Obradović R, Kesić L, Mihailović D, Ignjatović N, Uskoković D. Comparative Efficacy Analysis of Biomaterials and Soft Lasers in Repair of Bone Defects. in The Journal of Oral Laser Applications. 2007;7(3):161-166.
https://hdl.handle.net/21.15107/rcub_dais_13689 .

Obradović, Radmila, Kesić, Ljiljana, Mihailović, Dragan, Ignjatović, Nenad, Uskoković, Dragan, "Comparative Efficacy Analysis of Biomaterials and Soft Lasers in Repair of Bone Defects" in The Journal of Oral Laser Applications, 7, no. 3 (2007):161-166,
https://hdl.handle.net/21.15107/rcub_dais_13689 .

TY  - JOUR
AU  - Živković, Radmila
AU  - Kesić, Ljiljana
AU  - Mihailović, Dragan
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2006
UR  - http://www.ncbi.nlm.nih.gov/pubmed/0354-21170602109Z
UR  - https://dais.sanu.ac.rs/123456789/3364
AB  - The efficiency of HeNe laser application in treatment of artificially caused bone defects in mandible of rats filled with biocomposite BCP/PLGA (bicalcium phosphate/polylactide-co-glycolide) was analyzed. Animals were divided in two separate groups. The first group (A) was the control one. In the second group (B) the implantation site was submitted to HeNe laser irradiation. Animals were sacrificed two, six, eight and twelve weeks after laser therapy. Histological samples were decalcified and submerged in paraffin blocks. Samples were colored with HE. Morphometrical analysis consisted of measuring area fraction, area, integral optical density, mean density and density variation. Results showed beneficial effect of laser treatment in reparation of alveolar bone after two and six weeks. After eight and twelve weeks no beneficial laser effect on biocomposite osseointegration could be noticed.
PB  - Niš : University of Niš
T2  - Facta universitatis - Series: Medicine and Biology
T1  - Investigation of HeNe laser therapy influence on BCP/PLGA osseointegration: Experimental study
SP  - 109
EP  - 113
VL  - 13
IS  - 2
UR  - https://hdl.handle.net/21.15107/rcub_dais_3364
ER  - 

@article{
author = "Živković, Radmila and Kesić, Ljiljana and Mihailović, Dragan and Ignjatović, Nenad and Uskoković, Dragan",
year = "2006",
abstract = "The efficiency of HeNe laser application in treatment of artificially caused bone defects in mandible of rats filled with biocomposite BCP/PLGA (bicalcium phosphate/polylactide-co-glycolide) was analyzed. Animals were divided in two separate groups. The first group (A) was the control one. In the second group (B) the implantation site was submitted to HeNe laser irradiation. Animals were sacrificed two, six, eight and twelve weeks after laser therapy. Histological samples were decalcified and submerged in paraffin blocks. Samples were colored with HE. Morphometrical analysis consisted of measuring area fraction, area, integral optical density, mean density and density variation. Results showed beneficial effect of laser treatment in reparation of alveolar bone after two and six weeks. After eight and twelve weeks no beneficial laser effect on biocomposite osseointegration could be noticed.",
publisher = "Niš : University of Niš",
journal = "Facta universitatis - Series: Medicine and Biology",
title = "Investigation of HeNe laser therapy influence on BCP/PLGA osseointegration: Experimental study",
pages = "109-113",
volume = "13",
number = "2",
url = "https://hdl.handle.net/21.15107/rcub_dais_3364"
}

Živković, R., Kesić, L., Mihailović, D., Ignjatović, N.,& Uskoković, D.. (2006). Investigation of HeNe laser therapy influence on BCP/PLGA osseointegration: Experimental study. in Facta universitatis - Series: Medicine and Biology
Niš : University of Niš., 13(2), 109-113.
https://hdl.handle.net/21.15107/rcub_dais_3364

Živković R, Kesić L, Mihailović D, Ignjatović N, Uskoković D. Investigation of HeNe laser therapy influence on BCP/PLGA osseointegration: Experimental study. in Facta universitatis - Series: Medicine and Biology. 2006;13(2):109-113.
https://hdl.handle.net/21.15107/rcub_dais_3364 .

Živković, Radmila, Kesić, Ljiljana, Mihailović, Dragan, Ignjatović, Nenad, Uskoković, Dragan, "Investigation of HeNe laser therapy influence on BCP/PLGA osseointegration: Experimental study" in Facta universitatis - Series: Medicine and Biology, 13, no. 2 (2006):109-113,
https://hdl.handle.net/21.15107/rcub_dais_3364 .