Kocsis, Agnes

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Optofluidic Micromachined Platform for Refractive Index Measurement

Đinović, Zoran; Tomić, Miloš; Kocsis, Agnes

(MDPI AG, 2022)

TY  - JOUR
AU  - Đinović, Zoran
AU  - Tomić, Miloš
AU  - Kocsis, Agnes
PY  - 2022
UR  - https://dais.sanu.ac.rs/123456789/13157
AB  - We present a combination of micromachined optofluidic platforms equipped with a fiber-optic sensing configuration based on a three-path Mach–Zehnder interferometer (MZI) for simultaneous measurement of the refractive index of liquids and the autocalibration in dynamic regime. The sensing principle is based on the low-coherence interferometry, characterized by a generation of Gaussian enveloped interferograms, for which the position of its maximum depends on the optical path difference (OPD) between the sensing and reference arm of the MZI. When liquid flows through the central microchannel of the optofluidic platform it crosses the light beam between the two optical fibers in the sensing arm causing the OPD change. An algorithm has been applied for the calculation of the refractive index of liquids out of the raw interference signals. We obtained a very good agreement between the experimental results and literature data of refractive indices of subjected fluids. The accuracy of refractive index measurement is approximately 1%, predominantly determined by the accuracy of reading the position of the mechanical scanner. The proposed sensor is attractive for the label-free biological, biochemical, and chemical sensing owing autocalibration and high sensitivity yet consuming a very small sample volume of 1 µL. It is capable to measure the refractive index of various liquids and/or gases simultaneously in the process.
PB  - MDPI AG
T2  - Chemosensors
T1  - Optofluidic Micromachined Platform for Refractive Index Measurement
SP  - 197
VL  - 10
IS  - 5
DO  - 10.3390/chemosensors10050197
UR  - https://hdl.handle.net/21.15107/rcub_dais_13157
ER  - 
@article{
author = "Đinović, Zoran and Tomić, Miloš and Kocsis, Agnes",
year = "2022",
abstract = "We present a combination of micromachined optofluidic platforms equipped with a fiber-optic sensing configuration based on a three-path Mach–Zehnder interferometer (MZI) for simultaneous measurement of the refractive index of liquids and the autocalibration in dynamic regime. The sensing principle is based on the low-coherence interferometry, characterized by a generation of Gaussian enveloped interferograms, for which the position of its maximum depends on the optical path difference (OPD) between the sensing and reference arm of the MZI. When liquid flows through the central microchannel of the optofluidic platform it crosses the light beam between the two optical fibers in the sensing arm causing the OPD change. An algorithm has been applied for the calculation of the refractive index of liquids out of the raw interference signals. We obtained a very good agreement between the experimental results and literature data of refractive indices of subjected fluids. The accuracy of refractive index measurement is approximately 1%, predominantly determined by the accuracy of reading the position of the mechanical scanner. The proposed sensor is attractive for the label-free biological, biochemical, and chemical sensing owing autocalibration and high sensitivity yet consuming a very small sample volume of 1 µL. It is capable to measure the refractive index of various liquids and/or gases simultaneously in the process.",
publisher = "MDPI AG",
journal = "Chemosensors",
title = "Optofluidic Micromachined Platform for Refractive Index Measurement",
pages = "197",
volume = "10",
number = "5",
doi = "10.3390/chemosensors10050197",
url = "https://hdl.handle.net/21.15107/rcub_dais_13157"
}
Đinović, Z., Tomić, M.,& Kocsis, A.. (2022). Optofluidic Micromachined Platform for Refractive Index Measurement. in Chemosensors
MDPI AG., 10(5), 197.
https://doi.org/10.3390/chemosensors10050197
https://hdl.handle.net/21.15107/rcub_dais_13157
Đinović Z, Tomić M, Kocsis A. Optofluidic Micromachined Platform for Refractive Index Measurement. in Chemosensors. 2022;10(5):197.
doi:10.3390/chemosensors10050197
https://hdl.handle.net/21.15107/rcub_dais_13157 .
Đinović, Zoran, Tomić, Miloš, Kocsis, Agnes, "Optofluidic Micromachined Platform for Refractive Index Measurement" in Chemosensors, 10, no. 5 (2022):197,
https://doi.org/10.3390/chemosensors10050197 .,
https://hdl.handle.net/21.15107/rcub_dais_13157 .