TY  - JOUR
AU  - Ajduković, Zorica
AU  - Najman, Stevo
AU  - Ðorđević, Lj.
AU  - Savić, Vojin
AU  - Mihailović, D.
AU  - Petrović, D.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2005
UR  - https://dais.sanu.ac.rs/123456789/14299
AB  - The aim of this study is to examine the reparatory ability of the synthetic biomaterial hydroxyapatite-poly-L-lactide (HAp-PLLA), the replacement of alveolar ridge, and rehabilitation of bone defects caused by osteoporosis, in an experimental group of animals. The experiments are performed on syngeneic Sprague Dawley rats. Osteoporosis is induced by glucocorticoids in rats during a 12-week period. After this, the experimental group of animals is divided into five subgroups. An artificial defect is made in the alveolar bone on the left side of the mandible. In one group of animals, the defect is left to heal by itself, while in other groups, pure HAp-PLLA or one mixed with plasma is implanted. The best results are achieved by the implantation of the HAp-PLLA composite biomaterial mixed with autologous plasma. Formation of a new mandibular bone is seen, growing intensely, leading to rapid osteogenesis.
PB  - SAGE Publications
T2  - Journal of Biomaterials Applications
T1  - Repair of Bone Tissue Affected by Osteoporosis with Hydroxyapatite-Poly-L-lactide (HAp-PLLA) with and Without Blood Plasma
SP  - 179
EP  - 190
VL  - 20
IS  - 2
DO  - 10.1177/0885328205050519
UR  - https://hdl.handle.net/21.15107/rcub_dais_14299
ER  - 

@article{
author = "Ajduković, Zorica and Najman, Stevo and Ðorđević, Lj. and Savić, Vojin and Mihailović, D. and Petrović, D. and Ignjatović, Nenad and Uskoković, Dragan",
year = "2005",
abstract = "The aim of this study is to examine the reparatory ability of the synthetic biomaterial hydroxyapatite-poly-L-lactide (HAp-PLLA), the replacement of alveolar ridge, and rehabilitation of bone defects caused by osteoporosis, in an experimental group of animals. The experiments are performed on syngeneic Sprague Dawley rats. Osteoporosis is induced by glucocorticoids in rats during a 12-week period. After this, the experimental group of animals is divided into five subgroups. An artificial defect is made in the alveolar bone on the left side of the mandible. In one group of animals, the defect is left to heal by itself, while in other groups, pure HAp-PLLA or one mixed with plasma is implanted. The best results are achieved by the implantation of the HAp-PLLA composite biomaterial mixed with autologous plasma. Formation of a new mandibular bone is seen, growing intensely, leading to rapid osteogenesis.",
publisher = "SAGE Publications",
journal = "Journal of Biomaterials Applications",
title = "Repair of Bone Tissue Affected by Osteoporosis with Hydroxyapatite-Poly-L-lactide (HAp-PLLA) with and Without Blood Plasma",
pages = "179-190",
volume = "20",
number = "2",
doi = "10.1177/0885328205050519",
url = "https://hdl.handle.net/21.15107/rcub_dais_14299"
}

Ajduković, Z., Najman, S., Ðorđević, Lj., Savić, V., Mihailović, D., Petrović, D., Ignjatović, N.,& Uskoković, D.. (2005). Repair of Bone Tissue Affected by Osteoporosis with Hydroxyapatite-Poly-L-lactide (HAp-PLLA) with and Without Blood Plasma. in Journal of Biomaterials Applications
SAGE Publications., 20(2), 179-190.
https://doi.org/10.1177/0885328205050519
https://hdl.handle.net/21.15107/rcub_dais_14299

Ajduković Z, Najman S, Ðorđević L, Savić V, Mihailović D, Petrović D, Ignjatović N, Uskoković D. Repair of Bone Tissue Affected by Osteoporosis with Hydroxyapatite-Poly-L-lactide (HAp-PLLA) with and Without Blood Plasma. in Journal of Biomaterials Applications. 2005;20(2):179-190.
doi:10.1177/0885328205050519
https://hdl.handle.net/21.15107/rcub_dais_14299 .

Ajduković, Zorica, Najman, Stevo, Ðorđević, Lj., Savić, Vojin, Mihailović, D., Petrović, D., Ignjatović, Nenad, Uskoković, Dragan, "Repair of Bone Tissue Affected by Osteoporosis with Hydroxyapatite-Poly-L-lactide (HAp-PLLA) with and Without Blood Plasma" in Journal of Biomaterials Applications, 20, no. 2 (2005):179-190,
https://doi.org/10.1177/0885328205050519 .,
https://hdl.handle.net/21.15107/rcub_dais_14299 .