Trajanović, Miroslav

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orcid::0000-0002-3325-0933
  • Trajanović, Miroslav (3)
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Author's Bibliography

Instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue: A review

Mitić, Žarko; Stolić, Aleksandra; Stojanović, Sanja; Najman, Stevo; Ignjatović, Nenad; Nikolić, Goran; Trajanović, Miroslav

(Elsevier, 2017)

TY  - JOUR
AU  - Mitić, Žarko
AU  - Stolić, Aleksandra
AU  - Stojanović, Sanja
AU  - Najman, Stevo
AU  - Ignjatović, Nenad
AU  - Nikolić, Goran
AU  - Trajanović, Miroslav
PY  - 2017
AB  - A review of recent advances in instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue is presented in this paper. In recent years, biomaterials attracted great attention primarily because of the wide range of biomedical applications. This paper focuses on the practical aspects of instrumental methods and techniques that were most often applied (X-ray methods, vibrational spectroscopy (IR and Raman), magnetic-resonance spectroscopy (NMR and ESR), mass spectrometry (MS), atomic absorption spectrometry (AAS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES), thermogravimetry (TG), differential thermal analysis (DTA) and differential scanning calorimetry (DSC), scanning electron microscopy (SEM), transmission electron microscopy (TEM)) in the structural investigation and physicochemical characterization of biomaterials and bone tissue. The application of some other physicochemical methods was also discussed. Hands-on information is provided about these valuable research tools, emphasizing practical aspects such as typical measurement conditions, their limitations and advantages, interpretation of results and practical applications.
PB  - Elsevier
T2  - Materials Science and Engineering: C
T1  - Instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue: A review
SP  - 930
EP  - 949
VL  - 79
DO  - 10.1016/j.msec.2017.05.127
ER  - 
@article{
author = "Mitić, Žarko and Stolić, Aleksandra and Stojanović, Sanja and Najman, Stevo and Ignjatović, Nenad and Nikolić, Goran and Trajanović, Miroslav",
year = "2017",
abstract = "A review of recent advances in instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue is presented in this paper. In recent years, biomaterials attracted great attention primarily because of the wide range of biomedical applications. This paper focuses on the practical aspects of instrumental methods and techniques that were most often applied (X-ray methods, vibrational spectroscopy (IR and Raman), magnetic-resonance spectroscopy (NMR and ESR), mass spectrometry (MS), atomic absorption spectrometry (AAS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES), thermogravimetry (TG), differential thermal analysis (DTA) and differential scanning calorimetry (DSC), scanning electron microscopy (SEM), transmission electron microscopy (TEM)) in the structural investigation and physicochemical characterization of biomaterials and bone tissue. The application of some other physicochemical methods was also discussed. Hands-on information is provided about these valuable research tools, emphasizing practical aspects such as typical measurement conditions, their limitations and advantages, interpretation of results and practical applications.",
publisher = "Elsevier",
journal = "Materials Science and Engineering: C",
title = "Instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue: A review",
pages = "930-949",
volume = "79",
doi = "10.1016/j.msec.2017.05.127"
}
Mitić, Ž., Stolić, A., Stojanović, S., Najman, S., Ignjatović, N., Nikolić, G.,& Trajanović, M. (2017). Instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue: A review.
Materials Science and Engineering: C
Elsevier., 79, 930-949.
https://doi.org/10.1016/j.msec.2017.05.127
Mitić Ž, Stolić A, Stojanović S, Najman S, Ignjatović N, Nikolić G, Trajanović M. Instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue: A review. Materials Science and Engineering: C. 2017;79:930-949.
doi:10.1016/j.msec.2017.05.127.
Mitić Žarko, Stolić Aleksandra, Stojanović Sanja, Najman Stevo, Ignjatović Nenad, Nikolić Goran, Trajanović Miroslav, "Instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue: A review" Materials Science and Engineering: C, 79 (2017):930-949,
https://doi.org/10.1016/j.msec.2017.05.127 .
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The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells

Lee, Bill; Gadow, Rainer; Mitić, Vojislav; Najdanović, Jelena; Najman, Stevo; Stojanović, Sanja; Živković, Jelena M.; Ignjatović, Nenad; Uskoković, Dragan; Trajanović, Miroslav

(Paris : Atlantis Press, 2017)

TY  - CONF
AU  - Najdanović, Jelena
AU  - Najman, Stevo
AU  - Stojanović, Sanja
AU  - Živković, Jelena M.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Trajanović, Miroslav
PY  - 2017
AB  - Nanomaterials are nowadays widely used in various fields of biomedicine. Before the application of biomaterials they have to be tested and fulfill some criteria. The first tests that should be performed after synthesis of some new nanomaterial with potential application in biomedical fields are biocompatibility tests. The aim of this study was to examine the influence of nanomaterial calcium phosphate/poly-(dl-lactide-co-glycolide) (CP/PLGA) on proliferation and adherence of HeLa cells in culture. For both proliferation and adherence examination, cells were treated with suspension of nanomaterial CP/PLGA at concentrations 5, 50 and 500 µg/mL, made in cell culture medium. There were four different types of treatment: (1) cells incubated with CP/PLGA for 3 days; (2) cells incubated with CP/PLGA for 6 days; (3) cells incubated first with CP/PLGA for 3 days and then for the next 3 days with medium and (4) cells incubated first with medium for 3 days and then for the next 3 days with CP/PLGA. Three days after incubation of HeLa cells with different concentrations of CP/PLGA nanoparticles’ suspension, the concentration of 5 µg/mL had mild inhibitory effect on proliferation. Increasing CP/PLGA concentration, there was stimulatory effect on cells’ proliferation. With prolonged incubation period, this dose dependence is lost. The highest adherence of HeLa cells was observed when cells were incubated with the highest examined concentration of CP/PLGA suspension, in both 3-day and 6-day incubation period. Based on the results obtained in our study, we can conclude that the effect of the suspension of nanomaterial CP/PLGA on proliferation and adherence of HeLa cells depends on the duration of incubation with the cells as well as the material concentration and type of the treatment.
PB  - Paris : Atlantis Press
C3  - Proceedings of the IV Advanced Ceramics and Applications Conference
T1  - The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells
SP  - 387
EP  - 400
DO  - 10.2991/978-94-6239-213-7_27
ER  - 
@conference{
editor = "Lee, Bill, Gadow, Rainer, Mitić, Vojislav",
author = "Najdanović, Jelena and Najman, Stevo and Stojanović, Sanja and Živković, Jelena M. and Ignjatović, Nenad and Uskoković, Dragan and Trajanović, Miroslav",
year = "2017",
abstract = "Nanomaterials are nowadays widely used in various fields of biomedicine. Before the application of biomaterials they have to be tested and fulfill some criteria. The first tests that should be performed after synthesis of some new nanomaterial with potential application in biomedical fields are biocompatibility tests. The aim of this study was to examine the influence of nanomaterial calcium phosphate/poly-(dl-lactide-co-glycolide) (CP/PLGA) on proliferation and adherence of HeLa cells in culture. For both proliferation and adherence examination, cells were treated with suspension of nanomaterial CP/PLGA at concentrations 5, 50 and 500 µg/mL, made in cell culture medium. There were four different types of treatment: (1) cells incubated with CP/PLGA for 3 days; (2) cells incubated with CP/PLGA for 6 days; (3) cells incubated first with CP/PLGA for 3 days and then for the next 3 days with medium and (4) cells incubated first with medium for 3 days and then for the next 3 days with CP/PLGA. Three days after incubation of HeLa cells with different concentrations of CP/PLGA nanoparticles’ suspension, the concentration of 5 µg/mL had mild inhibitory effect on proliferation. Increasing CP/PLGA concentration, there was stimulatory effect on cells’ proliferation. With prolonged incubation period, this dose dependence is lost. The highest adherence of HeLa cells was observed when cells were incubated with the highest examined concentration of CP/PLGA suspension, in both 3-day and 6-day incubation period. Based on the results obtained in our study, we can conclude that the effect of the suspension of nanomaterial CP/PLGA on proliferation and adherence of HeLa cells depends on the duration of incubation with the cells as well as the material concentration and type of the treatment.",
publisher = "Paris : Atlantis Press",
journal = "Proceedings of the IV Advanced Ceramics and Applications Conference",
title = "The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells",
pages = "387-400",
doi = "10.2991/978-94-6239-213-7_27"
}
Lee, B., Gadow, R., Mitić, V., Najdanović, J., Najman, S., Stojanović, S., Živković, J. M., Ignjatović, N., Uskoković, D.,& Trajanović, M. (2017). The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells.
Proceedings of the IV Advanced Ceramics and Applications Conference
Paris : Atlantis Press., 387-400.
https://doi.org/10.2991/978-94-6239-213-7_27
Lee B, Gadow R, Mitić V, Najdanović J, Najman S, Stojanović S, Živković JM, Ignjatović N, Uskoković D, Trajanović M. The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells. Proceedings of the IV Advanced Ceramics and Applications Conference. 2017;:387-400.
doi:10.2991/978-94-6239-213-7_27.
Lee Bill, Gadow Rainer, Mitić Vojislav, Najdanović Jelena, Najman Stevo, Stojanović Sanja, Živković Jelena M., Ignjatović Nenad, Uskoković Dragan, Trajanović Miroslav, "The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells" Proceedings of the IV Advanced Ceramics and Applications Conference (2017):387-400,
https://doi.org/10.2991/978-94-6239-213-7_27 .
1

Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period

Mitić, Žarko; Najman, Stevo; Cakić, Milorad; Ajduković, Zorica; Ignjatović, Nenad; Nikolić, Ružica; Nikolić, Goran; Stojanović, Sanja; Vukelić, Marija Đ.; Trajanović, Miroslav

(Elsevier, 2014)

TY  - JOUR
AU  - Mitić, Žarko
AU  - Najman, Stevo
AU  - Cakić, Milorad
AU  - Ajduković, Zorica
AU  - Ignjatović, Nenad
AU  - Nikolić, Ružica
AU  - Nikolić, Goran
AU  - Stojanović, Sanja
AU  - Vukelić, Marija Đ.
AU  - Trajanović, Miroslav
PY  - 2014
AB  - The influence of glucocorticoids on the composition and mineral/organic content of the mandible in tested animals after recovery and healing phase was investigated in this work. The results of FTIR analysis demonstrated that bone tissue composition was changed after glucocorticoid treatment. The increase of calcium, magnesium, phosphorus content and mineral part of bones was statistically significant in recovery phase and in treatment phase that included calcitonin and thymus extract. Some changes also happened in the organic part of the matrix, as indicated by intensity changes for already present IR bands and the appearance of new IR bands in the region 3500–1300 cm−1.
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period
SP  - 315
EP  - 320
VL  - 1074
DO  - 10.1016/j.molstruc.2014.06.006
ER  - 
@article{
author = "Mitić, Žarko and Najman, Stevo and Cakić, Milorad and Ajduković, Zorica and Ignjatović, Nenad and Nikolić, Ružica and Nikolić, Goran and Stojanović, Sanja and Vukelić, Marija Đ. and Trajanović, Miroslav",
year = "2014",
abstract = "The influence of glucocorticoids on the composition and mineral/organic content of the mandible in tested animals after recovery and healing phase was investigated in this work. The results of FTIR analysis demonstrated that bone tissue composition was changed after glucocorticoid treatment. The increase of calcium, magnesium, phosphorus content and mineral part of bones was statistically significant in recovery phase and in treatment phase that included calcitonin and thymus extract. Some changes also happened in the organic part of the matrix, as indicated by intensity changes for already present IR bands and the appearance of new IR bands in the region 3500–1300 cm−1.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period",
pages = "315-320",
volume = "1074",
doi = "10.1016/j.molstruc.2014.06.006"
}
Mitić, Ž., Najman, S., Cakić, M., Ajduković, Z., Ignjatović, N., Nikolić, R., Nikolić, G., Stojanović, S., Vukelić, M. Đ.,& Trajanović, M. (2014). Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period.
Journal of Molecular Structure
Elsevier., 1074, 315-320.
https://doi.org/10.1016/j.molstruc.2014.06.006
Mitić Ž, Najman S, Cakić M, Ajduković Z, Ignjatović N, Nikolić R, Nikolić G, Stojanović S, Vukelić MĐ, Trajanović M. Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period. Journal of Molecular Structure. 2014;1074:315-320.
doi:10.1016/j.molstruc.2014.06.006.
Mitić Žarko, Najman Stevo, Cakić Milorad, Ajduković Zorica, Ignjatović Nenad, Nikolić Ružica, Nikolić Goran, Stojanović Sanja, Vukelić Marija Đ., Trajanović Miroslav, "Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period" Journal of Molecular Structure, 1074 (2014):315-320,
https://doi.org/10.1016/j.molstruc.2014.06.006 .
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