TY  - JOUR
AU  - Stevanović, Magdalena
AU  - Vukomanović, Marija
AU  - Milenković, M.
AU  - Boccaccini, Aldo R.
PY  - 2022
UR  - https://dais.sanu.ac.rs/123456789/13512
AB  - Antimicrobial resistance (AMR) and infections caused by multidrug-resistant microbial pathogens represent one of the major clinical challenges responsible for high-level morbidity and mortality. They are a significant problem to the public health and the economic stability of societies all over the world. In November 2021 WHO has declared AMR as one of the top 10 global public health threats (Antimicrobial resistance (who.int)). According to CDC’s 2019 AMR Report, although declining since 2013, with 2.8 million new cases and more than 35,000 deaths each year, the number of people facing the AMR problem in United States is still too high (Antibiotic Resistance Threats in the United States, 2019 (cdc.gov)). AMR also remains the major health concern of EU with more than 670,000 new cases of infections caused by antibiotic-resistant bacterial strains and more than 33,000 deaths per year (Antimicrobial resistance surveillance in Europe 2022 - 2020 data (europa.eu)). In 2019 China recorded 39-% drop of antibiotic use in hospitalised patients compare to 2011 (Antimicrobial resistance - China (who.int)). Still, with 73,000 estimated new cases only for multi-drug resistant tuberculosis, the region remained at second position of the global highest incident rates (Antimicrobial resistance - China (who.int)). Each year a large number of people receive different kinds of implants, for example, hip or knee. However recent discoveries reveal that, either during the operative protocol or due to secondary infections, the implant’s surface could be colonized by bacteria, fungi, or both which can have serious consequences on a patient’s health. According to Annual Epidemiological Report of ECDC in 2016, post-surgical infections were identified as most common healthcare-associated infections (Surgical site infections - Annual Epidemiological Report 2016 [2014 data] (europa.eu)). In recent years it has been also recognized that microbial biofilms are ubiquitous, which has resulted in a number of studies from a biofilm perspective. Currently, great efforts are focused on the development of innovative therapeutic strategies regarding both novel drug candidates and drug delivery systems for treating microbial infections associated with implants. However, despite all these efforts as well as the urgent need, an effective and long-lasting solution to this problem is still not found. In the last decades, great attention is paid to nanostructured polymeric materials and nanocomposites because of their unique properties, which make them appropriate candidates for various applications in different medical and pharmaceutical fields. This Research Topic draws attention to the up-to-date findings regarding these issues and advanced therapeutic strategies and approaches as possible solutions.
T2  - Frontiers in Bioengineering and Biotechnology
T1  - Editorial: Antimicrobial nanostructured polymeric materials and nanocomposites, volume II
VL  - 10
DO  - 10.3389/fbioe.2022.1015485
UR  - https://hdl.handle.net/21.15107/rcub_dais_13512
ER  - 

@article{
author = "Stevanović, Magdalena and Vukomanović, Marija and Milenković, M. and Boccaccini, Aldo R.",
year = "2022",
abstract = "Antimicrobial resistance (AMR) and infections caused by multidrug-resistant microbial pathogens represent one of the major clinical challenges responsible for high-level morbidity and mortality. They are a significant problem to the public health and the economic stability of societies all over the world. In November 2021 WHO has declared AMR as one of the top 10 global public health threats (Antimicrobial resistance (who.int)). According to CDC’s 2019 AMR Report, although declining since 2013, with 2.8 million new cases and more than 35,000 deaths each year, the number of people facing the AMR problem in United States is still too high (Antibiotic Resistance Threats in the United States, 2019 (cdc.gov)). AMR also remains the major health concern of EU with more than 670,000 new cases of infections caused by antibiotic-resistant bacterial strains and more than 33,000 deaths per year (Antimicrobial resistance surveillance in Europe 2022 - 2020 data (europa.eu)). In 2019 China recorded 39-% drop of antibiotic use in hospitalised patients compare to 2011 (Antimicrobial resistance - China (who.int)). Still, with 73,000 estimated new cases only for multi-drug resistant tuberculosis, the region remained at second position of the global highest incident rates (Antimicrobial resistance - China (who.int)). Each year a large number of people receive different kinds of implants, for example, hip or knee. However recent discoveries reveal that, either during the operative protocol or due to secondary infections, the implant’s surface could be colonized by bacteria, fungi, or both which can have serious consequences on a patient’s health. According to Annual Epidemiological Report of ECDC in 2016, post-surgical infections were identified as most common healthcare-associated infections (Surgical site infections - Annual Epidemiological Report 2016 [2014 data] (europa.eu)). In recent years it has been also recognized that microbial biofilms are ubiquitous, which has resulted in a number of studies from a biofilm perspective. Currently, great efforts are focused on the development of innovative therapeutic strategies regarding both novel drug candidates and drug delivery systems for treating microbial infections associated with implants. However, despite all these efforts as well as the urgent need, an effective and long-lasting solution to this problem is still not found. In the last decades, great attention is paid to nanostructured polymeric materials and nanocomposites because of their unique properties, which make them appropriate candidates for various applications in different medical and pharmaceutical fields. This Research Topic draws attention to the up-to-date findings regarding these issues and advanced therapeutic strategies and approaches as possible solutions.",
journal = "Frontiers in Bioengineering and Biotechnology",
title = "Editorial: Antimicrobial nanostructured polymeric materials and nanocomposites, volume II",
volume = "10",
doi = "10.3389/fbioe.2022.1015485",
url = "https://hdl.handle.net/21.15107/rcub_dais_13512"
}

Stevanović, M., Vukomanović, M., Milenković, M.,& Boccaccini, A. R.. (2022). Editorial: Antimicrobial nanostructured polymeric materials and nanocomposites, volume II. in Frontiers in Bioengineering and Biotechnology, 10.
https://doi.org/10.3389/fbioe.2022.1015485
https://hdl.handle.net/21.15107/rcub_dais_13512

Stevanović M, Vukomanović M, Milenković M, Boccaccini AR. Editorial: Antimicrobial nanostructured polymeric materials and nanocomposites, volume II. in Frontiers in Bioengineering and Biotechnology. 2022;10.
doi:10.3389/fbioe.2022.1015485
https://hdl.handle.net/21.15107/rcub_dais_13512 .

Stevanović, Magdalena, Vukomanović, Marija, Milenković, M., Boccaccini, Aldo R., "Editorial: Antimicrobial nanostructured polymeric materials and nanocomposites, volume II" in Frontiers in Bioengineering and Biotechnology, 10 (2022),
https://doi.org/10.3389/fbioe.2022.1015485 .,
https://hdl.handle.net/21.15107/rcub_dais_13512 .

TY  - JOUR
AU  - Stevanović, Magdalena
AU  - Vukomanović, Marija
AU  - Milenković, Marina
AU  - Boccaccini, Aldo R.
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3948
UR  - https://dais.sanu.ac.rs/123456789/11877
AB  - Infectious diseases are a significant burden on the public health and the economic stability of societies all over the world. Drug resistance presents an ever-increasing global public health threat that involves all major microbial pathogens and antimicrobial drugs. The considerable concern regarding bacterial resistance to antimicrobial agents, bacterial adhesion, and proliferation has generated intense research in this field. Although urgently needed, an effective and long-lasting solution to this problem, i.e. microbial and especially bacterial colonization, has not yet been found. In the last decades, nanomaterials have attracted much attention because of their unique physical, chemical, and mechanical properties, due to their high surface area and size at the nanoscale. Owing to these extraordinary characteristics, nanomaterials are appropriate candidates for various applications in different fields such as medicine, pharmacy, food industry, etc. New strategies based on the use of nanomaterials such as nanoparticles, nanocapsules, nanogels, nanofibers, nanocomposites, or nanocoatings for controlling microbial virulence factors are very promising. In addition special focus recently is paid on nanostructured polymeric materials and nanocomposites with antimicrobial properties. The increasing attention within the scientific community regarding this topic can be easily assessed by searching the suitable keywords in some recognized literature databases. According to Scopus, in the last 10 years, more than 1,300 peer-reviewed documents have been published jointly containing keywords such as “nanocomposites” and “antimicrobial”. Interestingly, in the more specified search which refers to the utilization of nanostructured polymeric materials, it could be observed a similar profile i.e. growing tendency.
PB  - Frontiers Media S.A.
T2  - Frontiers in Materials
T1  - Editorial: Antimicrobial Nanostructured Polymeric Materials and Nanocomposites
VL  - 8
DO  - 10.3389/fmats.2021.748813
UR  - https://hdl.handle.net/21.15107/rcub_dais_11877
ER  - 

@article{
author = "Stevanović, Magdalena and Vukomanović, Marija and Milenković, Marina and Boccaccini, Aldo R.",
year = "2021",
abstract = "Infectious diseases are a significant burden on the public health and the economic stability of societies all over the world. Drug resistance presents an ever-increasing global public health threat that involves all major microbial pathogens and antimicrobial drugs. The considerable concern regarding bacterial resistance to antimicrobial agents, bacterial adhesion, and proliferation has generated intense research in this field. Although urgently needed, an effective and long-lasting solution to this problem, i.e. microbial and especially bacterial colonization, has not yet been found. In the last decades, nanomaterials have attracted much attention because of their unique physical, chemical, and mechanical properties, due to their high surface area and size at the nanoscale. Owing to these extraordinary characteristics, nanomaterials are appropriate candidates for various applications in different fields such as medicine, pharmacy, food industry, etc. New strategies based on the use of nanomaterials such as nanoparticles, nanocapsules, nanogels, nanofibers, nanocomposites, or nanocoatings for controlling microbial virulence factors are very promising. In addition special focus recently is paid on nanostructured polymeric materials and nanocomposites with antimicrobial properties. The increasing attention within the scientific community regarding this topic can be easily assessed by searching the suitable keywords in some recognized literature databases. According to Scopus, in the last 10 years, more than 1,300 peer-reviewed documents have been published jointly containing keywords such as “nanocomposites” and “antimicrobial”. Interestingly, in the more specified search which refers to the utilization of nanostructured polymeric materials, it could be observed a similar profile i.e. growing tendency.",
publisher = "Frontiers Media S.A.",
journal = "Frontiers in Materials",
title = "Editorial: Antimicrobial Nanostructured Polymeric Materials and Nanocomposites",
volume = "8",
doi = "10.3389/fmats.2021.748813",
url = "https://hdl.handle.net/21.15107/rcub_dais_11877"
}

Stevanović, M., Vukomanović, M., Milenković, M.,& Boccaccini, A. R.. (2021). Editorial: Antimicrobial Nanostructured Polymeric Materials and Nanocomposites. in Frontiers in Materials
Frontiers Media S.A.., 8.
https://doi.org/10.3389/fmats.2021.748813
https://hdl.handle.net/21.15107/rcub_dais_11877

Stevanović M, Vukomanović M, Milenković M, Boccaccini AR. Editorial: Antimicrobial Nanostructured Polymeric Materials and Nanocomposites. in Frontiers in Materials. 2021;8.
doi:10.3389/fmats.2021.748813
https://hdl.handle.net/21.15107/rcub_dais_11877 .

Stevanović, Magdalena, Vukomanović, Marija, Milenković, Marina, Boccaccini, Aldo R., "Editorial: Antimicrobial Nanostructured Polymeric Materials and Nanocomposites" in Frontiers in Materials, 8 (2021),
https://doi.org/10.3389/fmats.2021.748813 .,
https://hdl.handle.net/21.15107/rcub_dais_11877 .