TY  - JOUR
AU  - Pantović-Pavlović, Marijana R.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
AU  - Mirkov, Ivana I.
AU  - Kulaš, Jelena B.
AU  - Malešević, Anastasija Lj.
AU  - Pavlović, Miroslav M.
PY  - 2023
UR  - https://dais.sanu.ac.rs/123456789/14406
AB  - The aim of this work is in situ anodization/anaphoretic deposition of a nano amorphous calcium phosphate (ACP)/chitosan oligosaccharide lactate (ChOL) multifunctional hybrid coating decorated with selenium (Se) on a titanium substrate and in vivo investigation of its immunomodulatory and anti-inflammatory effect. Investigating phenomena at the implant–tissue interface of interest for controlled inflammation and immunomodulation was also the aim of the research. In our earlier research, we designed coatings based on ACP and ChOL on titanium with anticorrosive, antibacterial and biocompatible properties, while in the presented results we show that selenium addition makes this coating an immunomodulator. The immunomodulatory effect of the novel hybrid coating is characterized by the examination of the functional aspects in the tissue around the implant (in vivo): proinflammatory cytokines’ gene expression, M1 (iNOS) and M2 (Arg1) macrophages, fibrous capsule formation (TGF-β) and vascularization (VEGF). The EDS, FTIR and XRD analyses prove the formation of a ACP/ChOL/Se multifunctional hybrid coating on Ti and the presence of Se. A higher M2/M1 macrophage ratio in the ACP/ChOL/Se-coated implants compared to pure titanium implants (a higher level of Arg1 expression) is noted at all time points examined (after 7, 14 and 28 days). Lower inflammation measured by gene expression of proinflammatory cytokines IL-1β and TNF, lower expression of TGF-β in the surrounding tissue and higher IL-6 expression (solely at day 7 post-implantation) is noted in presence of the ACP/ChOL/Se-coated implants.
PB  - Basel : MDPI AG
T2  - Journal of Functional Biomaterials
T1  - Immunomodulatory Effects Mediated by Nano Amorphous Calcium Phosphate/Chitosan Oligosaccharide Lactate Coatings Decorated with Selenium on Titanium Implants
SP  - 227
VL  - 14
IS  - 4
DO  - 10.3390/jfb14040227
UR  - https://hdl.handle.net/21.15107/rcub_dais_14406
ER  - 

@article{
author = "Pantović-Pavlović, Marijana R. and Ignjatović, Nenad and Panić, Vladimir V. and Mirkov, Ivana I. and Kulaš, Jelena B. and Malešević, Anastasija Lj. and Pavlović, Miroslav M.",
year = "2023",
abstract = "The aim of this work is in situ anodization/anaphoretic deposition of a nano amorphous calcium phosphate (ACP)/chitosan oligosaccharide lactate (ChOL) multifunctional hybrid coating decorated with selenium (Se) on a titanium substrate and in vivo investigation of its immunomodulatory and anti-inflammatory effect. Investigating phenomena at the implant–tissue interface of interest for controlled inflammation and immunomodulation was also the aim of the research. In our earlier research, we designed coatings based on ACP and ChOL on titanium with anticorrosive, antibacterial and biocompatible properties, while in the presented results we show that selenium addition makes this coating an immunomodulator. The immunomodulatory effect of the novel hybrid coating is characterized by the examination of the functional aspects in the tissue around the implant (in vivo): proinflammatory cytokines’ gene expression, M1 (iNOS) and M2 (Arg1) macrophages, fibrous capsule formation (TGF-β) and vascularization (VEGF). The EDS, FTIR and XRD analyses prove the formation of a ACP/ChOL/Se multifunctional hybrid coating on Ti and the presence of Se. A higher M2/M1 macrophage ratio in the ACP/ChOL/Se-coated implants compared to pure titanium implants (a higher level of Arg1 expression) is noted at all time points examined (after 7, 14 and 28 days). Lower inflammation measured by gene expression of proinflammatory cytokines IL-1β and TNF, lower expression of TGF-β in the surrounding tissue and higher IL-6 expression (solely at day 7 post-implantation) is noted in presence of the ACP/ChOL/Se-coated implants.",
publisher = "Basel : MDPI AG",
journal = "Journal of Functional Biomaterials",
title = "Immunomodulatory Effects Mediated by Nano Amorphous Calcium Phosphate/Chitosan Oligosaccharide Lactate Coatings Decorated with Selenium on Titanium Implants",
pages = "227",
volume = "14",
number = "4",
doi = "10.3390/jfb14040227",
url = "https://hdl.handle.net/21.15107/rcub_dais_14406"
}

Pantović-Pavlović, M. R., Ignjatović, N., Panić, V. V., Mirkov, I. I., Kulaš, J. B., Malešević, A. Lj.,& Pavlović, M. M.. (2023). Immunomodulatory Effects Mediated by Nano Amorphous Calcium Phosphate/Chitosan Oligosaccharide Lactate Coatings Decorated with Selenium on Titanium Implants. in Journal of Functional Biomaterials
Basel : MDPI AG., 14(4), 227.
https://doi.org/10.3390/jfb14040227
https://hdl.handle.net/21.15107/rcub_dais_14406

Pantović-Pavlović MR, Ignjatović N, Panić VV, Mirkov II, Kulaš JB, Malešević AL, Pavlović MM. Immunomodulatory Effects Mediated by Nano Amorphous Calcium Phosphate/Chitosan Oligosaccharide Lactate Coatings Decorated with Selenium on Titanium Implants. in Journal of Functional Biomaterials. 2023;14(4):227.
doi:10.3390/jfb14040227
https://hdl.handle.net/21.15107/rcub_dais_14406 .

Pantović-Pavlović, Marijana R., Ignjatović, Nenad, Panić, Vladimir V., Mirkov, Ivana I., Kulaš, Jelena B., Malešević, Anastasija Lj., Pavlović, Miroslav M., "Immunomodulatory Effects Mediated by Nano Amorphous Calcium Phosphate/Chitosan Oligosaccharide Lactate Coatings Decorated with Selenium on Titanium Implants" in Journal of Functional Biomaterials, 14, no. 4 (2023):227,
https://doi.org/10.3390/jfb14040227 .,
https://hdl.handle.net/21.15107/rcub_dais_14406 .

TY  - CONF
AU  - Pantović-Pavlović, Marijana
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
AU  - Pavlović, Miroslav M.
PY  - 2022
UR  - https://dais.sanu.ac.rs/123456789/13652
AB  - This paper deals with the deposition of calcium phosphate and hybrid coatings based on calcium phosphate ceramics on titanium with improved properties by in situ anodization/anaphoretic deposition process. Hybrid coatings consisted of chitosan oligolactate (ChOL) and ChOL with Se as immunomodulatory oligoelement. The paper contributes to solving the problem of multi-stage pre-treatment and post-treatment of titanium and oxidized titanium surface to obtain a coating on the substrate, adhesion of the coating, antimicrobial and cytotoxic properties that occur in biomaterials, as well as reduced immune inflammatory response of the organism. The in situ method results in improved adhesion bioactive coating, increased bioactivity and biocompatibility with increased antimicrobial properties and absence of cytotoxicity. The studied biomaterials have improved properties such as: corrosion resistance, absence of toxicity to the human body and adequate strength, which enables their potential use in medicine and dentistry. The innovation is reflected in combining calcium phosphate coating synthesis and surface modification by partially incorporating a ceramic coating into the crystalline structure of the substrate. The characterization of the coatings obtained in this manner was performed by various physico-chemical, biochemical and biological methods. These characterization techniques included: FE-SEM, XRD, FTIR, cytotoxicity and in vivo testing.
PB  - Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala UISKOZAM
C3  - Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXIII YuCorr International Conference = XXIII YuCorr Međunarodna konferencija, May 16-19, 2022, Divčibare, Serbia
T1  - Novel Calcium Phosphate Coatings with Selenum on Titanium
SP  - poster-102
UR  - https://hdl.handle.net/21.15107/rcub_dais_13652
ER  - 

@conference{
author = "Pantović-Pavlović, Marijana and Ignjatović, Nenad and Panić, Vladimir V. and Pavlović, Miroslav M.",
year = "2022",
abstract = "This paper deals with the deposition of calcium phosphate and hybrid coatings based on calcium phosphate ceramics on titanium with improved properties by in situ anodization/anaphoretic deposition process. Hybrid coatings consisted of chitosan oligolactate (ChOL) and ChOL with Se as immunomodulatory oligoelement. The paper contributes to solving the problem of multi-stage pre-treatment and post-treatment of titanium and oxidized titanium surface to obtain a coating on the substrate, adhesion of the coating, antimicrobial and cytotoxic properties that occur in biomaterials, as well as reduced immune inflammatory response of the organism. The in situ method results in improved adhesion bioactive coating, increased bioactivity and biocompatibility with increased antimicrobial properties and absence of cytotoxicity. The studied biomaterials have improved properties such as: corrosion resistance, absence of toxicity to the human body and adequate strength, which enables their potential use in medicine and dentistry. The innovation is reflected in combining calcium phosphate coating synthesis and surface modification by partially incorporating a ceramic coating into the crystalline structure of the substrate. The characterization of the coatings obtained in this manner was performed by various physico-chemical, biochemical and biological methods. These characterization techniques included: FE-SEM, XRD, FTIR, cytotoxicity and in vivo testing.",
publisher = "Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala UISKOZAM",
journal = "Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXIII YuCorr International Conference = XXIII YuCorr Međunarodna konferencija, May 16-19, 2022, Divčibare, Serbia",
title = "Novel Calcium Phosphate Coatings with Selenum on Titanium",
pages = "poster-102",
url = "https://hdl.handle.net/21.15107/rcub_dais_13652"
}

Pantović-Pavlović, M., Ignjatović, N., Panić, V. V.,& Pavlović, M. M.. (2022). Novel Calcium Phosphate Coatings with Selenum on Titanium. in Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXIII YuCorr International Conference = XXIII YuCorr Međunarodna konferencija, May 16-19, 2022, Divčibare, Serbia
Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala UISKOZAM., poster-102.
https://hdl.handle.net/21.15107/rcub_dais_13652

Pantović-Pavlović M, Ignjatović N, Panić VV, Pavlović MM. Novel Calcium Phosphate Coatings with Selenum on Titanium. in Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXIII YuCorr International Conference = XXIII YuCorr Međunarodna konferencija, May 16-19, 2022, Divčibare, Serbia. 2022;:poster-102.
https://hdl.handle.net/21.15107/rcub_dais_13652 .

Pantović-Pavlović, Marijana, Ignjatović, Nenad, Panić, Vladimir V., Pavlović, Miroslav M., "Novel Calcium Phosphate Coatings with Selenum on Titanium" in Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXIII YuCorr International Conference = XXIII YuCorr Međunarodna konferencija, May 16-19, 2022, Divčibare, Serbia (2022):poster-102,
https://hdl.handle.net/21.15107/rcub_dais_13652 .

TY  - CONF
AU  - Pantović-Pavlović, Marijana
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
AU  - Pavlović, Miroslav M.
PY  - 2022
UR  - https://dais.sanu.ac.rs/123456789/13653
AB  - This paper deals with the issue of defining a new method of anodizing/anaphoretic deposition for the application of calcium phosphate and hybrid coatings based on calcium phosphate ceramics on titanium and anodized titanium coatings with improved properties. Hybrid coatings consisted of chitosan oligolactate (ChOL) and ChOL with Se as immunomodulatory oligoelement. The paper contributes to solving the problem of multi-stage pre-treatment and posttreatment of titanium and oxidized titanium surface to obtain a coating on the substrate, adhesion of the coating, antimicrobial and cytotoxic properties that occur in biomaterials, as well as reduced immune inflammatory response of the organism. It primarily deals with the creation and optimization of a new in situ anodizing/anaphoretic deposition process for obtaining multifunctional composite biomaterials. The in situ method results in improved adhesion bioactive coating, increased bioactivity and biocompatibility with increased antimicrobial properties and absence of cytotoxicity. The studied biomaterials have improved properties such as: corrosion resistance, absence of toxicity to the human body and adequate strength, which enables their potential use in medicine and dentistry. The aim of the research was to define new in situ anodizing/anaphoretic deposition process and adequate modification of process parameters for application of composite calcium phosphate coatings on titanium and its alloys, wherein innovation is reflected in combining calcium phosphate coating synthesis and surface modification by partially incorporating a ceramic coating into the crystalline structure of the substrate. The characterization of the coatings obtained in this manner was performed by various physico-chemical, biochemical and biological methods. These characterization techniques included: AFM, SEM, FE-SEM, roughness testing, XRD, FTIR, bioactivity, biocompatibility, cytotoxicity, antimicrobial activity and in vivo testing.
PB  - Split : Central and EasternEuropeanCommittee for Thermal Analysis and Calorimetry (CEEC-TAC)
C3  - Book of abstracts of the ISt Central and Eastern European Conference on Physical Chemistry and Materials Science (CEEC-PCMS1))
T1  - Advanced hybrid composite coatings based on calcium phosphate on titanium for potential biomedical applications
SP  - 44
EP  - 44
UR  - https://hdl.handle.net/21.15107/rcub_dais_13653
ER  - 

@conference{
author = "Pantović-Pavlović, Marijana and Ignjatović, Nenad and Panić, Vladimir V. and Pavlović, Miroslav M.",
year = "2022",
abstract = "This paper deals with the issue of defining a new method of anodizing/anaphoretic deposition for the application of calcium phosphate and hybrid coatings based on calcium phosphate ceramics on titanium and anodized titanium coatings with improved properties. Hybrid coatings consisted of chitosan oligolactate (ChOL) and ChOL with Se as immunomodulatory oligoelement. The paper contributes to solving the problem of multi-stage pre-treatment and posttreatment of titanium and oxidized titanium surface to obtain a coating on the substrate, adhesion of the coating, antimicrobial and cytotoxic properties that occur in biomaterials, as well as reduced immune inflammatory response of the organism. It primarily deals with the creation and optimization of a new in situ anodizing/anaphoretic deposition process for obtaining multifunctional composite biomaterials. The in situ method results in improved adhesion bioactive coating, increased bioactivity and biocompatibility with increased antimicrobial properties and absence of cytotoxicity. The studied biomaterials have improved properties such as: corrosion resistance, absence of toxicity to the human body and adequate strength, which enables their potential use in medicine and dentistry. The aim of the research was to define new in situ anodizing/anaphoretic deposition process and adequate modification of process parameters for application of composite calcium phosphate coatings on titanium and its alloys, wherein innovation is reflected in combining calcium phosphate coating synthesis and surface modification by partially incorporating a ceramic coating into the crystalline structure of the substrate. The characterization of the coatings obtained in this manner was performed by various physico-chemical, biochemical and biological methods. These characterization techniques included: AFM, SEM, FE-SEM, roughness testing, XRD, FTIR, bioactivity, biocompatibility, cytotoxicity, antimicrobial activity and in vivo testing.",
publisher = "Split : Central and EasternEuropeanCommittee for Thermal Analysis and Calorimetry (CEEC-TAC)",
journal = "Book of abstracts of the ISt Central and Eastern European Conference on Physical Chemistry and Materials Science (CEEC-PCMS1))",
title = "Advanced hybrid composite coatings based on calcium phosphate on titanium for potential biomedical applications",
pages = "44-44",
url = "https://hdl.handle.net/21.15107/rcub_dais_13653"
}

Pantović-Pavlović, M., Ignjatović, N., Panić, V. V.,& Pavlović, M. M.. (2022). Advanced hybrid composite coatings based on calcium phosphate on titanium for potential biomedical applications. in Book of abstracts of the ISt Central and Eastern European Conference on Physical Chemistry and Materials Science (CEEC-PCMS1))
Split : Central and EasternEuropeanCommittee for Thermal Analysis and Calorimetry (CEEC-TAC)., 44-44.
https://hdl.handle.net/21.15107/rcub_dais_13653

Pantović-Pavlović M, Ignjatović N, Panić VV, Pavlović MM. Advanced hybrid composite coatings based on calcium phosphate on titanium for potential biomedical applications. in Book of abstracts of the ISt Central and Eastern European Conference on Physical Chemistry and Materials Science (CEEC-PCMS1)). 2022;:44-44.
https://hdl.handle.net/21.15107/rcub_dais_13653 .

Pantović-Pavlović, Marijana, Ignjatović, Nenad, Panić, Vladimir V., Pavlović, Miroslav M., "Advanced hybrid composite coatings based on calcium phosphate on titanium for potential biomedical applications" in Book of abstracts of the ISt Central and Eastern European Conference on Physical Chemistry and Materials Science (CEEC-PCMS1)) (2022):44-44,
https://hdl.handle.net/21.15107/rcub_dais_13653 .

TY  - JOUR
AU  - Pantović-Pavlović, Marijana
AU  - Pavlović, Miroslav
AU  - Kovačina, Jovanka
AU  - Stanojević, Boris
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11738
AB  - The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 and ACP/TiO2/ /ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells exposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. These findings show that there was improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for applications in medicine and stomatology.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition
SP  - 555
EP  - 559
VL  - 86
IS  - 6
DO  - 10.2298/JSC210211024P
UR  - https://hdl.handle.net/21.15107/rcub_dais_11738
ER  - 

@article{
author = "Pantović-Pavlović, Marijana and Pavlović, Miroslav and Kovačina, Jovanka and Stanojević, Boris and Stevanović, Jasmina and Panić, Vladimir and Ignjatović, Nenad",
year = "2021",
abstract = "The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 and ACP/TiO2/ /ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells exposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. These findings show that there was improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for applications in medicine and stomatology.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition",
pages = "555-559",
volume = "86",
number = "6",
doi = "10.2298/JSC210211024P",
url = "https://hdl.handle.net/21.15107/rcub_dais_11738"
}

Pantović-Pavlović, M., Pavlović, M., Kovačina, J., Stanojević, B., Stevanović, J., Panić, V.,& Ignjatović, N.. (2021). Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(6), 555-559.
https://doi.org/10.2298/JSC210211024P
https://hdl.handle.net/21.15107/rcub_dais_11738

Pantović-Pavlović M, Pavlović M, Kovačina J, Stanojević B, Stevanović J, Panić V, Ignjatović N. Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition. in Journal of the Serbian Chemical Society. 2021;86(6):555-559.
doi:10.2298/JSC210211024P
https://hdl.handle.net/21.15107/rcub_dais_11738 .

Pantović-Pavlović, Marijana, Pavlović, Miroslav, Kovačina, Jovanka, Stanojević, Boris, Stevanović, Jasmina, Panić, Vladimir, Ignjatović, Nenad, "Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition" in Journal of the Serbian Chemical Society, 86, no. 6 (2021):555-559,
https://doi.org/10.2298/JSC210211024P .,
https://hdl.handle.net/21.15107/rcub_dais_11738 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Stanojević, Boris P.
AU  - Pavlović, Miroslav M.
AU  - Mihailović, Marija D.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11739
AB  - The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.
PB  - American Chemical Society (ACS)
T2  - ACS Biomaterials Science & Engineering
T1  - Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties
SP  - 3088
EP  - 3102
VL  - 7
IS  - 7
DO  - 10.1021/acsbiomaterials.1c00035
UR  - https://hdl.handle.net/21.15107/rcub_dais_11739
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Stanojević, Boris P. and Pavlović, Miroslav M. and Mihailović, Marija D. and Stevanović, Jasmina and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.",
publisher = "American Chemical Society (ACS)",
journal = "ACS Biomaterials Science & Engineering",
title = "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties",
pages = "3088-3102",
volume = "7",
number = "7",
doi = "10.1021/acsbiomaterials.1c00035",
url = "https://hdl.handle.net/21.15107/rcub_dais_11739"
}

Pantović Pavlović, M. R., Stanojević, B. P., Pavlović, M. M., Mihailović, M. D., Stevanović, J., Panić, V. V.,& Ignjatović, N.. (2021). Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering
American Chemical Society (ACS)., 7(7), 3088-3102.
https://doi.org/10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11739

Pantović Pavlović MR, Stanojević BP, Pavlović MM, Mihailović MD, Stevanović J, Panić VV, Ignjatović N. Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering. 2021;7(7):3088-3102.
doi:10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11739 .

Pantović Pavlović, Marijana R., Stanojević, Boris P., Pavlović, Miroslav M., Mihailović, Marija D., Stevanović, Jasmina, Panić, Vladimir V., Ignjatović, Nenad, "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties" in ACS Biomaterials Science & Engineering, 7, no. 7 (2021):3088-3102,
https://doi.org/10.1021/acsbiomaterials.1c00035 .,
https://hdl.handle.net/21.15107/rcub_dais_11739 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Stanojević, Boris P.
AU  - Pavlović, Miroslav M.
AU  - Mihailović, Marija D.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11784
AB  - The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.
PB  - American Chemical Society (ACS)
T2  - ACS Biomaterials Science & Engineering
T1  - Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties
SP  - 3088
EP  - 3102
VL  - 7
IS  - 7
DO  - 10.1021/acsbiomaterials.1c00035
UR  - https://hdl.handle.net/21.15107/rcub_dais_11784
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Stanojević, Boris P. and Pavlović, Miroslav M. and Mihailović, Marija D. and Stevanović, Jasmina and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. The coatings were obtained by new single-step in situ anodization of the substrate to generate TiO2 and the anaphoretic electrodeposition process of ACP and ChOL. The obtained coatings were around 300 ± 15 μm thick and consisted of two phases, namely, TiO2 and hybrid composite phases. Both ACP/TiO2 and ACP + ChOL/TiO2 have improved corrosion stability, whereas the ACP + ChOL/TiO2 coating showed better corrosion stability. It was shown that at the very start of the deposition process, the formation of the ChOL/TiO2 layer takes place predominantly, which is followed by the inclusion of ChOL into ACP with simultaneous growth of TiO2. This deposition mechanism resulted in the formation of strongly bonded uniform stable coating with high corrosion resistance. In vitro bioactivity was investigated by immersion of the samples in simulated body fluid (SBF). There is in-bone-like apatite formation on both ACP/TiO2 and ACP + ChOL/TiO2 surfaces upon immersion into SBF, which was proven by X-ray diffraction and Fourier transform infrared spectroscopy. While ACP/TiO2 shows no antibacterial activity, ACP + ChOL/TiO2 samples exhibited three- to fourfold decreases in the number of Staphylococcus aureus and Pseudomonas aeruginosa, respectively, after 420 min. The probable mechanism is binding ChOL with the bacterial cell wall, inhibiting its growth, altering the permeability of the cell membrane, and leading to bacterial death.",
publisher = "American Chemical Society (ACS)",
journal = "ACS Biomaterials Science & Engineering",
title = "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties",
pages = "3088-3102",
volume = "7",
number = "7",
doi = "10.1021/acsbiomaterials.1c00035",
url = "https://hdl.handle.net/21.15107/rcub_dais_11784"
}

Pantović Pavlović, M. R., Stanojević, B. P., Pavlović, M. M., Mihailović, M. D., Stevanović, J., Panić, V. V.,& Ignjatović, N.. (2021). Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering
American Chemical Society (ACS)., 7(7), 3088-3102.
https://doi.org/10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11784

Pantović Pavlović MR, Stanojević BP, Pavlović MM, Mihailović MD, Stevanović J, Panić VV, Ignjatović N. Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties. in ACS Biomaterials Science & Engineering. 2021;7(7):3088-3102.
doi:10.1021/acsbiomaterials.1c00035
https://hdl.handle.net/21.15107/rcub_dais_11784 .

Pantović Pavlović, Marijana R., Stanojević, Boris P., Pavlović, Miroslav M., Mihailović, Marija D., Stevanović, Jasmina, Panić, Vladimir V., Ignjatović, Nenad, "Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties" in ACS Biomaterials Science & Engineering, 7, no. 7 (2021):3088-3102,
https://doi.org/10.1021/acsbiomaterials.1c00035 .,
https://hdl.handle.net/21.15107/rcub_dais_11784 .

TY  - DATA
AU  - Pantović-Pavlović, Marijana
AU  - Stanojević, Boris
AU  - Pavlović, Miroslav M.
AU  - Mihailović, Marija D.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/11740
AB  - The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. Supplementary information: The ANOVA results of antimicrobial activity on S. aureus are shown in Table S1 and the ANOVA results of antimicrobial activity on P. aeruginosa are shown in Table S2. The analysis showed significant difference at the 5% level of confidence.
PB  - American Chemical Society (ACS)
T2  - ACS Biomaterials Science & Engineering
T1  - Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035
VL  - 7
IS  - 7
UR  - https://hdl.handle.net/21.15107/rcub_dais_11740
ER  - 

@misc{
author = "Pantović-Pavlović, Marijana and Stanojević, Boris and Pavlović, Miroslav M. and Mihailović, Marija D. and Stevanović, Jasmina and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "The aim of this work was to investigate corrosion resistivity, bioactivity, and antibacterial activity of novel nano-amorphous calcium phosphate (ACP) potentially multifunctional composite coatings with and without chitosan oligosaccharide lactate (ChOL), ACP + ChOL/TiO2 and ACP/TiO2 ACP + ChOL/TiO2, respectively, on the titanium substrate. Supplementary information: The ANOVA results of antimicrobial activity on S. aureus are shown in Table S1 and the ANOVA results of antimicrobial activity on P. aeruginosa are shown in Table S2. The analysis showed significant difference at the 5% level of confidence.",
publisher = "American Chemical Society (ACS)",
journal = "ACS Biomaterials Science & Engineering",
title = "Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035",
volume = "7",
number = "7",
url = "https://hdl.handle.net/21.15107/rcub_dais_11740"
}

Pantović-Pavlović, M., Stanojević, B., Pavlović, M. M., Mihailović, M. D., Stevanović, J., Panić, V. V.,& Ignjatović, N.. (2021). Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035. in ACS Biomaterials Science & Engineering
American Chemical Society (ACS)., 7(7).
https://hdl.handle.net/21.15107/rcub_dais_11740

Pantović-Pavlović M, Stanojević B, Pavlović MM, Mihailović MD, Stevanović J, Panić VV, Ignjatović N. Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035. in ACS Biomaterials Science & Engineering. 2021;7(7).
https://hdl.handle.net/21.15107/rcub_dais_11740 .

Pantović-Pavlović, Marijana, Stanojević, Boris, Pavlović, Miroslav M., Mihailović, Marija D., Stevanović, Jasmina, Panić, Vladimir V., Ignjatović, Nenad, "Supplementary information for the article: Pantović Pavlović, Marijana R., Boris P. Stanojević, Miroslav M. Pavlović, Marija D. Mihailović, Jasmina S. Stevanović, Vladimir V. Panić, and Nenad L. Ignjatović. 2021. “Anodizing/Anaphoretic Electrodeposition of Nano-Calcium Phosphate/Chitosan Lactate Multifunctional Coatings on Titanium with Advanced Corrosion Resistance, Bioactivity, and Antibacterial Properties.” ACS Biomaterials Science & Engineering 7 (7): 3088–3102. https://doi.org/10.1021/acsbiomaterials.1c00035" in ACS Biomaterials Science & Engineering, 7, no. 7 (2021),
https://hdl.handle.net/21.15107/rcub_dais_11740 .

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2021
UR  - https://dais.sanu.ac.rs/123456789/12363
AB  - Kalcijum fosfati (CP), među kojima su amorfni kalcijum fosfat (ACP) i hidroksiapatit (HAp), zajedno sa slojevima Ti i TiO2, pronašli su ogromnu primenu u preventivnoj i regenerativnoj medicini zbog svoje odlične biokompatibilnosti, netoksičnih svojstava i sposobnosti da učestvuju u metaboličnim procesima organizama. U ovom radu je prikazana citotoksičnost multifunkcionalnih i hibridnih kompozitnih prevlaka amorfnog kalcijum fosfata (ACP) i hitozan laktata (ChOL) na ćelijskoj liniji humanih fibroblasta pluća MRC-5. ACP/TiO2 i ACP/TiO2/ChOL prevlake su taložene novim procesom in situ anodizacije/anaforetske depozicije pri konstantnom naponu od 60 V tokom 180 s na 25 ° C. Testovi citotoksičnosti pokazali su da nije bilo značajnog smanjenja preživljavanja zdravih ćelija MRC-5 u kompozitnim uzorcima Ti i ACP/TiO2, dok je došlo do povećanja broja viabilnih ćelija u uzorku ACP/TiO2/ChOL. Pokazano je poboljšanje ćelijske proliferacije, diferencijacije i viabilnosti ćelija. Uzorak koji sadrži ACP/TiO2/ChOL prevlaku pokazao je negativnu citotoksičnost u DET i u MTT testovima. Zabeležen je veći oporavak humanih ćelija fibroblasta pluća MRC-5 u poređenju sa kontrolnim uzorkom posle 48 h oporavka. Iz ovih rezultata može se zaključiti da multifunkcionalna kompozitna prevlaka ACP/TiO2/ChOL nije samo necitotoksična, već prisustvo ChOL-a u prevlaci poboljšava ćelijsku proliferaciju, diferencijaciju i viabilnost ćelija. Na osnovu dobijenih rezultata može se zaključiti da oba kompozitna materijala koji su korišćeni u studijama nisu citotoksični za korišćene ćelijske linije, te da 5 tež.% ChOL-a ima pozitivan efekat na netoksičnost materijala. Na osnovu prikazanih rezultata u ovom radu i prethodnih objavljenih rezultata fizičko-hemijskih i bioaktivnih svojstava kompozitnog materijala ACP/TiO2/ChOL, može se zaključiti da bi dalji razvoj, kao i potencijalne pretkliničke studije bili u velikoj meri opravdani.
AB  - Calcium phosphates (CP), amongst which amorphous calcium phosphate (ACP) and hydroxyapatite (HAp), along with Ti and TiO2 layers, have found vast applications in preventive and regenerative medicine due to their excellent biocompatibility, nontoxic properties and ability to participate in the normal metabolism of organisms. In this paper cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line is presented. ACP/TiO2 and ACP/TiO2/ChOL are deposited by coatings new in situ anodization/anaphoretic deposition process at constant voltage of 60 V for 180 s at 25 °C. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells in the Ti and ACP/TiO2 composite samples, while there was an increase in the number of viable cells in the ACP/TiO2/ChOL sample. There is improved cell proliferation, differentiation and cell viability in the later. Sample containing ACP/TiO2/ChOL coating showed negative cytotoxicity in both DET and MTT tests. Greater recovery of MRC-5 human lung fibroblasts cells was observed compared to the control sample after 48 h of recovery. From these results, it can be concluded that not only the ACP/TiO2/ChOL multifunctional composite coating is non-cytotoxic, but the presence of ChOL in the coating improves cell proliferation, differentiation and cell viability. Based on the obtained results, it can be concluded that both composite materials used in the studies are non-cytotoxic to the cell lines used, and that 5 wt.% of ChOL has a positive effect on the non-toxicity of the material. Based on presented results in this paper and previous published results of the physicochemical and bioactive properties of the ACP/TiO2/ChOL composite material, it can be concluded that further development as well as potential preclinical studies would be largely justified.
PB  - Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala UISKOZAM
C3  - Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXII YuCorr International Conference = XXI YuCorr [Jugoslovenska korozija] Međunarodna konferencija, September 13-16, 2021, Tara Mountain, Serbia
T1  - Upoređivanje bioaktivnosti, citotoksičnosti, antimikrobnih i korozivnih svojstava keramičkih prevlaka sa i bez polimera na titanu
T1  - Comparison of bioactivity, cytotoxicity, antimicrobial and corrosive behavior of ceramic coatings with and without polymer on titanium
SP  - INVITED-21
UR  - https://hdl.handle.net/21.15107/rcub_dais_12363
ER  - 

@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2021",
abstract = "Kalcijum fosfati (CP), među kojima su amorfni kalcijum fosfat (ACP) i hidroksiapatit (HAp), zajedno sa slojevima Ti i TiO2, pronašli su ogromnu primenu u preventivnoj i regenerativnoj medicini zbog svoje odlične biokompatibilnosti, netoksičnih svojstava i sposobnosti da učestvuju u metaboličnim procesima organizama. U ovom radu je prikazana citotoksičnost multifunkcionalnih i hibridnih kompozitnih prevlaka amorfnog kalcijum fosfata (ACP) i hitozan laktata (ChOL) na ćelijskoj liniji humanih fibroblasta pluća MRC-5. ACP/TiO2 i ACP/TiO2/ChOL prevlake su taložene novim procesom in situ anodizacije/anaforetske depozicije pri konstantnom naponu od 60 V tokom 180 s na 25 ° C. Testovi citotoksičnosti pokazali su da nije bilo značajnog smanjenja preživljavanja zdravih ćelija MRC-5 u kompozitnim uzorcima Ti i ACP/TiO2, dok je došlo do povećanja broja viabilnih ćelija u uzorku ACP/TiO2/ChOL. Pokazano je poboljšanje ćelijske proliferacije, diferencijacije i viabilnosti ćelija. Uzorak koji sadrži ACP/TiO2/ChOL prevlaku pokazao je negativnu citotoksičnost u DET i u MTT testovima. Zabeležen je veći oporavak humanih ćelija fibroblasta pluća MRC-5 u poređenju sa kontrolnim uzorkom posle 48 h oporavka. Iz ovih rezultata može se zaključiti da multifunkcionalna kompozitna prevlaka ACP/TiO2/ChOL nije samo necitotoksična, već prisustvo ChOL-a u prevlaci poboljšava ćelijsku proliferaciju, diferencijaciju i viabilnost ćelija. Na osnovu dobijenih rezultata može se zaključiti da oba kompozitna materijala koji su korišćeni u studijama nisu citotoksični za korišćene ćelijske linije, te da 5 tež.% ChOL-a ima pozitivan efekat na netoksičnost materijala. Na osnovu prikazanih rezultata u ovom radu i prethodnih objavljenih rezultata fizičko-hemijskih i bioaktivnih svojstava kompozitnog materijala ACP/TiO2/ChOL, može se zaključiti da bi dalji razvoj, kao i potencijalne pretkliničke studije bili u velikoj meri opravdani., Calcium phosphates (CP), amongst which amorphous calcium phosphate (ACP) and hydroxyapatite (HAp), along with Ti and TiO2 layers, have found vast applications in preventive and regenerative medicine due to their excellent biocompatibility, nontoxic properties and ability to participate in the normal metabolism of organisms. In this paper cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line is presented. ACP/TiO2 and ACP/TiO2/ChOL are deposited by coatings new in situ anodization/anaphoretic deposition process at constant voltage of 60 V for 180 s at 25 °C. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells in the Ti and ACP/TiO2 composite samples, while there was an increase in the number of viable cells in the ACP/TiO2/ChOL sample. There is improved cell proliferation, differentiation and cell viability in the later. Sample containing ACP/TiO2/ChOL coating showed negative cytotoxicity in both DET and MTT tests. Greater recovery of MRC-5 human lung fibroblasts cells was observed compared to the control sample after 48 h of recovery. From these results, it can be concluded that not only the ACP/TiO2/ChOL multifunctional composite coating is non-cytotoxic, but the presence of ChOL in the coating improves cell proliferation, differentiation and cell viability. Based on the obtained results, it can be concluded that both composite materials used in the studies are non-cytotoxic to the cell lines used, and that 5 wt.% of ChOL has a positive effect on the non-toxicity of the material. Based on presented results in this paper and previous published results of the physicochemical and bioactive properties of the ACP/TiO2/ChOL composite material, it can be concluded that further development as well as potential preclinical studies would be largely justified.",
publisher = "Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala UISKOZAM",
journal = "Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXII YuCorr International Conference = XXI YuCorr [Jugoslovenska korozija] Međunarodna konferencija, September 13-16, 2021, Tara Mountain, Serbia",
title = "Upoređivanje bioaktivnosti, citotoksičnosti, antimikrobnih i korozivnih svojstava keramičkih prevlaka sa i bez polimera na titanu, Comparison of bioactivity, cytotoxicity, antimicrobial and corrosive behavior of ceramic coatings with and without polymer on titanium",
pages = "INVITED-21",
url = "https://hdl.handle.net/21.15107/rcub_dais_12363"
}

Pantović Pavlović, M. R., Pavlović, M. M., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2021). Upoređivanje bioaktivnosti, citotoksičnosti, antimikrobnih i korozivnih svojstava keramičkih prevlaka sa i bez polimera na titanu. in Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXII YuCorr International Conference = XXI YuCorr [Jugoslovenska korozija] Međunarodna konferencija, September 13-16, 2021, Tara Mountain, Serbia
Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala UISKOZAM., INVITED-21.
https://hdl.handle.net/21.15107/rcub_dais_12363

Pantović Pavlović MR, Pavlović MM, Stevanović JS, Panić VV, Ignjatović N. Upoređivanje bioaktivnosti, citotoksičnosti, antimikrobnih i korozivnih svojstava keramičkih prevlaka sa i bez polimera na titanu. in Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXII YuCorr International Conference = XXI YuCorr [Jugoslovenska korozija] Međunarodna konferencija, September 13-16, 2021, Tara Mountain, Serbia. 2021;:INVITED-21.
https://hdl.handle.net/21.15107/rcub_dais_12363 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Upoređivanje bioaktivnosti, citotoksičnosti, antimikrobnih i korozivnih svojstava keramičkih prevlaka sa i bez polimera na titanu" in Meeting point of the science and practice in the fields of corrosion, materials and environmental protection : proceedings = Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine : knjiga radova / XXII YuCorr International Conference = XXI YuCorr [Jugoslovenska korozija] Međunarodna konferencija, September 13-16, 2021, Tara Mountain, Serbia (2021):INVITED-21,
https://hdl.handle.net/21.15107/rcub_dais_12363 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2020
UR  - http://www.sciencedirect.com/science/article/pii/S0167577X19317537
UR  - https://dais.sanu.ac.rs/123456789/6915
AB  - In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.
PB  - Elsevier
T2  - Materials Letters
T1  - Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate
SP  - 127121
VL  - 261
DO  - 10.1016/j.matlet.2019.127121
UR  - https://hdl.handle.net/21.15107/rcub_dais_6915
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2020",
abstract = "In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.",
publisher = "Elsevier",
journal = "Materials Letters",
title = "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate",
pages = "127121",
volume = "261",
doi = "10.1016/j.matlet.2019.127121",
url = "https://hdl.handle.net/21.15107/rcub_dais_6915"
}

Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2020). Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters
Elsevier., 261, 127121.
https://doi.org/10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6915

Pantović Pavlović MR, Pavlović MM, Eraković S, Stevanović JS, Panić VV, Ignjatović N. Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters. 2020;261:127121.
doi:10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6915 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate" in Materials Letters, 261 (2020):127121,
https://doi.org/10.1016/j.matlet.2019.127121 .,
https://hdl.handle.net/21.15107/rcub_dais_6915 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2020
UR  - http://www.sciencedirect.com/science/article/pii/S0167577X19317537
UR  - https://dais.sanu.ac.rs/123456789/6914
AB  - In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.
PB  - Elsevier
T2  - Materials Letters
T1  - Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate
SP  - 127121
VL  - 261
DO  - 10.1016/j.matlet.2019.127121
UR  - https://hdl.handle.net/21.15107/rcub_dais_6914
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2020",
abstract = "In this paper novel in situ one-step simultaneous anaphoretic deposition process of amorphous calcium phosphate (ACP) and titanium oxide (TiOx) with and without chitosan oligosaccharide lactate (ChOL) on titanium substrate was performed. The coatings were investigated by SEM, XRD and FTIR techniques, whereas roughness and adhesion were measured. It was shown that novel process occurs, with improved coatings adhesion and excellent coverage of the surface. At 90 V the surface is smoother, and there is possibility for crystallization of the components at prolonged deposition times.",
publisher = "Elsevier",
journal = "Materials Letters",
title = "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate",
pages = "127121",
volume = "261",
doi = "10.1016/j.matlet.2019.127121",
url = "https://hdl.handle.net/21.15107/rcub_dais_6914"
}

Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2020). Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters
Elsevier., 261, 127121.
https://doi.org/10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6914

Pantović Pavlović MR, Pavlović MM, Eraković S, Stevanović JS, Panić VV, Ignjatović N. Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate. in Materials Letters. 2020;261:127121.
doi:10.1016/j.matlet.2019.127121
https://hdl.handle.net/21.15107/rcub_dais_6914 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Simultaneous anodization/anaphoretic electrodeposition synthesis of nano calcium phosphate/titanium oxide composite coatings assisted with chitosan oligosaccharide lactate" in Materials Letters, 261 (2020):127121,
https://doi.org/10.1016/j.matlet.2019.127121 .,
https://hdl.handle.net/21.15107/rcub_dais_6914 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Eraković, Sanja G.
AU  - Pavlović, Miroslav M.
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - http://www.sciencedirect.com/science/article/pii/S0257897218313148
UR  - https://dais.sanu.ac.rs/123456789/4556
AB  - In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.
PB  - Elsevier
T2  - Surface and Coatings Technology
T1  - Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium
SP  - 688
EP  - 694
VL  - 358
DO  - 10.1016/j.surfcoat.2018.12.003
UR  - https://hdl.handle.net/21.15107/rcub_dais_4556
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Eraković, Sanja G. and Pavlović, Miroslav M. and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.",
publisher = "Elsevier",
journal = "Surface and Coatings Technology",
title = "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium",
pages = "688-694",
volume = "358",
doi = "10.1016/j.surfcoat.2018.12.003",
url = "https://hdl.handle.net/21.15107/rcub_dais_4556"
}

Pantović Pavlović, M. R., Eraković, S. G., Pavlović, M. M., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology
Elsevier., 358, 688-694.
https://doi.org/10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4556

Pantović Pavlović MR, Eraković SG, Pavlović MM, Stevanović JS, Panić VV, Ignjatović N. Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology. 2019;358:688-694.
doi:10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4556 .

Pantović Pavlović, Marijana R., Eraković, Sanja G., Pavlović, Miroslav M., Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium" in Surface and Coatings Technology, 358 (2019):688-694,
https://doi.org/10.1016/j.surfcoat.2018.12.003 .,
https://hdl.handle.net/21.15107/rcub_dais_4556 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Eraković, Sanja G.
AU  - Pavlović, Miroslav M.
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - http://www.sciencedirect.com/science/article/pii/S0257897218313148
UR  - https://dais.sanu.ac.rs/123456789/4555
AB  - In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.
PB  - Elsevier
T2  - Surface and Coatings Technology
T2  - Surface and Coatings TechnologySurface and Coatings Technology
T1  - Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium
SP  - 688
EP  - 694
VL  - 358
DO  - 10.1016/j.surfcoat.2018.12.003
UR  - https://hdl.handle.net/21.15107/rcub_dais_4555
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Eraković, Sanja G. and Pavlović, Miroslav M. and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.",
publisher = "Elsevier",
journal = "Surface and Coatings Technology, Surface and Coatings TechnologySurface and Coatings Technology",
title = "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium",
pages = "688-694",
volume = "358",
doi = "10.1016/j.surfcoat.2018.12.003",
url = "https://hdl.handle.net/21.15107/rcub_dais_4555"
}

Pantović Pavlović, M. R., Eraković, S. G., Pavlović, M. M., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology
Elsevier., 358, 688-694.
https://doi.org/10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4555

Pantović Pavlović MR, Eraković SG, Pavlović MM, Stevanović JS, Panić VV, Ignjatović N. Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium. in Surface and Coatings Technology. 2019;358:688-694.
doi:10.1016/j.surfcoat.2018.12.003
https://hdl.handle.net/21.15107/rcub_dais_4555 .

Pantović Pavlović, Marijana R., Eraković, Sanja G., Pavlović, Miroslav M., Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Anaphoretical/oxidative approach to the in-situ synthesis of adherent hydroxyapatite/titanium oxide composite coatings on titanium" in Surface and Coatings Technology, 358 (2019):688-694,
https://doi.org/10.1016/j.surfcoat.2018.12.003 .,
https://hdl.handle.net/21.15107/rcub_dais_4555 .

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja G.
AU  - Veselinović, Ljiljana
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6226
AB  - In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.
PB  - Zvornik : Faculty of Technology
C3  - Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019
T1  - Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition
SP  - 630
EP  - 635
UR  - https://hdl.handle.net/21.15107/rcub_dais_6226
ER  - 

@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja G. and Veselinović, Ljiljana and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "In-situ synthesis of HAp/TiO2 coating on titanium was performed via anaphoretic deposition of HAp and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. HAp on anodized titanium was prepared at constant voltage of 60 V and deposition time of 45 s, which provided uniform and adherent HAp/TiO2 composite coating on Ti. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to reduced brittleness and improved adhesion.",
publisher = "Zvornik : Faculty of Technology",
journal = "Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019",
title = "Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition",
pages = "630-635",
url = "https://hdl.handle.net/21.15107/rcub_dais_6226"
}

Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S. G., Veselinović, L., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition. in Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019
Zvornik : Faculty of Technology., 630-635.
https://hdl.handle.net/21.15107/rcub_dais_6226

Pantović Pavlović MR, Pavlović MM, Eraković SG, Veselinović L, Stevanović JS, Panić VV, Ignjatović N. Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition. in Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019. 2019;:630-635.
https://hdl.handle.net/21.15107/rcub_dais_6226 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja G., Veselinović, Ljiljana, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Novel in-situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium by simultaneous anodization/anaphoretic electrodeposition" in Proceedings / VI International Congress "Engineering, Ecology and Materials in the Processing Industry", Jahorina, March 11-13, 2019 (2019):630-635,
https://hdl.handle.net/21.15107/rcub_dais_6226 .

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Eraković, Sanja G.
AU  - Pavlović, Miroslav M.
AU  - Veselinović, Ljiljana
AU  - Stevanović, Jasmina S.
AU  - Panić, Vladimir V.
AU  - Ignjatović, Nenad
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6244
AB  - The medical devices based on titanium and its alloys are widely used in the repair and replacement of a degraded or inhibited func-tion of locomotor system [1]. Ti and its alloys exhibit high mechanical strength, good workability, resistant to corrosion and low cost. Although, they are widely used as orthopedic and dental implants their inability to interact with living tissue will inhibit their biological fixation and osseoin-tegration [2]. Therefore, to improve the hard-tissue compatibility of Ti various sur-face treatments have been developed for the inorganic coating formation [3]. The hyd-roxyapatite (HAp, Ca10(PO4)6(OH)2) with superior osteogenic activity is a competitive approach to make novel coatings for titanium implants applications. HAp is a calcium phosphate very similar to the inorganic part of the human bone and hard tissues both in morphology and compo-sition. Herein, in-situ synthesis of HAp/TiO2 coating on titanium was performed via ana-phoretic deposition of HAp and simulta-neous anodization of Ti to produce highly adherent and strengthened composite coating. It can be seen that morphology of Ti substrate of anHAP/TiO2 coating is of tubular shape, and tube formation occurs mainly due to competing processes of anodization and electrophoretic deposition of HAp. anHAp/TiO2 coating does not need sintering process, and simultaneous Ti anodization and HAp deposition occur, where HAp crystals incorporate in the anodized Ti surface. From the presented results it can be concluded that novel suggested process of in situ simultaneous anHAp/TiO2 deposition with Ti surface anodization gives much better results that cathaphoretic deposition regarding adhesion.
PB  - International Association of Physical Chemists
C3  - Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
T1  - Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis
SP  - 120
EP  - 120
UR  - https://hdl.handle.net/21.15107/rcub_dais_6244
ER  - 

@conference{
author = "Pantović Pavlović, Marijana R. and Eraković, Sanja G. and Pavlović, Miroslav M. and Veselinović, Ljiljana and Stevanović, Jasmina S. and Panić, Vladimir V. and Ignjatović, Nenad",
year = "2019",
abstract = "The medical devices based on titanium and its alloys are widely used in the repair and replacement of a degraded or inhibited func-tion of locomotor system [1]. Ti and its alloys exhibit high mechanical strength, good workability, resistant to corrosion and low cost. Although, they are widely used as orthopedic and dental implants their inability to interact with living tissue will inhibit their biological fixation and osseoin-tegration [2]. Therefore, to improve the hard-tissue compatibility of Ti various sur-face treatments have been developed for the inorganic coating formation [3]. The hyd-roxyapatite (HAp, Ca10(PO4)6(OH)2) with superior osteogenic activity is a competitive approach to make novel coatings for titanium implants applications. HAp is a calcium phosphate very similar to the inorganic part of the human bone and hard tissues both in morphology and compo-sition. Herein, in-situ synthesis of HAp/TiO2 coating on titanium was performed via ana-phoretic deposition of HAp and simulta-neous anodization of Ti to produce highly adherent and strengthened composite coating. It can be seen that morphology of Ti substrate of anHAP/TiO2 coating is of tubular shape, and tube formation occurs mainly due to competing processes of anodization and electrophoretic deposition of HAp. anHAp/TiO2 coating does not need sintering process, and simultaneous Ti anodization and HAp deposition occur, where HAp crystals incorporate in the anodized Ti surface. From the presented results it can be concluded that novel suggested process of in situ simultaneous anHAp/TiO2 deposition with Ti surface anodization gives much better results that cathaphoretic deposition regarding adhesion.",
publisher = "International Association of Physical Chemists",
journal = "Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019",
title = "Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis",
pages = "120-120",
url = "https://hdl.handle.net/21.15107/rcub_dais_6244"
}

Pantović Pavlović, M. R., Eraković, S. G., Pavlović, M. M., Veselinović, L., Stevanović, J. S., Panić, V. V.,& Ignjatović, N.. (2019). Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
International Association of Physical Chemists., 120-120.
https://hdl.handle.net/21.15107/rcub_dais_6244

Pantović Pavlović MR, Eraković SG, Pavlović MM, Veselinović L, Stevanović JS, Panić VV, Ignjatović N. Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019. 2019;:120-120.
https://hdl.handle.net/21.15107/rcub_dais_6244 .

Pantović Pavlović, Marijana R., Eraković, Sanja G., Pavlović, Miroslav M., Veselinović, Ljiljana, Stevanović, Jasmina S., Panić, Vladimir V., Ignjatović, Nenad, "Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis" in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019 (2019):120-120,
https://hdl.handle.net/21.15107/rcub_dais_6244 .

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja G.
AU  - Stevanović, Jasmina S.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/7008
AB  - In-situ synthesis of hydroxyapatite/titanium oxide (HAp/TiO2) coating on titanium was performed via anaphoretic deposition of hydroxyapatite (HAp) and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and anodization of titanium was examined, as well as influence of same process parameters on adhesion strength and compactness of composite HAp/TiO2 coatings was investigated. Prior to novel in situ method of synthesis of hydroxyapatite/titanium oxide composite coatings by simultaneous anodization/anaphoretic electrodeposition described in this manuscript, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all anodization processes had constant quantity of electric charge. Characterization of titanium samples, prepared from grade 6 Ti, and having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness.
A chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of calcium oxide (obtained by calcination of CaCO3 for 5 h at 1000 °C in air) and phosphoric acid. A stoichiometric amount of the calcium oxide was stirred in distilled water and phosphoric acid was added drop wise to the suspension in order to obtain hydroxyapatite powder, Ca10(PO4)6(OH)2.
Two types of HAp coatings were prepared, in order to compare the adhesion, morphology and consistency of the HAp and composite HAp/TiO2 on Ti, namely cathaphoretic and anaphoretic coatings, respectively [1,2]. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. Adhesion was investigated by ASTM D 3359 – 97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to improved adhesion.
PB  - Padova : Societa chimica italiana, Divisione di Elettrochimica
C3  - Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy
T1  - Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion
SP  - 124
EP  - 124
UR  - https://hdl.handle.net/21.15107/rcub_dais_7008
ER  - 

@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja G. and Stevanović, Jasmina S. and Ignjatović, Nenad and Panić, Vladimir V.",
year = "2019",
abstract = "In-situ synthesis of hydroxyapatite/titanium oxide (HAp/TiO2) coating on titanium was performed via anaphoretic deposition of hydroxyapatite (HAp) and simultaneous anodization of Ti to produce highly adherent and strengthened composite coating. The influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and anodization of titanium was examined, as well as influence of same process parameters on adhesion strength and compactness of composite HAp/TiO2 coatings was investigated. Prior to novel in situ method of synthesis of hydroxyapatite/titanium oxide composite coatings by simultaneous anodization/anaphoretic electrodeposition described in this manuscript, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all anodization processes had constant quantity of electric charge. Characterization of titanium samples, prepared from grade 6 Ti, and having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness.
A chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of calcium oxide (obtained by calcination of CaCO3 for 5 h at 1000 °C in air) and phosphoric acid. A stoichiometric amount of the calcium oxide was stirred in distilled water and phosphoric acid was added drop wise to the suspension in order to obtain hydroxyapatite powder, Ca10(PO4)6(OH)2.
Two types of HAp coatings were prepared, in order to compare the adhesion, morphology and consistency of the HAp and composite HAp/TiO2 on Ti, namely cathaphoretic and anaphoretic coatings, respectively [1,2]. The prepared coatings were characterized by field emission scanning electron microscopy, X-ray diffraction and electron dispersive spectroscopy. Adhesion was investigated by ASTM D 3359 – 97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. Since smaller size of HAp crystals within highly porous coating structures is of improved binding ability to various biomolecules, our coating is expected to be of excellent coverage and compactness. The obtained coating can be good candidate for bone implants due to improved adhesion.",
publisher = "Padova : Societa chimica italiana, Divisione di Elettrochimica",
journal = "Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy",
title = "Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion",
pages = "124-124",
url = "https://hdl.handle.net/21.15107/rcub_dais_7008"
}

Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S. G., Stevanović, J. S., Ignjatović, N.,& Panić, V. V.. (2019). Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion. in Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy
Padova : Societa chimica italiana, Divisione di Elettrochimica., 124-124.
https://hdl.handle.net/21.15107/rcub_dais_7008

Pantović Pavlović MR, Pavlović MM, Eraković SG, Stevanović JS, Ignjatović N, Panić VV. Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion. in Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy. 2019;:124-124.
https://hdl.handle.net/21.15107/rcub_dais_7008 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja G., Stevanović, Jasmina S., Ignjatović, Nenad, Panić, Vladimir V., "Influence of process parameters of simultaneous anodization/anaphoretic electrodeposition synthesis of hydroxyapatite/titanium oxide composite coatings on adhesion" in Program and the Book of Abstracts / Giornate dell’Elettrochimica Italiana GEI 2019, 8-12 September 2019 Padova, Italy (2019):124-124,
https://hdl.handle.net/21.15107/rcub_dais_7008 .

TY  - CONF
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja G.
AU  - Barudžija, Tanja
AU  - Stevanović, Jasmina S.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
PY  - 2019
UR  - https://dais.sanu.ac.rs/123456789/6983
AB  - Titanium substrates were electrochemically treated by novel in-situ synthesis method to produce anaphoretic hydroxyapatite/titanium oxide (HAp/TiO2) coating. This synthesis method was performed via anaphoretic deposition of hydroxyapatite and simultaneous anodization of Ti in order to produce highly adherent and strengthened composite coating, where the influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and adhesion strength of composite HAp/TiO2 coatings was examined. In situ synthesis was performed in different solutions containing different concentrations of NaOH, HAp and ethanol at different values of time and constant voltage. The effects of anodizing voltage on the morphology and bioactivity of the HAp coating and on the bonding strength between the HAp coating and the anodized substrates were investigated. A modified chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of stoichiometric amount of calcium oxide and phosphoric acid. Prior to novel in situ synthesis of HAp/TiO2 composite coatings, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all experiments had constant quantity of electric charge. Results indicated that highly ordered amorphous TiO2 surface is formed on the Ti substrate after anodic oxidation. Characterization of titanium samples having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness. The prepared coatings were characterized by FE-SEM, XRD and EDS. Adhesion was investigated by ASTM D 3359–97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. The results of simulated body fluid immersing experiments suggest that obtained HAp coating exhibits promising bioactivity. The obtained coating can be good candidate for bone implants due to improved adhesion.
PB  - Novi Sad : Faculty of Technology
C3  - Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad
T1  - In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition
SP  - 131
EP  - 131
UR  - https://hdl.handle.net/21.15107/rcub_dais_6983
ER  - 

@conference{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja G. and Barudžija, Tanja and Stevanović, Jasmina S. and Ignjatović, Nenad and Panić, Vladimir V.",
year = "2019",
abstract = "Titanium substrates were electrochemically treated by novel in-situ synthesis method to produce anaphoretic hydroxyapatite/titanium oxide (HAp/TiO2) coating. This synthesis method was performed via anaphoretic deposition of hydroxyapatite and simultaneous anodization of Ti in order to produce highly adherent and strengthened composite coating, where the influence of electric potential, time, electrolyte concentration and pH value of the anodization process on titanium surface roughness and adhesion strength of composite HAp/TiO2 coatings was examined. In situ synthesis was performed in different solutions containing different concentrations of NaOH, HAp and ethanol at different values of time and constant voltage. The effects of anodizing voltage on the morphology and bioactivity of the HAp coating and on the bonding strength between the HAp coating and the anodized substrates were investigated. A modified chemical precipitation method was used to prepare hydroxyapatite powder by the reaction of stoichiometric amount of calcium oxide and phosphoric acid. Prior to novel in situ synthesis of HAp/TiO2 composite coatings, optimization of anodization process of titanium was performed. Anodization was executed under different electric potentials and different distances of counter electrodes from working electrodes, but all experiments had constant quantity of electric charge. Results indicated that highly ordered amorphous TiO2 surface is formed on the Ti substrate after anodic oxidation. Characterization of titanium samples having rectangular contact surfaces of 10×10×0.89 mm included SEM/EDS analyses, X-ray diffraction analyses, AFM surface topography, morphology and roughness analyses and linear measurements of roughness. The prepared coatings were characterized by FE-SEM, XRD and EDS. Adhesion was investigated by ASTM D 3359–97 Test method B. Uniform and adherent HAp/TiO2 composite coating on Ti was obtained. The results of simulated body fluid immersing experiments suggest that obtained HAp coating exhibits promising bioactivity. The obtained coating can be good candidate for bone implants due to improved adhesion.",
publisher = "Novi Sad : Faculty of Technology",
journal = "Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad",
title = "In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition",
pages = "131-131",
url = "https://hdl.handle.net/21.15107/rcub_dais_6983"
}

Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S. G., Barudžija, T., Stevanović, J. S., Ignjatović, N.,& Panić, V. V.. (2019). In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition. in Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad
Novi Sad : Faculty of Technology., 131-131.
https://hdl.handle.net/21.15107/rcub_dais_6983

Pantović Pavlović MR, Pavlović MM, Eraković SG, Barudžija T, Stevanović JS, Ignjatović N, Panić VV. In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition. in Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad. 2019;:131-131.
https://hdl.handle.net/21.15107/rcub_dais_6983 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja G., Barudžija, Tanja, Stevanović, Jasmina S., Ignjatović, Nenad, Panić, Vladimir V., "In situ synthesis and characterization of hydroxyapatite/titanium oxide coatings derived by anodization and anaphoretic deposition" in Programme and book of abstracts / 13th Conference for Young Scientists in Ceramics (CYSC-2017), October 16-19, 2019, Novi Sad (2019):131-131,
https://hdl.handle.net/21.15107/rcub_dais_6983 .

TY  - JOUR
AU  - Pantović Pavlović, Marijana R.
AU  - Pavlović, Miroslav M.
AU  - Eraković, Sanja
AU  - Barudžija, Tanja
AU  - Stevanović, Jasmina S.
AU  - Ignjatović, Nenad
AU  - Panić, Vladimir V.
PY  - 2019
UR  - https://www.shd-pub.org.rs/index.php/JSCS/article/view/8524
UR  - https://dais.sanu.ac.rs/123456789/6916
AB  - The optimization of the anodization process of Ti substrate for in situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium substrate was accomplished. The anodization was performed under 30, 60 and 90 V cell voltage, and the morphology of treated surface, as well as linear and surface roughness, were analysed by field emission-scanning electron micro­scopy, atomic force microscopy and roughness tester. It was shown by linear and surface roughness analyses that titanium anodized under 60 V has the high­est roughness, whereas at 90 V the flattening of the surface occurs. As the highest surface roughness results emerged at 60 V, the novel process of com­po­site anHAp/TiO2 coating synthesis, which comprises simultaneous processes of TiO2 formation and HAp deposition, as well as HAp impregnation within TiO2 surface layer, was performed at this voltage. Ti substrate surface was completely covered by composite coating, with no visible cracks. The adhesion quantified according to ASTM D3359-02 standard is considerably improved with respect to the coatings obtained by cathaphoretic processes, with no need of subsequent sintering.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite
SP  - 1305
EP  - 1318
VL  - 84
IS  - 11
DO  - 10.2298/JSC190730105P
UR  - https://hdl.handle.net/21.15107/rcub_dais_6916
ER  - 

@article{
author = "Pantović Pavlović, Marijana R. and Pavlović, Miroslav M. and Eraković, Sanja and Barudžija, Tanja and Stevanović, Jasmina S. and Ignjatović, Nenad and Panić, Vladimir V.",
year = "2019",
abstract = "The optimization of the anodization process of Ti substrate for in situ synthesis of hydroxyapatite/titanium oxide composite coatings on titanium substrate was accomplished. The anodization was performed under 30, 60 and 90 V cell voltage, and the morphology of treated surface, as well as linear and surface roughness, were analysed by field emission-scanning electron micro­scopy, atomic force microscopy and roughness tester. It was shown by linear and surface roughness analyses that titanium anodized under 60 V has the high­est roughness, whereas at 90 V the flattening of the surface occurs. As the highest surface roughness results emerged at 60 V, the novel process of com­po­site anHAp/TiO2 coating synthesis, which comprises simultaneous processes of TiO2 formation and HAp deposition, as well as HAp impregnation within TiO2 surface layer, was performed at this voltage. Ti substrate surface was completely covered by composite coating, with no visible cracks. The adhesion quantified according to ASTM D3359-02 standard is considerably improved with respect to the coatings obtained by cathaphoretic processes, with no need of subsequent sintering.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite",
pages = "1305-1318",
volume = "84",
number = "11",
doi = "10.2298/JSC190730105P",
url = "https://hdl.handle.net/21.15107/rcub_dais_6916"
}

Pantović Pavlović, M. R., Pavlović, M. M., Eraković, S., Barudžija, T., Stevanović, J. S., Ignjatović, N.,& Panić, V. V.. (2019). Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 84(11), 1305-1318.
https://doi.org/10.2298/JSC190730105P
https://hdl.handle.net/21.15107/rcub_dais_6916

Pantović Pavlović MR, Pavlović MM, Eraković S, Barudžija T, Stevanović JS, Ignjatović N, Panić VV. Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite. in Journal of the Serbian Chemical Society. 2019;84(11):1305-1318.
doi:10.2298/JSC190730105P
https://hdl.handle.net/21.15107/rcub_dais_6916 .

Pantović Pavlović, Marijana R., Pavlović, Miroslav M., Eraković, Sanja, Barudžija, Tanja, Stevanović, Jasmina S., Ignjatović, Nenad, Panić, Vladimir V., "Relationship between the properties of an interlayer formed by in situ Ti anodization and anaphoretically deposited hydroxyapatite" in Journal of the Serbian Chemical Society, 84, no. 11 (2019):1305-1318,
https://doi.org/10.2298/JSC190730105P .,
https://hdl.handle.net/21.15107/rcub_dais_6916 .