TY  - JOUR
AU  - Radan, Milica
AU  - Ćujić Nikolić, Nada
AU  - Kuzmanović Nedeljković, Snežana
AU  - Mutavski, Zorana
AU  - Krgović, Nemanja
AU  - Stević, Tatjana
AU  - Marković, Smilja
AU  - Jovanović, Aleksandra
AU  - Živković, Jelena
AU  - Šavikin, Katarina
PY  - 2024
UR  - https://dais.sanu.ac.rs/123456789/16332
AB  - Recovering the bioactive components from pomegranate peel (PP) in the fruit-processing industry has attracted great attention in terms of minimizing the waste burden, as well as providing a new source of a multitude of functional compounds. The present study aimed to develop a feasible microencapsulation process of PP extract by using pectin and a pectin/2-hydroxypropyl-β-cyclodextrin (HP-β-CD) blend as coating materials. Microsized powders obtained by a spray drying technique were examined in terms of technological characteristics, exhibiting high powder yield and desirable moisture content, flowability, and cohesive properties. Assuming that the interactions with the used biopolymers occur on the surface hydrophobic domain, their presence significantly improved the thermal stability of the microencapsulated powders up to 200 °C. The health-promoting effects of PP have been associated with its high content in ellagitannins, particularly punicalagin. The obtained PP powders exhibited strong antioxidant and hypoglycemic potential, while an antimicrobial assay revealed their potent activity against Gram-positive bacteria. Additionally, an in vitro release study suggested that the used biopolymers can modify the release of target bioactive compounds, thus establishing a basis for developing an oral-controlled release system. Altogether, biowaste valorization from PP by the production of effective multifunctional microsized powders represents a sustainable way to obtain novel nutraceuticals and/or pharmaceuticals.
PB  - Basel : MDPI AG
T2  - Plants
T1  - Multifunctional Pomegranate Peel Microparticles with Health-Promoting Effects for the Sustainable Development of Novel Nutraceuticals and Pharmaceuticals
SP  - 281
VL  - 13
IS  - 2
DO  - 10.3390/plants13020281
UR  - https://hdl.handle.net/21.15107/rcub_dais_16332
ER  - 

@article{
author = "Radan, Milica and Ćujić Nikolić, Nada and Kuzmanović Nedeljković, Snežana and Mutavski, Zorana and Krgović, Nemanja and Stević, Tatjana and Marković, Smilja and Jovanović, Aleksandra and Živković, Jelena and Šavikin, Katarina",
year = "2024",
abstract = "Recovering the bioactive components from pomegranate peel (PP) in the fruit-processing industry has attracted great attention in terms of minimizing the waste burden, as well as providing a new source of a multitude of functional compounds. The present study aimed to develop a feasible microencapsulation process of PP extract by using pectin and a pectin/2-hydroxypropyl-β-cyclodextrin (HP-β-CD) blend as coating materials. Microsized powders obtained by a spray drying technique were examined in terms of technological characteristics, exhibiting high powder yield and desirable moisture content, flowability, and cohesive properties. Assuming that the interactions with the used biopolymers occur on the surface hydrophobic domain, their presence significantly improved the thermal stability of the microencapsulated powders up to 200 °C. The health-promoting effects of PP have been associated with its high content in ellagitannins, particularly punicalagin. The obtained PP powders exhibited strong antioxidant and hypoglycemic potential, while an antimicrobial assay revealed their potent activity against Gram-positive bacteria. Additionally, an in vitro release study suggested that the used biopolymers can modify the release of target bioactive compounds, thus establishing a basis for developing an oral-controlled release system. Altogether, biowaste valorization from PP by the production of effective multifunctional microsized powders represents a sustainable way to obtain novel nutraceuticals and/or pharmaceuticals.",
publisher = "Basel : MDPI AG",
journal = "Plants",
title = "Multifunctional Pomegranate Peel Microparticles with Health-Promoting Effects for the Sustainable Development of Novel Nutraceuticals and Pharmaceuticals",
pages = "281",
volume = "13",
number = "2",
doi = "10.3390/plants13020281",
url = "https://hdl.handle.net/21.15107/rcub_dais_16332"
}

Radan, M., Ćujić Nikolić, N., Kuzmanović Nedeljković, S., Mutavski, Z., Krgović, N., Stević, T., Marković, S., Jovanović, A., Živković, J.,& Šavikin, K.. (2024). Multifunctional Pomegranate Peel Microparticles with Health-Promoting Effects for the Sustainable Development of Novel Nutraceuticals and Pharmaceuticals. in Plants
Basel : MDPI AG., 13(2), 281.
https://doi.org/10.3390/plants13020281
https://hdl.handle.net/21.15107/rcub_dais_16332

Radan M, Ćujić Nikolić N, Kuzmanović Nedeljković S, Mutavski Z, Krgović N, Stević T, Marković S, Jovanović A, Živković J, Šavikin K. Multifunctional Pomegranate Peel Microparticles with Health-Promoting Effects for the Sustainable Development of Novel Nutraceuticals and Pharmaceuticals. in Plants. 2024;13(2):281.
doi:10.3390/plants13020281
https://hdl.handle.net/21.15107/rcub_dais_16332 .

Radan, Milica, Ćujić Nikolić, Nada, Kuzmanović Nedeljković, Snežana, Mutavski, Zorana, Krgović, Nemanja, Stević, Tatjana, Marković, Smilja, Jovanović, Aleksandra, Živković, Jelena, Šavikin, Katarina, "Multifunctional Pomegranate Peel Microparticles with Health-Promoting Effects for the Sustainable Development of Novel Nutraceuticals and Pharmaceuticals" in Plants, 13, no. 2 (2024):281,
https://doi.org/10.3390/plants13020281 .,
https://hdl.handle.net/21.15107/rcub_dais_16332 .

TY  - CONF
AU  - Ganić, Tea
AU  - Cvetković, Stefana
AU  - Vuletić, Stefana
AU  - Stević, Tatjana
AU  - Stevanović, Magdalena
AU  - Tomić, Nina
AU  - Nikolić, Biljana
AU  - Mitić Ćulafić, Dragana
PY  - 2023
UR  - https://dais.sanu.ac.rs/123456789/16246
AB  - Cimet je jedna od najpoznatijih aromatičnih biljaka, koje je najčešće korišćena kao začin. Prepoznat je kao potencijalni terapeutik u narodnoj medicini, zbog čega se dugo koristi za lečenje različitih infekcija. Etarska ulja su sekundarni metaboliti koje sintetišu aromatične biljke. Za etarsko ulje cimeta (CEO) su definisane različite biološke aktivnosti, međutim fizičkohemijske karakteristike ulja su slaba rastvorljivost u vodi i laka isparljivost, što ograničava njihovu primenu. Iz tog razloga, formulacija emulzija etarskih ulja predstavlja dobro rešenje za prevazilaženje problema njihove primene. Iako se CEO smatra bezbednim za upotrebu, rezultati istraživanja variraju, ukazujući na neophodnost daljih toksikoloških istraživanja. Cilj ovog rada je bila komparativna analiza biološke aktivnosti i in vitro toksičnosti CEO i njegove emulzije (EM). Antioksidativni potencijal je ispitivan DPPH testom. MTT test je primenjen u cilju procene citotoksičnog efekta CEO i EM na fibroblastima pluća fetusa (MRC–5). Na istoj ćelijskoj liniji, ispitivan je nivo oštećenja molekula DNK, primenom alkalnog komet testa. Na osnovu rezltata DPPH testa, IC50 vrednost za CEO je bila 320 μg/mL, dok je za EM bila 54 μg/mL. Na ćelijskoj liniji MRC–5, IC50 vrednosti dobijene MTT testom su iznosile 0,13 mg/mL za CEO i 0,025 mg/mL za EM. CEO i EM nisu pokazali genotoksični potencijal. Uzimajući sve prethodno navedeno u obzir, CEO i EM, kao jaki antioksidanti koji pokazuju odsustvo genotoksičnosti i slabu citotoksičnost.
AB  - Cinnamon is among most popular aromatic plants, generally used as a spice. Over the centuries it was recognized as a potential therapeutic for different kind of infections. Essential oils are aromatic plants’ secondary metabolites. Cinnamon essential oil (CEO) possess many favorable biological activities, but its physicochemical properties, as an oil, are poor solubility in water and high volatility, which limits its application. For that reason, preparation of essential oils’ emulsions seems to be solution to overcome applicability problems. Even though CEO is one of the oils recognized as safe to be used, the results from different studies vary, indicating necessity to further study its toxicological properties. The aim of this study was to comparatively analyze CEO and its emulsion (EM) biological activity and in vitro toxicity. Antioxidative potential was investigated using DPPH assay. The MTT assay was applied for the estimation of cytotoxic effects of CEO and EM on fetal fibroblasts (MRC-5) cell line. On the same cell line, level of DNA damage was evaluated, using alkaline comet assay. According to the DPPH assay results, IC50 value for CEO was 320 μg/mL, for EM was 54 μg/mL. On MRC-5 cell line, IC50 values were 0.13 mg/mL for CEO and 0.025 mg/mL for EM. Both CEO and EM didn’t exhibit potential to induce DNA damage. Taking all above mention into account, as strong antioxidants without genotoxicity and with weak cytotoxicity, CEO and EM could be considered as good candidates for further investigation of biological activities and potential for human use.
PB  - Beograd : Udruženje toksikologa Srbije
C3  - 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference : Present and future of toxicology: challenges and opportunities : 10-12 May 2023 Belgrade : abstract book
T1  - Procena antioksidativnog, citotoksičnog i genotoksičnog efekta etarskog ulja cimeta i njegove emulzije
T1  - Evaluation of antioxidative, cytotoxic and genotoxic effect of cinnamon essential oil and its emulsion
SP  - 152
EP  - 153
UR  - https://hdl.handle.net/21.15107/rcub_dais_16246
ER  - 

@conference{
author = "Ganić, Tea and Cvetković, Stefana and Vuletić, Stefana and Stević, Tatjana and Stevanović, Magdalena and Tomić, Nina and Nikolić, Biljana and Mitić Ćulafić, Dragana",
year = "2023",
abstract = "Cimet je jedna od najpoznatijih aromatičnih biljaka, koje je najčešće korišćena kao začin. Prepoznat je kao potencijalni terapeutik u narodnoj medicini, zbog čega se dugo koristi za lečenje različitih infekcija. Etarska ulja su sekundarni metaboliti koje sintetišu aromatične biljke. Za etarsko ulje cimeta (CEO) su definisane različite biološke aktivnosti, međutim fizičkohemijske karakteristike ulja su slaba rastvorljivost u vodi i laka isparljivost, što ograničava njihovu primenu. Iz tog razloga, formulacija emulzija etarskih ulja predstavlja dobro rešenje za prevazilaženje problema njihove primene. Iako se CEO smatra bezbednim za upotrebu, rezultati istraživanja variraju, ukazujući na neophodnost daljih toksikoloških istraživanja. Cilj ovog rada je bila komparativna analiza biološke aktivnosti i in vitro toksičnosti CEO i njegove emulzije (EM). Antioksidativni potencijal je ispitivan DPPH testom. MTT test je primenjen u cilju procene citotoksičnog efekta CEO i EM na fibroblastima pluća fetusa (MRC–5). Na istoj ćelijskoj liniji, ispitivan je nivo oštećenja molekula DNK, primenom alkalnog komet testa. Na osnovu rezltata DPPH testa, IC50 vrednost za CEO je bila 320 μg/mL, dok je za EM bila 54 μg/mL. Na ćelijskoj liniji MRC–5, IC50 vrednosti dobijene MTT testom su iznosile 0,13 mg/mL za CEO i 0,025 mg/mL za EM. CEO i EM nisu pokazali genotoksični potencijal. Uzimajući sve prethodno navedeno u obzir, CEO i EM, kao jaki antioksidanti koji pokazuju odsustvo genotoksičnosti i slabu citotoksičnost., Cinnamon is among most popular aromatic plants, generally used as a spice. Over the centuries it was recognized as a potential therapeutic for different kind of infections. Essential oils are aromatic plants’ secondary metabolites. Cinnamon essential oil (CEO) possess many favorable biological activities, but its physicochemical properties, as an oil, are poor solubility in water and high volatility, which limits its application. For that reason, preparation of essential oils’ emulsions seems to be solution to overcome applicability problems. Even though CEO is one of the oils recognized as safe to be used, the results from different studies vary, indicating necessity to further study its toxicological properties. The aim of this study was to comparatively analyze CEO and its emulsion (EM) biological activity and in vitro toxicity. Antioxidative potential was investigated using DPPH assay. The MTT assay was applied for the estimation of cytotoxic effects of CEO and EM on fetal fibroblasts (MRC-5) cell line. On the same cell line, level of DNA damage was evaluated, using alkaline comet assay. According to the DPPH assay results, IC50 value for CEO was 320 μg/mL, for EM was 54 μg/mL. On MRC-5 cell line, IC50 values were 0.13 mg/mL for CEO and 0.025 mg/mL for EM. Both CEO and EM didn’t exhibit potential to induce DNA damage. Taking all above mention into account, as strong antioxidants without genotoxicity and with weak cytotoxicity, CEO and EM could be considered as good candidates for further investigation of biological activities and potential for human use.",
publisher = "Beograd : Udruženje toksikologa Srbije",
journal = "13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference : Present and future of toxicology: challenges and opportunities : 10-12 May 2023 Belgrade : abstract book",
title = "Procena antioksidativnog, citotoksičnog i genotoksičnog efekta etarskog ulja cimeta i njegove emulzije, Evaluation of antioxidative, cytotoxic and genotoxic effect of cinnamon essential oil and its emulsion",
pages = "152-153",
url = "https://hdl.handle.net/21.15107/rcub_dais_16246"
}

Ganić, T., Cvetković, S., Vuletić, S., Stević, T., Stevanović, M., Tomić, N., Nikolić, B.,& Mitić Ćulafić, D.. (2023). Procena antioksidativnog, citotoksičnog i genotoksičnog efekta etarskog ulja cimeta i njegove emulzije. in 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference : Present and future of toxicology: challenges and opportunities : 10-12 May 2023 Belgrade : abstract book
Beograd : Udruženje toksikologa Srbije., 152-153.
https://hdl.handle.net/21.15107/rcub_dais_16246

Ganić T, Cvetković S, Vuletić S, Stević T, Stevanović M, Tomić N, Nikolić B, Mitić Ćulafić D. Procena antioksidativnog, citotoksičnog i genotoksičnog efekta etarskog ulja cimeta i njegove emulzije. in 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference : Present and future of toxicology: challenges and opportunities : 10-12 May 2023 Belgrade : abstract book. 2023;:152-153.
https://hdl.handle.net/21.15107/rcub_dais_16246 .

Ganić, Tea, Cvetković, Stefana, Vuletić, Stefana, Stević, Tatjana, Stevanović, Magdalena, Tomić, Nina, Nikolić, Biljana, Mitić Ćulafić, Dragana, "Procena antioksidativnog, citotoksičnog i genotoksičnog efekta etarskog ulja cimeta i njegove emulzije" in 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference : Present and future of toxicology: challenges and opportunities : 10-12 May 2023 Belgrade : abstract book (2023):152-153,
https://hdl.handle.net/21.15107/rcub_dais_16246 .

TY  - JOUR
AU  - Kuzmanović Nedeljković, Snežana
AU  - Radan, Milica
AU  - Ćujić Nikolić, Nada
AU  - Mutavski, Zorana
AU  - Krgović, Nemanja
AU  - Marković, Smilja
AU  - Stević, Tatjana
AU  - Živković, Jelena
AU  - Šavikin, Katarina
PY  - 2023
UR  - https://dais.sanu.ac.rs/123456789/16163
AB  - The aim of the research was to develop microencapsulated powders of bilberry and chokeberry extracts via the spray drying technique. Two biopolymers, pectin alone and in combination with HP-β-CD, were used to preserve the antioxidant, hypoglycemic, photoprotective, and antimicrobial bioactivity of the berry leaf extracts. Moreover, the formed powders were characterized in terms of technological, chemical, and several biological properties. The obtained micro-sized powders (mean average particle diameter from 3.83 to 5.94 µm) demonstrated a process yield of up to 73%. The added biopolymers improved the flowability and cohesive properties of the powders and increased their thermal stability to 170 °C. The total content of polyphenolics in the powders ranged from 323.35 to 367.76 mg GAE/g DW for bilberry and from 186.85 to 227.59 mg GAE/g DW for chokeberry powders; meanwhile, chlorogenic acid was the predominant compound in powders. All samples showed stronger α-glucosidase inhibitory activity (IC50 values ranged from 5.00 to 19.59 µg/mL) compared with the reference standard. The study confirmed that spray drying is a suitable method for the preservation of the polyphenolic-rich extracts, while the addition of carriers has a positive effect on the improvement of microencapsulated powders’ properties.
PB  - Basel : MDPI
T2  - Plants
T1  - Microencapsulated Bilberry and Chokeberry Leaf Extracts with Potential Health Benefits
SP  - 3979
VL  - 12
IS  - 23
DO  - 10.3390/plants12233979
UR  - https://hdl.handle.net/21.15107/rcub_dais_16163
ER  - 

@article{
author = "Kuzmanović Nedeljković, Snežana and Radan, Milica and Ćujić Nikolić, Nada and Mutavski, Zorana and Krgović, Nemanja and Marković, Smilja and Stević, Tatjana and Živković, Jelena and Šavikin, Katarina",
year = "2023",
abstract = "The aim of the research was to develop microencapsulated powders of bilberry and chokeberry extracts via the spray drying technique. Two biopolymers, pectin alone and in combination with HP-β-CD, were used to preserve the antioxidant, hypoglycemic, photoprotective, and antimicrobial bioactivity of the berry leaf extracts. Moreover, the formed powders were characterized in terms of technological, chemical, and several biological properties. The obtained micro-sized powders (mean average particle diameter from 3.83 to 5.94 µm) demonstrated a process yield of up to 73%. The added biopolymers improved the flowability and cohesive properties of the powders and increased their thermal stability to 170 °C. The total content of polyphenolics in the powders ranged from 323.35 to 367.76 mg GAE/g DW for bilberry and from 186.85 to 227.59 mg GAE/g DW for chokeberry powders; meanwhile, chlorogenic acid was the predominant compound in powders. All samples showed stronger α-glucosidase inhibitory activity (IC50 values ranged from 5.00 to 19.59 µg/mL) compared with the reference standard. The study confirmed that spray drying is a suitable method for the preservation of the polyphenolic-rich extracts, while the addition of carriers has a positive effect on the improvement of microencapsulated powders’ properties.",
publisher = "Basel : MDPI",
journal = "Plants",
title = "Microencapsulated Bilberry and Chokeberry Leaf Extracts with Potential Health Benefits",
pages = "3979",
volume = "12",
number = "23",
doi = "10.3390/plants12233979",
url = "https://hdl.handle.net/21.15107/rcub_dais_16163"
}

Kuzmanović Nedeljković, S., Radan, M., Ćujić Nikolić, N., Mutavski, Z., Krgović, N., Marković, S., Stević, T., Živković, J.,& Šavikin, K.. (2023). Microencapsulated Bilberry and Chokeberry Leaf Extracts with Potential Health Benefits. in Plants
Basel : MDPI., 12(23), 3979.
https://doi.org/10.3390/plants12233979
https://hdl.handle.net/21.15107/rcub_dais_16163

Kuzmanović Nedeljković S, Radan M, Ćujić Nikolić N, Mutavski Z, Krgović N, Marković S, Stević T, Živković J, Šavikin K. Microencapsulated Bilberry and Chokeberry Leaf Extracts with Potential Health Benefits. in Plants. 2023;12(23):3979.
doi:10.3390/plants12233979
https://hdl.handle.net/21.15107/rcub_dais_16163 .

Kuzmanović Nedeljković, Snežana, Radan, Milica, Ćujić Nikolić, Nada, Mutavski, Zorana, Krgović, Nemanja, Marković, Smilja, Stević, Tatjana, Živković, Jelena, Šavikin, Katarina, "Microencapsulated Bilberry and Chokeberry Leaf Extracts with Potential Health Benefits" in Plants, 12, no. 23 (2023):3979,
https://doi.org/10.3390/plants12233979 .,
https://hdl.handle.net/21.15107/rcub_dais_16163 .

TY  - JOUR
AU  - Maksimovic, Milica
AU  - Jovanović, Marina
AU  - Nikolić, Biljana
AU  - Tomić, Nina
AU  - Tenji, Dina
AU  - Stević, Tatjana
AU  - Mitić Ćulafić, Dragana
PY  - 2023
UR  - https://dais.sanu.ac.rs/123456789/14551
AB  - Persicaria amphibia (subfam. Polygonoideae), an aquatic macrophyte rich in dietary polyphenolics, is used as a traditional remedy and culinary herb. Nevertheless, P. amphibia from the Balkan region has been insufficiently studied and underutilized. Here, the cytotoxicity and antimicrobial properties of the previously chemically characterised ethanol extract of P. amphibia aerial parts were tested. The following methods were carried out: the MTT assay, qRT-PCR, microdilution assay, Chromobacterium violaceum screening assay (monitoring of quorum sensing, QS) and the agar plating method (antifungal activity). The study was conducted to determine the cytotoxic effects of P. amphibia against lung cancer cells (A549) and its combination with cytostatic doxorubicin (Dox). A dose-dependent decrease in cell viability (up to 82% reduction) and additive interactions of the tested agents were noted. Both alone and combined with Dox, P. amphibia reduced the expression of Nrf2 (p < 0.05). In terms of antimicrobial effects, P. amphibia exhibited an antipathogenic effect since it disrupted QS communication, which was evident through the inhibition of violacein production of C. violaceum CV025. The antifungal screening revealed that P. amphibia induced significant growth inhibition of Aspergillus spp. (28.23%). Based on the obtained results, further examination of the potential use of P. amphibia in modern phytotherapy and diet-derived cancer chemoprevention is encouraged.
PB  - Belgrade : 	Institute of Botany and Botanical Garden Jevremovac (University of Belgrade - Faculty of Biology)
T2  - Botanica Serbica
T1  - Persicaria amphibia, an old traditional remedy and wild edible herb: In vitro evaluation of cytotoxicity and antimicrobial properties
SP  - 1
EP  - 8
VL  - 47
IS  - 1
DO  - 10.2298/BOTSERB2301001M
UR  - https://hdl.handle.net/21.15107/rcub_dais_14551
ER  - 

@article{
author = "Maksimovic, Milica and Jovanović, Marina and Nikolić, Biljana and Tomić, Nina and Tenji, Dina and Stević, Tatjana and Mitić Ćulafić, Dragana",
year = "2023",
abstract = "Persicaria amphibia (subfam. Polygonoideae), an aquatic macrophyte rich in dietary polyphenolics, is used as a traditional remedy and culinary herb. Nevertheless, P. amphibia from the Balkan region has been insufficiently studied and underutilized. Here, the cytotoxicity and antimicrobial properties of the previously chemically characterised ethanol extract of P. amphibia aerial parts were tested. The following methods were carried out: the MTT assay, qRT-PCR, microdilution assay, Chromobacterium violaceum screening assay (monitoring of quorum sensing, QS) and the agar plating method (antifungal activity). The study was conducted to determine the cytotoxic effects of P. amphibia against lung cancer cells (A549) and its combination with cytostatic doxorubicin (Dox). A dose-dependent decrease in cell viability (up to 82% reduction) and additive interactions of the tested agents were noted. Both alone and combined with Dox, P. amphibia reduced the expression of Nrf2 (p < 0.05). In terms of antimicrobial effects, P. amphibia exhibited an antipathogenic effect since it disrupted QS communication, which was evident through the inhibition of violacein production of C. violaceum CV025. The antifungal screening revealed that P. amphibia induced significant growth inhibition of Aspergillus spp. (28.23%). Based on the obtained results, further examination of the potential use of P. amphibia in modern phytotherapy and diet-derived cancer chemoprevention is encouraged.",
publisher = "Belgrade : 	Institute of Botany and Botanical Garden Jevremovac (University of Belgrade - Faculty of Biology)",
journal = "Botanica Serbica",
title = "Persicaria amphibia, an old traditional remedy and wild edible herb: In vitro evaluation of cytotoxicity and antimicrobial properties",
pages = "1-8",
volume = "47",
number = "1",
doi = "10.2298/BOTSERB2301001M",
url = "https://hdl.handle.net/21.15107/rcub_dais_14551"
}

Maksimovic, M., Jovanović, M., Nikolić, B., Tomić, N., Tenji, D., Stević, T.,& Mitić Ćulafić, D.. (2023). Persicaria amphibia, an old traditional remedy and wild edible herb: In vitro evaluation of cytotoxicity and antimicrobial properties. in Botanica Serbica
Belgrade : 	Institute of Botany and Botanical Garden Jevremovac (University of Belgrade - Faculty of Biology)., 47(1), 1-8.
https://doi.org/10.2298/BOTSERB2301001M
https://hdl.handle.net/21.15107/rcub_dais_14551

Maksimovic M, Jovanović M, Nikolić B, Tomić N, Tenji D, Stević T, Mitić Ćulafić D. Persicaria amphibia, an old traditional remedy and wild edible herb: In vitro evaluation of cytotoxicity and antimicrobial properties. in Botanica Serbica. 2023;47(1):1-8.
doi:10.2298/BOTSERB2301001M
https://hdl.handle.net/21.15107/rcub_dais_14551 .

Maksimovic, Milica, Jovanović, Marina, Nikolić, Biljana, Tomić, Nina, Tenji, Dina, Stević, Tatjana, Mitić Ćulafić, Dragana, "Persicaria amphibia, an old traditional remedy and wild edible herb: In vitro evaluation of cytotoxicity and antimicrobial properties" in Botanica Serbica, 47, no. 1 (2023):1-8,
https://doi.org/10.2298/BOTSERB2301001M .,
https://hdl.handle.net/21.15107/rcub_dais_14551 .