TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Ignjatović, Nenad
AU  - Savić, Vojin
AU  - Mihailović, Dragan
AU  - Uskoković, Dragan
PY  - 2012
UR  - https://dais.sanu.ac.rs/123456789/454
AB  - Increased life expectancy in developed countries leads to an increase in the number of musculoskeletal disorders, such as osteoporosis, oasteoratritis thus compromising good dental treatment. There are many drug delivery systems based on hydroxyapatite used in bone tissue regeneration. Vitamin D3 is osteodiferentiation factor which regulates bone formation by increasing osteoblast differentiation and bone mineralization. The aim of this study is to examine new multifunctional nanoparticulate system for local delivery of active form of vitamin D3 by biochemical blood marker and histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks, which have been implanted biomaterials in the artificial bone defect. Biochemical markers of osteogenesis were statistically significant after only 6 weeks of implantation. ALP activity in bone tissue was showed by histochemical analysis as well as high level reparatory skills. Local realized Vitamin D3 contribute to bone formation by increasing osteoblast differentiation and bone mineralization.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts
T1  - Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3
SP  - 121
EP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_dais_454
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Ignjatović, Nenad and Savić, Vojin and Mihailović, Dragan and Uskoković, Dragan",
year = "2012",
abstract = "Increased life expectancy in developed countries leads to an increase in the number of musculoskeletal disorders, such as osteoporosis, oasteoratritis thus compromising good dental treatment. There are many drug delivery systems based on hydroxyapatite used in bone tissue regeneration. Vitamin D3 is osteodiferentiation factor which regulates bone formation by increasing osteoblast differentiation and bone mineralization. The aim of this study is to examine new multifunctional nanoparticulate system for local delivery of active form of vitamin D3 by biochemical blood marker and histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks, which have been implanted biomaterials in the artificial bone defect. Biochemical markers of osteogenesis were statistically significant after only 6 weeks of implantation. ALP activity in bone tissue was showed by histochemical analysis as well as high level reparatory skills. Local realized Vitamin D3 contribute to bone formation by increasing osteoblast differentiation and bone mineralization.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts",
title = "Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3",
pages = "121-121",
url = "https://hdl.handle.net/21.15107/rcub_dais_454"
}

Ajduković, Z., Petrović, M. B., Ignjatović, N., Savić, V., Mihailović, D.,& Uskoković, D.. (2012). Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3. in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 121-121.
https://hdl.handle.net/21.15107/rcub_dais_454

Ajduković Z, Petrović MB, Ignjatović N, Savić V, Mihailović D, Uskoković D. Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3. in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts. 2012;:121-121.
https://hdl.handle.net/21.15107/rcub_dais_454 .

Ajduković, Zorica, Petrović, Milica B., Ignjatović, Nenad, Savić, Vojin, Mihailović, Dragan, Uskoković, Dragan, "Regeneration bone tissue by new nanoparticules system based on hydroxiapatite as systems for local delivery of vitamin D3" in The Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstracts (2012):121-121,
https://hdl.handle.net/21.15107/rcub_dais_454 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, Nadica
AU  - Ignjatović, Nenad
AU  - Savić, Vojin
AU  - Najman, Stevo
AU  - Mihailović, Dragan
AU  - Vasiljević, Perica
AU  - Uskoković, Dragan
PY  - 2011
UR  - https://dais.sanu.ac.rs/123456789/674
AB  - One of the trends in the treatment of reduced bone density is in oral implantology through the use of new biomaterials with paramagnetic properties. In this in vivo study the effect of Ca /Co-HAp nanoparticles (calcium/cobalt-hydroxiapatite) in the regeneration of the reduced alveolar bone density in experimental animals was examined by analyzing both the biochemical and histochemical markers and through analysis of alveolar bone density. The research was carried out on female Westar rats, aged 6-8 weeks, whom have been implanted nanobiomaterial in reduced alveolar bone density. Good results in regeneration of reduced bone density were achieved in six weeks after implantation of the nanoparticles with paramagnetic properties. Biochemical markers of osteogenesis showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect, while X-ray analyses evidenced rise of bone density. Implantation of Ca/Co-Hap enables rapid new formation, thus becoming the material of choice for accelerated reduced bone density regeneration.
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts
T1  - Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density
SP  - 161
EP  - 161
UR  - https://hdl.handle.net/21.15107/rcub_dais_674
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, Nadica and Ignjatović, Nenad and Savić, Vojin and Najman, Stevo and Mihailović, Dragan and Vasiljević, Perica and Uskoković, Dragan",
year = "2011",
abstract = "One of the trends in the treatment of reduced bone density is in oral implantology through the use of new biomaterials with paramagnetic properties. In this in vivo study the effect of Ca /Co-HAp nanoparticles (calcium/cobalt-hydroxiapatite) in the regeneration of the reduced alveolar bone density in experimental animals was examined by analyzing both the biochemical and histochemical markers and through analysis of alveolar bone density. The research was carried out on female Westar rats, aged 6-8 weeks, whom have been implanted nanobiomaterial in reduced alveolar bone density. Good results in regeneration of reduced bone density were achieved in six weeks after implantation of the nanoparticles with paramagnetic properties. Biochemical markers of osteogenesis showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect, while X-ray analyses evidenced rise of bone density. Implantation of Ca/Co-Hap enables rapid new formation, thus becoming the material of choice for accelerated reduced bone density regeneration.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts",
title = "Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density",
pages = "161-161",
url = "https://hdl.handle.net/21.15107/rcub_dais_674"
}

Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Savić, V., Najman, S., Mihailović, D., Vasiljević, P.,& Uskoković, D.. (2011). Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density. in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 161-161.
https://hdl.handle.net/21.15107/rcub_dais_674

Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Savić V, Najman S, Mihailović D, Vasiljević P, Uskoković D. Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density. in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts. 2011;:161-161.
https://hdl.handle.net/21.15107/rcub_dais_674 .

Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, Nadica, Ignjatović, Nenad, Savić, Vojin, Najman, Stevo, Mihailović, Dragan, Vasiljević, Perica, Uskoković, Dragan, "Paramagnetic nanoparticles in the regeneration of the reduced alveolar bone density" in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts (2011):161-161,
https://hdl.handle.net/21.15107/rcub_dais_674 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, Nadica
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin P.
PY  - 2010
UR  - https://dais.sanu.ac.rs/123456789/3446
AB  - This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the mineralized tissues. It can be concluded that Ca/Co-HAp stimulates the regeneration of osteoporotic alveolar bone in tested animals as confirmed by the increased levels of biochemical blood markers and through histochemical analysis. Therefore, it can be concluded that Ca/Co-HAp nanocomposite should be choise material in the osteoconstructive processes in the future.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 19
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_dais_3446
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, Nadica and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin P.",
year = "2010",
abstract = "This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the mineralized tissues. It can be concluded that Ca/Co-HAp stimulates the regeneration of osteoporotic alveolar bone in tested animals as confirmed by the increased levels of biochemical blood markers and through histochemical analysis. Therefore, it can be concluded that Ca/Co-HAp nanocomposite should be choise material in the osteoconstructive processes in the future.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "19-19",
url = "https://hdl.handle.net/21.15107/rcub_dais_3446"
}

Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V. P.. (2010). Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 19-19.
https://hdl.handle.net/21.15107/rcub_dais_3446

Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić VP. Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:19-19.
https://hdl.handle.net/21.15107/rcub_dais_3446 .

Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, Nadica, Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin P., "Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):19-19,
https://hdl.handle.net/21.15107/rcub_dais_3446 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Đorđević, Nadica
AU  - Mladenović Antić, Snežana
AU  - Kocić, Branislava
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin P.
PY  - 2010
UR  - https://dais.sanu.ac.rs/123456789/3444
AB  - Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted calcium hydroxyapatite nanopowders and biphased calciumphosphate/ poli-lactide-co-glicolide. The antimicrobial effects of these substances (powders) against two pathogen bacterial strains- Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were tested by disc diffusion method and quantitative antimicrobial test in liquid medium. It was noted that the inhibition zone of the bacterial cells S. aureus around the sample of the Ca/Co- HAp, was a lot bigger compared to the inhibition zone of bacterial cells E. coli around the sample of the mentioned biomaterial, which means that this material has bigger antimicrobic activity on S. aureus, in relation to E. coli. Quantitative antimicrobial test in liquid medium demonstrate that cobalt-substituted calcium hydroxyapatite samples show viable cells reduction of both tested microorganisms. It may be concluded that nanoparticles of cobalt-substituted calcium hydoxyapatite nano-powders has a satisfactory antimicrobic activity according to the tested bacteria strain.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
T1  - In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite
SP  - 18
EP  - 18
UR  - https://hdl.handle.net/21.15107/rcub_dais_3444
ER  - 

@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Đorđević, Nadica and Mladenović Antić, Snežana and Kocić, Branislava and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin P.",
year = "2010",
abstract = "Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted calcium hydroxyapatite nanopowders and biphased calciumphosphate/ poli-lactide-co-glicolide. The antimicrobial effects of these substances (powders) against two pathogen bacterial strains- Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were tested by disc diffusion method and quantitative antimicrobial test in liquid medium. It was noted that the inhibition zone of the bacterial cells S. aureus around the sample of the Ca/Co- HAp, was a lot bigger compared to the inhibition zone of bacterial cells E. coli around the sample of the mentioned biomaterial, which means that this material has bigger antimicrobic activity on S. aureus, in relation to E. coli. Quantitative antimicrobial test in liquid medium demonstrate that cobalt-substituted calcium hydroxyapatite samples show viable cells reduction of both tested microorganisms. It may be concluded that nanoparticles of cobalt-substituted calcium hydoxyapatite nano-powders has a satisfactory antimicrobic activity according to the tested bacteria strain.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia",
title = "In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite",
pages = "18-18",
url = "https://hdl.handle.net/21.15107/rcub_dais_3444"
}

Ajduković, Z., Milićević, J., Petrović, M. B., Đorđević, N., Mladenović Antić, S., Kocić, B., Ignjatović, N., Uskoković, D.,& Savić, V. P.. (2010). In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 18-18.
https://hdl.handle.net/21.15107/rcub_dais_3444

Ajduković Z, Milićević J, Petrović MB, Đorđević N, Mladenović Antić S, Kocić B, Ignjatović N, Uskoković D, Savić VP. In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite. in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia. 2010;:18-18.
https://hdl.handle.net/21.15107/rcub_dais_3444 .

Ajduković, Zorica, Milićević, Jelena, Petrović, Milica B., Đorđević, Nadica, Mladenović Antić, Snežana, Kocić, Branislava, Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin P., "In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite" in Program and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbia (2010):18-18,
https://hdl.handle.net/21.15107/rcub_dais_3444 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Savić, Vojin P.
AU  - Uskoković, Dragan
PY  - 2010
UR  - https://dais.sanu.ac.rs/123456789/3553
AB  - Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- hydroxyapatite and biphasic calcium phosphate/ poly (lactide-co-glycolide) composite biomaterial. Antimicrobial activity of the samples was tested using dilution method and disk diffusion. The results of antimicrobial tests were obtained by determining the reduction percentage the number of bacteria in physiological solution where bacteria cells were exposed to the samples. It can be concluded that synthesized HAp biomaterials have satisfactory antimicrobial activity against tested bacteria strains.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro
SP  - 168
EP  - 168
UR  - https://hdl.handle.net/21.15107/rcub_dais_3553
ER  - 

@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Đorđević, N. and Ignjatović, Nenad and Savić, Vojin P. and Uskoković, Dragan",
year = "2010",
abstract = "Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- hydroxyapatite and biphasic calcium phosphate/ poly (lactide-co-glycolide) composite biomaterial. Antimicrobial activity of the samples was tested using dilution method and disk diffusion. The results of antimicrobial tests were obtained by determining the reduction percentage the number of bacteria in physiological solution where bacteria cells were exposed to the samples. It can be concluded that synthesized HAp biomaterials have satisfactory antimicrobial activity against tested bacteria strains.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro",
pages = "168-168",
url = "https://hdl.handle.net/21.15107/rcub_dais_3553"
}

Ajduković, Z., Milićević, J., Petrović, M. B., Đorđević, N., Ignjatović, N., Savić, V. P.,& Uskoković, D.. (2010). Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 168-168.
https://hdl.handle.net/21.15107/rcub_dais_3553

Ajduković Z, Milićević J, Petrović MB, Đorđević N, Ignjatović N, Savić VP, Uskoković D. Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:168-168.
https://hdl.handle.net/21.15107/rcub_dais_3553 .

Ajduković, Zorica, Milićević, Jelena, Petrović, Milica B., Đorđević, N., Ignjatović, Nenad, Savić, Vojin P., Uskoković, Dragan, "Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):168-168,
https://hdl.handle.net/21.15107/rcub_dais_3553 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Đorđević, N.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Savić, Vojin
PY  - 2010
UR  - https://dais.sanu.ac.rs/123456789/3552
AB  - One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
T1  - Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles
SP  - 167
EP  - 167
UR  - https://hdl.handle.net/21.15107/rcub_dais_3552
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Đorđević, N. and Ignjatović, Nenad and Uskoković, Dragan and Savić, Vojin",
year = "2010",
abstract = "One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution through the use of various biomaterials. Most researchers focus on the synthesis of the nanomaterials with magnetic and paramagnetic properties. The aim of this study is to examine the role of Ca / Co-HAp nanoparticles in the regeneration of the osteoporotic alveolar bone in experimental animals by analyzing the biochemical blood markers (ALP, Ca, Mg, and P) and through histochemical analysis. The research was carried out on female Westar rats, aged 6-8 weeks. The obtained results for the biochemical blood markers showed statistically significant rise. Histological analysis revealed high level reparatory skills of the biocomposite implanted in the bone defect as early as in the 6th week of the experiment as well as an increased alkaline phosphatase activity in the mineralized tissues. The implantation of the biomaterials facilitates osteogenesis, justifying their use in the accelerated regeneration treatment of the osteoporotic alveolar bone.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010",
title = "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles",
pages = "167-167",
url = "https://hdl.handle.net/21.15107/rcub_dais_3552"
}

Ajduković, Z., Petrović, M. B., Milićević, J., Đorđević, N., Ignjatović, N., Uskoković, D.,& Savić, V.. (2010). Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010
Belgrade : Institute of Technical Sciences of SASA., 167-167.
https://hdl.handle.net/21.15107/rcub_dais_3552

Ajduković Z, Petrović MB, Milićević J, Đorđević N, Ignjatović N, Uskoković D, Savić V. Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles. in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010. 2010;:167-167.
https://hdl.handle.net/21.15107/rcub_dais_3552 .

Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Đorđević, N., Ignjatović, Nenad, Uskoković, Dragan, Savić, Vojin, "Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles" in Programme and The Book of Abstracts / Twelfth Annual Conference YUCOMAT 2010, Herceg Novi, September 6–10, 2010 (2010):167-167,
https://hdl.handle.net/21.15107/rcub_dais_3552 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Milićević, Jelena
AU  - Petrović, Milica B.
AU  - Savić, Vojin
AU  - Ignjatović, Nenad
PY  - 2009
UR  - https://dais.sanu.ac.rs/123456789/4933
AB  - Istraživanje je sprovedeno sa ciljem da se dokaže aktivnost alkalne fosfataze, lokalizovane u dekalcifikovanoj kosti, uzete sa leve strane mandibule pacova, u kojoj je arteficijalno napravljen defekt i implantiran nano kalcijum-kobalt hidroksiapatit. Studija je obuhvatila 48 životinja, starosti 6-8 nedelja. Posle šest i dvadeset četiri nedelje od implantacije biomaterijala, uzeti su uzorci za histohemijsku analizu i fiksirani u PLP fiksativu. Zatim su dekalcifikovani, ukalupljeni u parafinski blok i obrađivani za svetlosno-mikroskopska ispitivanja i histohemijsko dokazivanje aktivnosti alkalne fosfataze. Histološka analiza je pokazala visok stepen reparatornih sposobnosti ugrađenog biokompozita u koštani defekat. Histohemijskom analizom je dokazana aktivnost alkalne fosfataze u mineralizovanom tkivu.
PB  - Beograd : Institut tehničkih nauka
C3  - Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009
T1  - Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita
SP  - 20
EP  - 20
UR  - https://hdl.handle.net/21.15107/rcub_dais_4933
ER  - 

@conference{
author = "Ajduković, Zorica and Milićević, Jelena and Petrović, Milica B. and Savić, Vojin and Ignjatović, Nenad",
year = "2009",
abstract = "Istraživanje je sprovedeno sa ciljem da se dokaže aktivnost alkalne fosfataze, lokalizovane u dekalcifikovanoj kosti, uzete sa leve strane mandibule pacova, u kojoj je arteficijalno napravljen defekt i implantiran nano kalcijum-kobalt hidroksiapatit. Studija je obuhvatila 48 životinja, starosti 6-8 nedelja. Posle šest i dvadeset četiri nedelje od implantacije biomaterijala, uzeti su uzorci za histohemijsku analizu i fiksirani u PLP fiksativu. Zatim su dekalcifikovani, ukalupljeni u parafinski blok i obrađivani za svetlosno-mikroskopska ispitivanja i histohemijsko dokazivanje aktivnosti alkalne fosfataze. Histološka analiza je pokazala visok stepen reparatornih sposobnosti ugrađenog biokompozita u koštani defekat. Histohemijskom analizom je dokazana aktivnost alkalne fosfataze u mineralizovanom tkivu.",
publisher = "Beograd : Institut tehničkih nauka",
journal = "Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009",
title = "Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita",
pages = "20-20",
url = "https://hdl.handle.net/21.15107/rcub_dais_4933"
}

Ajduković, Z., Milićević, J., Petrović, M. B., Savić, V.,& Ignjatović, N.. (2009). Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita. in Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009
Beograd : Institut tehničkih nauka., 20-20.
https://hdl.handle.net/21.15107/rcub_dais_4933

Ajduković Z, Milićević J, Petrović MB, Savić V, Ignjatović N. Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita. in Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009. 2009;:20-20.
https://hdl.handle.net/21.15107/rcub_dais_4933 .

Ajduković, Zorica, Milićević, Jelena, Petrović, Milica B., Savić, Vojin, Ignjatović, Nenad, "Aktivnost alkalne fosfataze u kosti nakon implantacije nanočestičnog kalcijum-kobalt hidroksiapatita" in Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009 (2009):20-20,
https://hdl.handle.net/21.15107/rcub_dais_4933 .

TY  - CONF
AU  - Ajduković, Zorica
AU  - Petrović, Milica B.
AU  - Milićević, Jelena
AU  - Savić, Vojin
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2009
UR  - https://dais.sanu.ac.rs/123456789/4929
AB  - Osteoporoza kao bolest savremene civilizacije postaje sve aktuelnija u stomatologiji. Jedan od trendova u nalaženju rešenja je u oralnoj implantologiji kroz primenu biomaterijala sa magnetnim česticama. U ovoj studiji ispitivan je uticaj nanočestica Ca/Co-HAp na regeneraciju osteoporotične alveolarne kosti eksperimentalnih životinja analizom biohemijskih markera krvi (Ca, Mg, P). Istraživanje je sprovedeno na 48 Wistar pacovima, starosti 6-8 nedelja kojima je implantiran biometrijal u osteoprotičnoj alveolarnoj kosti. Dobri rezultati regeneracije osteoporotičnog tkiva su postignuti 6 nedelja nakon implantacije nanočestica. Biohemijski parametri koštane sinteze su u statistički značajnom porastu. Implantacija biomaterijala omogućava brzo formiranje nove kosti što ih čini materijalima izbora za ubrzanu regeneraciju kosti.
PB  - Beograd : Institut tehničkih nauka
C3  - Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.
T1  - Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice
SP  - 19
EP  - 19
UR  - https://hdl.handle.net/21.15107/rcub_dais_4929
ER  - 

@conference{
author = "Ajduković, Zorica and Petrović, Milica B. and Milićević, Jelena and Savić, Vojin and Ignjatović, Nenad and Uskoković, Dragan",
year = "2009",
abstract = "Osteoporoza kao bolest savremene civilizacije postaje sve aktuelnija u stomatologiji. Jedan od trendova u nalaženju rešenja je u oralnoj implantologiji kroz primenu biomaterijala sa magnetnim česticama. U ovoj studiji ispitivan je uticaj nanočestica Ca/Co-HAp na regeneraciju osteoporotične alveolarne kosti eksperimentalnih životinja analizom biohemijskih markera krvi (Ca, Mg, P). Istraživanje je sprovedeno na 48 Wistar pacovima, starosti 6-8 nedelja kojima je implantiran biometrijal u osteoprotičnoj alveolarnoj kosti. Dobri rezultati regeneracije osteoporotičnog tkiva su postignuti 6 nedelja nakon implantacije nanočestica. Biohemijski parametri koštane sinteze su u statistički značajnom porastu. Implantacija biomaterijala omogućava brzo formiranje nove kosti što ih čini materijalima izbora za ubrzanu regeneraciju kosti.",
publisher = "Beograd : Institut tehničkih nauka",
journal = "Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.",
title = "Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice",
pages = "19-19",
url = "https://hdl.handle.net/21.15107/rcub_dais_4929"
}

Ajduković, Z., Petrović, M. B., Milićević, J., Savić, V., Ignjatović, N.,& Uskoković, D.. (2009). Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice. in Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.
Beograd : Institut tehničkih nauka., 19-19.
https://hdl.handle.net/21.15107/rcub_dais_4929

Ajduković Z, Petrović MB, Milićević J, Savić V, Ignjatović N, Uskoković D. Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice. in Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009.. 2009;:19-19.
https://hdl.handle.net/21.15107/rcub_dais_4929 .

Ajduković, Zorica, Petrović, Milica B., Milićević, Jelena, Savić, Vojin, Ignjatović, Nenad, Uskoković, Dragan, "Kalcijum/kobalt hidroksiapatit nanočestice u regeneraciji osteoporotične kosti donje vilice" in Program i knjiga apstrakata / Osma konferencija mladih istraživača Nauka i inženjerstvo novih materijala, Beograd, 21–23. decembar 2009. (2009):19-19,
https://hdl.handle.net/21.15107/rcub_dais_4929 .