Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors
Samo za registrovane korisnike
2018
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
Ključne reči:
biosensors / competitive adsorption / deterministic time response / stochastic time responseIzvor:
Materials Today: Proceedings, 2018, 5, 8, Part 2, 16006-16011Izdavač:
- Elsevier
Finansiranje / projekti:
- Mikro, nano-sistemi i senzori za primenu u elektroprivredi, procesnoj industriji i zaštiti životne sredine (RS-MESTD-Technological Development (TD or TR)-32008)
DOI: 10.1016/j.matpr.2018.05.045
ISSN: 2214-7853
WoS: 000441006800008
Scopus: 2-s2.0-85056510161
URI
http://www.sciencedirect.com/science/article/pii/S2214785318309167https://dais.sanu.ac.rs/123456789/4550
Institucija/grupa
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - JOUR AU - Jokić, Ivana AU - Đurić, Zoran G. AU - Radulović, Katarina AU - Frantlović, Miloš PY - 2018 UR - http://www.sciencedirect.com/science/article/pii/S2214785318309167 UR - https://dais.sanu.ac.rs/123456789/4550 AB - We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions. PB - Elsevier T2 - Materials Today: Proceedings T1 - Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors SP - 16006 EP - 16011 VL - 5 IS - 8, Part 2 DO - 10.1016/j.matpr.2018.05.045 UR - https://hdl.handle.net/21.15107/rcub_dais_4550 ER -
@article{ author = "Jokić, Ivana and Đurić, Zoran G. and Radulović, Katarina and Frantlović, Miloš", year = "2018", abstract = "We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.", publisher = "Elsevier", journal = "Materials Today: Proceedings", title = "Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors", pages = "16006-16011", volume = "5", number = "8, Part 2", doi = "10.1016/j.matpr.2018.05.045", url = "https://hdl.handle.net/21.15107/rcub_dais_4550" }
Jokić, I., Đurić, Z. G., Radulović, K.,& Frantlović, M.. (2018). Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors. in Materials Today: Proceedings Elsevier., 5(8, Part 2), 16006-16011. https://doi.org/10.1016/j.matpr.2018.05.045 https://hdl.handle.net/21.15107/rcub_dais_4550
Jokić I, Đurić ZG, Radulović K, Frantlović M. Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors. in Materials Today: Proceedings. 2018;5(8, Part 2):16006-16011. doi:10.1016/j.matpr.2018.05.045 https://hdl.handle.net/21.15107/rcub_dais_4550 .
Jokić, Ivana, Đurić, Zoran G., Radulović, Katarina, Frantlović, Miloš, "Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors" in Materials Today: Proceedings, 5, no. 8, Part 2 (2018):16006-16011, https://doi.org/10.1016/j.matpr.2018.05.045 ., https://hdl.handle.net/21.15107/rcub_dais_4550 .