The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles
Konferencijski prilog (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
As the most abundant protein in the human body, collagen has been drawing the attention of many researchers from the biomedical field for a long time. It can be found as a constituent in versatile commercially available products. In the hydrogel form, it is used often in designing novel platforms for drug delivery or cell growth. On the other side, Selenium nanoparticles (SeNPs) are a relatively new selenium form that has proven records in enhanced antimicrobial, anticancer, antiviral, antioxidative activity, and reduced toxicity compared to other selenium forms. Therefore, in this work, we have examined the effects of different stabilizing agents, used in the preparation of selenium nanoparticles, on the formation, structure, and biocompatibility of composite hydrogel Collagen/SeNPs. Differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), optical microscopy, and cell viability (MTT assay) were used for the characterizations of obtained hydrogels. SeNPs... were synthesized by the chemical reduction in the form of colloidal solutions using (i) bovine serum albumin, (ii) chitosan, and(iii) glucose as stabilizing agents.
Ključne reči:
collagen/selenium nanoparticles / antioxidative activity / toxicityIzvor:
The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles, 2023, 86-86Izdavač:
- Belgrade : Serbian Ceramic Society
Institucija/grupa
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - CONF AU - Kuzmanović, Maja AU - Filipović, Nenad AU - Tomić, Nina AU - Stevanović, Magdalena PY - 2023 UR - https://dais.sanu.ac.rs/123456789/15225 AB - As the most abundant protein in the human body, collagen has been drawing the attention of many researchers from the biomedical field for a long time. It can be found as a constituent in versatile commercially available products. In the hydrogel form, it is used often in designing novel platforms for drug delivery or cell growth. On the other side, Selenium nanoparticles (SeNPs) are a relatively new selenium form that has proven records in enhanced antimicrobial, anticancer, antiviral, antioxidative activity, and reduced toxicity compared to other selenium forms. Therefore, in this work, we have examined the effects of different stabilizing agents, used in the preparation of selenium nanoparticles, on the formation, structure, and biocompatibility of composite hydrogel Collagen/SeNPs. Differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), optical microscopy, and cell viability (MTT assay) were used for the characterizations of obtained hydrogels. SeNPs were synthesized by the chemical reduction in the form of colloidal solutions using (i) bovine serum albumin, (ii) chitosan, and(iii) glucose as stabilizing agents. PB - Belgrade : Serbian Ceramic Society C3 - The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles T1 - The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles SP - 86 EP - 86 UR - https://hdl.handle.net/21.15107/rcub_dais_15225 ER -
@conference{ author = "Kuzmanović, Maja and Filipović, Nenad and Tomić, Nina and Stevanović, Magdalena", year = "2023", abstract = "As the most abundant protein in the human body, collagen has been drawing the attention of many researchers from the biomedical field for a long time. It can be found as a constituent in versatile commercially available products. In the hydrogel form, it is used often in designing novel platforms for drug delivery or cell growth. On the other side, Selenium nanoparticles (SeNPs) are a relatively new selenium form that has proven records in enhanced antimicrobial, anticancer, antiviral, antioxidative activity, and reduced toxicity compared to other selenium forms. Therefore, in this work, we have examined the effects of different stabilizing agents, used in the preparation of selenium nanoparticles, on the formation, structure, and biocompatibility of composite hydrogel Collagen/SeNPs. Differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), optical microscopy, and cell viability (MTT assay) were used for the characterizations of obtained hydrogels. SeNPs were synthesized by the chemical reduction in the form of colloidal solutions using (i) bovine serum albumin, (ii) chitosan, and(iii) glucose as stabilizing agents.", publisher = "Belgrade : Serbian Ceramic Society", journal = "The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles", title = "The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles", pages = "86-86", url = "https://hdl.handle.net/21.15107/rcub_dais_15225" }
Kuzmanović, M., Filipović, N., Tomić, N.,& Stevanović, M.. (2023). The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles. in The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles Belgrade : Serbian Ceramic Society., 86-86. https://hdl.handle.net/21.15107/rcub_dais_15225
Kuzmanović M, Filipović N, Tomić N, Stevanović M. The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles. in The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles. 2023;:86-86. https://hdl.handle.net/21.15107/rcub_dais_15225 .
Kuzmanović, Maja, Filipović, Nenad, Tomić, Nina, Stevanović, Magdalena, "The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles" in The effect of stabilizing agents on physicochemical properties and cell viability of composite hydrogel Collagen/Selenium nanoparticles (2023):86-86, https://hdl.handle.net/21.15107/rcub_dais_15225 .