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Determination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometry
(Belgrade : Institute of Technical Sciences of SASA, 2010)
Clindamycin was determined in pig plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS). The multiple reaction monitoring (MRM) mode of precursor-product ion transitions for clindamycin (m/z=421.1/126.1) and ...
Hydrothermal synthesis of zirconium substituted hydroxyapatite
(Belgrade : Materials Research Society of Serbia, 2011)
Aim of work is to investigate an efficiency of hydrothermal treatment on formation of zirconium substituted hydroxyapatite Ca5-xZrx(PO4)3OH. A set of trial was conducted to optimize process and find substitution limit. ...
Synthesis, characterization and sintering properties of Zr-doped hydroxyapatite
(Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, 2011)
Improving of material characteristics could be achieved in different ways, but it is always connected with the issue of impairing the other functional properties. Hydroxyapatite bioceramics lacks of insufficient mechanical ...
Hemolytic activity of bioactive nanocomposites
(Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade, 2012)
Huge range of tested biomaterials in recent decades has emerged as an ideal scaffold for cell growth, but few have demonstrated clinical efficacy. Among them, synthetic hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the most ...
Surface modification of titanium implants by adherent hydroxyapatite/titanium oxide composite coatings using novel in-situ synthesis
(International Association of Physical Chemists, 2019)
The medical devices based on titanium and its alloys are widely used in the repair and replacement of a degraded or inhibited func-tion of locomotor system [1]. Ti and its alloys exhibit high mechanical strength, good ...
Cell-selective toxicity of hydroxyapatite-chitosan oligosaccharide lactate particles loaded with a steroid cancer inhibitor
(Belgrade : Materials Research Society of Serbia, 2018)
The applicative potential of synthetic calcium phosphates, especially hydroxyapatite (HAp), has become intensely broadened in the past 10 years, from bone tissue engineering to multiple other fields of biomedicine. Hybrid ...
Testing the antimicrobial activity of hydroxyapatite nanoparticles in vitro
(Belgrade : Institute of Technical Sciences of SASA, 2010)
Antimicrobial materials based on hydroxyapatite are very attractive for wide application in medicine and stomatology. The goal of this work was to test antimicrobial activity of hydroxyapatite nanoparticles Co/Ca- ...
The hydrothermal synthesis of 1d biomedical hydroxyapatite nanostructures
(Belgrade : Materials Research Society of Serbia, 2014)
1D hydroxyapatite nanostructures such as nanotubes, ultra long nanowires and other morphological varieties have been promising material for bone reconstruction and therapy. Advantages like high specific surface, packing ...
Hydroxyapatite nano particles doped with Gd3+, Yb3+/Tm3+ and Eu3+ as lumino-magnetic multimodal contrast agents
(Belgrade : Materials Research Society of Serbia, 2019)
Hydroxyapatite (HAp) has been widely used as bone reconstruction materials due to their similarity to bone tissue. The improvement of HAp properties was achieved by doping its crystal lattice with different ions. Lanthanides, ...
Highly selective anticancer activity of core shell particles based on hydroxyapatite, chitosan lactate and different androstane derivatives
(Belgrade : Materials Research Society of Serbia, 2017)
Hybrid systems based on nano hydroxyapatites (HAp) are the subject of numerous studies in preventive and regenerative medicine. Special interests are directed towards the creation of a system based on HAp for use in a ...