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dc.creatorVukelić, Marija Đ.
dc.creatorMitić, Žarko
dc.creatorMiljković, Miroslav
dc.creatorŽivković, Jelena M.
dc.creatorIgnjatović, Nenad
dc.creatorUskoković, Dragan
dc.date.accessioned2017-06-10T15:45:07Z
dc.date.issued2011
dc.identifier.issn0365-4478 (Print)
dc.identifier.issn1821-2794 (Online)
dc.identifier.urihttp://dais.sanu.ac.rs/123456789/701
dc.description.abstractThe purpose of biomaterials is to replace a part or a function of the body in a safe, physiologically and economically acceptable way. The process of the reconstruction of bone defects has always been a big problem in orthopedics and maxillofacial surgery. Since hydroxyapatite (HAp) was detected as a component, the predominant constituent and the integral element of Mammalian bones, the development of the phospate ceramics as potential materials for implantation was enabled. This study investigated whether and in which way biomaterial calcium hydroxyapatite/poly-L-lactide (HAp/PLLA) interacts with the ionic composition of the human plasma. The simulated body fluid (SBF) is an artificial fluid that has the ionic composition and ionic concentration similar to the human blood plasma. HAp/PLLA was incubated for 1, 2, 3 and 5 weeks in SBF. The surfaces of both treated and untreated materials were analyzed on a scanning electron microscopy (SEM), and were also exposed to the energy dispersive X-ray spectroscopy (EDS), while SBF was submitted to the measuring of pH and electrical conductivity. However, our results indicate that the degradational changes of the material HAp/PLLA in SBF start from the surface of the treated material and that observed changes are the consequence of dissolution of its polymer component and the precipitation of the material similar to hydroxyapatite on its surface. This material shows good characteristics that place it among good candidates for the application in orthopedics and maxillofacial surgery.en
dc.formatapplication/pdf
dc.languageen
dc.publisherNiš : University of Niš, Faculty of Medicine; Department of the Serbian Medical Society Niš
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45004/RS//
dc.rightsopenAccess
dc.sourceActa Medica Medianaeen
dc.subjectbiomaterials
dc.subjecthydroxyapatite
dc.subjectpoly-l-lactide
dc.subjectsimulated body fluid
dc.titleInteraction of biomaterial containing calcium hydroxyapatite/poly-l-lactide with simulated body fluiden
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractУскоковић, Драган; Вукелић, Марија; Митић, Жарко; Живковић, Јелена; Игњатовић, Ненад; Миљковић, Мирослав;
dc.citation.spage35
dc.citation.epage39
dc.citation.volume50
dc.citation.issue4
dc.identifier.doi10.5633/amm.2011.0406
dc.type.versionpublishedVersion
dc.identifier.fulltexthttp://dais.sanu.ac.rs/bitstream/id/6935/Vukelic_Acta Medica Medianae_50_4_2011.pdf


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