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dc.creatorFilipović, Nenad
dc.creatorStevanović, Magdalena
dc.creatorPavlović, Vladimir B.
dc.creatorRadulović, Aleksandra
dc.creatorStojanović, Zoran S.
dc.creatorUskoković, Dragan
dc.date.accessioned2017-06-10T15:45:07Z
dc.date.issued2011
dc.identifier.isbn9788680321271
dc.identifier.urihttp://dais.sanu.ac.rs/123456789/692
dc.description.abstractPoly-ε-caprolactone (PCL) is a semicrystalline, biodegradable and biocompatible polymer. Its advantages, as high permeability to small drug molecules, failure to generate an acidic environment during degradation (as compared to polylactides and polyglycolides) and a slow degradation rate, make this aliphatic polyester suitable for extended long-term delivery over a period of more than one year. In this study PCL particles were prepared by physicochemical method with solvent/nonsolvent systems. The synthetic polymer polyvinylpyrrolidone (PVP) and natural polymer poly (α, γ, L-glutamic acid) (PGA), were used as stabilizers and their influence on size and morphology of the particles was examined. The results were compared with those obtained without the use of stabilizers. Characterization of obtained particles was performed by Fourier transform infrared spectroscopy. The morphology and size distribution were determined using SEM and particle analyzer.en
dc.format(2011) 2-2
dc.formatapplication/pdf
dc.languageen
dc.publisherBelgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45004/RS//
dc.rightsopenAccess
dc.sourceProgram and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbiaen
dc.subjectpoly-ε-caprolactone
dc.subjectbiomaterials
dc.subjectpolyvinylpyrrolidone
dc.subjectpoly(α,γ,l-glutamic acid)en
dc.titleSynthesis and the effect of processing parameters on characteristics of poly-ε-caprolactone micro- and nanospheresen
dc.typeconferenceObject
dc.rights.licenseBY-NC-ND
dcterms.abstractПавловић, Владимир Б.; Радуловић, Aлександра; Стојановић, Зоран; Ускоковић, Драган; Стевановић, Магдалена; Филиповић, Ненад;
dc.citation.spage2
dc.citation.epage2
dc.type.versionpublishedVersion
dc.identifier.fulltexthttp://dais.sanu.ac.rs/bitstream/id/21659/689.pdf


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