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dc.creatorStojanović, S.
dc.creatorNajman, Stevo
dc.creatorAjduković, Zorica
dc.creatorIgnjatović, Nenad
dc.creatorUskoković, Dragan
dc.date.accessioned2017-06-10T15:45:07Z
dc.date.issued2012
dc.identifier.urihttp://dais.sanu.ac.rs/123456789/458
dc.description.abstractThe aim of this study was to compare the effects of two types of nanomaterials, cobalt-exchanged hydroxyapatite (CoHAp) and calcium phosphate/poly-(DL-lactide-co-glycolide) (CP/PLGA), on the viability of Saos-2 osteoblast-like cells, using MTT test. We have examined the suspension of this materials in the following concentrations: 1.6, 8, 40, 200, 1000 and 2500 μg/ml, as well as extracts in concentration range from 2,5% to 100%. Both materials showed cytotoxic effect at higher concentrations of suspension and extract, respectively, but they were not cytotoxic at lower concentrations. CP/PLGA acted stronger cytotoxic compared to CoHAp, regardless of whether it is examined suspension or extract. CoHAp in small concentrations of suspension and extract acted slightly stimulatory on cells. This suggests that CoHAp may have advantage for use in the in vivo systems.en
dc.format(2012) 126-126
dc.formatapplication/pdf
dc.languageen
dc.publisherBelgrade : Materials Research Society of Serbia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45004/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41017/RS//
dc.rightsopenAccess
dc.sourceThe Fourteenth Annual Conference YUCOMAT 2012: Programme and the Book of Abstractsen
dc.subjectnanomaterials
dc.subjectcobalt-exchanged hydroxyapatite
dc.subjectpoly-(DL-lactide-co-glycolide)
dc.titleComparative study of the effects of different nanomaterials on the viability of human osteoblast-like cellsen
dc.typeconferenceObject
dc.rights.licenseBY-NC-ND
dcterms.abstractСтојановић, С.; Ускоковић, Драган; Игњатовић, Ненад; Aјдуковић, Зорица; Најман, Стево;
dc.citation.spage126
dc.citation.epage126
dc.type.versionpublishedVersion
dc.identifier.fulltexthttp://dais.sanu.ac.rs/bitstream/handle/123456789/458/Stojanovic-Yucomat2012-126.pdf


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