Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors
Authorized Users Only
Article (Published version)
MetadataShow full item record
We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
Keywords:biosensors / competitive adsorption / deterministic time response / stochastic time response
Source:Materials Today: Proceedings, 2018, 5, 8, Part 2, 16006-16011
- Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection (RS-32008)