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dc.creatorVuković, Gorica
dc.creatorLazić, Sanja
dc.creatorŠunjka, Dragana
dc.creatorBursić, Vojislava
dc.creatorŠarčev, Ivan
dc.creatorVukomanović, Marija
dc.creatorIgnjatović, Nenad
dc.creatorUskoković, Dragan
dc.date.accessioned2018-07-06T13:17:09Z
dc.date.available2018-07-06T13:17:09Z
dc.date.issued2010
dc.identifier.isbn9788680321264
dc.identifier.urihttp://dais.sanu.ac.rs/123456789/3453
dc.description.abstractClindamycin was determined in pig plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS). The multiple reaction monitoring (MRM) mode of precursor-product ion transitions for clindamycin (m/z=421.1/126.1) and the internal standard, caffeine (m/z=192/125) was used. The samples were prepared by two methods: 0.1% formic acid in methanol and 1.5% trichloacetic acid. The recovery for the two preparation methods at 0.05mg/ml (n=6) was found to be for the first 104.3% and for the second method 106.5%, with repeatability RSD 1.1% and RSD 4.34%, respectively. The results of the comparison of the two different preparation methods of samples demonstrated that both methods were satisfactory.sr
dc.language.isoensr
dc.publisherBelgrade : Institute of Technical Sciences of SASAsr
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/142006/RS//sr
dc.rightsopenAccesssr
dc.sourceProgram and the Book of Abstracts / Ninth Young Researchers Conference Materials Sciences and Engineering, December 20–22, 2010, Belgrade, Serbiasr
dc.subjectLC-MS/MSsr
dc.subjectclindamycinsr
dc.subjectpoly(D,Llactide-co-glycolide)sr
dc.subjecthydroxyapatitesr
dc.subjectcore-shell nanoparticlessr
dc.titleDetermination of clindamycin in pig plasma after implantation of poly(D,Llactide-co-glycolide)/hydroxyapatite/clindamycin core–shell nanosphere by liquid chromatography-tandem mass spectrometrysr
dc.typeconferenceObjectsr
dc.rights.licenseBY-NC-NDsr
dcterms.abstractШарчев, Иван; Вукомановић, Марија; Игњатовић, Ненад; Ускоковић, Драган; Лазић, Сања; Шуњка, Драгана; Бурсић, Војислава; Вуковић, Горица;
dc.citation.spage19
dc.citation.epage19
dc.type.versionpublishedVersionsr
dc.identifier.fulltexthttp://dais.sanu.ac.rs/bitstream/handle/123456789/3453/Vukovic_9KMI_2010_IV-8.pdf


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